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Medical Forum / General / Vision / July 2007

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Heredity and Colorblindness

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JoeNeedsToAcceptCC - 29 Jun 2007 17:26 GMT
My maternal grandfather is colorblind, my mother is colorblind, I'm
colorblind, but my brother is not.  My father is also not colorblind.
I don't know of anyone colorblind on my dad's side.  One of my friends
told me that in some science class they discussed heredity and found
out that if your mom is colorblind you are definitely color-blind.
But my brother is not color-blind.  Is one of us adopted, or does that
teacher need some more lessons themselves?

Regards,
Joe (from MN)
Kisame Hoshigaki - 29 Jun 2007 17:33 GMT
> My maternal grandfather is colorblind, my mother is colorblind, I'm
> colorblind, but my brother is not.  My father is also not colorblind.
[quoted text clipped - 6 lines]
> Regards,
> Joe (from MN)

Ha!

The funny thing is I had a biology lesson about this in school just
yesterday. I think it has something to do with recessive and dominant
genes; If your mother had the dominant gene, but your father had the
recessive form, and you end up with the dominant form, then you will
be colour blind. Likewise if you brother ended up with two pairs of
the recessive form, then he wouldn't be colour blind.

Well, I think that's how it works anyway!

-KH
p.clarkii@gmail.com - 30 Jun 2007 05:12 GMT
On Jun 29, 12:33 pm, Kisame Hoshigaki
<absolutelyinvinci...@hotmail.com> wrote:

> > My maternal grandfather is colorblind, my mother is colorblind, I'm
> > colorblind, but my brother is not.  My father is also not colorblind.
[quoted text clipped - 19 lines]
>
> -KH

guess you didn't pay attention in class Revival (or Zetsu, or whatever
the name-of-the-day is).
colorblindness is X-linked.  if a mother has it, then there is
virtually no way one son can have it and the other son can't.  do you
understand the concept of sex-linked traits?  do you know how many X
chromosomes males and females have?  do you know how many affected X
chromosomes a color-blind woman has?

i know, why not make up a different name and post tomorrow as a
genetics expert who claims to know everything on this topic?
yesterday you already posted twice under two different names to some
guy who asked about the visual effects of prozac and you tried to act
like you really were an expert on the subject.

tell me, which do you like better in your internet forum role playing
games-- the role of the naive 12 year old student, or the expert
authoritative adult?

did you ever play dolls as a child?  has anyone ever suggested you get
professional counseling?
Kisame Hoshigaki - 30 Jun 2007 11:10 GMT
pclar,

>guess you didn't pay attention in class Revival (or Zetsu, or whatever
>the name-of-the-day is).
[quoted text clipped - 3 lines]
>chromosomes males and females have?  do you know how many affected X
>chromosomes a color-blind woman has?

Yes admittedly, I wasn't really paying much attention in that lesson
-- And yesterday was the first time I even heard about genes and
alleles and so forth, so exc-*Use* me if I'm not suddenly an expert in
that field! You don't have to go berserk, man.

>tell me, which do you like better in your internet forum role playing
>games-- the role of the naive 12 year old student, or the expert
>authoritative adult?

Actually I am 15 years old.

>some guy who asked about the visual effects of prozac and you
>tried to act like you really were an expert on the subject.

No, I didn't. I just happened to know a little bit about the effects
of Prozac -- I wasn't trying to act like an expert on the subject.
Anyway, that's why I wrote 'but check with your eye doc' at the end.
Jeeze!
JoeNeedsToAcceptCC - 02 Jul 2007 15:17 GMT
Thanks everyone for the postings, but I still don't seem to know the
answer to this question.  I'll ask my eye doctor (which was suggested
by a 15-year-old and is probably the best answer here!)
Mike Tyner - 02 Jul 2007 15:31 GMT
> Thanks everyone for the postings, but I still don't seem to know the
> answer to this question.  I'll ask my eye doctor (which was suggested
> by a 15-year-old and is probably the best answer here!)

I don't think he'll know whether you're adopted or not. There are too many
varieties and degrees of "colorblindness" to draw that conclusion without
lots more information.

-MT
Salmon Egg - 02 Jul 2007 19:33 GMT
On 7/2/07 7:31 AM, in article l4udnaZP58jHkRTbnZ2dnUVZ_ternZ2d@giganews.com,

> I don't think he'll know whether you're adopted or not. There are too many
> varieties and degrees of "colorblindness" to draw that conclusion without
> lots more information.

What are the most common, although probably rare, types of colorblindness
that are not X linked? Even so, what kind of colorblindness of a mother
could possibly not show up in a son?

Bill
-- Support the troops. Impeach Bush. Oh, I forgot about Cheney.
Mike Tyner - 02 Jul 2007 20:09 GMT
> What are the most common, although probably rare, types of colorblindness
> that are not X linked? Even so, what kind of colorblindness of a mother
> could possibly not show up in a son?

From the example, it could be autosomal dominant. If it's the typical XLR,
there has to be another line of inheritance we don't know about. Also
clouding the question are variable expression, incomplete penetrance, and
mosaicism.

I'm just not ready to say his brother is adopted.

-MT
Salmon Egg - 03 Jul 2007 06:08 GMT
On 7/2/07 12:09 PM, in article
9M6dnXUA9OXt0BTbnZ2dnUVZ_jqdnZ2d@giganews.com, "Mike Tyner"
<mtyner@mindspring.com> wrote:

> From the example, it could be autosomal dominant. If it's the typical XLR,
> there has to be another line of inheritance we don't know about. Also
> clouding the question are variable expression, incomplete penetrance, and
> mosaicism.

