Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / Diseases and Disorders / Tinnitus / September 2006

Tip: Looking for answers? Try searching our database.

Equitab??

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
Dave C. - 22 Aug 2006 19:44 GMT
I came across an ad for Equitab, a blend of "ginkgo extracts, dried rhizome
of ginger, kelp, and cayenne."  Reportly, good for tinnitus and vertigo.

I'm not rushing out to buy some, but any comments on this product?  Might be
just another herbal blend.

Signature

Dave C.

Susan - 22 Aug 2006 19:49 GMT
> I came across an ad for Equitab, a blend of "ginkgo extracts, dried rhizome
> of ginger, kelp, and cayenne."  Reportly, good for tinnitus and vertigo.
>
> I'm not rushing out to buy some, but any comments on this product?  Might be
> just another herbal blend.

That's a new one here, Dave.

If it isn't independently tested and certified, I'd worry about the
quality and quantity of the contents.

Susan
Dave C. - 22 Aug 2006 21:30 GMT
> x-no-archive: yes
>
[quoted text clipped - 11 lines]
>
> Susan

Thanks, Susan.  I am not excited about this at all.....but the word Equitab
sounded so impressive.  I personnally am not interested for reason that you
mentioned.

Dave
marrer - 22 Aug 2006 22:15 GMT
>> x-no-archive: yes
>>
[quoted text clipped - 17 lines]
>
> Dave

sounds like an insurance firm to me........:)
STEPHEN - 10 Sep 2006 14:32 GMT
your the prick that slags off disabled people, and you have tinnitus

I am very pleased to see you have a disablement yourself, as they say there
bit the grace of god go you. I hope you will never be cured after talking
badly about disabled people

Signature

" You three are a right pair
if I've ever seen one"

> >> x-no-archive: yes
> >>
[quoted text clipped - 19 lines]
> >
> sounds like an insurance firm to me........:)
marrer - 10 Sep 2006 21:30 GMT
> your the prick that slags off disabled people, and you have tinnitus
>
> I am very pleased to see you have a disablement yourself, as they say there
> bit the grace of god go you. I hope you will never be cured after talking
> badly about disabled people

proof please?
 and do stop stalking me across usenet,theres a good chap.
drfrank21@gmail.com - 22 Aug 2006 22:16 GMT
> > x-no-archive: yes
> >
[quoted text clipped - 4 lines]
> >> I'm not rushing out to buy some, but any comments on this product?  Might
> >> be just another herbal blend.

I'm always just a bit wary about ginkgo- not convinced that
the possible (and I mean possible) benefit is worth the risk of
possible serious side effects, notably hemorrhages (brain).
Granted the risks are small but they are present.

As for the kelp, cayenne and ginger- all are available at
any health food store and likely at a fraction of the cost
of their "formula". None of these, as far as I know have
any side effects and are safe to use.

One always has to be aware of the hype with these
products. But I personnaly wouldn't spend the money
on this product. Good luck with what your decision.

frank
Susan - 22 Aug 2006 22:22 GMT
> I'm always just a bit wary about ginkgo- not convinced that
> the possible (and I mean possible) benefit is worth the risk of
> possible serious side effects, notably hemorrhages (brain).
> Granted the risks are small but they are present.

Are you equally wary of oily fish, fish oil, aspirin, vitamin C and
garlic?

> As for the kelp, cayenne and ginger- all are available at
> any health food store and likely at a fraction of the cost
[quoted text clipped - 4 lines]
> products. But I personnaly wouldn't spend the money
> on this product. Good luck with what your decision.

Years ago, SMN posted an evaluation of Ginkgo products and said one in
particular, Ginkgold seemed to be well standardized and suggested that
those wanting to do a trial should perhaps use it.

Anything strong enough to help is strong enough to hurt if you're not
wise and informed.

Susan
drfrank21@gmail.com - 22 Aug 2006 22:41 GMT
> x-no-archive: yes
>
[quoted text clipped - 5 lines]
> Are you equally wary of oily fish, fish oil, aspirin, vitamin C and
> garlic?

I've never seen a retinal hemorrhage due to vit c/asa/fish oil
but I have with gingko. The bleeds weren't pleasant.
I've also have talked with physicians who have had patients
with cerebral hemorrhages due to ginkgo. I think most
experts would rank gingko over the above (ie vit c,asa)
with the greater side effect of hemorrhage
(assuming of course one doesnt take
a whole bottle of aspirin at one time).

The biggest side effect of fish oil is fish breath.

frank
Susan - 22 Aug 2006 23:14 GMT
> I've never seen a retinal hemorrhage due to vit c/asa/fish oil
> but I have with gingko. The bleeds weren't pleasant.

Are you 100% sure that the patient wasn't consuming any of the above, or
vitamin E, for that matter?  Or did they overdose on Ginkgo?  That's
very different than taking a well researched dose without other
contraindications.

> I've also have talked with physicians who have had patients
> with cerebral hemorrhages due to ginkgo. I think most
[quoted text clipped - 4 lines]
>
> The biggest side effect of fish oil is fish breath.

Not true, Frank, many folks detect easy bruising at even low doses.
I never get fish breath from it, but I notice that when I lance for my
blood glucose tests, it's hard to control the amount of blood as opposed
to how hard it is to get a droplet without fish oil.  In fact, it has
been associated with higher stroke incidence.  It's a powerful
antithrombotic.

No question that supplements should be taken with great caution and
research, just like meds and medical care, IMO.

Susan
Martin Smith - 22 Aug 2006 23:27 GMT
> x-no-archive: yes
>
[quoted text clipped - 16 lines]
>
> Not true, Frank, many folks detect easy bruising at even low doses.

It must be a genetic thing. Norwegians have eaten lots of fish oil for
ages, but they don't seem to bruise easily.

> I never get fish breath from it, but I notice that when I lance for my
> blood glucose tests, it's hard to control the amount of blood as opposed
> to how hard it is to get a droplet without fish oil.  In fact, it has
> been associated with higher stroke incidence.

Eating fish oil reduces the risk of stroke.

<http://www.mercola.com/2003/jan/8/fish_oil_stroke.htm>
<http://www.sciencedaily.com/releases/2001/01/010117075510.htm>

>It's a powerful antithrombotic.
>
> No question that supplements should be taken with great caution and
> research, just like meds and medical care, IMO.
>
> Susan
Jim Chinnis - 23 Aug 2006 02:30 GMT
Susan <nevermind@nomail.com> wrote in part:

>Not true, Frank, many folks detect easy bruising at even low doses.
>I never get fish breath from it, but I notice that when I lance for my
>blood glucose tests, it's hard to control the amount of blood as opposed
>to how hard it is to get a droplet without fish oil.  In fact, it has
>been associated with higher stroke incidence.  It's a powerful
>antithrombotic.

I take fish oil, and I've read most of the quality research literature. I
came to the conclusion that the antithrombotic effect is real but very
slight.

Not that it has anything to do with tinnitus.
Signature

Jim Chinnis / Warrenton, Virginia, USA
Want to discuss Meniere's? See http://groups.yahoo.com/group/MenieresDG

Susan - 23 Aug 2006 14:51 GMT
> I take fish oil, and I've read most of the quality research literature. I
> came to the conclusion that the antithrombotic effect is real but very
> slight.
>
> Not that it has anything to do with tinnitus.

I take it, too, and it's not a slight effect, even with only one
capsule, when I lance for bg tests.  My sister and others I've heard
from bruise with only one dose.

Susan
Martin Smith - 23 Aug 2006 15:00 GMT
> x-no-archive: yes
>
[quoted text clipped - 9 lines]
>
> Susan

I always thought bruising was caused by broken blood veins. Bruising
isn't caused by thin blood, is it?
drfrank21@gmail.com - 23 Aug 2006 18:10 GMT
> x-no-archive: yes
>
[quoted text clipped - 5 lines]
> very different than taking a well researched dose without other
> contraindications.

The only thing I'm 100% sure of is that I'll be dead one day.
So I can't say 100% that the bleeds were caused by the
gingko .The one guy I remember was taking the gingko for
memory loss. He couldn't remember how much he was taking
(there must be some irony in that) immediately up to
his episode.

> Not true, Frank, many folks detect easy bruising at even low doses.
> I never get fish breath from it, but I notice that when I lance for my
> blood glucose tests, it's hard to control the amount of blood as opposed
> to how hard it is to get a droplet without fish oil.  In fact, it has
> been associated with higher stroke incidence.  It's a powerful
> antithrombotic.

