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Medical Forum / Diseases and Disorders / Tinnitus / May 2006

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Kombucha Tea on PUBMED

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jga.socal - 18 May 2006 05:35 GMT
PUBMED has 16 readable studies on Kombucha at this point in time. Last
study was September 2004. I've summarized what I found. Short quote is
provided to back my interpretation.  PUBMED is a database maintained by
the US National Instutute of Health.

NEGATIVE CONCLUSIONS: 4
POSITIVE CONCLUSIONS: 2
POSTIVES FOR RODENTS ONLY: 3
INFORMATIONAL: 4
NO CONCLUSION: 3
UNREADABLE: 4

Reference:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=search&term=Kombucha

NEGATIVE
1    Derk CT, Sandorfi N, Curtis MT.
A case of anti-Jo1 myositis with pleural effusions and pericardial
tamponade developing after exposure to a fermented Kombucha beverage.
"Kombucha 'mushroom', a symbiosis of yeast and bacteria, is postulated
to be the trigger for our patient's disease owing to the proximity of
his symptoms to the consumption of the Kombucha beverage."

INFORMATIONAL: IDENTIFIES Yeast cultures
2 Int J Food Microbiol. 2004 Sep 1;95(2):119-26.

POSITIVE
3 Biomed Environ Sci. 2003 Sep;16(3):276-82.
Lead induced oxidative stress: beneficial effects of Kombucha tea.
"CONCLUSION: The results suggest that K-tea has potent antioxidant and
immunomodulating properties."

NO CONCLUSIONS
4  Syst Appl Microbiol. 1998 Mar;21(2):220-9.
Acetobacter intermedius, sp. nov.

NEGATIVE
5 Forsch Komplementarmed Klass Naturheilkd. 2003 Apr;10(2):85-7.
Kombucha: a systematic review of the clinical evidence.
"the largely undetermined benefits do not outweigh the documented risks
of kombucha. It can therefore not be recommended for therapeutic use."

INFORMATIONAL
6 FEMS Yeast Res. 2001 Jul;1(2):133-8.     Related Articles, Links
Zygosaccharomyces kombuchaensis, a new ascosporogenous yeast from
'Kombucha tea'.

POSITIVE
7 Biomed Environ Sci. 2001 Sep;14(3):207-13.
Studies on toxicity, anti-stress and hepato-protective properties of
Kombucha tea.
"K-tea has anti-stress and hepato-protective activities."

POSITIVE FOR RATS
8 Biomed Environ Sci. 2000 Dec;13(4):293-9.
Subacute (90 days) oral toxicity studies of Kombucha tea.
"rats fed KT for 90 days showed no toxic effects."

FERMENTATION TIME INFO. NO CONCLUSIONS
9 J Appl Microbiol. 2000 Nov;89(5):834-9.
Changes in major components of tea fungus metabolites during prolonged
fermentation.
"the desired quality or composition of kombucha can be obtained through
the proper control of fermentation time."

POSITIVE FOR MICE.  UNKNOWN FOR PEOPLE
10 Nutrition. 2000 Sep;16(9):755-61.
Effects of chronic kombucha ingestion on open-field behaviors,
longevity, appetitive behaviors, and organs in c57-bl/6 mice: a pilot
study.
"This pilot study reports longevity, general health, and open-field
exploratory behavioral outcomes... Comparable effects and mechanisms in
humans remain uncertain, as do health safety issues, because serious
health problems and fatalities have been reported and attributed to
drinking kombucha"

NO STUDY CITED
11 J Food Prot. 2000 Jul;63(7):976-81.
Kombucha, the fermented tea: microbiology, composition, and claimed
health effects.
"Kombucha consumption has proven to be harmful in several documented
instances."

POSITIVE IN RATS
12  J Ethnopharmacol. 2000 Jul;71(1-2):235-40.
Effect of Kombucha tea on chromate(VI)-induced oxidative stress in
albino rats.
"Kombucha tea has potent anti-oxidant and immunopotentiating
activities."

PROPERTIES STUDY
13 J Agric Food Chem. 2000 Jun;48(6):2589-94.
Kombucha fermentation and its antimicrobial activity.
"Kombucha proved to exert antimicrobial activities against E. coli, Sh.
sonnei, Sal. typhimurium, Sal. enteritidis, and Cm. jejuni ... suggests
the presence of antimicrobial compounds other than acetic acid and
large proteins in Kombucha."

