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Medical Forum / General / Vision / April 2005

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Purevision?

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MS - 22 Apr 2005 05:53 GMT
Are they legally available in the USA yet, being prescribed here, etc.?

How do people find they compare with N&Ds?
Dr. Leukoma - 22 Apr 2005 13:09 GMT
The new roll-out date has been pushed back to later this month, with
the toric version coming in June.  I am on the list for inventory.

I always liked the Purevision, and up until a few weeks ago I continued
to wear them (expired trial lenses from my old inventory).  Optically,
I think they are great, but the Focus N&D is very close.  The DK is
slightly less than the Ciba products.

I think the lenses are very comparable to each other.  The Purevision
is a very comfortable lens with inherently great optics because of its
modulus.  It is probably the stiffest lens available, which means that
the surface deforms less during actual wear.  It also has unbelievable
surface wettability.

DrG
Andrew Chew - 22 Apr 2005 16:12 GMT
> The new roll-out date has been pushed back to later this month, with
> the toric version coming in June.  I am on the list for inventory.
[quoted text clipped - 3 lines]
> I think they are great, but the Focus N&D is very close.  The DK is
> slightly less than the Ciba products.

What's DK?
Neil Brooks - 22 Apr 2005 16:35 GMT
>> The new roll-out date has been pushed back to later this month, with
>> the toric version coming in June.  I am on the list for inventory.
[quoted text clipped - 5 lines]
>
>What's DK?

D = Diffusion Coefficient of lens material
k = Oxygen Solubility of lens material

A measure of their oxygen permeability.  A function of water content.

Lower water content = lower Dk

Dk/T = oxygen permeability per lens thickness

Basically: More oxygen to the cornea = better eye health
Dr. Leukoma - 22 Apr 2005 16:45 GMT
Actually, with conventional hydrogels, the Dk is directly proportional
to the water content, up to the diffusion coefficient of oxygen in
water.

With silicone-hydrogels, the Dk is inversely related to the water
content and directly related to the silicone content.  The Purevision
water content is slightly higher than Focus N&D.

With respect to the oxygen needs of the cornea, there is something
called a threshold, beyond which additional oxygen is of no greater
benefit.

DrG
Andrew Chew - 23 Apr 2005 04:36 GMT
> Actually, with conventional hydrogels, the Dk is directly proportional
> to the water content, up to the diffusion coefficient of oxygen in
[quoted text clipped - 3 lines]
> content and directly related to the silicone content.  The Purevision
> water content is slightly higher than Focus N&D.

Doesn't that mean Purevision would tend to be drier than Focus N & Ds? I
read somewhere the higher the water content of the lenses, the more they
absorb water from without?

> With respect to the oxygen needs of the cornea, there is something
> called a threshold, beyond which additional oxygen is of no greater
> benefit.

Is this threshold exceeded by Purevision or Focus N & Ds?
Dr. Leukoma - 23 Apr 2005 13:38 GMT
> Doesn't that mean Purevision would tend to be drier than Focus N & Ds? I
> read somewhere the higher the water content of the lenses, the more they
> absorb water from without?

Is that so?  Why is it that a hydrogel lens called Proclear, which has
a 62% water content and no silicone, performs well on many patients
with dry eyes?  The ostensible reason is that the material attracts and
holds water to the surface of the lens.  There is indeed more to the
science than just water content.

> Is this threshold exceeded by Purevision or Focus N & Ds?

It depends on whether you accept the Holden criterion or the revised
Holden-Mertz criterion, i.e. whether you believe that the overnight
amount of swelling in an eye without a contact lens is 4% or less than
4%.  If you accept the revised criterion, then the Focus N&D exceeds it
and the Purevision doesn't.

DrG
The Real Bev - 22 Apr 2005 22:31 GMT
> The new roll-out date has been pushed back to later this month, with
> the toric version coming in June.  I am on the list for inventory.
[quoted text clipped - 9 lines]
> the surface deforms less during actual wear.  It also has unbelievable
> surface wettability.

I looked at some Brit sites, which listed only Purevision minus-power torics.
Is that possible?

Signature

Cheers, Bev
===================================================
Red ship crashes into blue ship - sailors marooned.

Dr. Leukoma - 23 Apr 2005 03:22 GMT
Not only is it "possible," but probable.

O2 Optix was "rolled-out" in the prescription range of -1.00 to -6.00.
How tepid is that?  Didn't they have enough confidence in their own
product?

DrG
Dr Judy - 23 Apr 2005 17:22 GMT
>> The new roll-out date has been pushed back to later this month, with
>> the toric version coming in June.  I am on the list for inventory.
[quoted text clipped - 13 lines]
> torics.
> Is that possible?

I've been using PV toric on patients since Sept 04 here in Canada.  I got it
on the "pre launch" due to my high volume CL practice, I do not think it is
in general release here yet.

Dr Judy
Dr Judy - 23 Apr 2005 17:20 GMT
> Are they legally available in the USA yet, being prescribed here, etc.?
>
> How do people find they compare with N&Ds?

Don't know about the US.  I'm in Canada, where Purevision was never off the
market.  PV has a visibility tint which N&D lacks.   I've tried patients
with "Coke/Pepsi" test of PV vs N&D: results slightly in favour of PV but,
frankly, neither one is consistently preferred by all.

The fit is slightly different so one suits some people, the other suits some
people.  Some people find PV dries/ coats more than N&D, some people find
the opposite and some find no difference.  Generally, both lenses are
preferred over conventional hydrogel materials.

Dr Judy
 
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