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Medical Forum / General / Vision / August 2005

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Epiretinal & Aniseikonia

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lynn - 21 Jul 2005 00:30 GMT
I have diagnosed with an Epiretinal Membrane in my left eye.  I
addition to blurred vision; objects in my left eye appear to be 10-15 %
larger than my right eye.  My corrective lens compensate for a
difference of 4%.

I have chronic tension headaches centered in the forehead.  This has
been a ongoing problem.  I get some relief from botox injections, and
over-the-counter pain medication.  My surgeon does not want to perform
a Membranectomy until my vision is worst than 20/40 corrected in my
left eye.  Any suggestions or help would be appreciated.  I live in the
Dallas, TX area.
Mike Tyner - 21 Jul 2005 01:05 GMT
>I have diagnosed with an Epiretinal Membrane in my left eye.  I
> addition to blurred vision; objects in my left eye appear to be 10-15 %
> larger than my right eye.  My corrective lens compensate for a
> difference of 4%.

So is the aniseikonia something new, supposedly caused by the membrane? I
haven't heard of that. Acquired aniso is much more aggravating than
congenital.

If you wore a minus contact lens on the right eye and then boost the right
spectacle lens by the equivalent plus, you can get much more than 4% size
correction. You might also reverse everything and wear a plus contact on the
left eye with excess minus in the spectacle lens.

The choice depends on whether you're wearing plus or minus now, how your
frame fits, which eye is dominant, which eye is healthier, and other
details.

It isn't usually necessary to neutralize the anisekonia exactly, or even
completely. With trial lenses you can see the effect before making a special
spectacle lens. If you do, keep your old lens.

-MT
William Stacy - 21 Jul 2005 01:35 GMT
>I have diagnosed with an Epiretinal Membrane in my left eye.  I
>addition to blurred vision; objects in my left eye appear to be 10-15 %
>larger than my right eye.  My corrective lens compensate for a
>difference of 4%.
>  

It might be helpful if you'd post your spectacle Rx along with acuities
with the Rx in place. I would assume the membrane has nothing at all to
do with the aniseikonia.

>I have chronic tension headaches centered in the forehead.  This has
>been a ongoing problem.

These may or may not be related to aniseikonia; are probably not related
to the membrane.

> I get some relief from botox injections, and
>over-the-counter pain medication.

So they are at least partly muscle spasm type headaches, I'd guess.

> My surgeon does not want to perform
>a Membranectomy until my vision is worst than 20/40 corrected in my
>left eye.
>  

Post the acuities.  The membrane peel will probably give you better
vision in the left eye, but may have no effect on your headaches or and
will not affect the aniseikonia.

w.stacy, o.d.
lynn - 25 Jul 2005 22:43 GMT
My pre-USAF Vietnam era physical eye exam was Lt. eye 20/10 & Rt. eye
20/15.

Before the epitretianl membrane, their was no headaches nor was there
any difference in image sizes between the two eyes.

Peeling MAY inprove the eye sight.  But there is a good deal of risk
involved with the peeling.

IMHO the epiretinal membrance has a changed the optics causing the
larger image on the Lt. side.
Wearing an eye patch over the Lt. eye reduces the muscle tension in the
forhead but makes for poor depth perception.

Am looking for the best epiretinal surgeon in the country.
William Stacy - 26 Jul 2005 00:38 GMT
OK then since I don't have any Rx data to work with, I'm going to make a
couple of (large) assumptions.  The maculopathy has caused the macula to
move forward, making the left eye more hyperopic, so when you wear a
plus spectacle lens to correct that hyperopia, you have induced
aniseikonia.  If this is true, the aniseikonia may be completely fixable
with a contact lens on that eye.

We've got some good ones here in the Sacramento area.  Where are you?  
Most major metropolitan areas have vitreo-retinal groups.  I'd go to one
of those group practices that only does v/r work.

w.stacy, o.d.

>My pre-USAF Vietnam era physical eye exam was Lt. eye 20/10 & Rt. eye
>20/15.
[quoted text clipped - 13 lines]
>
>  
lynn - 26 Jul 2005 02:00 GMT
The aniseikonia occurs with or without glasses.  Tried contacts but to
no avail.

Will get my prescription this week.

Live in Dallas, TX.  We have the vitreo-retinal groups.  I would prefer
a doctor with loads of experience with ERM removal.
William Stacy - 26 Jul 2005 18:42 GMT
Ok then in view of what Dr. Robins posted, you don't actually have
"regular" aniseikonia, but a special variety of metamorphopsia that the
maculopathy caused.  If I recall correctly, you can't really correct
that much of an image size difference optically, nor would you want to,
since it's not affecting the majority of your fields (only the central 5
degrees or so).  I'm afraid your only fix is to find that special
surgeon for that special, exquisitely delicate procedure.  Good luck.

w.stacy, o.d.

