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Medical Forum / General / Vision / February 2009

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I got Giant Papillary Conjunctivitis!

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Pia - 27 Feb 2009 14:09 GMT
Hi,

I went to see an optometrist to get measurements for any
possible base curve changes after I lost one of my RGP lens
last week. She suddenly inverted my eyelid and saw a mild GPC
in my left eye. I don't know where it came from. I used RGP
for 20 years. After I lost the RGP lens last week. I started
trial lens of Focus Monthly 3 days ago. Now could my
GPC be from the thimerosal inthe solutions I used for
the Focus Monthly? If I'm allergic to thimerosal, could it
cause a GPC in just one use (I only used the Focus Monthly
twice) soaked in a thimerosal solution. The GPC
seems to be at the center of the eyelid and has a
whitist center. I heard the RGP couldn't cause
this as it is mostly at edge of eyelid inflicted by the edge of
the RGP lens and a center location is mostly caused by
soft contacts which I haven't used more than 20 years.
I just started Focus Monthly 3 days ago. So could my
GPC be caused by the thimerosal just 2 days ago?
You know Immune reactions are fast and can develope
within 24 hours so I can't eliminate the possibility.

I need to know what could have caused my GPR because
my present soft contact solution has thimerosal and won't
use the soft lens if it is the culprit. Do all people who have
GPC intolerant to thimerosal such that they can't use it?
Would it get the GPC worse? Last night. I got a trial lens
of the Ciba O2Optik Silicone Hydrogel soft contact and use
it for 2 hours. I heard that a Silicone Hydrogel is stiffer
hence has more tendency for GPC.

So which has more tendency to cause GPC. RGP lens
or Silicone Hydrogel soft contact?  What soft contact
solutions don't contain thimerosal??

Also are daily disposable Focus Dailies for example soaked
in a thimerosal solution?

Thanks.

Pia
Mike Tyner - 27 Feb 2009 16:23 GMT
> trial lens of Focus Monthly 3 days ago. Now could my
> GPC be from the thimerosal inthe solutions I used for
> the Focus Monthly? If I'm allergic to thimerosal, could it
> cause a GPC in just one use (I only used the Focus Monthly
> twice) soaked in a thimerosal solution.

Why on earth would you use a thimerosal solution?

> I just started Focus Monthly 3 days ago. So could my
> GPC be caused by the thimerosal just 2 days ago?

Not the thimerosal.

> You know Immune reactions are fast and can develope
> within 24 hours so I can't eliminate the possibility.

Thimerosal reactions are fast. GPC is not.

> I need to know what could have caused my GPR because
> my present soft contact solution has thimerosal and won't
> use the soft lens if it is the culprit. Do all people who have
> GPC intolerant to thimerosal such that they can't use it?

You need to see a few thimerosal reactions. Big, swollen, puffy eyes. You
don't have that.

> it for 2 hours. I heard that a Silicone Hydrogel is stiffer
> hence has more tendency for GPC.

Some SiHy materials are stiffer. Others are not.

> So which has more tendency to cause GPC. RGP lens
> or Silicone Hydrogel soft contact?

It's not common with either one.

> What soft contact
> solutions don't contain thimerosal??

In the US, none of them AFAIK.

If you want better disinfection with less chance of problems, ask your
doctor about a peroxide disinfection system like ClearCare.

> Also are daily disposable Focus Dailies for example soaked
> in a thimerosal solution?

No contacts in the US are packaged with thimerosal.

Thimerosal does not cause GPC.

-MT
Mike Tyner - 27 Feb 2009 18:43 GMT
> In the US, none of them AFAIK.

Should be "In the US, none of the major brands contain thimerosal".

-MT
Pia - 27 Feb 2009 22:42 GMT
> > trial lens of Focus Monthly 3 days ago. Now could my
> > GPC be from the thimerosal inthe solutions I used for
[quoted text clipped - 48 lines]
>
> -MT

But according to web sites. Thimerosal can cause some immune
reactions which can later form GPC. How can you say it doesn't
cause GPC when one of the strong candidate for forming GPC
is immune response to thimerosal.

Thanks.

