Re: Pravachol verses Lipitor ?
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Re: Pravachol verses Lipitor ?
| Steve Marcus | 13 Sep 2004 09:24 |
> >>>>Steve > >>>> [quoted text clipped - 29 lines] > "Again, for every person who cannot tolerate statins, there are > literally tens of thousands who can, do and benefit from statins." For g-d sakes, learn to read. There's nothing about "majority rules" in that. My point is that statins benefit the vast majority of people. They are not right for everyone, just as penicillin is not the antibiotic of choice for everyone, and just as caffein isn't a "drug" that I can tolerate given my propensity to a fatal cardiac arrhythmia. Anyone seeking to deprive that majority of these drugs, and/or to scare everyone away from using them, is barking up the wrong tree. The proper answer is full and total disclosure to everyone, and properly attentive followups from doctors who do not, as you posted in another post, do not to consider the statin when making their diagnosis when presented with a patient taking statins and having symptoms of potential statin induced side effects.
> So to rephrase: More people can tolerate statins, so stuff those that > can't, simple really. > Those that can tolerate statins don't have to worry, no need to mention > them. Bulls--t. I didn't write that, and if you think that I did, I feel sorry for your incapacity to read plain English for comprehension. It now seems to me that you perfectly well understand that *you* tolerated being ill-informed, and being misdiagnosed (even now you don't want to acknowledge that the misdiagnosis equated to malpractice), and you are feeling sorry for yourself. That's fine, but don't take a position calculated to injure the vast number of people who can tolerate statins, and be helped by them, because of the mistakes of your doctors and your attitude of tolerating them as though doctors are g-ds.
> What I wrote was that publishing information that is skewed > > and biased in order to scare people off of something that will help the vast [quoted text clipped - 9 lines] > > That is not so. > Yes it is. No it is not. Roulette is gambling without any foreknowledge at all. less than 1 in 35 that a particular number will come up, less than 50-50 of black or red, etc., and who knows where the ball will land next? And once it does, there are no "do overs." Prescribing drugs that may have side effects for a very small number of people is not roulette, provided that the patient is informed (forewarned), or bothers to demand the s/he be informed, the requisite monitoring program is put into practice and adhered to, and, in the event that the patient has what may be an adverse reaction, a doctor makes the correct diagnosis and changes the prescription, allowing the patient to avoid serious damage before the side effects become more serious and/or permanent (you get to "do it over").
> For many, if not most (I don't have exact numbers), side > > effects of statins are reversed once use ceases. > > For many, but not all. Correct.
> > And, I am not aware of people being damaged within so short a time that had > > they been effectively monitored, *as recommended by health professionals and [quoted text clipped - 8 lines] > In reality most people just don't read these list's, they put their > trust in their doctor(s). And that's the fault of the pharmaceutical companies, and/or the vast number of doctors who do not commit malpractice, and/or the vast majority of people who do inform themselves, and/or the vast majority of people who can take statins and benefit from them without side effects?
> >>And to those that are damaged, who cares, certainly not the Doctors, > >>Pharmo's,....if the light is a bit bad for some of those professionals [quoted text clipped - 5 lines] > > I didn't say they don't care per se. Then what did you say?
> >>Zee is bringing informed (by experience) and documented information to > >>those contemplating taking this drug, and I hope she continues to do so. [quoted text clipped - 14 lines] > > > > Steve Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
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| Caploc | 13 Sep 2004 02:45 |
>>>>Steve >>>> [quoted text clipped - 26 lines] > > Who said that? You did. "Again, for every person who cannot tolerate statins, there are literally tens of thousands who can, do and benefit from statins."
So to rephrase: More people can tolerate statins, so stuff those that can't, simple really. Those that can tolerate statins don't have to worry, no need to mention them.
What I wrote was that publishing information that is skewed
> and biased in order to scare people off of something that will help the vast > majority of them is not servicing "the public's right to know." Actually Zee is helping to get the minority figures down.
>>Problem is as I see it, there is no back door, no way out, no fix once >>damaged, that's what makes taking this drug like a game of Russian > > Roulette. > > That is not so. Yes it is.
For many, if not most (I don't have exact numbers), side
> effects of statins are reversed once use ceases. For many, but not all.
> And, I am not aware of people being damaged within so short a time that had > they been effectively monitored, *as recommended by health professionals and [quoted text clipped - 5 lines] > the vast majority of drugs of all comes come with all of the above save only > the requirement for testing. In reality most people just don't read these list's, they put their trust in their doctor(s).