I've been taking 1000 mg of salmon oil (omega 3) for years on
advice from my internist who stated the benefits included lower
cholestorol/ldl levels as well as improved cardiovascular functioning
(lower incidence of heart attacks, strokes) as there is a very
strong family hx of heart disease in my family. May be a case
of dueling studies, I don't know.  Also been on 1000 mg of
vit c for many years (not a cold or uri in 10 yrs).

With that, I still think I'm at a much less risk for a cerebral
hemorrhage than on gingko. But I've heard of people dropping
over dead from a cva without any warning. When it's
your time to go, well.................

frank

frank
Susan - 23 Aug 2006 18:40 GMT
> The only thing I'm 100% sure of is that I'll be dead one day.
> So I can't say 100% that the bleeds were caused by the
> gingko .The one guy I remember was taking the gingko for
> memory loss. He couldn't remember how much he was taking
> (there must be some irony in that) immediately up to
> his episode.

He may have been confused enough to take too much, and may've failed to
report other supplements he took with it.

> I've been taking 1000 mg of salmon oil (omega 3) for years on
> advice from my internist who stated the benefits included lower
[quoted text clipped - 3 lines]
> of dueling studies, I don't know.  Also been on 1000 mg of
> vit c for many years (not a cold or uri in 10 yrs).

I haven't seen much on other than TGL lowering with fish oil, and
reduced inflammation.  You may be interested in the completely atoxic
stuff I take; lowered my LDL 70 points lickety split, saw an uptick in
my HDL to 70.  It had already doubled from a decade of 34 to 68 when I
switched to low carb diet.

[Evaluation of the cholesterol-lowering effectiveness of pantethine in
women in perimenopausal age]

[Article in Italian]

Binaghi P, Cellina G, Lo Cicero G, Bruschi F, Porcaro E, Penotti M.

Servizio di Cardiologia, Istitut Clinici di Perfezionamento, Milano.

Cardiovascular diseases are the main cause of death also in women. Their
incidence, rapidly growing in the peri-menopausal period, is related to
serum levels of total cholesterol and its LDL fraction. It was also
shown that the peroxidation of LDL is an additional factor in the
genesis of atherosclerotic vascular disease. As long-term treatments
with synthetic lipid-lowering drugs may cause undesirable side effects,
while pantethine is known to be well tolerated, we treated 24
hypercholesterolemic women (total serum cholesterol greater than or
equal to 240 mg/dl), in perimenopausal age (range: 45-55 years, mean +/-
SD = 51.6 +/- 2.4) with 900 mg/day of pantethine. This is a precursor of
coenzyme A, with an antiperoxidation effect in vivo, and our aim was to
confirm its lipid lowering activity in this particular type of patients.
After 16 weeks of treatment, significant reductions of total
cholesterol, LDL-cholesterol and LDL-C/HDL-C ratio could be observed. No
remarkable changes of the main laboratory parameters (fasting blood
sugar, B.U.N., creatinine, uric acid) were seen. Efficacy percentages of
the treatment were about 80%. None of the patients complained of adverse
reactions due to the treatment with pantethine. In conclusion, we
suggest that pantethine should be considered in the long-term treatment
of lipid derangements occurring in the perimenopausal age.

PMID: 2359503 [PubMed - indexed for MEDLINE]
1: Acta Biomed Ateneo Parmense. 1984;55(1):25-42.     Related Articles, Links

[Hyperlipidemia, diabetes and atherosclerosis: efficacy of treatment
with pantethine]

[Article in Italian]

Arsenio L, Caronna S, Lateana M, Magnati G, Strata A, Zammarchi G.

The hypolipidemizing effects of Pantethine were investigated by the
Authors in 37 hypercholesterolemic and/or hypertriglyceridemic patients.
Of these, 21 were also diabetic, in a satisfying glucidic compensation,
in order to verify the action of this drug also in this metabolic
condition. The study was carried out for three months and during this
period the patients were given Pantethine at the dose of 600 mg/die
orally. At the 30th, the 60th, the 90th day of treatment the following
parameters were controlled: cholesterolemia, HDL cholesterol,
apolipoproteins A and B, triglyceridemia, systolic and diastolic
arterial pressure, uricemia, body weight. Thirty days after suspending
the treatment, the parameters were controlled again to detect a possible
"rebound" effect. The results were analyzed on the whole case-record,
subdividing the patients in dislipidemic and diabetic-dislipidemic, and
on the basis of the Fredrickson's classification. Pantethine induced in
all groups a quick and progressive decrease of cholesterolemia,
triglyceridemia, LDL cholesterol and Apolipoproteins B with increased
HDL cholesterol and Apolipoproteins A. After suspending the treatment,
there is a clear inversion of the state of these parameters. The Authors
conclude that the present work shows that Pantethine, a natural and
atoxic substance, an important component of Coenzyme A, is efficacious
in determining a clear tendency towards normalization of the lipidic values.

PMID: 6232801 [PubMed - indexed for MEDLINE]
1: Atherosclerosis. 1984 Jan;50(1):73-83.     Related Articles, Links

Controlled evaluation of pantethine, a natural hypolipidemic compound,
in patients with different forms of hyperlipoproteinemia.

Gaddi A, Descovich GC, Noseda G, Fragiacomo C, Colombo L, Craveri A,
Montanari G, Sirtori CR.

Pantethine (P), the stable disulphate form of pantetheine, major
component and precursor of coenzyme A, was evaluated within a
double-blind protocol (8 weeks for P or for a corresponding placebo) in
29 patients, 11 with type IIB hyperlipoproteinemia, 15 with type IV, and
3 with an isolated reduction of high density lipoprotein cholesterol
(HDL-C) levels. In type IIB patients, P (300 mg t.i.d.) determined a
highly significant lowering of plasma total and low density lipoprotein
(LDL) associated cholesterol (-13.5% for both parameters). In the same
patients, HDL-C levels increased about 10% at the end of treatment.
Switching from P to placebo was associated with a rapid return to the
baseline cholesterolemia. Both in type IIB and type IV patients, plasma
triglyceride levels were reduced around 30%, when P was given as the
first treatment; when it was preceded by placebo, reductions were less
striking (respectively, -17.8% for type IIB and -13.0% for type IV, at
the end of P treatment). HDL-C levels were not increased by P, either in
type IV, and in the patients with low HDL cholesterolemia. In type IV,
LDL cholesterol levels showed a variable response to P: they tended to
increase when below 132 mg/dl, prior to treatment, and to be reduced
when above this level. This study provides evidence for a significant
hypocholesterolemic effect of P, a natural compound free of overt side
effects. It also indicates that P may raise HDL-C levels in type IIB
patients, while moderately reducing triglyceridemia.

Publication Types:
•    Clinical Trial
•    Controlled Clinical Trial

PMID: 6365107 [PubMed - indexed for MEDLINE]
1: Int J Clin Pharmacol Ther Toxicol. 1986 Nov;24(11):630-7.     Related
Articles, Links

Lipoprotein changes induced by pantethine in hyperlipoproteinemic
patients: adults and children.

Bertolini S, Donati C, Elicio N, Daga A, Cuzzolaro S, Marcenaro A,
Saturnino M, Balestreri R.

Following a brief outline of current knowledge concerning
atherosclerosis and its treatment, the authors describe the results
obtained by treating with pantethine (900-1200 mg daily for 3 to 6
months) a series of 7 children and 65 adults suffering from
hypercholesterolemia alone or associated with hypertriglyceridemia
(types IIa and IIb of Fredrickson's classification). Pantethine
treatment produced significant reduction of the better known risk
factors (total cholesterol, LDL-cholesterol, triglycerides, and apo-B)
and a significant increase of HDL-cholesterol (signally HDL2) and
apolipoprotein A-I. The authors conclude with a discussion of these
results and of the possible role of pantethine in the treatment of
hyperlipoproteinemia, in view of its perfect tolerability and
demonstrated therapeutic effectiveness.

PMID: 3098691 [PubMed - indexed for MEDLINE]
: Atherosclerosis. 1984 Dec;53(3):255-64.     Related Articles, Links

Pantethine reduces plasma cholesterol and the severity of arterial
lesions in experimental hypercholesterolemic rabbits.

Carrara P, Matturri L, Galbussera M, Lovati MR, Franceschini G, Sirtori CR.

