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Medical Forum / General / Vision / October 2005

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reviving the topic "thousands of floaters"

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Autymn D. C. - 21 Sep 2005 09:23 GMT
http://groups.google.com/group/sci.med.vision/tree/browse_frm/thread/1cad9960988
c2fe2/a031aa9cbcfd279a


So where are the explanations already?

I've seen these also, but they shouldn't be called floaters.  They are
best described as a shower of clear, tailed speckles over a small
splotch of sight.  They start at a point, fly out mostly straight but
sometimes bent, then fade out.  The source is usually off-middle of the
splotch.  If they could make a sound, I'd imagine high-pitched rays.
They show up when I look in the low afternoon sky.

-Aut
William Stacy - 21 Sep 2005 15:40 GMT
The dark ones are simply particles of tissue that can range from
transluscent (vitreous) to semi-opaque (blood) floating in the posterior
chamber of the eye.  The lighted ones (photopsia) are probably
neuro/vascular noise that could be anywhere from the retina to the
occiptital cortex.  The treatment is the same.  Ignore.

w.stacy, o.d.

> http://groups.google.com/group/sci.med.vision/tree/browse_frm/thread/1cad9960988
c2fe2/a031aa9cbcfd279a

>
[quoted text clipped - 8 lines]
>
> -Aut
Mike Tyner - 21 Sep 2005 15:45 GMT
> So where are the explanations already?

Could this be it?

http://psychcentral.com/psypsych/Blue_field_entoptic_phenomenon

-MT
Autymn D. C. - 22 Sep 2005 18:45 GMT
> Could this be it?
>
> http://psychcentral.com/psypsych/Blue_field_entoptic_phenomenon

Thanks so much!  But it's
http://en.wikipedia.org/wiki/Blue_field_entoptic_phenomenon.  That's
it.  I had remembered some self-test of HIV by seeing how many white
blood cells were flowing through the sight's field, but didn't have a
size to pin them on.  I'd been thinking that the floaters were the
cells.

William Stacy is a liar who has reading problems.  Seeing sparks may be
a sign of a failing retina.

-Aut
Mike Tyner - 22 Sep 2005 19:40 GMT
> http://en.wikipedia.org/wiki/Blue_field_entoptic_phenomenon.  That's
> it.  I had remembered some self-test of HIV by seeing how many white
> blood cells were flowing through the sight's field, but didn't have a
> size to pin them on.  I'd been thinking that the floaters were the
> cells.

It was the first time I'd heard the Scheerer effect called "floaters."

99.99% of "floater" discussions are about vitreous opacities.

-MT
Don W - 22 Sep 2005 20:06 GMT
William Stacy - 22 Sep 2005 22:03 GMT
Well I've been called a lot of things but usually liar isn't one of
them.  In the context of the thread "thousands of floaters" and the
discussion of central photopsia, I am aware of the theory that
leukocytes are the cause, and have generally dismissed this theory
because of the size of such cells is too small to be visualized by the
human retina.  How do you explain that a cell having a diameter of about
10 microns can be detected by the retina when it is lying close to the
retina?

Anyway, I admit to swimming upstream on this one.  BTW this blue field
phenomenon has nothing at all to do with retinal detachment risk.  The
"sparks" preceeding retinal detachment are huge by comparison, and way
more dramatic.

w.stacy, o.d.

>  
>
[quoted text clipped - 16 lines]
>
>  
Don W - 23 Sep 2005 05:50 GMT
>  How do you explain that a cell having a diameter of about 10 microns can be detected by the retina when it is lying close to the retina?  
 

You don't buy Applegate's computation given (for example) in that before mentioned patent 5016643??

Don W.


William Stacy - 23 Sep 2005 15:27 GMT
OK I'm now ready to concede that the "flying corpuscles" seen in blue
field entoptoscopic observations are indeed most likely due to
occasional leukocytic interruptions in the relatively opaque RBC stream
of the retinal capillaries. It's a fascinating subject with promising
diagnostic potentials in conditions that affect microvasculature of the
eye, like diabetes, glaucoma, etc.

w.stacy, o.d.

>  >  How do you explain that a cell having a diameter of about 10 microns
> can be detected by the retina when it is lying close to the retina?  
[quoted text clipped - 6 lines]
>  
>  
Autymn D. C. - 23 Sep 2005 08:46 GMT
> Well I've been called a lot of things but usually liar isn't one of
> them.  In the context of the thread "thousands of floaters" and the
> discussion of central photopsia, I am aware of the theory that

what discussion?

