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Medical Forum / General / Vision / November 2005

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Different approach 2 eye doctors...

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Thur - 29 Oct 2005 11:44 GMT
About: lasik, pigment dispersion syndrome, eye pressure, glaucoma, timolol,
visual field test

Doctor A (a total of 2 + 2 appointments) - eye doctor at private clinic
- I went in, my eye pressure was measured several times with a tonometer: 28
- They eye was looked at with a gonioscope twice & slit lamp.
- A visual field test was taken and the result was "within normal limits".
- An optic nerve head analysis was taken which showed a "slight
deteriorment" (something about cup to disc ratio, I'm no doctor), because of
high eye pressure in the past.
- Conclusion: pigment dispersion syndrome and was given timolol 0,5% twice a
day (eye pressure drops).
Because of her findings she recommended against doing the lasik eye surgery
(which was the reason I went to that clinic in the first place) and that I
should see my eye doctor at home to check eye pressure regulary.

Doctor B (so far 2 appointments) - eye doctor at hospital
(I gave him the optic nerve head analysis report and the result of the
visual field test)
- I went in, my eye pressure was measures using the "air"-method: 15
- I was taken off the drops for a week to check eye pressure again a week
later.
- A week later the eye pressure was 18, which is normal, so no need for
medication.
- To be certain he wants a visual field test, which will be done next week.

I'm sure the visual field will turn out "within normal limits" and he won't
recommend using timolol. I have the feeling he'd rather wait until it's more
certain and visible that my visual field is deteriorating. The reasoning
behind it is that he doesn't want me to start taking drops from now on twice
a day for the rest of my life (I'm 26), because everything -he says- is just
a borderline case.
Now, I'm not a doctor... but shouldn't one _prevent_ sightloss and start
with eye pressure drops as soon as possible rather than wait any longer
untill my sight _really_ starts to deteriorate? I've been reading about this
syndrome and it is usually detected between the ages of 20 and 40 years,
which is younger than usual and that it doesn't follow the "normal glaucoma
procedure".
A website with a handbook states "... The "watch-and-wait" attitude that you
might use with POAG is not suitable with cases of PG. Prompt, aggressive
therapy is indicated as soon as the diagnosis is evident... " [1] Should I
_again_ espress my concern and irritate the doctor for trying to be a
know-it-all or can I assume he _does_ know the right approach? Am I just
panicking? [2] Because it's also said that fewer than half of the patients
will develop glaucoma (high eye pressure)... [3]
Greetings,

[1] http://www.revoptom.com/handbook/oct02_sec4_4.htm
[2] http://www.krukenbergs-spindle.co.uk/What_can_be_done.htm
[3] http://www.emedicine.com/oph/topic136.htm#section~treatment
Dr. Leukoma - 29 Oct 2005 14:10 GMT
Interesting.  Of course, IOP is often the first indication of risk, and
also the single variable that is treated.  In the absence of any other
finding, a pressure of 28 will not necessarily result in treatment.
The findings of the Ocular Hypertension Study do suggest that benefits
of treatment outweigh the risks at elevated pressures.  However,
elevated pressure may be the result of a thicker than average cornea.
LASIK results in a thinner cornea, hence the IOP must be adjusted
following LASIK, depending on how much tissue is removed.  Figure about
20% reduction.  This reduction can obviously confound the diagnosis.
Also, there is considerable pressure exerted on the optic nerve during
the use of the suction ring.  I think this bothers some glaucoma
specialists who are, after all, trying to save nerve tissue.

Anyhow, back to pressure.  No matter what the pressure, if there is
another positive finding, such as abnormal cupping, abnormally thin
nerve fiber, abnormal visual field, then the diagnosis of glaucoma can
be legitimately made.

Also, of the various methods used to measure pressure, the standard
seems to be Goldmann applanation or some other applanation technique
such as the Tonopen.

I am leaning towards the first diagnosis.  Perhaps you should go for
two out of three.

DrG
LarryDoc - 30 Oct 2005 06:09 GMT
> I am leaning towards the first diagnosis.  Perhaps you should go for
> two out of three.
>
> DrG

As am I and perhaps more consultation is in order.

Dr #1 seems to have done a good work up, so perhaps she should be
consulted again. If you have a good relationship and are willing to
comply with a management plan as outlined below, that might be the
reasonable course of action.

