Re: Pravachol verses Lipitor ?
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Re: Pravachol verses Lipitor ?
| Steve Marcus | 12 Sep 2004 13:19 |
> > > Steve > > > [quoted text clipped - 20 lines] > > LOL. I am under no obligation to represent pharma. You claimed to be using this forum to satisfy the public's right to know. That knowledge includes the good, as well as the bad, about the pharmaceutical industry.
> They are well looked > after by those denizens of Goebbel's profession whom they employ. Your bias is showing. The public's right to know should be from balanced sources, not from biased sources. Otherwise, you have become what you are claiming to contradict.
> I am > in most instances responding to query from those who have already > crossed over that thin line. You would have absolutely no way of knowing that without examining them, having complete medical histories from them, and being a qualified health care professional.
> They are experiencing symptoms that might > be attributed to statins. Or might not.
> No-one apparently has told them. Before or after the fact of their symptoms?
> They have > not done their homework, granted. (No point rubbing their faces in it > here Steve). That's the *whole* point, Zee. A while back I posted something about the inherent stupidity of someone coming to this newsgroup and asking for medical advice. It is equally stupid to not have asked questions when the medication was being prescribed, and/or to not have read the material that, by law, comes with the medication.
Your brief is to scare away the 99.03% of people who will be able to take a statin drug without side effects because of the remaining .07%, some fraction of them will have not been properly informed of the side effects, the contraindications, the drug interactions, and the need for testing to monitor for those side effects. That failure to inform on the part of the doctor would be malpractice, the failure to inform oneself (or at least ask the questions) is their own failure. The failure to be properly diagnosed when suffering what could be a statin induced side effect (as, for example, detailed above by Cappy), is again medical malpractice.
> And if statins work the way it is said they do, that may > be damage that is not recoverable. (Is MS or AlS damage 'recoverable?') [quoted text clipped - 6 lines] > tolerating for the sake of risk/benefit may not be very wise in light > of rhabdomyolysis. Bang it's there. Too late. From your typical posts, no one would take away the information that you people should take them if they need to. Apparently, there is some balance in your point of view that has come out now that you've responded to this series of posts.
> If people can tolerate them and benefit and *truly* need them then well > and good. Why is it a problem that I provide another side of the story > with which to weigh a decision? You have it. Obviously the person > posting here saying "could?" does not. It is a problem because you typically present only one side, the side that is relevent for less than .1% of those who take statins. As noted above, this is the first post from you that I can recall you stating that people who need statins should take them.
> I have no problem with anyone using statins. I have a problem with > suppression of information. Deliberate suppression. But the suppression of information is in your imagination. Neither doctors nor the pharmaceutical industries suppress the drug interactions, the contraindications, the potential side effects and the need for constant blood tests to monitor various functions when taking statins. Unless you consider malpractice on the part of the prescribing doctor to be "suppression" of information.
> And as you must > acknowledge Steve I am not alone in thinking that is wrong, must and [quoted text clipped - 5 lines] > I didn't write Rennie's editorial. I just posted it. Those damning > words are his. Your failure to appreciate that he has at least as big an axe to grind as the one that you imagine is wielded by the pharmaceutical is part of the problem.
> Zee Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
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| Zee | 11 Sep 2004 23:40 |
> > Steve > > [quoted text clipped - 14 lines] > Again, for every person who cannot tolerate statins, there are literally > tens of thousands who can, do and benefit from statins. LOL. I am under no obligation to represent pharma. They are well looked after by those denizens of Goebbel's profession whom they employ. I am in most instances responding to query from those who have already crossed over that thin line. They are experiencing symptoms that might be attributed to statins. No-one apparently has told them. They have not done their homework, granted. (No point rubbing their faces in it here Steve). And if statins work the way it is said they do, that may be damage that is not recoverable. (Is MS or AlS damage 'recoverable?') That is why it is so important not to take them if you don't need to; to take as little a dose as possible if you do (varying per individual need of course) and to use them for as short a time as possible. Yes take all this information, and whatever else you find, and go talk to your doctor. And if he or she won't find another. Know that the liver enzyme tests aren't going to do it, know that ignoring the symptoms and tolerating for the sake of risk/benefit may not be very wise in light of rhabdomyolysis. Bang it's there. Too late.
