Tolerance put fingers to keyboard and typed...

It's possible, but not cosmetically desirable - to get your two lenses
looking about the same, you need a smaller 'blank' for the right eye
(otherwise it'll look thicker than the left).

To maximise the effect you need to have a 'knife-edge' on the right lens
i.e. it must be VERY thin around the edge furthest from the optical centre.

In supra/rimless frames you need at least 2mm or more around the edge to
support the nylon cord or screws. By having the edges too thin you weaken
the lens and threfore are more prone to chipping/cracking.

It is no problem to make this Rx into a nylon fit frame. The issues you do
need to be aware of is there will be a little increase in thicknes due to
the edge needing to be 1.5-2.0mm thick at the thinnest point and the
difference in Rx b/w the 2 eyes/ I personally would use a high index,
polycarbonate or 1.67 material, grind the lenses for thickness and multicoat
(always multicoat).

It adds a little to the cost, but they will look so much better, and
factored over a year or 2, is not a major expense.

cheers,

dr grant