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Medical Forum / Diseases and Disorders / Tinnitus / June 2006

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Bob - 21 Jun 2006 21:28 GMT
Inner ear cells may be able to regenerate
LOS ANGELES, June 21 (UPI) -- U.S. researchers say they've determined
the specialized hair cells in the inner ear that enable people to hear
might be able to regenerate.

The findings of a mouse study at the House Ear Institute in Los Angeles
might have therapeutic implications for certain types of deafness.

Researchers Neil Segil, Andrew Groves and colleagues have shown
supportive cells from the postnatal mouse inner ear retain the ability
to divide and turn into new sensory hair cells in culture.

It's known that some vertebrates, such as birds, are able to perform
that feat in vivo, but the regenerative capacity of mammalian hair
cells has, so far, been uncertain.

The scientists say their study's results strongly suggest the mammalian
cochlea retains the capacity for regeneration but the signals for
regeneration are either absent or actively inhibited in vivo.

The research appears in the journal Nature.

Bob
drfrank21@gmail.com - 22 Jun 2006 02:54 GMT
> Inner ear cells may be able to regenerate
> LOS ANGELES, June 21 (UPI) -- U.S. researchers say they've determined
[quoted text clipped - 19 lines]
>
> Bob

Interesting but should be taken with a grain of salt. In vitro can
be very different than in vivo. I just wonder if stem cell research
may, in the end, pave the way for treating deafness.

frank
Eva Quesnell - 22 Jun 2006 15:40 GMT
> Interesting but should be taken with a grain of salt. In vitro can
> be very different than in vivo. I just wonder if stem cell research
> may, in the end, pave the way for treating deafness.
>
> frank

The Good Lord willin' and the creek don't rise.  They are making some
fantastic strides with stem cells now.  It could prove a great boon to us
all.

Eva
jga.socal - 24 Jun 2006 06:13 GMT
> > Inner ear cells may be able to regenerate
> > LOS ANGELES, June 21 (UPI) -- U.S. researchers say they've determined
[quoted text clipped - 25 lines]
>
> frank

btw: whats the big controversy with cord stem cells?  I know there is a
way to harvest peripheral blood stem cells from healthy adults by
prepping the donor with filgrastim.  Are cord stem cells better suited
for research?
Jim
Mr. Y - 27 Jun 2006 02:51 GMT
I actually banked stem cells from my youngest daughter's cord blood.  Maybe
it will pay off.   With all this debate over stem cells, I don't understand
why they can't use more cord blood.  They can actually take it from the
placenta side of the ambilical cord after delivery.

>> > Inner ear cells may be able to regenerate
>> > LOS ANGELES, June 21 (UPI) -- U.S. researchers say they've determined
[quoted text clipped - 31 lines]
> for research?
> Jim
 
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