Pantethine (P), a coenzyme A precursor, was administered to
cholesterol-fed rabbits (0.5% cholesterol diet + 1% pantethine) for 90
days. At the end of treatment, plasma total cholesterol levels were
reduced 64.7% and the HDL/total cholesterol ratio increased in P-treated
animals; a significant rise of the apo A-I/A-II ratio was detected in
HDL. VLDL lipid and protein levels were, on the other hand, reduced by
P. The cholesterol-ester content of both liver and aortic tissues was
not significantly affected by P. Although the total aortic area with
evident plaques was reduced only 18.2%, the microscopical examination of
sections from the major vessels of P-treated animals, showed a reduction
in the severity of lesions, both in the aorta and in the coronary
arteries. These findings suggest that P, in addition to significantly
lowering plasma cholesterol levels in rabbits on an experimental diet,
may modify lipid deposition in major arteries, possibly by affecting
lipoprotein composition and/or exerting an arterial protective effect.

PMID: 6442152 [PubMed - indexed for MEDLINE]
Clin Ther. 1986;8(5):537-45.     Related Articles, Links

Effectiveness of long-term treatment with pantethine in patients with
dyslipidemia.

Arsenio L, Bodria P, Magnati G, Strata A, Trovato R.

A one-year clinical trial with pantethine was conducted in 24 patients
with established dyslipidemia of Fredrickson's types II A, II B, and IV,
alone or associated with diabetes mellitus. The treatment was well
tolerated by all patients with no subjective complaints or detectable
side effects. Blood lipid assays repeated after 1, 3, 6, 9, and 12
months of treatment revealed consistent and statistically significant
reductions of all atherogenic lipid fractions (total cholesterol,
low-density lipoprotein cholesterol, and apolipoprotein B) with parallel
increases of high-density lipoprotein cholesterol and apolipoprotein A.
The results were equally good in patients with uncomplicated
dyslipidemia and in those with associated diabetes mellitus. The authors
conclude that pantethine (a drug entity related to the natural compound,
pantetheine) represents a valid therapeutic support for patients with
dyslipidemia not amenable to satisfactory correction of blood lipids by
diet alone.

PMID: 3094958 [PubMed - indexed for MEDLINE]
Acta Biomed Ateneo Parmense. 1987;58(5-6):143-52.     Related Articles, Links

[Clinical use of pantethine by parenteral route in the treatment of
hyperlipidemia]

[Article in Italian]

Arsenio L, Bodria P, Bossi S, Lateana M, Strata A.

Servizio di Malattie del Ricambio e Diabetologia, Ospedali Riuniti, Parma.

Recent investigations have confirmed the effectiveness and the excellent
tolerability of pantethine, a derivative of pantetheine, an essential
part of the acetylation coenzyme CoA, administered P.O., in normalizing
the blood lipid concentrations of patients with hyperlipidemias. A group
of 18 patients with hyperlipidemias (9 M, 9 F), with an average age of
52.6 years, was submitted to pantethine parenteral treatment. After a 20
days wash-out, pantethine (400 mg/day; BID) was administered
intramuscularly, for 20 days. Total cholesterol, triglycerides,
HDL-cholesterol, apo A-1 and B lipoprotein, uric acid in serum,
glycemia, CBC, B.U.N., creatininemia, E.S.R., SGOT, SGPT, bilirubinemia,
cardiac frequency, blood pressure and body weight were controlled before
and after treatment. The drug showed to have a therapeutic effectiveness
by a rapid and significant improvement in the blood lipid pattern with
reduction of total cholesterol, triglycerides and apo-B lipoprotein and
increase of HDL-cholesterol and apo A-1 lipoprotein. The tolerability of
pantethine at the stated dosage and mode of administration was
invariably excellent, with non complaints or visible side effects
imputable to the test drug. BUN, creatininemia, glycemia, SGOT, SGPT,
bilirubinemia, E.S.R., CBC, cardiac frequency and blood pressure
readings showed no noteworthy changes throughout the study.

PMID: 2970754 [PubMed - indexed for MEDLINE]

1: Vopr Pitan. 1987 Mar-Apr;(2):15-7.     Related Articles, Links

[Therapeutic efficacy of pantothenic acid preparations in ischemic heart
disease patients]

[Article in Russian]

Borets VM, Lis MA, Pyrochkin VM, Kishkovich VP, Butkevich ND.

The therapeutic effectiveness of the pantothenic acid drugs:
calciipantothenas and pantethine, was studied in 182 patients with
coronary heart disease and stable angina of effort. It is shown that
both the drugs produce favourable effects on certain parameters of
hemodynamics, on the metabolism of lipids, riboflavin and ascorbic acid.
It is recommended that the administration of calciipantothenas in a dose
of 300 mg/day, during 3 weeks, be included into the combined treatment
of coronary patients with no manifest disorders of lipid metabolism.
Patients with manifest hyperlipidemia should be administered pantethine
in a dose of 500 mg/day.

PMID: 3590676 [PubMed - indexed for MEDLINE]

1: Clin Nephrol. 1986 Feb;25(2):70-4.     Related Articles, Links

Pantethine improves the lipid abnormalities of chronic hemodialysis
patients: results of a multicenter clinical trial.

Donati C, Barbi G, Cairo G, Prati GF, Degli Esposti E.

In the course of a post-marketing surveillance program on the
effectiveness and tolerability of pantethine in the treatment of
hyperlipidemia, the effects of the drug were explored in 31 patients
with dyslipidemia undergoing chronic hemodialysis. The mean duration of
treatment was 9 months (min. 7 months, max. 24 months), with oral doses
of 600 to 1200 mg of pantethine daily (mean daily dosage 970 mg).
Improvement was noted in terms of total blood cholesterol in the 7
patients with basal hypercholesterolemia (p less than 0.01) and highly
significant reduction of serum triglycerides. No variations of
HDL-cholesterol or total Apo-A were detected. None of the patients
experienced any adverse effects from the treatment. In the light of
extensive experience with the drug, plus the results of this study, the
authors conclude by stressing the importance of an effective and readily
tolerated product, such as pantethine, for the treatment of dyslipidemia
in patients on chronic hemodialysis.

Publication Types:
•    Clinical Trial

PMID: 3516477 [PubMed - indexed for MEDLINE]
1: Artery. 1987;15(1):1-12.     Related Articles, Links

Lowering effect of pantethine on plasma beta-thromboglobulin and lipids
in diabetes mellitus.

Eto M, Watanabe K, Chonan N, Ishii K.

Second Department of Internal Medicine, Asahikawa Medical College, Japan.

Pantethine in a dosage of 600 mg for the first 3 months, and in a dosage
of 1200 mg for the second 6 months was given to 16 diabetics in whom
plasma beta-thromboglobulin was raised (greater than 50 ng/ml). Plasma
beta-TG levels decreased significantly with pantethine treatment for 9
months. Plasma triglyceride, total cholesterol, apo E and apo CII levels
decreased significantly after 9 months. Plasma LDL-C and atherogenic
index (LDL-C/HDL-C ratio or apo B/apo AI ratio) tended to decrease with
treatment. It is concluded that administration of pantethine may be
beneficial in the prevention of diabetic angiopathy because of its
lowering effect on plasma beta-TG, lipids and apolipoproteins.

PMID: 2963604 [PubMed - indexed for MEDLINE]
1: Ter Arkh. 1991;63(11):58-60.     Related Articles, Links

[The use of pantothenic acid preparations in treating patients with
viral hepatitis A]

[Article in Russian]

Komar VI.

Calcium pantothemate in the daily dose 300 mg and 600 mg and pantetheine
in the dose 90 mg and 180 mg per os were applied for 3-4 weeks in
combined therapy of 156 patients with viral hepatitis A. In addition to
the positive clinico-biochemical effect, these drugs produced an
immunomodulatory action and a beneficial effect on the level of blood
serum immunoglobulins and the phagocytic activity of peripheral blood
neutrophils. Pantetheine provided the most pronounced therapeutic effect.

PMID: 1810066 [PubMed - indexed for MEDLINE]
1: Clin Ter. 1989 Mar 31;128(6):411-22.     Related Articles, Links

[Pantethine, diabetes mellitus and atherosclerosis. Clinical study of
1045 patients]

[Article in Italian]

Donati C, Bertieri RS, Barbi G.