>>And to those that are damaged, who cares, certainly not the Doctors, >>Pharmo's,....if the light is a bit bad for some of those professionals >>maybe by removing their blinkers would allow them to see outside their >>consulting rooms and into the lounge rooms of those who have been damaged.
> This is highly inaccurate. I am not aware that doctors and people in the > pharmaceutical industries don't care. I didn't say they don't care per se.
>>Zee is bringing informed (by experience) and documented information to >>those contemplating taking this drug, and I hope she continues to do so. [quoted text clipped - 14 lines] > > Steve |
| Steve Marcus | 12 Sep 2004 12:59 |
> >>Steve > >> [quoted text clipped - 18 lines] > > So stuff those that can't..... eh Steve, majority rules and all that. Who said that? What I wrote was that publishing information that is skewed and biased in order to scare people off of something that will help the vast majority of them is not servicing "the public's right to know."
> Problem is as I see it, there is no back door, no way out, no fix once > damaged, that's what makes taking this drug like a game of Russian Roulette. That is not so. For many, if not most (I don't have exact numbers), side effects of statins are reversed once use ceases.
And, I am not aware of people being damaged within so short a time that had they been effectively monitored, *as recommended by health professionals and the pharmaceutical companies who make and sell statins*, they would not have suffered any damage at all. Every statin drug comes with a list of side effects, a list of contraindications, a list of drug interactions that are potentially harmful, a warning to report the side effects, and a statement that tests for monitoring potential harmful effects are necessary. Indeed, the vast majority of drugs of all comes come with all of the above save only the requirement for testing.
> And to those that are damaged, who cares, certainly not the Doctors, > Pharmo's,....if the light is a bit bad for some of those professionals > maybe by removing their blinkers would allow them to see outside their > consulting rooms and into the lounge rooms of those who have been damaged. This is highly inaccurate. I am not aware that doctors and people in the pharmaceutical industries don't care.
> Zee is bringing informed (by experience) and documented information to > those contemplating taking this drug, and I hope she continues to do so. She is bringing highly one sided and biased information to a forum where people are seeking help. Any competent physician will fully inform a patient of the potentially harmful side effects of any drug being prescribed. You cannot fill the prescription without receiving a rather lengthy written instruction and information paper that describes drug interactions and possible harmful effects. The problem, if there is one, is that people don't listen.
> Ahem, > Cappy > (Still trying to out run the death grip clutches of Statin therapy) Sure.
Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
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| Caploc | 12 Sep 2004 01:50 |
>>Steve >> [quoted text clipped - 16 lines] > > Steve So stuff those that can't..... eh Steve, majority rules and all that.
Problem is as I see it, there is no back door, no way out, no fix once damaged, that's what makes taking this drug like a game of Russian Roulette.
And to those that are damaged, who cares, certainly not the Doctors, Pharmo's,....if the light is a bit bad for some of those professionals maybe by removing their blinkers would allow them to see outside their consulting rooms and into the lounge rooms of those who have been damaged.
Zee is bringing informed (by experience) and documented information to those contemplating taking this drug, and I hope she continues to do so.
Ahem, Cappy (Still trying to out run the death grip clutches of Statin therapy)
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| Steve Marcus | 11 Sep 2004 22:56 |
> Steve > [quoted text clipped - 5 lines] > > Zee Indeed. Yet for every article that you post that casts medical professionals and/or the pharmaceutical industry in a bad light, there are at least a hundred that cast them in a good light. If you wish to facilitate the public's right to know, one would expect you to post a more balanced spectrum of information.
Again, for every person who cannot tolerate statins, there are literally tens of thousands who can, do and benefit from statins.
Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
<previous posts snipped; they are available via google.com
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| Zee | 11 Sep 2004 16:27 |
Steve
NIH, ICMJE, Cochrane Collaboration--all have said pharmas (with FDA collusion) have withheld vital (no pun intended) information from the public.
I believe in the public right to know.
