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Medical Forum / Diseases and Disorders / Tinnitus / May 2004Can METHAZOLAMIDE and ACETAZOLAMIDE be used 'interchangably'?
I have been unable to locate methazolamide where I am but there is quite a bit of acetazolamide around. Can these two categories of drugs be used interchangably? Thank you in advance, FP Mehtazolamide seems to work better and has fewer side effects, though they are similar in action. Murray Grossan, M.D. http://www.ent-consult.com > Mehtazolamide seems to work better and has fewer side effects, though they are similar in action. Thank you very much. I will talk to my GP in HK about that. Last time he recommended me to take Lasix after failing to locate methazolamide. For the past few days, I have been taking 20 mg of Lasix every other day or on only the 'bad' day. The outcome has been that a 'bad' day continues to be as noisy as it was before but is no longer associated with anxiety and discomfort like how it was previously. I have been experiencing the discomfort from this 'positional' pressure on the left side of my head for the past 6 months and found the use of diurectics to be able to release it. I would appreciate, and my ENT doctor too, if you could share your educated judgement on _what_ causes this pressure. My ENT doctorS and other doctorS here in China have been subscribing, by their training, to the view that all the troubles of my T have come from the poor blood circulation in the inner ear and I have been led into the path for the past 6 months. It is about time I would like to be enlightened by a different view. Thank You in advance, FP > Murray Grossan, M.D. > http://www.ent-consult.com there is an enzyme called the carbonic anhydrase enzyme. It works in the kidney, eye and inner ear to put fluid into a chamber. Methazolamide and Diamox work on this enzyme so less fluid is put into the inner ear. Combined with low salt high potassium diet, this can be theraputic. The pressure you feel is actually the fluid pressure in the inner ear. Murray Grossan, M.D. http://www.ent-consult.com > there is an enzyme called the carbonic anhydrase enzyme. It works in the > kidney, eye and inner ear to put fluid into a chamber. Methazolamide and Diamox work on this enzyme so less fluid is put into the inner ear. Combined with low salt high potassium diet, this can be theraputic. The pressure you feel is actually the fluid pressure in the inner ear. Thank you so much. My doctorS here in Hong Kong and in the mainland are more interested in making money than in continuing education and are too much so to have advised me on this. On the rationale presented above, would you say it is better to use a diurectic that restricts the input of fluid into the ear than a diurectic like Lasix that takes fluid out? FP =========================== > Murray Grossan, M.D. > http://www.ent-consult.com I personally never use Lasix as it is not a carbonic anhydrase inhibitor. Murray Grossan, M.D. http://www.ent-consult.com > I personally never use Lasix as it is not a carbonic anhydrase inhibitor. Thank you very much one more time. I suppose there is no need to check with my GP who prescribed Lasix to me after failing to find methazolamide. I could just go ahead to consult an eye specialist here in China on how to take this medicine. Diamox is mostly prescribed by eye doctors. When I told my ENT doctor about using DIAMOX, he was so surprised as if he had discovered something celestial. I am beginning to feel that somehow a visit to a Chinese doctor trained in western medicine here in China carries the same elements of risk as a visit to a WASP doctor who, after taking a few courses in herbalist medicine, begin to practice herbal treatments in the US...LOL/ FP > Murray Grossan, M.D. > http://www.ent-consult.com This is not a reflection on your doctor at all. My methods are based on my understanding of physiology and not on the textbook, so there is no reason for your doctor to know my methods. Murray Grossan, M.D. http://www.ent-consult.com I have the pills here. The eye doctor said DIAMOX has to be taken with sodar pills and pills that replace potassium loss, and cited me a few unpleasant side-effects. More questions before starting the treatment: (1)For tinnitus patients, how should these pills be taken; once a day or twice a day. Could I do it every other day? etc.. The eye specialist and the ENT doctors here are not aware that DIAMOX could be used to treat T patients. I have bought the 0.25 mg pills. (2)How long should the treatment last? Is this a lifetime commitment? (3)What would you tell me in addition to the above before I start. Thank you in advance, FP ===================================================== > I personally never use Lasix as it is not a carbonic anhydrase inhibitor. > Murray Grossan, M.D. > http://www.ent-consult.com Diamox is not a cure for tinnitus. when there is hydrops or increased fluid pressure in the inner ear, it is what I use to lower that fluid pressure. There are as many causes of T and there are eye conditions. Murray Grossan, M.D. http://www.ent-consult.com > Diamox is not a cure for tinnitus. when there is hydrops or increased fluid > pressure in the inner ear, it is what I use to lower that fluid pressure. After talking to his books and professor, my ENT doctor in China is still scratching his ball on this 'hydrops' thing. His simple mind suggests to him that if a patient is not experiencing vertigo or dizziness, where on earth that 'hydrop' comes from! On the other hand, he has once again failed to explain why the use of diurectic has been successful in releasing the positional pressure on the left side of my head. So he is not encouraging at all on the use of Diamox. As a matter of fact, he does not think I need Lasix too. Lasix was prescibed to me by a Hong Kong doctor upon *my* request for a pill that could release my head pressure without creating a 'stedio effect' like Dyazide. Prior to that he prescribed me to take prosac for the release of that pressure. Thus for the time being I will try to get by with Lasix. I take 20 mg of Lasix on the 'bad' day only. The good thing about this diurectic is that it allows me to habituate more easily on a bad day. That is to say, the noise is still there on a bad day but is no longer associated with anxiety and tense feeling. And there is no 'stedio effect' like Dyazide. In addition, the use of this diurectic has helped the bowel movement. Before you lose patience with me, let me ask you one more time to help me and my doctorS in China shed some light onto this puzzle. The puzzle is about this positional pressure in my head travelling from side to side, and in doing so creating a phenomenon of one good day being followed, quite regularly, by a bad day which is to be followed by another good day again. Would it be possible that this 'positional pressure' i have been complained about comes from body parts other than the inner ear??? Thank you in advance, FP p.s. Would appreciate if you could send me an email aside from replying to my post on the ng. Somehow the software at Google and the ISPs in China don't click that well. > There are as many causes of T and there are eye conditions. > Murray Grossan, M.D. > http://www.ent-consult.com > I personally never use Lasix as it is not a carbonic anhydrase inhibitor. The problem is: while the GP that recommends me to take Lasix is an Oxford guy in Hong Kong and speaks with authority, my ENT doctor in China that 'finally' suggests me to 'try out' Diamox speaks like a whimp as he is not well versed in western medicine. I have no confidence with him. When I return to NA, I will make an effort to visit your clinic. Thanks, FP ================================== > Murray Grossan, M.D. > http://www.ent-consult.com |
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