After a review of the clinical studies on the treatment of diabetic
patients with pantethine, the authors discuss the results obtained in a
postmarketing surveillance (PMS) study on 1045 hyperlipidemic patients
receiving pantethine (900 mg/day on average). Of these patients, 57 were
insulin-dependent (Type I) and 241 were non insulin-dependent (Type II)
diabetics. Beyond the epidemiological considerations made possible by a
PMS study, the authors show that pantethine brought about a
statistically significant and comparable improvement of lipid metabolism
in the three groups of patients, with very good tolerability. Pantethine
should therefore be considered for the treatment of lipid abnormalities
also in patients at risk such as those with diabetes mellitus.

PMID: 2524328 [PubMed - indexed for MEDLINE]
1: Vopr Pitan. 1983;(1):45-9.     Related Articles, Links

[Pantothenic acid metabolic disorder and its relation to the change in
energy processes in patients with ischemic heart disease and hypertension]

[Article in Russian]

Borets VM, Ovchinnikov VA, Mironchik VV, Moiseenok AG, Lis MA.

Pantothenic acid metabolism and the status of energy processes in
leukocytes were examined in 171 patients with hypertension and coronary
heart disease. It was shown that the patients' body supply with the
vitamin decreased as the disease progressed and heart failure
supervened. The deficiency of pantothenic acid was shown to be
interrelated with the impairment of energy processes. Application of
pantothenate in a dose of 200 mg a day for two weeks led to the
increased content of pantothenic acid and to normalization of energy
processes.

PMID: 6837001 [PubMed - indexed for MEDLINE]
1: Angiology. 1987 Mar;38(3):241-7.     Related Articles, Links

Effect of oral treatment with pantethine on platelet and plasma
phospholipids in IIa hyperlipoproteinemia.

Prisco D, Rogasi PG, Matucci M, Paniccia R, Abbate R, Gensini GF, Neri
Serneri GG.

In a single-blind, crossover, completely randomized study, the effects
of oral treatment with pantethine or placebo on fatty acid composition
of plasma and platelet phospholipids were investigated in 10 IIa
hyperlipoproteinemic patients. A significant decrease of total
cholesterol and total phospholipids was observed both in plasma and in
platelets after a twenty-eight-day treatment. In plasma, pantethine
induced a decrease of the ratio sphingomyelin/phosphatidylcholine.
Moreover, a relative increase of n3-polyunsaturated fatty acids both in
plasma and in platelet phospholipids and a decrease of arachidonic acid
in plasma phospholipids were observed. These results indicate that
pantethine can affect plasma and platelet lipid composition with
possibly favorable influences on the determinants of cell membrane fluidity.

Publication Types:
•    Clinical Trial
•    Randomized Controlled Trial

PMID: 3551695 [PubMed - indexed for MEDLINE]

> With that, I still think I'm at a much less risk for a cerebral
> hemorrhage than on gingko. But I've heard of people dropping
> over dead from a cva without any warning. When it's
> your time to go, well.................

Lots of those folks drop dead with "normal" cholesterol levels.  Keep an
eye on the TGL and HDL for better risk prediction:

Ann Epidemiol. 2005 May;15(5):405-13.
Related Articles,   Links

A comparison of lipid variables as predictors of cardiovascular disease
in the Asia Pacific region.

Barzi F, Patel A, Woodward M, Lawes CM, Ohkubo T, Gu D, Lam TH, Ueshima
H; Asia Pacific Cohort Studies Collaboration.

The George Institute for International Health, University of Sydney,
Camperdown, NSW 2050, Australia. fbarzi@thegeorgeinstitute.org

PURPOSE: Many guidelines advocate measurement of total or low density
lipoprotein cholesterol (LDL), high density lipoprotein cholesterol
(HDL), and triglycerides (TG) to determine treatment recommendations for
preventing coronary heart disease (CHD) and cardiovascular disease
(CVD). This analysis is a comparison of lipid variables as predictors of
cardiovascular disease. METHODS: Hazard ratios for coronary and
cardiovascular deaths by fourths of total cholesterol (TC), LDL, HDL,
TG, non-HDL, TC/HDL, and TG/HDL values, and for a one standard deviation
change in these variables, were derived in an individual participant
data meta-analysis of 32 cohort studies conducted in the Asia-Pacific
region. The predictive value of each lipid variable was assessed using
the likelihood ratio statistic. RESULTS: Adjusting for confounders and
regression dilution, each lipid variable had a positive (negative for
HDL) log-linear association with fatal CHD and CVD. Individuals in the
highest fourth of each lipid variable had approximately twice the risk
of CHD compared with those with lowest levels. TG and HDL were each
better predictors of CHD and CVD risk compared with TC alone, with test
statistics similar to TC/HDL and TG/HDL ratios. Calculated LDL was a
relatively poor predictor. CONCLUSIONS: While LDL reduction remains the
main target of intervention for lipid-lowering, these data support the
potential use of TG or lipid ratios for CHD risk prediction.

PMID: 15840555 [PubMed - indexed for MEDLINE]

Susan
drfrank21@gmail.com - 23 Aug 2006 19:52 GMT
> I haven't seen much on other than TGL lowering with fish oil, and
> reduced inflammation.  You may be interested in the completely atoxic
> stuff I take; lowered my LDL 70 points lickety split, saw an uptick in
> my HDL to 70.  It had already doubled from a decade of 34 to 68 when I
> switched to low carb diet.

I'm kind of lucky that my current trig is 25 and total chol is
120 so I'm taking the salmon oil for the other benefits.I guess
I do low carb as well (not Atkins or anything like that)
in that I don't eat any sweets, bread, pasta etc. but
mainly eat salads, fish and poultry. The only thing
I'd like to do would be to increase my HDL levels.

frank
Susan - 23 Aug 2006 20:50 GMT
> I'm kind of lucky that my current trig is 25 and total chol is
> 120 so I'm taking the salmon oil for the other benefits.

Lucky, or medicated?

I guess
> I do low carb as well (not Atkins or anything like that)
> in that I don't eat any sweets, bread, pasta etc. but
> mainly eat salads, fish and poultry. The only thing
> I'd like to do would be to increase my HDL levels.

That is like Atkins, FYI.  To a T.  Just not the Atkins that opponents
like you to think it is.

Susan
drfrank21@gmail.com - 23 Aug 2006 23:08 GMT
> x-no-archive: Yes
>
> > I'm kind of lucky that my current trig is 25 and total chol is
> > 120 so I'm taking the salmon oil for the other benefits.
>
> Lucky, or medicated?

Lucky I guess (the only "meds" I'm taking for this would be
the omega-3).

> > I do low carb as well (not Atkins or anything like that)
> > in that I don't eat any sweets, bread, pasta etc. but
[quoted text clipped - 5 lines]
>
> Susan

Please don''t assume or presume anything. I think Atkins got
it right with the low carb lifestyle. If anything, I'm a
proponent and I've been on low carb long before the
Atkins craze hit. But I did it intuitively and before I
knew much about Atkins or his diet. It was interesting
to see all the backlash when it was in full swing.
Sure was polarizing.

But I've had people tell me I'm not on Atkins because of all
the vegetables I eat but I think it's all semantics.

frank
Janice - 24 Aug 2006 00:55 GMT
Some feel most of the results from Atkins and similar diets was not
from the low carb effect as much as the low gluten or low grain
intake. This is slowly becoming apparent to many.

Carbs are a necessary part of human intake and humans do not survive
well without them. We just have to pick better carbs.

>> Please don''t assume or presume anything. I think Atkins got
> it right with the low carb lifestyle. If anything, I'm a
[quoted text clipped - 8 lines]
>
> frank
Susan - 24 Aug 2006 04:05 GMT
> Some feel most of the results from Atkins and similar diets was not
> from the low carb effect as much as the low gluten or low grain
> intake. This is slowly becoming apparent to many.

No, it's the hormones.  Insulin promotes inflammation and atherogenesis.

> Carbs are a necessary part of human intake and humans do not survive
> well without them. We just have to pick better carbs.

There is absolutely no essential carbohydrate in human nutrition,
biologically, only essential fats and proteins.  Without those you die,
without carbs, you live.  Humans survive just fine, even better without
carbs, particularly all starches.

Susan
Martin Smith - 24 Aug 2006 07:22 GMT
> x-no-archive: yes
>
[quoted text clipped - 9 lines]
> There is absolutely no essential carbohydrate in human nutrition,
> biologically,

That depends on how active you are. If you burn a lot of energy during
the day, because of training or other strenuous activity, you have to
consume carbohydrates. Primitive man, who was quite active, did consume
carbohydrates.

