>A couple of years ago there was a huge study in the UK. It was a
>double-blind randomized placebo controlled study in which the
>principal investigator, Ewert Davies, and his team demonstrated rather
>convincingly that Ginkgo biloba was no more effective than placebo in
>treating tinnitus.
>As in all studies on Ginko the doses were far smaller than the ones
>taken by people for whom it was effective.
................
I have heard that criticism, Elly. In fact Dr. Michael Seidman,
Director of the Henry Ford Health Systems Center for Complementary &
Integrative Medicine in Michigan, frequently uses that argument to
support his position on the efficacy of ginkgo.
What I don't understand is - *IF* that is the case - why in the world
would Ewart Davies, one of the world's most respected tinnitus
researchers, do a ginkgo study with inadequate dosing. It just
doesn't make sense to me.
I'm going to e-mail him at the last e-mail address I have for him -
and see what his thoughts are. If I get a response, I'll post the
information here.
smn
Elly Byrne - 21 Jan 2004 19:37 GMT
Michael Seidman, M.D. The study you are referring to was a nice study
out of the United Kingdom. Unfortunately, the dose that they tested
was about 1/3 of the dose that has been shown to be of some benefit. I
usually recommend 240 mg, two times per day; the study used 160 mg. In
science there are ALWAYS studies that prove one thing and then the
next study proves the opposite. Remember how bad butter was for you,
and we were to switch to margarine? Now the trans fats are seen to be
much worse than butter. The only thing constant is change!
Tinnitus is a pain in the neck
Elly's Tinnitus Resources
http://www.eebee.net/
http://www.tinnitusrelief.net/
For email: elly at eebee.cjb.net
>>As in all studies on Ginko the doses were far smaller than the ones
>>taken by people for whom it was effective.
[quoted text clipped - 16 lines]
>
>smn
ENTconsult - 23 Jan 2004 07:20 GMT
There is Gingko from root, stem, leaves and "whatever". 100 gms of Gingko
WHAT? root, etc.
Last time I looked only the German products were uniform.
My position is that unless there is a real assurance of success, the
possibility of bleeding - or worse - with large doses is something to seriously
consider.
One of my peers said that the reason we haven't seen more "bleeding" with
Gingko in large doses is that the stuff they sell "at the store" is probably
from the ineffecive areas of the plant.
Poor circulation is only ONE of the possible causes of T.
Murray Grossan, M.D.
http://www.ent-consult.com
Stephen Nagler - 03 Feb 2004 14:50 GMT
>>As in all studies on Ginko the doses were far smaller than the ones
>>taken by people for whom it was effective.
[quoted text clipped - 16 lines]
>
>smn
..................
Here is the response I just received from Dr. Davies:
>With regards to Ginkgo, even expressing the concentration is
>difficult. Some people speak of leaf content whilst others speak of one or
>both of the active components. We derived our dosage from the recommendation
>of the manufacturers who claimed that the concentration used would be ample
>to show an effect if it was there.
Seems reasonable to me!
smn