Pia
Mike Tyner - 27 Feb 2009 23:05 GMT
> But according to web sites. Thimerosal can cause some immune
> reactions which can later form GPC. How can you say it doesn't
> cause GPC when one of the strong candidate for forming GPC
> is immune response to thimerosal.

That's news to me. Seems I recall thimerosal was also a "strong candidate"
for causing autism. How's that working out?

I quit using thimerosal solutions about 20 years ago. GPC didn't go away
until people started replacing soft lenses regularly.

Now it's unusual to see GPC. It still crops up now and then, even with RGP
lenses. But there's no thimerosal around to cause it.

The idea that using thimerosal for a couple of days could suddenly bring on
GPC, well, that's a stretch of the imagination.

-MT
Pia - 28 Feb 2009 00:05 GMT
> > But according to web sites. Thimerosal can cause some immune
> > reactions which can later form GPC. How can you say it doesn't
[quoted text clipped - 14 lines]
>
> -MT

Maybe protein deposits and thimerosal are some of the factors
in contributing to GPC. Say. Can you please reply the thread
Large Diameter RGP lens because I have to make an important
decision asap. My doctor is waiting for my confirmation to
order the 10mm or 9.5mm as she said I can choose. I told her
that larger RGP can have problems with tear exchange. She
said if that is the case, then all soft contacts with 14mm diameter
can't get the debris out as it is larger than the RGP 10mm. I
don't want problem with tear exchange now that I can mild
GPC.

Pia
Mike Tyner - 28 Feb 2009 01:02 GMT
> in contributing to GPC. Say. Can you please reply the thread
> Large Diameter RGP lens because I have to make an important
> decision asap. My doctor is waiting for my confirmation to
> order the 10mm or 9.5mm as she said I can choose. I told her
> that larger RGP can have problems with tear exchange.

I really don't have much of an opinion.

9.5 is already pretty large.

It's easy to create tear exchange problems with very small lenses, if you
wanted to. I don't find it hard to avoid those problems when making lenses a
half-millimeter larger.

I'm not looking at your eyes through a microscope. She was. If she
recommended 10.0 I'd clam up and take her recommendation.

No point trying to become an expert when you're already paying one to decide
for you.

-MT
Pia - 28 Feb 2009 12:18 GMT
> > in contributing to GPC. Say. Can you please reply the thread
> > Large Diameter RGP lens because I have to make an important
[quoted text clipped - 17 lines]
>
> -MT

Guess what. I visited an opthalmologist and after thorough
examination.
He said the white spot is just a concretion or mineral deposit. It's
not
bacterial at all! Not only that. I went to another optometrist. After
thorough analysis. He said my eyes can only take contact lens
of size 9mm. 10mm is too large for me. So the first optometrist
being young is simply inexperience. So it won't hurt to consult many
eye doctors before getting a decision. Now I'll find a third
optometrist
although I think 9mm is optimal because i've been using 9mm for
20 years without problem.

Pia
Mike Tyner - 28 Feb 2009 13:07 GMT
> Guess what. I visited an opthalmologist and after thorough
> examination. He said the white spot is just a concretion or
> mineral deposit. It's not bacterial at all!

I must have missed something. I didn't know you said anything about
bacteria.

> Not only that. I went to another optometrist. After
> thorough analysis. He said my eyes can only take contact lens
> of size 9mm. 10mm is too large for me.

Most GP contacts are made less than 10 mm.

> So the first optometrist being young is simply inexperience.

Another sign of inexperience is asking you to choose the diameter. Either
inexperience, or frustration.

> So it won't hurt to consult many eye doctors

Asking three different doctors is a good way to get three different answers.
Then you can pick whatever answer you want.

> although I think 9mm is optimal because i've been using 9mm
> for 20 years without problem.

There.. you have your answer.

-MT
Neil Brooks - 28 Feb 2009 15:30 GMT
> > Guess what. I visited an opthalmologist and after thorough
> > examination. He said the white spot is just a concretion or
[quoted text clipped - 25 lines]
>
> -MT

Mike,

Sometimes, over the internet it the ONLY way to treat patients ;-)
 
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