RPE change question, pls help

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Dave - 24 Mar 2004 23:10 GMT

I have been searching for days on the web about RPE changes but can't seem
to find anything.
Please, please, can anyone here help with information or internet links.

After eye symptoms coming on rather abruptly I went to an opthamologist who
found a little mottled RPE spec in the central macula. It was not there in
my last visit not too long ago. I had a Flourscein angiography that did not
showing anything else other than the mottled spec.

My eyesight is still good with my glasses but I have trouble focusing and
straight lines seem to not always be fixed. This is causing me to feel sea
sick and dizzy like I am on rough seas. It is also more difficult to read or
use the computer like it was only a few weeks ago. It is making me nuts and
hope my brain or eyes whatever will adjust as this is very disturbing living
like this.

How long does it take for RPE mottling to appear from light damage or injury
to the eye?

Is there anyway to return the pigment to normal or where it is usable? Are
there supplements, clinical trials, etc, or anything on the horizon?

Anyone have any good links on this.

Thx.

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Dr. Leukoma - 25 Mar 2004 02:37 GMT

> I have been searching for days on the web about RPE changes but can't
> seem to find anything.
[quoted text clipped - 24 lines]
>
> Thx.

If straight lines seem curved, then there is some elevation of the macula.
It could be that you have something called central serous retinopathy.
This condition caues diffuse leakage beneath the central retina, is
typically self-limiting, and results in metamorphopsia(distortion of shape)
and slight loss of acuity. In some people is is recurrent, and can result
in permanent pigmentary changes. However, this would indeed show up on a
fluorescein angiogram.

Pigmentary mottling in the macula is not always indicative of a disease
process, and it does not always herald a disturbance in vision. One thing
is for sure, and that is that pigmentary changes are not reversible.

DrG

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Dave - 25 Mar 2004 04:52 GMT

> If straight lines seem curved, then there is some elevation of the macula.
> It could be that you have something called central serous retinopathy.
[quoted text clipped - 9 lines]
>
> DrG

Thanks for the response. Any idea how it takes for the pigment to change
lets say from light damage or injury?

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Dave - 26 Mar 2004 20:51 GMT

> > I have been searching for days on the web about RPE changes but can't
> > seem to find anything.
[quoted text clipped - 38 lines]
>
> DrG

I received the report back for the FA that says mild window defect type
starting at area of RPE change, no edema. What is a window defect? Does
the window defect close up so there is only RPE. Perhaps it is the window
defect that is causing the curved lines.

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