I have a number of patients in my practice with "minor involvement"
pigment dispersion syndrome whose individual pressures sometimes vary
from 16 to 26 over the course of days or weeks.  Most are not on
medication, at least not yet. With PDS, it is important to get optic
nerve stereo photos and OCT, HRT or GDx imaging, along with gonio and
fields. If the patient is willing and able to afford to have Goldmann
tonometry often (sometimes every 4 weeks or more) and nerve imaging
every 4-6 months, it is sometimes reasonable to hold off medication.
Sometimes the pigment exfoliation stops and the pressure stabilizes.
Sometimes, of course, there that situation the system gets clogged for
good and intervention is required.

Certainly in situations where there is not careful patient monitoring,
medication or surgery is the most appropriate option. If imaging studies
show that your nerve health has already been compromised, that means
your pressure has indeed spiked a lot higher than the 28 or has been up
there for too long a time. (Normal fields does not mean the nerve fibers
have not been damaged, only that not enough of them have been
compromised to show up as visual loss.)  In which case medication is
required, even if your pressure on one reading appears normal.

In any event,  PDS may be quite variable and you, in consultation with
your doctor need to decide how much risk you are willing to take and how
much monitoring you are willing to do.

Good luck with your decision and let us know what is decided.

--LB, O.D>
Thur - 31 Oct 2005 21:26 GMT
> Dr #1 seems to have done a good work up, so perhaps she should be
> consulted again.

Thanks for your informative response. I would if I could go back to her, but
that was abroad, hehe.  That's why she gave me the results (optic nerve
photo
and information) and told me to get in contact with my eye doctor at home to
keep an eye on the IOP.

[snip management plan: thanks]
> In any event,  PDS may be quite variable and you, in consultation with
> your doctor need to decide how much risk you are willing to take and how
> much monitoring you are willing to do.

Monitoring is indeed the tricky part on how often one needs (or the doctor
thinks it's needed) to check the eye pressure. I'll have to wait I guess at
what my doctors says I suspect that after my visual field test doctor B will
suggest to check it again in 6 months or so... I have no idea. I also don't
think it would be wise to keep using eye drops against his suggestion (I
have 4 bottles of 5 ml in stock with expiration date 2009). Thanks anyway
:-)
Greetings,
Thur - 31 Oct 2005 21:26 GMT
> LASIK results in a thinner cornea, hence the IOP must be adjusted
> following LASIK, depending on how much tissue is removed.  Figure about
> 20% reduction.

Thanks for your informative response. I gave up on the idea of Lasik, the
reason was that pressure measurement wouldn't be as precies after surgery
and seeing my problem doctor A suggested better to take care of that. Her
exact words were to live happily ever after with glasses.

> Also, of the various methods used to measure pressure, the standard
> seems to be Goldmann applanation. Perhaps you should go for
> two out of three.

Some websites indicate that applanation is more precise than the other
method of a puff of air. Also the general impression of looking at my eye
with that big lens (gonioscopy) and not wanting to do surgery on my eyes
gave me confidence in her findings. After all, not letting me do the surgery
directly affects the private clinic she worked at.
My eye docter at home, doctor B, suggested that if I don't trust him he
would give me permission to go to another hospital (Dutch insurance rules,
you can't just keep hopping along). I didn't say "yes" ofcourse, after all
he _is_ the doctor at the general hospital in the region and it's important
to have a good relationship with the doctor. But still... his different
approach isn't what I expected.
Isn't it better to _prevent_ any vision loss and start with medication in
stead of waiting untill the visual field test shows a vision loss? Thanks
anyway :-)
Greetings,
Mike Tyner - 01 Nov 2005 05:56 GMT
> Isn't it better to _prevent_ any vision loss and start with medication in
> stead of waiting untill the visual field test shows a vision loss? Thanks
> anyway :-)

It's a fundamental question with more than one answer.

It's easy to say "yes" when the patient is young, when there's a strong
family history, when there's good insurance.

Even then, it's prudent to observe over time and look for changes over time,
in the VF or optic nerve photos or OCT, HRT, GDx etc.

Glaucoma is slow, compliance is difficult, and pressures in your range
aren't very reliable for indicating glaucoma.

Pressure measurements are crucial for determining the effectiveness of
treatment, but many people with real glaucoma damage have "normal"
pressures. Conversely, many people with pressures of 30 have no sign of
glaucoma.

Your pigment spindle by itself isn't very alarming. Gonioscopy is much
better for determining your risk.

-MT
 
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