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Medical Forum / General / Vision / February 2005

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Will eyedrops to reduce intraocular pressure improve myopia?

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Andrew Chew - 05 Feb 2005 07:10 GMT
Penny for your thoughts...
LarryDoc - 05 Feb 2005 07:57 GMT
> Penny for your thoughts...

Yes! My patent on the drops will make me a huge fortune, and I'll be
retired to my private island in the Caribbean, surrounded by legions of
worshipers in plano sunglasses.

--LB, O.D.
Andrew Chew - 05 Feb 2005 09:49 GMT
>> Penny for your thoughts...
>
[quoted text clipped - 3 lines]
>
> --LB, O.D.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=14740545


I guess once IOP has stabilised, by the eye having increased in size, it
might be too late to reverse myopia.
Andrew Chew - 05 Feb 2005 09:54 GMT
>>> Penny for your thoughts...
>>
[quoted text clipped - 8 lines]
> I guess once IOP has stabilised, by the eye having increased in size, it
> might be too late to reverse myopia.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=14693759


This one debunks any association whatsoever.
otisbrown@pa.net - 05 Feb 2005 21:39 GMT
Dear Andrew,

Subject:  Tests using atropine (drops) to determine the
             effect on the refractive status of the eye.

There was a study conducted by on researcher who used
a "drop" in one eye -- and not the other.

(i.e., the atropinze paralyzed "accommodation")

The result was that the eye (in which accommodation was
"prevented") stablized, and the other eye continued
into myopia at a rate of about -;3/4 diopter per year.

(One eye relative to the other.)

I do not have the "text" of the study, but that
is what I recall.

Best,

Otis
Engineer
Neil Brooks - 05 Feb 2005 21:41 GMT
This posting is an automatic reply to any sci.med.vision newsgroup thread
that is receiving comments from a person named "Otis", "Otis Brown",
"otisbrown@pa.net" or "Otis, Engineer".

Otis is not an expert in any field of vision. His medical and eyecare
training is nil.

In addition, Otis continually misquotes people in his posts. He drops the
names of doctors whom he falsely claims to be associated with.  He has been
caught in out-and-out lies. He has given people incorrect medical advise.
Sadly, his behavior suggests he may have psychological problems that compel
him to argue against people just for the sake of causing an argument.

Otis is what is known in internet newsgroup lingo as a "troll".  Do not
reply to his postings-- it just takes up bandwidth and storage space that
should be reserved for meaningful topics.  It also just fulfils his sick
psychological needs.

No one means to suppress the honest opinions of others.  This message is
only meant to forewarn anyone who might misconstrue Otis as a trained
eyecare expert.

Don't waste your time with Otis.

Please see the weekly posting "welcome to sci.med.vision" which usually
appears on Mondays, for information on how to filter out Otis' posts so that
you may be able to participate in worthwhile discussions in this forum.
Mike Tyner - 06 Feb 2005 00:45 GMT
> The result was that the eye (in which accommodation was
> "prevented") stablized, and the other eye continued
[quoted text clipped - 4 lines]
> I do not have the "text" of the study, but that
> is what I recall.

That's the problem with relying on limited recall of limited understanding.

Pirenzipine does not significantly interfere with accommodation, but it
slows myopia about as well as atropine. BOTH are significantly more
effective than plus lenses.

Google "muscarinic receptors" and you'll see that there are different types
of "atropine" receptors all over the body.

-MT
otisbrown@pa.net - 06 Feb 2005 03:44 GMT
Dear Andrew,

This report does not discuss IOP, so you will have to draw
your own conclusions.

This IOP is an "intermediate" step.  The real question
concerns the "prevention" of nearsighedness using
"drops".

Report:

Bedrossian, R. H., "The Effect of Atropine on Myopia",
Annals of Ophthalmology", 3 (8):  890-899 (In this
study of myopia development, accommodation is
one eye was prevented with atropine, while
the other eye was not.  Result:  The atropinized
eye stablized, while the not-atropinized eye
progressed into myopia.)

Hope this partly answers your question.

Best,

Otis
Engineer

[  You can "skip" the warning "borad-side".  This is a published
scientific report.  Andrew can draw his own conclusions.  OSB]
RM - 06 Feb 2005 19:12 GMT
> This IOP is an "intermediate" step.  The real question
> concerns the "prevention" of nearsighedness using
> "drops".

Otis tries to redefine all topics so he can start his biased diatribe again.
Reader Beware!!

And so--

This posting is an automatic reply to any sci.med.vision newsgroup thread
that is receiving comments from a person named "Otis", "Otis Brown",
"otisbrown@pa.net" or "Otis, Engineer".

Otis is not an expert in any field of vision. His medical and eyecare
training is nil.  He is a proponent of a myopia prevention technique that is
unproven.

In addition, Otis continually misquotes people in his posts. He drops the
names of doctors whom he falsely claims to be associated with.  He has been
caught in out-and-out lies. He has given people incorrect medical advise.
Sadly, his behavior suggests he may have psychological problems that compel
him to argue against people just for the sake of causing an argument.

Otis is what is known in internet newsgroup lingo as a "troll".  Do not
reply to his postings-- it just takes up bandwidth and storage space that
should be reserved for meaningful topics.  It also just fulfils his sick
psychological needs.

No one means to suppress the honest opinions of others.  This message is
only meant to forewarn anyone who might misconstrue Otis as a trained
eyecare expert.

For anyone who is interested in understanding the current state of
scientific/medical research on myopia prevention, I offer the following
link: http://annals.edu.sg/pdf200401/V33N1p4.pdf.  If you have other topics
you wish to discuss, there are experts here who will usually help you.
Don't waste your time with Otis.

Please see the weekly posting "welcome to sci.med.vision" which usually
appears on Mondays, for information on how to filter out Otis' posts so that
you may be able to participate in worthwhile discussions in this forum.
Dr Judy - 05 Feb 2005 18:38 GMT
>>> Penny for your thoughts...
>>
[quoted text clipped - 8 lines]
> I guess once IOP has stabilised, by the eye having increased in size, it
> might be too late to reverse myopia.

The article you posted in no way  implys IOP is a cause of myopia.  The
study is very suspect anyway, as refractive error was measured by non
cylcoplegic autorefraction, which is notorious for over estimating myopia in
non presbyopes.  If the idea was to suggest that high IOP caused enlongation
of the eye, the study should have used ultrasound scans to measure eye
length.

Dr Judy
 
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