I believe that Kathleen Turner has been taking Enbrel for a few years (its
been discussed in ASA frequently).

The Guardian did a smashing interview with her last Saturday, which was a
bit more balanced.  I've pasted a bit below.

Its a shame though that everyone expects her too look as she did in Body
Heat - I know I look nothing like I did 25 years ago.

Jayne

Though Turner continued to make some critically acclaimed movies in her
40s - the repressed mother in Sofia Coppola's The Virgin Suicides, a
homicidal matriarch in the satirical Serial Mom - a diagnosis of rheumatoid
arthritis in 1993 certainly did not help a film career that was already
shifting gear. Daily intake of steroids to control pain and severe joint
swelling caused her to gain weight; the tabloids had a field day suggesting
she had let herself go with drinking and overeating. Nor did she contradict
them.

"It hurt me very much what they wrote, [she is now in remission with
medication and back to her slim form] but I was frightened if the industry
knew I was sick, it might hurt my career." Hollywood, she points out, can be
a very forgiving town, except if you're ill. "Look at all the actors who are
known drunks, go to jail for drugs, come out of rehab and go right back to
work. But for me to tell people about it, they would have run."

She says that while the worst of it was the loss of mobility - "I have
always been a great athlete, and suddenly to lose this portion of myself was
devastating" - she understood why the public's reaction was centred on her
perceived loss of sexuality. Sex symbols, she explains, are expected to be
frozen in time. "People were saying, look, her face is getting heavier,
comparing me to who I was 20 years ago. Which makes no sense. They didn't
stop growing or changing, why would I look the same? And if I did look the
same, is that not bizarre?"