> leukocytes are the cause, and have generally dismissed this theory
> because of the size of such cells is too small to be visualized by the
> human retina.  How do you explain that a cell having a diameter of about
> 10 microns can be detected by the retina when it is lying close to the
> retina?

The cells could be pushing against the retina?

When I had a lot of free time, I took it to develop a whole new set of
measures, starting with length.  I marked off various scratches on a
stainless steel ruler and eventually estimated that the thinnest line I
could see, when shined upon, was about 1/72 mm or 14 or 15 microns.

> Anyway, I admit to swimming upstream on this one.  BTW this blue field
> phenomenon has nothing at all to do with retinal detachment risk.  The
> "sparks" preceeding retinal detachment are huge by comparison, and way
> more dramatic.

I know it doesn't.  How do the sparks compare to those from
hupertension, poking the optic nerve when the head moves around when
looking up or going into a room?

-Aut
William Stacy - 23 Sep 2005 15:27 GMT
> The cells could be pushing against the retina?

This theory I rejected out of hand when I first saw it a couple of years
ago, because the nano-pressures involved intuitively seem hardly
sufficient to mechanically stimulate a rod or cone. I now believe that
it is simply a matter of ordinary light transmission by the relatively
transparent leukocytes, which does make sense.

w.stacy, o.d.
Autymn D. C. - 24 Sep 2005 17:10 GMT
> > The cells could be pushing against the retina?
>
[quoted text clipped - 3 lines]
> it is simply a matter of ordinary light transmission by the relatively
> transparent leukocytes, which does make sense.

Diffraction helps too.  Ever heard of a Fresnel zone plate?

-Aut
William Stacy - 25 Sep 2005 18:44 GMT
> Diffraction helps too.  Ever heard of a Fresnel zone plate?

Never heard of that, but I would think that diffaction would not be
particularly helpful, since it takes relatively finely focused light and
 spreads it out over rings or lines.

The "flying corpuscles" are very distinct, and relatively sharply
defined, which is one reason I accept the WBC theory. Those retinal
capillaries are right on and in the retina.

One thing that still bothers me is why the flashes are white.  If blue
light is used to bring them out, where does white come from?  I've heard
the notion that maybe they are fluorescing, but I doubt that.  I guess a
 very bright flash of blue against a dimmer blue background could be
perceived as white.

w.stacy, o.d.
Autymn D. C. - 26 Sep 2005 09:21 GMT
Diffraction doesn't need focused light, only fine structures.  A zone
plate is like a bunch of pinholes--more like pinrings--that confocally
magnify light when the magnifier can be any thinness.

I don't know what flashes you're talking about.  The streaks or shower
is not flashy.  It seems the blue light goes into the fringes.

-Aut
William Stacy - 26 Sep 2005 14:24 GMT
I don't think zone plates notion applies to this thread, as they require
 concentric ring apertures that don't exist in the eye.

The flashes that have been discussed in this thread are the "blue field
flying corpuscles" variety. These are indeed "flashy".  I'm not sure
what your last sentence means.

w.stacy, o.d.

> Diffraction doesn't need focused light, only fine structures.  A zone
> plate is like a bunch of pinholes--more like pinrings--that confocally
[quoted text clipped - 4 lines]
>
> -Aut
Autymn D. C. - 27 Sep 2005 12:09 GMT
> I don't think zone plates notion applies to this thread, as they require
>   concentric ring apertures that don't exist in the eye.

Yet small objects still bend liht around them.

> The flashes that have been discussed in this thread are the "blue field
> flying corpuscles" variety. These are indeed "flashy".  I'm not sure
> what your last sentence means.

The streaks are not flashy, but streaky.
William Stacy - 27 Sep 2005 13:57 GMT
Sounds like you're referring to ordinary vitreous floaters.

BTW all the grammar corrections are not needed.  It's acceptible on news
groups to be a bit sloppy as long as your point gets across and makes cents.

w.stacy, o.d.

>>I don't think zone plates notion applies to this thread, as they require
>>  concentric ring apertures that don't exist in the eye.
[quoted text clipped - 6 lines]
>
> The streaks are not flashy, but streaky.
Dan Abel - 27 Sep 2005 17:37 GMT
> BTW all the grammar corrections are not needed.  It's acceptible on news
> groups to be a bit sloppy as long as your point gets across and makes cents.

These private practice doctors!  All the time grubbing after money!