If people can tolerate them and benefit and *truly* need them then well and good. Why is it a problem that I provide another side of the story with which to weigh a decision? You have it. Obviously the person posting here saying "could?" does not.
I have no problem with anyone using statins. I have a problem with suppression of information. Deliberate suppression. And as you must acknowledge Steve I am not alone in thinking that is wrong, must and will change. Then, I think, there will be fewer problem drugs like statins. Who is to say what difficuties and harm might have been avoided if the runaway train that is the pharmaceutical business had been throttled back or controlled some time go, as is being done now.
I didn't write Rennie's editorial. I just posted it. Those damning words are his.
Zee
> Steve > -- [quoted text clipped - 5 lines] > > > <previous posts snipped; they are available via google.com |
| Steve Marcus | 11 Sep 2004 22:56 |
> Steve > [quoted text clipped - 5 lines] > > Zee Indeed. Yet for every article that you post that casts medical professionals and/or the pharmaceutical industry in a bad light, there are at least a hundred that cast them in a good light. If you wish to facilitate the public's right to know, one would expect you to post a more balanced spectrum of information.
Again, for every person who cannot tolerate statins, there are literally tens of thousands who can, do and benefit from statins.
Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
<previous posts snipped; they are available via google.com
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| Zee | 11 Sep 2004 16:27 |
Steve
NIH, ICMJE, Cochrane Collaboration--all have said pharmas (with FDA collusion) have withheld vital (no pun intended) information from the public.
I believe in the public right to know.
Zee
http://jama.ama-assn.org/cgi/content/full/292.11.1359v1?etoc
"One consequence of this lack of reporting is a persistent bias in favor of positive results and therefore in favor of the newer and more expensive treatments. Another consequence is that harmful effects found in unpublished trials disappear without a trace, since the US Food and Drug Administration (FDA) has no mandate to report them to the public. The bad news about new drugs is disseminated later than the good news or not at all, resulting in widespread publication and outcome bias and in direct and widespread harm to patients.3-4"
>From an press release announcing this: http://jama.ama-assn.org/cgi/content/full/292.11.1363v1
International Committee of Medical Journal Editors Will Require Registration of Clinical Trials for Publication
"Honest reporting begins with revealing the existence of all clinical studies, even those that reflect unfavorably on a research sponsor's product. Unfortunately, selective reporting of trials does occur, and it distorts the body of evidence available for clinical decision making."
http://grants1.nih.gov/grants/guide/notice-files/NOT-OD-04-064.html
"NIH is proposing to make all NIH-funded research papers publicly available six months after their publication in journals. It wants all authors receiving NIH funding to send electronic copies of "final manuscripts" to NIH, which would make them freely available via PubMed six months after their official publication.
The agency is now seeking public comment on this proposal. As you might expect, for-profit publishers (as well as some putatively nonprofit scientific societies) are fighting it tooth and nail. It may help stiffen NIH's resolve if they hear from science writers who believe publicly funded research should be available to the public."
> > Exactly what I have done: > > [quoted text clipped - 25 lines] > represent the opinion of my employer, but is merely my personal > view. To reply, delete _spamout_ and replace with the numeral 3 |
| Steve Marcus | 11 Sep 2004 12:56 |
> Exactly what I have done: > [quoted text clipped - 4 lines] > > Zee You've also done this:
"Zee isn't posting about "recovering" from anything. She is posting about the negative impact she perceives to have been caused by a class of drugs that is used by millions of people without them being harmed."