> only essential fats and proteins.  Without those you die,
> without carbs, you live.  Humans survive just fine, even better without
> carbs, particularly all starches.
>
> Susan
Susan - 24 Aug 2006 12:26 GMT
> That depends on how active you are. If you burn a lot of energy during
> the day, because of training or other strenuous activity, you have to
> consume carbohydrates. Primitive man, who was quite active, did consume
> carbohydrates.

Good research with high performance athletes shows that to be false.
Even if it were true, one could avoid dietary carbs and just use a
dextrose sports drink during a workout.

Susan
Martin Smith - 24 Aug 2006 13:32 GMT
> x-no-archive: yes
>
[quoted text clipped - 4 lines]
>
> Good research with high performance athletes shows that to be false.

I don't think research shows that to be false. It depends on the amount,
frequency, and type of training. Nor are carbohydrates bad for you.
Human beings have always eaten carbohydrates. Refined sugar is bad for
you, and refined flour, but carbohydrates in general are healthy.

> Even if it were true, one could avoid dietary carbs and just use a
> dextrose sports drink during a workout.

Dextrose is a carbohydrate. If you eat it, it is a dietary carbohydrate.
Susan - 24 Aug 2006 13:57 GMT
x-no-archive: yesMetabolism. 1983 Aug;32(8):769-76.     Related
Articles, Links

    The human metabolic response to chronic ketosis without caloric
restriction: preservation of submaximal exercise capability with
reduced carbohydrate oxidation.

    Phinney SD, Bistrian BR, Evans WJ, Gervino E, Blackburn GL.

    To study the effect of chronic ketosis on exercise performance in
endurance-trained humans, five well-trained cyclists were fed a
eucaloric balanced diet (EBD) for one week providing 35-50 kcal/kg/d,
1.75 g protein/kg/d and the remainder of kilocalories as two-thirds
carbohydrate (CHO) and one-third fat. This was followed by four weeks
of a eucaloric ketogenic diet (EKD), isocaloric and isonitrogenous
with the EBD but providing less than 20 g CHO daily. Both diets were
appropriately supplemented to meet the recommended daily allowances
for vitamins and minerals. Pedal ergometer testing of maximal oxygen
uptake (VO2max) was unchanged between the control week (EBD-1) and
week 3 of the ketogenic diet (EKD-3). The mean ergometer endurance
time for continuous exercise to exhaustion (ENDUR) at 62%-64% of
VO2max was 147 minutes at EBD-1 and 151 minutes at EKD-4. The ENDUR
steady-state RQ dropped from 0.83 to 0.72 (P less than 0.01) from
EBD-1 to EKD-4. In agreement with this were a three-fold drop in
glucose oxidation (from 15.1 to 5.1 mg/kg/min, P less than 0.05) and a
four-fold reduction in muscle glycogen use (0.61 to 0.13 mmol/kg/min,
P less than 0.01). Neither clinical nor biochemical evidence of
hypoglycemia was observed during ENDUR at EKD-4. These results
indicate that aerobic endurance exercise by well-trained cyclists was
not compromised by four weeks of ketosis. This was accomplished by a
dramatic physiologic adaptation that conserved limited carbohydrate
stores (both glucose and muscle glycogen) and made fat the predominant
muscle substrate at this submaximal power level.

    PMID: 6865776 [PubMed - indexed for MEDLINE]

> I don't think research shows that to be false. It depends on the amount,
> frequency, and type of training. Nor are carbohydrates bad for you.
> Human beings have always eaten carbohydrates. Refined sugar is bad for
> you, and refined flour, but carbohydrates in general are healthy.
Martin Smith - 24 Aug 2006 14:37 GMT
Like I said, it depends on the nature and intensity of the training.

1. The subjects were already "well-trained."

2. They were all cyclists, who use primarily the big muscles in the legs.

3. They did the exercise to exhaustion test. That's only one kind of
training.

4. The experiment studied the effects on endurance-trained athletes, not
sprinters.

5. The conclusion applies to "aerobic endurance exercise by well-trained
cyclists."

6. To achieve this result, which is specific to ENDURANCE training,
these athletes had to undergo "a dramatic physiologic adaptation that
conserved limited carbohydrate stores (both glucose and muscle glycogen)
and made fat the predominant muscle substrate AT THIS SUBMAXIMAL POWER
LEVEL." [emphasis mine]

> x-no-archive: yesMetabolism. 1983 Aug;32(8):769-76.     Related
> Articles, Links
[quoted text clipped - 36 lines]
> > Human beings have always eaten carbohydrates. Refined sugar is bad for
> > you, and refined flour, but carbohydrates in general are healthy.
Susan - 24 Aug 2006 15:02 GMT
> Like I said, it depends on the nature and intensity of the training.
>
[quoted text clipped - 16 lines]
> and made fat the predominant muscle substrate AT THIS SUBMAXIMAL POWER
> LEVEL." [emphasis mine]

Just what I expected; thinking rooted in cement.

Bye.

Susan
Martin Smith - 24 Aug 2006 15:17 GMT
> x-no-archive: yes
>
[quoted text clipped - 20 lines]
>
> Just what I expected; thinking rooted in cement.

Yes, indeed. Your thinking is rooted in cement. You tried to apply the
specific result of this narrowly defined experiment to training in
general. You can't legitimately do that. Sprint training is far
different from endurance training. Upper body training, as in swimming,
is far different from lower body training, as in cycling. The conclusion
of the experiment does not disagree with what I said. It disagrees with
what you said.

I've done the Atkins diet. I am an athlete. I have spoken to other
athletes who have used low-carb diets. Every athlete I speak to about
this subject says their performance was adversely affected. But I
normally talk to swimmers. Swimming is an upper body exercise.

The Atkins diet is effective for losing weight.
Janice - 24 Aug 2006 22:47 GMT
Ony temporarily. The diet cannot be maintained due to health problems
and the weight returns faster than any other method I have seen.

> In article <4l5pr1Fcs77U1@individual.net>, Susan
> <nevermind@nomail.com>
> wrote:

> The Atkins diet is effective for losing weight.
Martin Smith - 24 Aug 2006 23:22 GMT
> Ony temporarily. The diet cannot be maintained due to health problems
> and the weight returns faster than any other method I have seen.

There is no such thing as permanent weight loss, so, temporarily, of
course. And the weight returning has nothing to do with the way it was
taken off. Obviously, if you return to the eating habits and lack of
exercise that made you blimp in the first place, you will blimp out
again. The diet works for losing weight. That's all it is supposed to do.

> > In article <4l5pr1Fcs77U1@individual.net>, Susan
> > <nevermind@nomail.com>
> > wrote:
>
> > The Atkins diet is effective for losing weight.
Janice - 25 Aug 2006 04:01 GMT
Not ture. Diets that teach good eating habits tend to last longer than
diets that do not. Low carb diets teach nothing except less hunger due
to more protein intake. Ex LC dieters do gain the weight back faster
from the several dozen cases I have seen and they all admit it.

>> Ony temporarily. The diet cannot be maintained due to health
>> problems
[quoted text clipped - 13 lines]
>>
>> > The Atkins diet is effective for losing weight.
Martin Smith - 25 Aug 2006 12:28 GMT
> Not ture. Diets that teach good eating habits tend to last longer than
> diets that do not.

Obviously true but irrelevant. The claim was that the Atkins diet is
effective for LOSING WEIGHT.

Furthermore, The the final stage of the Atkins diet is based on good
eating habits, completely in line with your definition of good eating
habits.

> Low carb diets teach nothing except less hunger due
> to more protein intake. Ex LC dieters do gain the weight back faster
> from the several dozen cases I have seen and they all admit it.

Nope. That's false. Read the specification for the Atkins diet. The diet
doesn't require more protein intake. It requires a higher percentage of
protein intake, as well as fat intake - for LOSING WEIGHT. Carbohydrates
are gradually increased, thus lowering the percentages of protein and
fat again, until weight loss stops and weight does not rise. In the
final, ongoing stage, only high glycemic sugars are disallowed, which
they should be anyway, since they provide nothing but calories.

And stop top posting.

> >> Ony temporarily. The diet cannot be maintained due to health
> >> problems
[quoted text clipped - 13 lines]
> >>
> >> > The Atkins diet is effective for losing weight.
Janice - 28 Aug 2006 04:16 GMT
All your retorts are only quoting the Atkin's theories and have no
basis of testing. Many of these have been disproven or disqualified.
Many scientifically based tests have been completed to find out how it
works and the fats were just wrong and a health hazard.  The increased
protein intake was the key.