:-)

(making the point that although most spelling and grammar errors are
obvious, some do in fact distort the meaning)
William Stacy - 27 Sep 2005 18:50 GMT
re money grubbing:

the double entendre was intended, of course.

this time...

w.stacy, o.d.
Dan Abel - 27 Sep 2005 20:31 GMT
> re money grubbing:
>
> the double entendre was intended, of course.
>
> this time...

My wife and I are a little anal retentive when it comes to spelling,
grammar and clear writing.  We try to keep it under control, though.

My wife is currently battling the local school board over this, though.  
Their minutes (and some other documents) have spelling errors, grammar
errors, sentences that make no sense whatsoever, and other sentences
that are just plain wrong.  All this could be forgiven, possibly, except
that they all state that the number one goal of the entire school
district is literacy, specifically writing.  My wife has tried to handle
this outside of board meetings, but she just gets ignored.  When she
brings it up at board meetings, she is told that nobody in the district
office has time to proofread, that it is unimportant and that nobody
cares anyway.  This is a legal document, and although 99.9% of the time
it will be totally forgotten once read, it *is* the official and only
record of what was decided.  Occasionally things go to court, and not
only it is an embarrassment to have these errors, the court will rely on
what it written to determine the final decision.  If the parties
disagree as to what is meant, then somebody has to determine what the
original intent was.
William Stacy - 27 Sep 2005 21:09 GMT
>My wife and I are a little anal retentive when it comes to spelling,
>grammar and clear writing.  We try to keep it under control, though.
>
>  

I can appreciate that.  My daughter is now a school teacher and I have a
hard time accepting things like: "That boy is *so* not going to graduate"...

But language evolves, as it doing on s.m.v.

I've gotten over it.

w.stacy, o.d.
Ann - 28 Sep 2005 20:54 GMT
>>My wife and I are a little anal retentive when it comes to spelling,
>>grammar and clear writing.  We try to keep it under control, though.
[quoted text clipped - 7 lines]
>
>I've gotten over it.

LOL... gotten.. you 'mericans and your weird words...
William Stacy - 28 Sep 2005 23:55 GMT
> LOL... gotten.. you 'mericans and your weird words...

I wasn't gonna reply but this thread is so far off it's original topic,
one more aint gonna make no differ'nce.

Aint "gotten" a sure enough good word, bein' a past participle of "get"?

I'm gitten outta here...

w.stacy, o.d.
Autymn D. C. - 29 Sep 2005 15:58 GMT
it's -> its
William Stacy - 29 Sep 2005 16:50 GMT
grammar police -> boring, wasteful of bandwith, unwanted, unappreciated,
endangered species

>it's -> its
>
>  
Autymn D. C. - 30 Sep 2005 11:24 GMT
bandwith -> bandwidth
LarryDoc - 30 Sep 2005 19:10 GMT
> bandwith -> bandwidth

Do you have some other purpose in life other than to waste internet
bandwidth, contributing nothing to actual discussion? Perhaps you're on
a quest to be hired as The Internet Proof-Reader.

Have some respect for the fact that is a global forum and not everyone
is perfectly fluent in English or are expert typists.

Geez, another looney!
Autymn D. C. - 03 Oct 2005 09:15 GMT
> Do you have some other purpose in life other than to waste internet
> bandwidth, contributing nothing to actual discussion? Perhaps you're on
> a quest to be hired as The Internet Proof-Reader.

Yes, look elsewhere.

> Have some respect for the fact that is a global forum and not everyone
> is perfectly fluent in English or are expert typists.
>
> Geez, another looney!

So you would rather they keep making mistakes.  You want people to live
in ignorance.  /You/ are the loony.

-Aut
Autymn D. C. - 28 Sep 2005 14:38 GMT
Editors make everyone else look more literate than they really are.
Autymn D. C. - 28 Sep 2005 14:35 GMT
The "glassy" floaters are not streaky, but drifty.
Don W - 26 Sep 2005 16:47 GMT
> One thing that still bothers me is why the flashes are white.  If blue
> light is used to bring them out, where does white come from?  I've heard
> the notion that maybe they are fluorescing, but I doubt that.  I guess a
> very bright flash of blue against a dimmer blue background could be
> perceived as white.

 Of the papers that I have on the "blue field entopic phenomenon", I cannot
seem to get the specific answer as to why those flashes of the leukocytes
are white against a (relatively pure) blue background.  I don't think they
are fluorescing since one paper used quinacrine to render the leukocytes
fluorescent in an experiment on a bat in this blue field.