Zee
http://jama.ama-assn.org/cgi/content/full/292.11.1359v1?etoc
"One consequence of this lack of reporting is a persistent bias in favor of positive results and therefore in favor of the newer and more expensive treatments. Another consequence is that harmful effects found in unpublished trials disappear without a trace, since the US Food and Drug Administration (FDA) has no mandate to report them to the public. The bad news about new drugs is disseminated later than the good news or not at all, resulting in widespread publication and outcome bias and in direct and widespread harm to patients.3-4"
>From an press release announcing this: http://jama.ama-assn.org/cgi/content/full/292.11.1363v1
International Committee of Medical Journal Editors Will Require Registration of Clinical Trials for Publication
"Honest reporting begins with revealing the existence of all clinical studies, even those that reflect unfavorably on a research sponsor's product. Unfortunately, selective reporting of trials does occur, and it distorts the body of evidence available for clinical decision making."
http://grants1.nih.gov/grants/guide/notice-files/NOT-OD-04-064.html
"NIH is proposing to make all NIH-funded research papers publicly available six months after their publication in journals. It wants all authors receiving NIH funding to send electronic copies of "final manuscripts" to NIH, which would make them freely available via PubMed six months after their official publication.
The agency is now seeking public comment on this proposal. As you might expect, for-profit publishers (as well as some putatively nonprofit scientific societies) are fighting it tooth and nail. It may help stiffen NIH's resolve if they hear from science writers who believe publicly funded research should be available to the public."
> > Exactly what I have done: > > [quoted text clipped - 25 lines] > represent the opinion of my employer, but is merely my personal > view. To reply, delete _spamout_ and replace with the numeral 3 |
| Steve Marcus | 11 Sep 2004 12:56 |
> Exactly what I have done: > [quoted text clipped - 4 lines] > > Zee You've also done this:
"Zee isn't posting about "recovering" from anything. She is posting about the negative impact she perceives to have been caused by a class of drugs that is used by millions of people without them being harmed."
And the problem with your claim that you do what is described in my earlier post (quoted in your post) is that you simultaneously denigrate medical professionals and pharmaceutical companies, doing your level best to render any advice that you (and others) might post that folks seek "professional opinions" to appear as a waste of time. One doesn't, after all, ask a dishonest stock broker which stock to buy.
Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
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| Zee | 10 Sep 2004 15:30 |
Exactly what I have done:
"...free to recommend that folks seek professional opinions, and become educated enough to question those opinions rationally,..."
Zee
> > George, > > [quoted text clipped - 58 lines] > > > Zee your point of view is so polluted by your obsession with statins > > > that it (your point of view) is meaningless. |
| Steve Marcus | 10 Sep 2004 12:40 |
> George, > [quoted text clipped - 4 lines] > have lost a child to a drunk driving murderer, because they are "polluted by > their obsession"? The proper analogy would be Christopher Reeve posting hundreds of posts about equestrian sports being too dangerous to be engaged in, and those who promote such sports not properly informing the public of those dangers. Zee isn't posting about "recovering" from anything. She is posting about the negative impact she perceives to have been caused by a class of drugs that is used by millions of people without them being harmed. Yes, just like horseback riding, the use of statins entails a very small degree of risk.
Your comments re MADD are even less apropriate. No rational person can argue that people should not drive drunk, or that those who do should not be subject to swift, immediate, and firm justice.
> What kind of politically incorrect prejudice permits you to disparage people > who have become disabled by a particular specific situation - STATIN ADVERSE [quoted text clipped - 5 lines] > about first-hand experience of being disabled by statin adverse effects > causes them to be less deserving of free speech, in your opinion? I detect no such bigotry in George's posts. Rather, I detect a great deal of bigotry with respect to medical professionals and the pharmaceutical industry, in Zee's posts, and in your posts. While she, and you, are free to post your opinions, others are just as free to point out the bias in your opinions. And certainly, others are free to recommend that folks seek professional opinions, and become educated enough to question those opinions rationally, rather than to rely upon posts such as those you routinely post and posts such as those Zee routinely posts.
> Your Bigotry against the handicapped is unbecoming. Your use of analogy, and accusations of bigotry, are totally erroneous and unwarranted, respectively.
Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
> > >Zee > > > > Zee your point of view is so polluted by your obsession with statins > > that it (your point of view) is meaningless. |
| Sharon Hope | 10 Sep 2004 06:12 |
George,
Would you say the same thing to Christopher Reeve about spinal paralysis? Is his interest in spinal nerve recovery "polluted by his obsession," because he has first-hand knowledged of that kind of disability? Do you similarly heckel and attack "mothers against drunk drivers" who happen to have lost a child to a drunk driving murderer, because they are "polluted by their obsession"?
What kind of politically incorrect prejudice permits you to disparage people who have become disabled by a particular specific situation - STATIN ADVERSE EFFECTS, simply for being advocates for 1) an effective treatment for themselves and others who were also similarly disabled, and 2) an effective means of screening so more people do not become disabled, or lacking that, at least forewarned awareness and informed consent? What about first-hand experience of being disabled by statin adverse effects causes them to be less deserving of free speech, in your opinion?
