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Medical Forum / Diseases and Disorders / Tinnitus / December 2006

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Tinnitus and Prilosec

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Dave C. - 27 Dec 2006 22:32 GMT
I came across the information below about misoprostol helping tinnitus.  An
excerpted paragraph is as follows:

QUOTE:

A medication prescribed to protect the stomach from ulcers may also provide
benefit for tinnitus sufferers. One small, controlled trial of Cytotec
(misoprostol) found that it worked twice as well as placebo to relieve
tinnitus loudness (Otolaryngology-Head and Neck Surgery, May 2004). Cytotec
can cause diarrhea, abdominal pain, nausea and flatulence. It can also cause
premature labor or miscarriage so pregnant women must avoid it.

END QUOTE

The complete article is in the link at the end of this post.

I had been taking Prilosec, 10mg, mornings and an occasional one in the
evening.  After reading the above, I increased the dose to 20mg (with my
doctors permission) and 10mg or 20 mg at supper.

The signal I had got was that the tinnitus increased usually a few hours
after eating.  Well, this has lessen ringing noticeable.  My physician says
I can take 20mg twice a day with no problem.

Anyone have any thoughts or experience with this?

Dave C.

http://www.peoplespharmacy.com/archives/editorial/new_hope_for_people_with_ringi
ng_in_the_ears.asp

lennybruce71@googlemail.com - 28 Dec 2006 16:03 GMT
Hi Dave,

you are talking about two different drugs: you are getting Prilosec
(molecule: omeprazole)
... instead the study has been done on Cytotec (molecule:
misoprostol)...

I dont' understand...

Happy new year!
Lenny

> I came across the information below about misoprostol helping tinnitus.  An
> excerpted paragraph is as follows:
[quoted text clipped - 25 lines]
>
> http://www.peoplespharmacy.com/archives/editorial/new_hope_for_people_with_ringi
ng_in_the_ears.asp
Dave C. - 28 Dec 2006 21:51 GMT
Hi Lenny, yes, you are right on that, but here is the way it went:

After I saw that article on msoprostol, I talked to my physician he did
mention it was a different med.  But he saw no problem increasing the
omeprazole to 20mg once or twice a day as a trial and if I get relief then
continue with it.

He briefed me about a nerve connection between the stomach area and the ear
area and that is what often causes vomiting with vertigo or sea sickness.
And he suggested that maybe omeprazole and msoprostol cause a calming
effect.

Well, taking 20mg omeprazole first thing in the morning has been giving me
almost total relief.  Later on I might add 20mg at supper.

Now, some recent history (if you want to read on):

I had been taking omeprazole, 10mg, for a number of years.  Since I had my
recent bout with vertigo (in hospital 4 days, needed a walker for 4 days,
cane for 4 days, vomiting, etc). The ENT said it in my case can take from 2
to 4 months to recover.

I am in my 3rd month right now. Clinically, the MRI and CT were negative, no
infection, hearing test normal, blood sugar is normal, allergy test for 50
foods was negative. The ENT diagnosed it as vestibular neuritis or labyrinth
inflammation.

Well, anyway, since then, what I have been left with is tinnitus (along with
left ear ache and some neck pain) which seems to be triggered by eating
meals, especially eating simple carbs.  And it takes a day or so to go away
after careful eating.  That was the key, in that it would go away
predictably then return rather than being constant all the time.  Again, my
physician said that on the outside, omeprazole may cause a calming effect in
the stomach and indeed in my case it has given me quite a bit of relief.

I am pretty much at the limit of my knowledge in these matters, but the
results seem to work out OK for me.  I do recognize that everyone is
different.  It seems that no two stories of tinnitus are the same.

Dave

> Hi Dave,
>
[quoted text clipped - 42 lines]
>>
>> http://www.peoplespharmacy.com/archives/editorial/new_hope_for_people_with_ringi
ng_in_the_ears.asp

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