The end result was that LC dieters ate less calories in controlled
testing.

I can read either style of posting. Stop bitching as a distraction.

>> Not ture. Diets that teach good eating habits tend to last longer
>> than
[quoted text clipped - 50 lines]
>> >>
>> >> > The Atkins diet is effective for losing weight.
Martin Smith - 28 Aug 2006 13:49 GMT
> All your retorts are only quoting the Atkin's theories and have no
> basis of testing.

Actually, I haven't quoted any Atkins material at all.

> Many of these have been disproven or disqualified.

Nothing I have said has been disproved or disqualified.

> Many scientifically based tests have been completed to find out how it
> works and the fats were just wrong and a health hazard.  The increased
> protein intake was the key.

There isn't any absolute increase in fat. It is a percentage increase,
and there is nothing unhealthy about it unless you were already eating
too much fat.

> The end result was that LC dieters ate less calories in controlled
> testing.

That's right. Or they increased exercise. Or both. and they increased
intake of water. And they eliminated refined sugar and white flour
entirely. And they increased fiber. And they used a vitamin supplement.
That's the diet, and it works for losing weight.

> I can read either style of posting. Stop bitching as a distraction.

Take your own advice.

> >> Not ture. Diets that teach good eating habits tend to last longer
> >> than
[quoted text clipped - 50 lines]
> >> >>
> >> >> > The Atkins diet is effective for losing weight.
Janice - 29 Aug 2006 00:47 GMT
Buh bye now.

>> All your retorts are only quoting the Atkin's theories and have no
>> basis of testing.
[quoted text clipped - 96 lines]
>> >> >>
>> >> >> > The Atkins diet is effective for losing weight.
Susan - 24 Aug 2006 04:02 GMT
> Lucky I guess (the only "meds" I'm taking for this would be
> the omega-3).

Cool beanz!  Low carbing really helps with lipids, too.

> Please don''t assume or presume anything. I think Atkins got
> it right with the low carb lifestyle. If anything, I'm a
[quoted text clipped - 3 lines]
> to see all the backlash when it was in full swing.
> Sure was polarizing.

Sure was.  I wasn't presuming anything, just addressing a common
misconception about Atkins.  I don't follow his or anyone's plan.

> But I've had people tell me I'm not on Atkins because of all
> the vegetables I eat but I think it's all semantics.

Yet low carbers eat more vegetables than anyone, and that includes the
Atkins diet.  You have to replace all those calorie dense, nutritionally
impoverished starches with something besides olive oil.  :-)

Susan
Martin Smith - 24 Aug 2006 07:24 GMT
> x-no-archive: yes
>
[quoted text clipped - 20 lines]
> Atkins diet.  You have to replace all those calorie dense, nutritionally
> impoverished starches with something besides olive oil.  :-)

But you just said you have no need to eat carbohydrates.
Jim Chinnis - 23 Aug 2006 23:54 GMT
drfrank21@gmail.com wrote in part:

>I'm kind of lucky that my current trig is 25 and total chol is
>120 so I'm taking the salmon oil for the other benefits.I guess
>I do low carb as well (not Atkins or anything like that)
>in that I don't eat any sweets, bread, pasta etc. but
>mainly eat salads, fish and poultry. The only thing
>I'd like to do would be to increase my HDL levels.

Do you eat enough fat? I know that increasing the monosaturated fat can
boost HDL. I've kept records for a while. My HDL was very low on a high carb
low fat diet. Reducing the carbs (or maybe the high-glycemic carbs) helped
me, but shifting fats to be heavy on monosaturates helped even more. I'm
talking about olive oil, avocados, almonds, etc.

Off-topic, I guess...
Signature

Jim Chinnis / Warrenton, Virginia, USA
Want to discuss Meniere's? See http://groups.yahoo.com/group/MenieresDG

drfrank21@gmail.com - 24 Aug 2006 01:17 GMT
> drfrank21@gmail.com wrote in part:
>
[quoted text clipped - 13 lines]
> Off-topic, I guess...
> --

I'll have a snack of peanuts/cashews (very easy to overeat these)
and peanut butter at times. I'm not sure how much is in
a hard-boiled egg but I try to stay away from bacon/sausage
because of the high nitrates. So I'm not sure just how much
I get in my diet.

frank
Susan - 24 Aug 2006 04:08 GMT
> I'll have a snack of peanuts/cashews (very easy to overeat these)
> and peanut butter at times.

I count ten almonds or pistachios out, close the container and that's
IT.  It is too easy to overdo those.  I'll have one TBS of PB or Almond
butter on occasion for a between meal snack.

 I'm not sure how much is in
> a hard-boiled egg but I try to stay away from bacon/sausage
> because of the high nitrates. So I'm not sure just how much
> I get in my diet.

I buy only grass fed meat products, no nitrates, healthy fat profiles.
The pork bacon I eat is naturally lean, dry rubbed and not cured.  I
never buy cured meats.

Susan
Eva Quesnell - 24 Aug 2006 15:49 GMT
>> drfrank21@gmail.com wrote in part:
>>
[quoted text clipped - 21 lines]
>
> frank

Walnuts and almonds are actually better choices for nuts.  :)

Eva
Susan - 24 Aug 2006 16:11 GMT
> Walnuts and almonds are actually better choices for nuts.  :)
>
> Eva

they are, but if one is eating low carb, the distinction becomes less
critical.  personal taste matters, too.

I limit PB due to aflatoxins and lectins, plus they're not really nuts.
But walnuts are no better, really, than almonds, hazelnuts, brazil nuts
or macadamias.

Susan
Eva Quesnell - 24 Aug 2006 21:34 GMT
> x-no-archive: yes
>
[quoted text clipped - 4 lines]
> they are, but if one is eating low carb, the distinction becomes less
> critical.  personal taste matters, too.

That's interesting.  I don't know a whole lot about it.  But it's just
what I've heard that almonds and walnuts are the best.

> I limit PB due to aflatoxins and lectins, plus they're not really nuts.
> But walnuts are no better, really, than almonds, hazelnuts, brazil nuts or
> macadamias.
>
> Susan

Of course, my problem would be eating way too many of them.

Eva
Susan - 24 Aug 2006 22:20 GMT
> Of course, my problem would be eating way too many of them.

The key is to count them out, close the bag and put it away.  :-)

Susan
Martin Smith - 24 Aug 2006 23:23 GMT
> x-no-archive: yes
>
> > Of course, my problem would be eating way too many of them.
>
> The key is to count them out, close the bag and put it away.  :-)

Or do more exercise.
Eva Quesnell - 24 Aug 2006 23:40 GMT
> x-no-archive: yes
>
[quoted text clipped - 3 lines]
>
> Susan

But that would involve willpower.  :-0

Eva
Susan - 25 Aug 2006 00:18 GMT
> But that would involve willpower.  :-0
>
> Eva

Not if you eat low carb.  Diminishes hunger and cravings.

I'm type 2 DM, so it's not wise to use food for recreation.  :-)

Susan
Dave C. - 23 Aug 2006 21:34 GMT
>> x-no-archive: yes
>>
[quoted text clipped - 36 lines]
>
> frank

I have been taking 1000mg fish oil and my HDL went up 25%.  I first started
taking GNC fish oil and had a fish taste from it.  Switched to Nordic
Naturals Omega-3 fish oils and haveno fish oil after taste.

Dave C.
Susan - 23 Aug 2006 22:02 GMT
> I have been taking 1000mg fish oil and my HDL went up 25%.  I first started
> taking GNC fish oil and had a fish taste from it.  Switched to Nordic
> Naturals Omega-3 fish oils and haveno fish oil after taste.

Is that the only change you've made?  I ask because that's a very low
dose and because that's not a typical effect.  But if it works for you,
who cares what's typical!

Susan
Dave C. - 24 Aug 2006 01:18 GMT
> x-no-archive: yes
>
[quoted text clipped - 7 lines]
>
> Susan

Hi, more specifically, I take 1000mg fish oil twice a day and this was over
a six month period.  As far as any other change, none that I am aware of,
but I reduced my simple sugars very drastically also.

As my doctor suggested, I lost 15 lbs (from 195 to 180 lbs) in order to get
my blood pressure under better control and I did that......probably was a
factor too.

