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Re: Hostility More Common in Young Heart Patients
| Sharon Hope | 20 Mar 2005 15:53 |
I didn't see "hostility" in any of the citations. Also, my interpretation from the small quote you offered would be consistent with an anger and indignation at the realization that they are affected by what they had perceived as an old person's disease - also anger at being forced to come to terms with their mortality. Further, and I am not implying that any of the people in this sample fall into this category, many people who used certain illegal drugs in their youth died of sudden cardiac death in their late 20's and 30's - again, these illicit drug users could have a level of anger - both causing the drug use and resulting from the drug use - not seen in the general population.
The terminology used by the medical researchers in association with low cholesterol was (and these are direct quotes from the conclusions of the abstracts of the published medical journal articles, not my words):
? The authors concluded that, among non-African-American children, low total cholesterol is associated with school suspension or expulsion and that low total cholesterol may be a risk factor for aggression or a risk marker for other biologic variables that predispose to aggression.
? A significant increase in SERT (Serotonin transporter) activity was detected only during the first month of simvastatin therapy. This finding suggests that within this period some patients could be vulnerable to depression, violence, or suicide.
? This paper reviews early biological risk factors for violence. These factors include . low cholesterol. A biopsychosocial violence mode is proposed.
? The results suggest that total cholesterol level may be a useful biological marker for the risk of suicide in depression patients.
? The results indicated that medication-free schizophrenic patients have statistically significant lower serum cholesterol and leptin levels compared with controls and the difference is obvious in suicide attempters compared with non-suicide attempters and in violent attempters than non-violent attempters.
? Patients with a violent suicidal attempt have significantly lower cholesterol levels than patients with non-violent attempts and the control subjects. Our findings suggest that suicide attempts should not be considered a homogeneous group. They are consistent with the theory that low levels of cholesterol are associated with increased tendency for impulsive behavior and aggression and contribute to a more violent pattern of suicidal behavior.
? . The TC (low total serum cholesterol) level seems to be a peripheral marker with prognostic value among boys with conduct disorder and antisocial male offenders.
? Our results confirm previous reports of lower serum cholesterol in attempted suicide. They are also indicative of an increased noradrenaline turnover in subjects who attempt suicide, at least within 24 hours after the attempt. Whether this activation precedes or follows the attempt because of the specific stress, can not be answered at present.
? Low cholesterol may effect serotonergic neuronal activity and some types of 5-HT receptors, then may be related to violent behavior during sleep.
? These findings are consistent with the cholesterol-serotonin hypothesis and with the substantive literature linking both aggression and depression to depressed central serotonergic activity.
? Adjusting for other factors, low cholesterol is associated with increased subsequent criminal violence.
? These findings suggest the possibility that serum cholesterol levels may be positively associated with serotonergic receptor function. The existence of such an association may provide an explanation for reported increases in depression, suicide and violence in individuals with low or lowered cholesterol.
? Our results showed that low serum cholesterol level is associated with the violence of the suicide attempt and not with the suicide attempt itself. Further investigations are necessary to determine the usefulness of this easily accessible parameter as a potential risk indicator for violent acts such as violent suicidal behavior in susceptible individuals.
? Men with a lower cholesterol level (< or =4.5 mmol/liter) have a higher prevalence of depressive symptoms than those with a cholesterol level between 6 and 7 mmol/liter. These data may be important in the ongoing debate on the putative association between low cholesterol levels and violent death.
> http://tinyurl.com/6jqh3 > [quoted text clipped - 6 lines] > > L. |
| listener | 20 Mar 2005 05:25 |
http://tinyurl.com/6jqh3
"The investigators found that the rate of hostility symptoms was more than three times higher in young patients, compared with elderly people with CAD. Young heart patients with signs of hostility tended to have higher cholesterol compared with young patients with few signs of hostility."
Sharon, shouldn't it have been LOWER?
L.
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