On 10/17/06 11:20 AM, in article
GcudnZoLYutAg6jYnZ2dnUVZ_qCdnZ2d@comcast.com, "Anonymous"
<alias@hidden.invalid> wrote:

I wish it was a cure. . This was presented in 04 and I haven't heard
anything further about it.

Murray Grossan, M.D.

Here is the cut-to-the-chase summary of this study of Botox T treatment
by yours truly:
"Results were both 'statistically significant' and also 'not
statistically significant'.  More studies recommended."

How about a different angle:  Botulinum toxin A injections may be a
benefit when given to treat facial wrinkles in that your new, younger
looking appearance may raise your general sense of well being and
happiness thereby providing a distraction from the T.  Just a thought.

====================
Results: Twenty-six patients completed both injections and all
follow-up and were included in data analysis. Following BOTOX®
treatment, subjective tinnitus changes included seven patients
improved, three worsened, and sixteen unchanged. Following placebo
treatment, two patients were improved, seven worsened, and seventeen
unchanged. Comparison of the treatment and placebo groups was
statistically significant (p<.005) when including better, worse, and
same effects. Results were not statistically significant evaluating the
better versus worse and unchanged effects combined. A significant
decrease in THI scores between pre-treatment and four month post BOTOX
injection (p=.0422) was recorded. None of the other comparisons of
pre-treatment - one month, or pretreatment - four months were
significantly different.

Conclusion: In this study, BOTOX® was used to treat a small number of
patients with tinnitus originating from a variety of causes. While the
results suggest a positive effect of BOTOX® on irritation from
tinnitus, the authors recommend a larger study to document repeatable
results prior to drawing definitive conclusions regarding the potential
benefits of BOTOX® in treatment of tinnitus.

Coincidentally there is a guy posting on the yahoo tinnitus group.  He
is participating in a clinical trial of botox shots to try to treat
tinnitus.   He is posting his experiences in the following thread.
Good reading.
http://health.groups.yahoo.com/group/Tinnitus/message/2520