Are you saying that there are some dominant autosomes that will overcome
ordinary color defective X chromosomes? That sounds mighty far fetched.

Similarly, it is very difficult for me to believe that there would be a
defective X mutation producing a mosaic X without the defect.

My guess of a brother that is an XX with some defect in sexual development
(excessive testosterone for example), far fetched as it is, is less far
fetched than a mosaic mutation that corrects a gene defect.

An adoptive brother seems the most likely possibility so far. A DNA test
ought to establish kinship.

Bill
Signature

Iraq: About three Virginia Techs a month

p.clarkii@gmail.com - 04 Jul 2007 06:21 GMT
> My guess of a brother that is an XX ...

???
p.clarkii@gmail.com - 03 Jul 2007 01:56 GMT
> Thanks everyone for the postings, but I still don't seem to know the
> answer to this question.  I'll ask my eye doctor (which was suggested
> by a 15-year-old and is probably the best answer here!)

hi Revival
Mike Tyner - 29 Jun 2007 17:53 GMT
> My maternal grandfather is colorblind, my mother is colorblind, I'm
> colorblind, but my brother is not.  My father is also not colorblind.

Most "colorblindness" is inherited as X-linked recessive, but there are
several variations, and no reason two independent genetic problems can't
exist in the same family.

Yours may not be the typical x-linked recessive pattern. It isn't unusual
for real-life bloodlines to deviate from the simple rules you learn at
first.

-MT
Kisame Hoshigaki - 29 Jun 2007 18:02 GMT
> > My maternal grandfather is colorblind, my mother is colorblind, I'm
> > colorblind, but my brother is not.  My father is also not colorblind.
[quoted text clipped - 8 lines]
>
> -MT

Mike, is it possible to acquire colourblindness?

My grandfather became colourblind recently, which he wasn't before.
Neil Brooks - 29 Jun 2007 18:09 GMT
On Jun 29, 10:02 am, Kisame Hoshigaki
<absolutelyinvinci...@hotmail.com> wrote:

> > > My maternal grandfather is colorblind, my mother is colorblind, I'm
> > > colorblind, but my brother is not.  My father is also not colorblind.
[quoted text clipped - 12 lines]
>
> My grandfather became colourblind recently, which he wasn't before.

Mike,

Please recall the sage words of this very same poster:

[quote]
Dear Mike,

I don't understand: What does this squabbling accomplish?

We have established that Otis refuses to answer valid questions: Yes.

We have established that Otis refuses to leave this newsgroup: Yes.

But why continue this same argument year after year after year?

How does it benefit this newsgroup?
[/quote]
Kisame Hoshigaki - 29 Jun 2007 18:15 GMT
> On Jun 29, 10:02 am, Kisame Hoshigaki
>
[quoted text clipped - 34 lines]
> How does it benefit this newsgroup?
> [/quote]

Mike seems like a wise man; all I did was ask him a question!
Mike Tyner - 29 Jun 2007 18:19 GMT
> Mike, is it possible to acquire colourblindness?
>
> My grandfather became colourblind recently, which he wasn't before.

It won't be the same as genetic colorblindness.

In grandfathers, it's usually cataract that causes color distortion.

In grandmothers, it causes them to dye their hair blue.

-MT
Kisame Hoshigaki - 29 Jun 2007 18:32 GMT
> > Mike, is it possible to acquire colourblindness?
>
[quoted text clipped - 7 lines]
>
> -MT

Oh, I understand now. Thank you, Mike!

In fact, my grandfather has perfectly normal vision, apart from the
colourblindness -- so I guess he must have inherited it.

--

>color

I have always found it funny how Americans spell colour as color LOL.
It's so confusing!
Kisame Hoshigaki - 29 Jun 2007 18:34 GMT
Oh, I understand now. Thank you, Mike!

In fact, my grandfather has perfectly normal vision, apart from the
colourblindness -- so I guess he must have inherited it.

Off-topic: I have always found it funny how Americans spell colour as
color LOL. It's so confusing!

-KH
Mike Tyner - 29 Jun 2007 22:49 GMT
> Oh, I understand now. Thank you, Mike!
>
> In fact, my grandfather has perfectly normal vision, apart from the
> colourblindness -- so I guess he must have inherited it.

No. Ordinary colorblindness (the genetic kind) isn't acquired. It's there
from birth or it isn't there. Your granddad got nuclear sclerosis.

> Off-topic: I have always found it funny how Americans spell colour as
> color LOL. It's so confusing!

That was Daniel Webster.  Don't worry. We'll understand if you want to
include "u".

-MT
Salmon Egg - 30 Jun 2007 07:21 GMT
On 6/29/07 9:53 AM, in article
sKKdnX-AMvixpBjbnZ2dnUVZ_tqnnZ2d@giganews.com, "Mike Tyner"
<mtyner@mindspring.com> wrote:

>> My maternal grandfather is colorblind, my mother is colorblind, I'm
>> colorblind, but my brother is not.  My father is also not colorblind.
[quoted text clipped - 8 lines]
>
> -MT

There is always the possibility of a new kind of colorblindness that is not
carried on an X chromosome. Aside from the possibility suggested by the OP
that his brother is adopted rather than biologically related, there is the
far out chance that his brother has not developed properly from a YY
genotype. If that is the case than his father would have contributed one Y
which is dominant and normal.

Bill
-- Support the troops. Impeach Bush. Oh, I forgot about Cheney.
 
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