Dave C.
Jim Chinnis - 24 Aug 2006 02:05 GMT
"Dave C." <myaddress.net> wrote in part:

>> x-no-archive: yes
>>
[quoted text clipped - 11 lines]
>a six month period.  As far as any other change, none that I am aware of,
>but I reduced my simple sugars very drastically also.

Reducing high-glycemic carbs (not restricted to simple sugars)  will reduce
triglycerides a lot and in some people it boosts HDL.

>As my doctor suggested, I lost 15 lbs (from 195 to 180 lbs) in order to get
>my blood pressure under better control and I did that......probably was a
>factor too.

Probably the main factor!

(Congrats!)
Signature

Jim Chinnis / Warrenton, Virginia, USA
Want to discuss Meniere's? See http://groups.yahoo.com/group/MenieresDG

Murray Grossan - 24 Aug 2006 04:44 GMT
On 8/23/06 10:10 AM, in article
1156353059.817505.271140@m79g2000cwm.googlegroups.com, "drfrank21@gmail.com"

>> x-no-archive: yes
>>
[quoted text clipped - 36 lines]
>
> frank

The bleeding from Gingko is rarely from the Gingko itself, it is the
combination with other products that is the usual cause. If we could
guarantee that persons on Gingko would never mix with salicylates, etc that
would be fine. But with persons taking pills by the handful, often not
knowing what the heck is in it - "Its Safe, its a Chinese Herb", I don't
know what's in it but its safe, its natural - then you can have a lethal
combination.
Skycloud - 25 Aug 2006 22:08 GMT
>> I've never seen a retinal hemorrhage due to vit c/asa/fish oil
> but I have with gingko. The bleeds weren't pleasant.
> I've also have talked with physicians who have had patients
> with cerebral hemorrhages due to ginkgo. I think most
> experts would rank gingko over the above (ie vit c,asa)
> with the greater side effect of hemorrhage

I shall always be grateful to Murray Grossan, in this ng,  for warning me
off ginkgo when I reported nose bleeds - before it was too late. Thanks
Murray!  ;)

Anybody using Ginkgo should be very careful IMO.

Steve
Susan - 25 Aug 2006 23:43 GMT
> I shall always be grateful to Murray Grossan, in this ng,  for warning me
> off ginkgo when I reported nose bleeds - before it was too late. Thanks
> Murray!  ;)
>
> Anybody using Ginkgo should be very careful IMO.

Anybody using *anything* should be very careful.

As Murray posted the other day, he's never seen a case where it was just
the ginkgo, it was the combination of ginkgo with other anti thrombotics.

Susan
Skycloud - 27 Aug 2006 22:02 GMT
--
> x-no-archive: yes
>
> As Murray posted the other day, he's never seen a case where it was just
> the ginkgo, it was the combination of ginkgo with other anti thrombotics.
>
> Susan

You make a fair point Susan. Though personally I wouldn't  want to take the
risk now since my ¼ aspirin-a-day regime is more effective on the T than the
Ginkgo and much cheaper too.  And I no longer get the nosebleeds...

Steve
fyfpoon@gmail.com - 24 Aug 2006 02:48 GMT
Just go for a simple ginkgo pill and save the rest of the trouble.  It
does not hurt to have your head blood circulation improved even if it
does not help your tinnitus but if you are lucky you may experience
some softening sound of tinnitus.

I am taking the ones made by Century 21 of Arizona.  Talk to a
pharmacist who has more experience with ginkgo than the alarmist
amateurs or the Nazi monopolist doctors in this ng...

FP
\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\
> I came across an ad for Equitab, a blend of "ginkgo extracts, dried rhizome
> of ginger, kelp, and cayenne."  Reportly, good for tinnitus and vertigo.
>
> I'm not rushing out to buy some, but any comments on this product?  Might be
> just another herbal blend.
drfrank21@gmail.com - 24 Aug 2006 03:32 GMT
> pharmacist who has more experience with ginkgo than the alarmist
> amateurs or the Nazi monopolist doctors in this ng...

You sure like that term "Nazi doctors"-  is very offensive and is a
sure sign of an idiot who has no clue in life. And who the hell
are you referring to anyway?????

frank
fyfpoon@gmail.com - 24 Aug 2006 05:52 GMT
> > pharmacist who has more experience with ginkgo than the alarmist
> > amateurs or the Nazi monopolist doctors in this ng...
>
> You sure like that term "Nazi doctors"-  is very offensive

It is offensive to someone who is a Nazi doctor but not to someone who
is not.  By claiming my statement is offensive, are you admitting you
are a Nazi doc?  You should have asked your interlocutor to define what
it means by a Nazi doc before running away with your blind anger.

Now listen to this: a Nazi doc, by my definition, is a doc produced by
an establishment or an association which intentionally retricts the
supply of doc into the market place in order to jack up the prices of
the services.

\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\

and is a
> sure sign of an idiot who has no clue in life. And who the hell
> are you referring to anyway?????
>
> frank
Martin Smith - 24 Aug 2006 07:26 GMT
> > > pharmacist who has more experience with ginkgo than the alarmist
> > > amateurs or the Nazi monopolist doctors in this ng...
[quoted text clipped - 3 lines]
> It is offensive to someone who is a Nazi doctor but not to someone who
> is not.  

It is offensive to me, and I'm not a doctor at all.

> By claiming my statement is offensive, are you admitting you
> are a Nazi doc?  You should have asked your interlocutor to define what
[quoted text clipped - 4 lines]
> supply of doc into the market place in order to jack up the prices of
> the services.

That means there are no "Nazi docs" then.

> \\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\
>
[quoted text clipped - 3 lines]
> >
> > frank
fyfpoon@gmail.com - 24 Aug 2006 07:54 GMT
> > > > pharmacist who has more experience with ginkgo than the alarmist
> > > > amateurs or the Nazi monopolist doctors in this ng...
[quoted text clipped - 5 lines]
>
> It is offensive to me, and I'm not a doctor at all.

Many things are offensive to you, and this should not have come as a
surprise.  You have been going after every post and saying something
for the sake of doing so.

> > By claiming my statement is offensive, are you admitting you
> > are a Nazi doc?  You should have asked your interlocutor to define what
[quoted text clipped - 6 lines]
>
> That means there are no "Nazi docs" then.

There are in *my* definition..............

> > \\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\
> >
[quoted text clipped - 3 lines]
> > >
> > > frank
Martin Smith - 24 Aug 2006 08:17 GMT
> > > > > pharmacist who has more experience with ginkgo than the alarmist
> > > > > amateurs or the Nazi monopolist doctors in this ng...
[quoted text clipped - 9 lines]
> surprise.  You have been going after every post and saying something
> for the sake of doing so.

I disagree with your view of doctors as nazis, and I have refuted it. I
also disagree with your implied view that doctors are supposed to have
the authority you attribute to them, and I have refuted that.

> > > By claiming my statement is offensive, are you admitting you
> > > are a Nazi doc?  You should have asked your interlocutor to define what
[quoted text clipped - 8 lines]
>
> There are in *my* definition..............

...which has been refuted.
fyfpoon@gmail.com - 24 Aug 2006 13:49 GMT
> > > > > > pharmacist who has more experience with ginkgo than the alarmist
> > > > > > amateurs or the Nazi monopolist doctors in this ng...
[quoted text clipped - 28 lines]
>
> ...which has been refuted.

In order to refute my definition, you have to first of all dispute the
claim that the medical authority in a certain country is a monopoly,
and secondly, even if it were, it should by your standards not be named
Nazi.

You have done none of both.
Martin Smith - 24 Aug 2006 14:40 GMT
> > > > > > > pharmacist who has more experience with ginkgo than the alarmist
> > > > > > > amateurs or the Nazi monopolist doctors in this ng...
[quoted text clipped - 34 lines]
> In order to refute my definition, you have to first of all dispute the
> claim that the medical authority in a certain country is a monopoly,

No, there is no necessary connection between monopoly and restriction of
numbers.

> and secondly, even if it were, it should by your standards not be named
> Nazi.

A Nazi is a member of the National Socialist Party, a fascist political
organization. I know of no medical authorities that come close to
fitting that description.

> You have done none of both.
Janice - 24 Aug 2006 22:51 GMT
Your definition only suits your argument and is not correct by the
common definition.

Chocolate was a specific candy originally and now has many meanings.
Time takes it's toll.