And the problem with your claim that you do what is described in my earlier post (quoted in your post) is that you simultaneously denigrate medical professionals and pharmaceutical companies, doing your level best to render any advice that you (and others) might post that folks seek "professional opinions" to appear as a waste of time. One doesn't, after all, ask a dishonest stock broker which stock to buy.
Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
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| Zee | 10 Sep 2004 15:30 |
Exactly what I have done:
"...free to recommend that folks seek professional opinions, and become educated enough to question those opinions rationally,..."
Zee
> > George, > > [quoted text clipped - 58 lines] > > > Zee your point of view is so polluted by your obsession with statins > > > that it (your point of view) is meaningless. |
| Steve Marcus | 10 Sep 2004 12:40 |
> George, > [quoted text clipped - 4 lines] > have lost a child to a drunk driving murderer, because they are "polluted by > their obsession"? The proper analogy would be Christopher Reeve posting hundreds of posts about equestrian sports being too dangerous to be engaged in, and those who promote such sports not properly informing the public of those dangers. Zee isn't posting about "recovering" from anything. She is posting about the negative impact she perceives to have been caused by a class of drugs that is used by millions of people without them being harmed. Yes, just like horseback riding, the use of statins entails a very small degree of risk.
Your comments re MADD are even less apropriate. No rational person can argue that people should not drive drunk, or that those who do should not be subject to swift, immediate, and firm justice.
> What kind of politically incorrect prejudice permits you to disparage people > who have become disabled by a particular specific situation - STATIN ADVERSE [quoted text clipped - 5 lines] > about first-hand experience of being disabled by statin adverse effects > causes them to be less deserving of free speech, in your opinion? I detect no such bigotry in George's posts. Rather, I detect a great deal of bigotry with respect to medical professionals and the pharmaceutical industry, in Zee's posts, and in your posts. While she, and you, are free to post your opinions, others are just as free to point out the bias in your opinions. And certainly, others are free to recommend that folks seek professional opinions, and become educated enough to question those opinions rationally, rather than to rely upon posts such as those you routinely post and posts such as those Zee routinely posts.
> Your Bigotry against the handicapped is unbecoming. Your use of analogy, and accusations of bigotry, are totally erroneous and unwarranted, respectively.
Steve
 Signature The above posting is neither a legal opinion nor legal advice, because we do not have an attorney-client relationship, and should not be construed as either. This posting does not represent the opinion of my employer, but is merely my personal view. To reply, delete _spamout_ and replace with the numeral 3
> > >Zee > > > > Zee your point of view is so polluted by your obsession with statins > > that it (your point of view) is meaningless. |
| Sharon Hope | 10 Sep 2004 06:12 |
George,
Would you say the same thing to Christopher Reeve about spinal paralysis? Is his interest in spinal nerve recovery "polluted by his obsession," because he has first-hand knowledged of that kind of disability? Do you similarly heckel and attack "mothers against drunk drivers" who happen to have lost a child to a drunk driving murderer, because they are "polluted by their obsession"?
What kind of politically incorrect prejudice permits you to disparage people who have become disabled by a particular specific situation - STATIN ADVERSE EFFECTS, simply for being advocates for 1) an effective treatment for themselves and others who were also similarly disabled, and 2) an effective means of screening so more people do not become disabled, or lacking that, at least forewarned awareness and informed consent? What about first-hand experience of being disabled by statin adverse effects causes them to be less deserving of free speech, in your opinion?
Your Bigotry against the handicapped is unbecoming.
> >Zee > > Zee your point of view is so polluted by your obsession with statins > that it (your point of view) is meaningless. |
| George | 09 Sep 2004 20:35 |
>Zee Zee your point of view is so polluted by your obsession with statins that it (your point of view) is meaningless.
Let anyone browsing this group do an author search under Zee or Fresh Horses and you will find some poor soul who posts 10's if not hundreds of posts a day every day all saying the same thing. Statins are bad. Well for you they were bad. For me they are fine.