Your Bigotry against the handicapped is unbecoming.
> >Zee > > Zee your point of view is so polluted by your obsession with statins > that it (your point of view) is meaningless. |
| George | 09 Sep 2004 20:35 |
>Zee Zee your point of view is so polluted by your obsession with statins that it (your point of view) is meaningless.
Let anyone browsing this group do an author search under Zee or Fresh Horses and you will find some poor soul who posts 10's if not hundreds of posts a day every day all saying the same thing. Statins are bad. Well for you they were bad. For me they are fine.
Trouble is you might scare some poor soul into believing you are right and that in turn might cost them years of their life.
And yes I would rather trust my overworked doctor than you in a heartbeat.
Any lay person with time on their hands and no outside interests (in your case 24 hours a day it seems) can scour the internet and make a disinformation case against anything sound reasonable.
And since I am not gay, my GP (hunk?) works out a lot and has a backround in sports medicine which suits my particular needs just fine thank you.
How about get a life while you can and find another crusade. Ideally one where other people mught not suffer due to your obsession prone personality.
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| Zee | 09 Sep 2004 19:04 |
> Louise, with all due respect get your medical advice from your health > care professionals as opposed to Zee. Anyone can cut and paste > stufies to make any kind of arguement. > > Hopefully you have a doctor/s that can give you the care and advice > you need. George
With all due respect <g> Louise should become as informed as she can and take her questions and concerns to a physician. If I can respond to her requests for information with credible citations I will. I will also tell her of my experience, which may not be hers, and give her urls where she can read of others experiences. We all should survey and not rely on one poor over-worked family physician internist or cardiologist to do everything for us. That's the adult way. You on the other hand, at last post, were still taking one physician's advice because, I paraphrase, he's a hunk who works out a lot.
Zee
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| George | 09 Sep 2004 03:28 |
Louise, with all due respect get your medical advice from your health care professionals as opposed to Zee. Anyone can cut and paste stufies to make any kind of arguement.
Hopefully you have a doctor/s that can give you the care and advice you need.
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| Louise | 09 Sep 2004 02:19 |
> > Doctor piut me on Lipitor a few weeks ago, I developed side effects, > > diahrea, muscle aches, [quoted text clipped - 39 lines] > from an epidemiology group working out of the University of British > Columbia in Canada. They take no industry funding. And the same for Crestor? I just started it recently and I think it is giving me a great deal of stomach upset. However, I take a lot of medications and it's hard to isolate the factors involved.
Louise
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| Zee | 08 Sep 2004 23:29 |
> Doctor piut me on Lipitor a few weeks ago, I developed side effects, > diahrea, muscle aches, > He now wants me to take Pravachol, Are there any side effects to this > as well ? Salut Ted
Read here for the experiences of others who took pravachol:
http://www.askapatient.com/viewrating.asp?drug=19898&name=PRAVACHOL
http://medications.com/go/se/Pravachol
And here for a list of possible side effects:
http://www.rxlist.com/cgi/generic/pravast_ad.htm
In my own experience with pravachol, yes, it can cause similar symptoms to lipitor. I know of many who had to stop taking it because of marked side effects. However there is at least one poster on this newsgroup who says he takes it with no difficulty.
In my opinion if you have had side effects to one, you will likely have side effects from all. Only you can determine if the side effects are worth it.
Do not be lulled into thinking liver enzyme tests will detect all statin induced myopathy. You can have muscle pain and normal liver tests.
Statins deplete coenzyme q10. This has been proven. It has not been proven however that taking coq10 orally will replenish the body's supply. Former US astronaut Duane Graveline took lipitor and suffered memory loss, transient global amnesia and other cognitive problems. So did thousands of others including me. On Graveline's website and in his book he discusses what coenzyme q10 depletion does to the body and brain.
http://www.spacedoc.net
These sites have helpful information about statins. The latter two are from an epidemiology group working out of the University of British Columbia in Canada. They take no industry funding.
http://www.medicalconsumers.org http://www.medicationsense.com/ http://www.ti.ubc.ca/pages/letter48.htm http://www.ti.ubc.ca/pages/letter49.htm
Do all the research you can and make an informed decision. Google is a great resource.
Zee
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| Ted | 08 Sep 2004 22:52 |
Doctor piut me on Lipitor a few weeks ago, I developed side effects, diahrea, muscle aches, He now wants me to take Pravachol, Are there any side effects to this as well ?
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