Hello,
I had the same choice to make in December...........I chose Adalimumab
(Humira)mainly because the injections are every two weeks rather than
twice weekly.  I have never injected myself before and thought that the
fewer the better.  Everything has gone so well.  I have had no problems
with injecting myself, but am glad that I only have to do it
fortnightly.  I had a urine infection shortly after starting the
treatment which was successfully treated with antibiotics and have had
nothing since.  The benefits make the risk worthwhile in my
opinion.................quality of life is the most important factor.
Besides the leaflets there is a lot of information on the internet.

Kate

It is certainly more convenient to inject once every two weeks instead
of twice a week and given the choice I would personally choose Humira.
In fact I would change from Enbrel to Humira if I got the chance.

As far as I can judge there is not much difference in efficacy between
them. But there still seems to be some idiosyncracy.

Peter

I'm an Enbrel user, and thank my lucky stars every day for it.  Life isn't
perfect with Enbrel, but it is zillions better than life was 2 years ago.

I've been on Enbrel for 2 years this month (how time flies eh!).  I can go
about my business quite well considering.  Two years ago, I couldn't scratch
the back of my own neck, or wash my own hair, as I couldn't raise my arms
and bend my elbows enough.  My hands look more normal than they did too.  It
can't help the damage already done - I've recently had one knee replacement
and am due the other later this year.

There are some of us here on Humira (Adalimumab), and a couple on Enbrel.

I really wish your wife all the best with her decision.  I worried over the
infection risk at first, but I've always been quite hardy as far as
infections go, and haven't had one in the two years I've been taking it.  In
fact, I don't think I've seen my GP since before the treatment started,
which has to be good!

Jayne