Trouble is you might scare some poor soul into believing you are right and that in turn might cost them years of their life.
And yes I would rather trust my overworked doctor than you in a heartbeat.
Any lay person with time on their hands and no outside interests (in your case 24 hours a day it seems) can scour the internet and make a disinformation case against anything sound reasonable.
And since I am not gay, my GP (hunk?) works out a lot and has a backround in sports medicine which suits my particular needs just fine thank you.
How about get a life while you can and find another crusade. Ideally one where other people mught not suffer due to your obsession prone personality.
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| Zee | 09 Sep 2004 19:04 |
> Louise, with all due respect get your medical advice from your health > care professionals as opposed to Zee. Anyone can cut and paste > stufies to make any kind of arguement. > > Hopefully you have a doctor/s that can give you the care and advice > you need. George
With all due respect <g> Louise should become as informed as she can and take her questions and concerns to a physician. If I can respond to her requests for information with credible citations I will. I will also tell her of my experience, which may not be hers, and give her urls where she can read of others experiences. We all should survey and not rely on one poor over-worked family physician internist or cardiologist to do everything for us. That's the adult way. You on the other hand, at last post, were still taking one physician's advice because, I paraphrase, he's a hunk who works out a lot.
Zee
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| George | 09 Sep 2004 03:28 |
Louise, with all due respect get your medical advice from your health care professionals as opposed to Zee. Anyone can cut and paste stufies to make any kind of arguement.
Hopefully you have a doctor/s that can give you the care and advice you need.
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| Louise | 09 Sep 2004 02:19 |
> > Doctor piut me on Lipitor a few weeks ago, I developed side effects, > > diahrea, muscle aches, [quoted text clipped - 39 lines] > from an epidemiology group working out of the University of British > Columbia in Canada. They take no industry funding. And the same for Crestor? I just started it recently and I think it is giving me a great deal of stomach upset. However, I take a lot of medications and it's hard to isolate the factors involved.
Louise
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| Zee | 08 Sep 2004 23:29 |
> Doctor piut me on Lipitor a few weeks ago, I developed side effects, > diahrea, muscle aches, > He now wants me to take Pravachol, Are there any side effects to this > as well ? Salut Ted
Read here for the experiences of others who took pravachol:
http://www.askapatient.com/viewrating.asp?drug=19898&name=PRAVACHOL
http://medications.com/go/se/Pravachol
And here for a list of possible side effects:
http://www.rxlist.com/cgi/generic/pravast_ad.htm
In my own experience with pravachol, yes, it can cause similar symptoms to lipitor. I know of many who had to stop taking it because of marked side effects. However there is at least one poster on this newsgroup who says he takes it with no difficulty.
In my opinion if you have had side effects to one, you will likely have side effects from all. Only you can determine if the side effects are worth it.
Do not be lulled into thinking liver enzyme tests will detect all statin induced myopathy. You can have muscle pain and normal liver tests.
Statins deplete coenzyme q10. This has been proven. It has not been proven however that taking coq10 orally will replenish the body's supply. Former US astronaut Duane Graveline took lipitor and suffered memory loss, transient global amnesia and other cognitive problems. So did thousands of others including me. On Graveline's website and in his book he discusses what coenzyme q10 depletion does to the body and brain.
http://www.spacedoc.net
These sites have helpful information about statins. The latter two are from an epidemiology group working out of the University of British Columbia in Canada. They take no industry funding.
http://www.medicalconsumers.org http://www.medicationsense.com/ http://www.ti.ubc.ca/pages/letter48.htm http://www.ti.ubc.ca/pages/letter49.htm
Do all the research you can and make an informed decision. Google is a great resource.
Zee
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| Ted | 08 Sep 2004 22:52 |
Doctor piut me on Lipitor a few weeks ago, I developed side effects, diahrea, muscle aches, He now wants me to take Pravachol, Are there any side effects to this as well ?
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