I believe this product works best when pigs fly out of my a.s to
instill the drops.
On a serious note, the field of botanicals and holistic medicines is
virtually unregulated by the FDA.  The "snake oil salesmen" love to use
the patient's natural fear of eye surgery to sell them on the dream of
"dissolving" their cataracts.  This product is at best a work of
fiction and at its worst it might bring non-sterile solutions to an
innocent, virgin eye.  Be very careful.  I have seen some very nasty
eye infections in patients who were infected by their non-sterile
homeopathic "medicine".

If it works, it would be equivalent to changing a hard boiled egg back to
its raw state.  The newspaper article contains factual errors about what
cataract is and where in the eye it is located.

PubMed has only one clinical trial, with a very small group of subjects and
it was conducted by researchers employed by the manufacturer.

Dr Judy

N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent
ophthalmic drug in treatment of human cataracts.

Babizhayev MA, Deyev AI, Yermakova VN, Semiletov YA, Davydova NG, Kurysheva
NI, Zhukotskii AV, Goldman IM.

Innovative Vision Products, Inc., County of New Castle, DE 19810, USA.
markbabizhayev@mail.ru

A study was designed to document and quantify the changes in lens clarity
over 6 and 24 months in 2 groups of 49 volunteers (76 eyes) with an average
age of 65.3 +/- 7.0 enrolled at the time of diagnosis of senile cataracts of
minimal to advanced opacification.The patients received N-acetylcarnosine,
1% sol (NAC) (26 patients, 41 eyes = Group II), placebo composition (13
patients, 21 eyes) topically (two drops, twice daily) to the conjunctival
sac, or were untreated (10 patients, 14 eyes); the placebo and untreated
groups were combined into the control (reference) Group I. Patients were
evaluated upon entry, at 2-month (Trial 1) and 6-month (Trial 2)-intervals
for best corrected visual acuity (b/c VA), by ophthalmoscopy and the
original techniques of glare test (for Trial 1), stereocinematographic
slit-image and retro-illumination photography with subsequent scanning of
the lens. The computerized interactive digital analysis of obtained images
displayed the light scattering/absorbing centers of the lens into 2-D and
3-D scales.The intra-reader reproducibility of measuring techniques for
cataractous changes was good, with the overall average of correlation
coefficients for the image analytical data 0.830 and the glare test readings
0.998. Compared with the baseline examination, over 6 months 41.5% of the
eyes treated with NAC presented a significant improvement of the gross
transmissivity degree of lenses computed from the images, 90.0% of the eyes
showed a gradual improvement in b/c VA to 7-100% and 88.9% of the eyes
ranged a 27-100% improvement in glare sensitivity. Topographic studies
demonstrated less density and corresponding areas of opacification in
posterior subcapsular and cortical morphological regions of the lens
consistent with VA up to 0.3. The total study period over 24 months revealed
that the beneficial effect of NAC is sustainable. No cases resulted in a
worsening of VA and image analytical readings of lenses in the NAC-treated
group of patients. In most of the patients drug tolerance was good. Group I
of patients demonstrated the variability in the densitometric readings of
the lens cloudings, negative advance in glare sensitivity over 6 months and
gradual deterioration of VA and gross transmissivity of lenses over 24
months compared with the baseline and 6-month follow-up examinations.
Statistical analysis revealed the significant differences over 6 and 24
months in cumulative positive changes of overall characteristics of
cataracts in the NAC-treated Group II from the control Group I.The
N-acetylated form of natural dipeptide L-carnosine appears to be suitable
and physiologically acceptable for nonsurgical treatment for senile
cataracts.

Publication Types:
 a.. Clinical Trial
 b.. Randomized Controlled Trial