In macular degeneration, how well do the symptoms reported by the patient
correlate to what the ophthalmologist sees via OCT and direct retinal
photographs? That is, can the ophthalmologist "see ahead" of the reported
symptoms, or is the "inside view" always better? Or what....?
Mike Tyner - 17 Apr 2005 22:29 GMT
> In macular degeneration, how well do the symptoms reported by the patient
> correlate to what the ophthalmologist sees via OCT and direct retinal
> photographs? That is, can the ophthalmologist "see ahead" of the reported
> symptoms, or is the "inside view" always better? Or what....?
Often the retinal signs precede vision loss by many years, so regular
examinations are most important in detecting AMD early.
Once AMD develops, patient monitoring with Amsler grid is an essential part
of treatment because you can detect blind spots and stretching about as
accurately as the best instruments. Other problems (like neovascular nets)
don't affect your subjective vision enough to be reliable.
I haven't seen figures comparing OCT in AMD management, but I'm pretty sure
fluorescein angiography is still the best way to identify areas that need
treatment.
-MT
RM - 18 Apr 2005 00:58 GMT
> In macular degeneration, how well do the symptoms reported by the patient
> correlate to what the ophthalmologist sees via OCT and direct retinal
> photographs?
Not well. For example, you can find patients that seem to have advanced AMD
by fundoscopic exam but also have excellent Snellen acuity. Vice versa, you
can find patients who seem to have nothing more than some minor pigment
mottling but have lost 1-2 lines of acuity.
Don W - 18 Apr 2005 02:32 GMT
Interesting about the Snellen acuity. The drug Macugen, in the FDA
trials, used this type of test to get approval.
>> In macular degeneration, how well do the symptoms reported by the
>> patient correlate to what the ophthalmologist sees via OCT and direct
[quoted text clipped - 4 lines]
> versa, you can find patients who seem to have nothing more than some minor
> pigment mottling but have lost 1-2 lines of acuity.