Don W.
Mike Tyner - 26 Sep 2005 18:29 GMT
>  Of the papers that I have on the "blue field entopic phenomenon", I
> cannot seem to get the specific answer as to why those flashes of the
> leukocytes are white against a (relatively pure) blue background.  I don't
> think they are fluorescing since one paper used quinacrine to render the
> leukocytes fluorescent in an experiment on a bat in this blue field.

If leucocytes are more transparent than RBCs, they'd form gaps in the
otherwise opaque blood column.

-MT
Don W - 26 Sep 2005 18:47 GMT
>>  Of the papers that I have on the "blue field entopic phenomenon", I
>> cannot seem to get the specific answer as to why those flashes of the
[quoted text clipped - 5 lines]
> If leucocytes are more transparent than RBCs, they'd form gaps in the
> otherwise opaque blood column.

 Yes, also from Applegate's 5,640,220 patent, ....... "The capillaries of
the retina are normally filled with red red blood cells that move in a
single file.  Occasionally, this motion is interrupted by a white blood cell
or a plasma gap.  Since the blue light is almost totally absorbed by the
hemaglobin contained in the red blood cells, light reaches the photoreceptor
only when it is not passing through the red blood cells".  That's from
paragraph 1.2 of his patent.

 But I also don't see the reason for the "white" effect.

Don W.


Mike Tyner - 26 Sep 2005 19:03 GMT
>  But I also don't see the reason for the "white" effect.

Against a blue background, anything brighter and less saturated will seem
"white" by comparison.

These gaps aren't brighter than the background, but the photoreceptors under
a blood column would have to be a little dark-adapted, relative to those
that are fully exposed.

-MT
William Stacy - 26 Sep 2005 19:20 GMT
I have a couple of ideas on this.  One is that the receptors are
relatively "dark adapted" under the shadow of the capillary, and the
sudden stimulus is so great as to overpower the color phenomenon, just
as the sun looks white when you glance at it, when it is probably more
orange.  The other idea is that it's only rods that are so stimulated,
and of course, they are monochromatic.

w.stacy, o.d.

>   Of the papers that I have on the "blue field entopic phenomenon", I cannot
> seem to get the specific answer as to why those flashes of the leukocytes
> are white against a (relatively pure) blue background.  I don't think they
> are fluorescing since one paper used quinacrine to render the leukocytes
> fluorescent in an experiment on a bat in this blue field.
Don W - 27 Sep 2005 19:53 GMT
>> One thing that still bothers me is why the flashes are white.  If blue
>> light is used to bring them out, where does white come from?  I've heard
[quoted text clipped - 9 lines]
>
> Don W.
Autymn D. C. - 23 Sep 2005 08:46 GMT
> Well I've been called a lot of things but usually liar isn't one of
> them.  In the context of the thread "thousands of floaters" and the
> discussion of central photopsia, I am aware of the theory that

what discussion?

> leukocytes are the cause, and have generally dismissed this theory
> because of the size of such cells is too small to be visualized by the
> human retina.  How do you explain that a cell having a diameter of about
> 10 microns can be detected by the retina when it is lying close to the
> retina?

The cells could be pushing against the retina?

When I had a lot of free time, I took it to develop a whole new set of
measures, starting with length.  I marked off various scratches on a
stainless steel ruler and eventually estimated that the thinnest line I
could see, when shined upon, was about 1/72 mm or 14 or 15 microns.

> Anyway, I admit to swimming upstream on this one.  BTW this blue field
> phenomenon has nothing at all to do with retinal detachment risk.  The
> "sparks" preceeding retinal detachment are huge by comparison, and way
> more dramatic.

I know it doesn't.  How do the sparks compare to those from
hupertension, poking the optic nerve when the head moves around when
looking up or going into a room?

-Aut
Don W - 21 Sep 2005 21:43 GMT
> So where are the explanations already?
>
[quoted text clipped - 4 lines]
> splotch.  If they could make a sound, I'd imagine high-pitched rays.
> They show up when I look in the low afternoon sky.

 If they are white blood cells, you should not be seeing them in the
central 5 degrees of vision (of course, in a normal eye).  Only in a ring
around that area.  Some researchers have said that black dots may appear
because of the bunching up of theses cells behind the white ones.  You can
calibrate the vision angle by holding your fist at arm's length.... that's
approximately 10 degrees.  It would be interesting to see, if any way, your
"speckles" are in any way sync'd to the pulse.

Don W.
 
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