Let's all settle on "Nazi like"

>> > In article
>> > <1156402469.574133.279220@i3g2000cwc.googlegroups.com>,
[quoted text clipped - 70 lines]
>
>> You have done none of both.
Martin Smith - 24 Aug 2006 23:19 GMT
> Your definition only suits your argument and is not correct by the
> common definition.

The common definition still includes fascism. I don't know of any
medical authorities that are fascist.

> Chocolate was a specific candy originally and now has many meanings.
> Time takes it's toll.
>
> Let's all settle on "Nazi like"

The AMA, and medical schools in the US, Canada, and Europe are not
Nazi-like, so, no, let's don't settle on that.

> >> > In article
> >> > <1156402469.574133.279220@i3g2000cwc.googlegroups.com>,
[quoted text clipped - 70 lines]
> >
> >> You have done none of both.
Janice - 25 Aug 2006 04:05 GMT
This is only your opinion. Others have that opinions that many of
medical communities are "Nazi like".

I know of medical practicioners that have lost their right to practice
for practicing "unorthodox methods". The MDs involved lost due to
being bankrupt from legal fees and conceded. They practice
professionally no more. Now, you tell me that isn't "Nazi like" and I
will tell you, you are a liar with a hidden agenda.

>> Your definition only suits your argument and is not correct by the
>> common definition.
[quoted text clipped - 100 lines]
>> >
>> >> You have done none of both.
Martin Smith - 25 Aug 2006 12:21 GMT
> This is only your opinion. Others have that opinions that many of
> medical communities are "Nazi like".

I suppose so, but I have an argument, and they don't.

> I know of medical practicioners that have lost their right to practice
> for practicing "unorthodox methods". The MDs involved lost due to
> being bankrupt from legal fees and conceded. They practice
> professionally no more. Now, you tell me that isn't "Nazi like" and I
> will tell you, you are a liar with a hidden agenda.

That isn't Nazi-like.

> >> Your definition only suits your argument and is not correct by the
> >> common definition.
[quoted text clipped - 100 lines]
> >> >
> >> >> You have done none of both.
Janice - 28 Aug 2006 04:18 GMT
You show great denial in order to save face.

Please show consideration and trim your posting.

>> This is only your opinion. Others have that opinions that many of
>> medical communities are "Nazi like".
[quoted text clipped - 10 lines]
>
> That isn't Nazi-like.
Martin Smith - 28 Aug 2006 13:43 GMT
> You show great denial in order to save face.

Plagiarizing fortune cookies is just as bad as top posting.

Practicing unorthodox methods, as a member of a professional
organization with a code of conduct that requires certain testable
standards of treatment, is grounds for dismissal from that professional
organization. Just as designing bridges using unorthodox methods is
disallowed for certified engineers by their professional guilds, so too
is practicing unorthodox medical methods disallowed by certifying
medical guilds. And for the same reasons - they require scientific
validation, or specific permission based on accepted explanation. This
is not Nazi-like. It is standard procedure. It may mean professional
guilds are slow to embrace new knowledge, but that has nothing at all to
do with nazism.

> Please show consideration and trim your posting.

Please stop top posting.

> >> This is only your opinion. Others have that opinions that many of
> >> medical communities are "Nazi like".
[quoted text clipped - 10 lines]
> >
> > That isn't Nazi-like.
Janice - 29 Aug 2006 00:49 GMT
Many think it is just like you deny it is.

Your whining about posting style demonstrates your commitment to real
discussion.

> Practicing unorthodox methods, as a member of a professional
> organization with a code of conduct that requires certain testable
[quoted text clipped - 11 lines]
> all to
> do with nazism.
Martin Smith - 29 Aug 2006 04:29 GMT
> Many think it is just like you deny it is.

No, they don't.

> Your whining about posting style demonstrates your commitment to real
> discussion.

This isn't a real discussion.

> > Practicing unorthodox methods, as a member of a professional
> > organization with a code of conduct that requires certain testable
[quoted text clipped - 11 lines]
> > all to
> > do with nazism.
Martin Smith - 25 Aug 2006 12:21 GMT
> This is only your opinion. Others have that opinions that many of
> medical communities are "Nazi like".
[quoted text clipped - 4 lines]
> professionally no more. Now, you tell me that isn't "Nazi like" and I
> will tell you, you are a liar with a hidden agenda.

By the way, top posting is rude and selfish.

> >> Your definition only suits your argument and is not correct by the
> >> common definition.
[quoted text clipped - 100 lines]
> >> >
> >> >> You have done none of both.
Janice - 28 Aug 2006 04:17 GMT
Picking at the correct way of posting is just cry-baby like.

>> This is only your opinion. Others have that opinions that many of
>> medical communities are "Nazi like".
[quoted text clipped - 128 lines]
>> >> >
>> >> >> You have done none of both.
Martin Smith - 28 Aug 2006 13:44 GMT
> Picking at the correct way of posting is just cry-baby like.

So is picking at posting length.

> >> This is only your opinion. Others have that opinions that many of
> >> medical communities are "Nazi like".
[quoted text clipped - 128 lines]
> >> >> >
> >> >> >> You have done none of both.
drfrank21@gmail.com - 24 Aug 2006 14:55 GMT
>> It is offensive to someone who is a Nazi doctor but not to someone who
> is not.  By claiming my statement is offensive, are you admitting you
> are a Nazi doc?  You should have asked your interlocutor to define what
> it means by a Nazi doc before running away with your blind anger.

Tell me that you're repulsed by a pedophile?? If you said yes, by your
logic, you would be one. Foot in mouth disease.

> Now listen to this: a Nazi doc, by my definition, is a doc produced by
> an establishment or an association which intentionally retricts the
> supply of doc into the market place in order to jack up the prices of
> the services.

You really are a grade-A moron. Don't you realize whenever
you post something you make an a.s out of yourself??
Your definition of a nazi doc is just whacked and you didn't
answer who on the ng (you made it plural) are the "nazi
docs". You are clueless about nazi germany and what
the nazi docs actually did.

frank
Susan - 24 Aug 2006 15:03 GMT
> You really are a grade-A moron. Don't you realize whenever
> you post something you make an a.s out of yourself??
> Your definition of a nazi doc is just whacked and you didn't
> answer who on the ng (you made it plural) are the "nazi
> docs". You are clueless about nazi germany and what
> the nazi docs actually did.

Frank, not for nuthin but he's smart enough to keep you engaged, even
after years.

Most of us only see his posts when you respond to him.

Susan
drfrank21@gmail.com - 24 Aug 2006 19:14 GMT
> x-no-archive: yes
>
[quoted text clipped - 11 lines]
>
> Susan

I've seen gerbils with more intelligence than what Francis
displays so don't give him too much credit. I do read his
posts just to see how much more over the top he can
get. I guess it's like slowing down to see a car
wreck (I have though, more than once, stopped to give
aid to the accident victims) .

But there are just times where he should not get
free rein and should be called out; I do try to keep
it to a minimum. I'm going to trust people like
yourself and other sane people here to keep me
in check from engaging in  any brain numbing
conversations with this genius.

Thanks.
frank

frank
Jim Chinnis - 24 Aug 2006 19:37 GMT
drfrank21@gmail.com wrote in part:

> I'm going to trust people like
>yourself and other sane people here to keep me
>in check from engaging in  any brain numbing
>conversations with this genius.

FWIW, I agree with Susan. The best response is none at all. Ideally, you
don't read the posts of such people.

After all, they post because of their audience. Deprive them of it.
Signature

Jim Chinnis / Warrenton, Virginia, USA
Want to discuss Meniere's? See http://groups.yahoo.com/group/MenieresDG

Susan - 24 Aug 2006 19:50 GMT
> I've seen gerbils with more intelligence than what Francis
> displays so don't give him too much credit. I do read his
> posts just to see how much more over the top he can
> get. I guess it's like slowing down to see a car
> wreck (I have though, more than once, stopped to give
> aid to the accident victims) .

Do you stop to view the scene of a wreck and stay there, without leaving?

> But there are just times where he should not get
> free rein and should be called out; I do try to keep
> it to a minimum. I'm going to trust people like
> yourself and other sane people here to keep me
> in check from engaging in  any brain numbing
> conversations with this genius.

Count on it.  ;-)

Susan
drfrank21@gmail.com - 24 Aug 2006 20:36 GMT
> x-no-archive: yes
>
[quoted text clipped - 3 lines]
>
> Do you stop to view the scene of a wreck and stay there, without leaving?

Like I stated, I've helped out more tha