>The aniseikonia occurs with or without glasses.  Tried contacts but to
>no avail.
[quoted text clipped - 5 lines]
>
>  
David Robins, MD - 26 Jul 2005 05:19 GMT
On 7/25/05 4:38 PM, in article SJeFe.462$iM7.134@newssvr21.news.prodigy.com,

> OK then since I don't have any Rx data to work with, I'm going to make a
> couple of (large) assumptions.  The maculopathy has caused the macula to
[quoted text clipped - 26 lines]
>>
>>  

Actually, this is not an uncommon problem. IT IS UNRELATED TO THE MACULA
MOVING FORWARD. This (central) size shift is not really aniseikonia in the
usual sense - it is a metamorphopsia.

What happens is the epiretinal membrane distorts the macula size, making it
smaller (the usual story) or larger. If the photoreceptors are pulls towards
thefova, making it smaller, the same image falls on more photoreceptors, so
the image seems larger than the other eye. However, it is only in the
center. Periphery is unchanged. This causes a disparity in the central image
both not the periphery that locks the eye images together.

This has no optical remedy, since it is not uniform across the image as in
optical aniseikonia due to anisometropia, which can be helped by contact
lenses or "size" lenses, as Dr. Stacy describes above.

The only papers on this describe using Bangerter foils on the lens to blur
the image just enough that the macula image can be ignored, without losing
the use of the periphery. An ophthalmologist that I know had this, and he
also placed a tiny round disk of Scotch Magic tape (the frosted stuff) in
the optimum spot on the glasses to allow him to block out just the macula of
that eye.


David Robins, MD
Board certified Ophthalmologist
Pediatric and adult strabismus subspecialty
Member of AAPOS
(American Association of Pediatric Ophthalmology and Strabismus)
Gerard - 02 Aug 2005 23:00 GMT
I agree with Dr. Robins on the explanation of the aniseikonia
associated with an epiretinal membrane (see also the abstract of a
paper we wrote on this topic below).   As he mentions the aniseikonia
cannot be fully corrected by introducing a constant optical
magnification difference, because the amount of aniseikonia changes
(rather smoothly) with visual field angle.  Nevertheless, partial
relief seems to be possible by searching for and correcting the
aniseikonia at the visual field angle that seems to bother the patient
most.

Gerard de Wit, Ph.D.
Optical Diagnostics
http://www.opticaldiagnostics.com

-----------
Field dependent aniseikonia associated with an epiretinal membrane: a
case study

Gerard C. de Wit, Ph.D. and Cecilia S. Muraki, O.D.

Purpose: Aniseikonia is a binocular anomaly in which the two eyes
perceive images of different size and/or shape.  It is usually assumed
to be constant as a function of visual field angle (i.e. angular
distance from the line of sight).  This is correct for optically
induced aniseikonia, such as the aniseikonia that is associated with
anisometropia and probably also pseudophakia.  The purpose of this
paper is to show that if the aniseikonia is of retinal origin, then the
aniseikonia may no longer be constant as a function of visual field
angle (i.e. field dependent aniseikonia).
Design: Case report, with the patient having a unilateral epiretinal
membrane.
Methods: The aniseikonia was measured in the vertical and horizontal
direction with a customized version of the Aniseikonia Inspector™
software.  The visual field angle was made variable by changing the
dimensions of the size-objects in the direct comparison procedure.
Main outcome measures: Aniseikonia as a function of visual field angle.
Results: The patient exhibited good repeatable aniseikonia ranging from
23% to 2.5% for visual field angles ranging from 0.36° to 5.7°.  In
this range higher angles had lower aniseikonia.  A control subject did
not show this field dependent aniseikonia.
Conclusions: Aniseikonia may vary with visual field angle due to a
retinal origin such as with an epiretinal membrane.  The problem with
field dependent aniseikonia is that it cannot be fully corrected with
conventional optics which exhibits an approximately constant
magnification as a function of visual field angle.  Nevertheless, by
correcting 5-10% aniseikonia which was present in the visual field
angle measurement range at 2° to 3°, our patient had improved visual
comfort, especially for reading.
-----------

> Actually, this is not an uncommon problem. IT IS UNRELATED TO THE MACULA
> MOVING FORWARD. This (central) size shift is not really aniseikonia in the
[quoted text clipped - 23 lines]
> Member of AAPOS
> (American Association of Pediatric Ophthalmology and Strabismus)
 
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