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Medical Forum / General / Vision / December 2006

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can lead poisoning cause night blindness?

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efffemm@f-m.fm - 01 Dec 2006 09:14 GMT
I know lead poisoning causes neurological damage of various kinds.
Can it cause night blindness, or is that purely a problem in the
retina?
Mike Tyner - 01 Dec 2006 11:49 GMT
>I know lead poisoning causes neurological damage of various kinds.
> Can it cause night blindness, or is that purely a problem in the
> retina?

Lead poisoning can cause optic neuritis and optic nerve atrophy. That might
show up as "night blindness" but the vast majority of "night blindness"
comes from simple refractive error, made evident by large pupils and
diminished depth-of-field.

-MT
Scott - 02 Dec 2006 01:27 GMT
I think you would be surprised at the number of people who have CSNB (Congenital
Stationary Night Blindness).

>>I know lead poisoning causes neurological damage of various kinds.
>> Can it cause night blindness, or is that purely a problem in the
[quoted text clipped - 6 lines]
>
> -MT
Mike Tyner - 02 Dec 2006 03:33 GMT
>I think you would be surprised at the number of people who have CSNB
>(Congenital Stationary Night Blindness).

That was an interesting google, but from a clinical point of view, most
people who complain of "night blindness" have acquired it as their
refraction changes. How common is CSNB? I can't find specific
incidence/prevalence, but I know the "variable" type of night blindness well
enough.

From a quick review, I'm sure we've all missed some, especially the
"incomplete" type.

But I suspect the incidence among "healthy" people is pretty low. The AD
variety often occurs with albinism, nystagmus, autism, and such. It's
fascinating that the x-linked variety associates with myopia.

-MT
Scott - 02 Dec 2006 19:20 GMT
I have CSNB-X (x-linked).
Myopia is a variable symptom of CSNB. Ranging from mild to severe.
My BCVA is around 20/40 with total night-blindness.
I can drive during daylight hours but not a night.
A male relative (hence the x-link) is faaar less myopic and can drive at night.

>>I think you would be surprised at the number of people who have CSNB
>>(Congenital Stationary Night Blindness).
[quoted text clipped - 12 lines]
>
> -MT
 
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