14 Laier B.  (in Danish. No abstract)

15 Ishida Y  (no abstract)

NO CONCLUSION about K
16  Med J Aust. 1998 Dec 7-21;169(11-12):644-6.
Lead poisoning from drinking Kombucha tea brewed in a ceramic pot.
"symptomatic lead poisoning requiring chelation therapy in a married
couple who had been drinking Kombucha tea for six months, brewing the
tea in a ceramic pot."

UNKNOWN CONCLUSION
17  JAMA. 1998 Nov 11;280(18):1567-8.     Related Articles, Links
Cutaneous anthrax associated with the Kombucha "mushroom" in Iran.
No Abstract

NEGATIVE
18 J Gen Intern Med. 1997 Oct;12(10):643-4.
Probable gastrointestinal toxicity of Kombucha tea: is this beverage
healthy or harmful?
"use of Kombucha tea in proximity to onset of symptoms and symptom
resolution on cessation of tea drinking suggest a probable etiologic
association."

NEGATIVE
20 MMWR Morb Mortal Wkly Rep. 1995 Dec 8;44(48):892-3, 899-900.
Unexplained severe illness possibly associated with consumption of
Kombucha tea--Iowa, 1995.
"persons refrain from drinking Kombucha tea until the role of the tea
in the two cases of illness had been evaluated fully"
fyfpoon@gmail.com - 18 May 2006 10:28 GMT
Do you have a picture of what it looks like?
jga.socal - 18 May 2006 16:43 GMT
Do a google image search for 'kombucha tea'.  Plenty of pictures there.
Apparently it's packaged very nicely for sale by seveal outfits. The
pubmed literature leaves me skeptical.  This is another case where it
would be nice to see feedback & testimonials from a large number of
people who drink this tea.
Eva Quesnell - 18 May 2006 21:14 GMT
> Do a google image search for 'kombucha tea'.  Plenty of pictures there.
> Apparently it's packaged very nicely for sale by seveal outfits. The
> pubmed literature leaves me skeptical.  This is another case where it
> would be nice to see feedback & testimonials from a large number of
> people who drink this tea.

Yes, it is easy to mess up when you brew the stuff, too.  You cannot let
metal touch any of the ingredients.  You have to boil the water in a glass
pot, use a wooden spoon to stir.  You even have to be sure the tea bags
don't have those little staples on them.  If you let it ferment without a
good covering on it, you can be growing dangerous microorganisms along
with your tea.  Back when I did this, it was THE THING!  Everybody was
doing it, and then they started coming out with all kinds of warnings.  I
told you it was an outrageous thing I'd tried.  Don't know if I'd ever do
it again either.  It would be nice to have a good study on it, tho.
fyfpoon@gmail.com - 19 May 2006 02:46 GMT
I cannt find the Chinese name for it.  It sounds like 'gold treasure
tea' to me from the sound of it.
Murray Grossan - 19 May 2006 05:54 GMT
On 5/18/06 8:43 AM, in article
1147967016.952290.93220@38g2000cwa.googlegroups.com, "jga.socal"
<jganders@gmail.com> wrote:

> Do a google image search for 'kombucha tea'.  Plenty of pictures there.
>  Apparently it's packaged very nicely for sale by seveal outfits. The
> pubmed literature leaves me skeptical.  This is another case where it
> would be nice to see feedback & testimonials from a large number of
> people who drink this tea.

Yes, especially pictures of happy smiling handsome faces that accompany well
written testimonials in perfect english and spelling.  
fyfpoon@gmail.com - 19 May 2006 14:23 GMT
Those modern doctors who injected all sorts of dangerous solution into
my body were also well groomed and smiling, and so did those who
prescribed all sorts of useless med to me for megabugs.  Appearance is
very deceitful!
Martin Smith - 19 May 2006 18:00 GMT
> Those modern doctors who injected all sorts of dangerous solution into
> my body were also well groomed and smiling, and so did those who
> prescribed all sorts of useless med to me for megabugs.  Appearance is
> very deceitful!

You mean deceiving. There certainly are bad doctors. You seem to have
run into more than your share. Is this typical of Chinese medicine?
fyfpoon@gmail.com - 20 May 2006 07:48 GMT
During the onset of my T, I visited about 15 'modern' doctors or
doctors who practice western medicine here in China and Hong Kong. Some
are ENT, some neurologists, and the rest general physicians.  Most of
their advices were either useless or even harmful! Out of all their
treatments and advices, the only things useful were (1)betahistine,
(2)gingko biloba, and (3)hot spring bath. Each one comes from a
different doctor.

I also went to visit 2 Chinese herbalists.  None of them prescribed me
gingko biloba.  I did not have enough patience to go through their herb
treatment as my T was like a tormenting hell and i was looking for a
quick fix.

Finally, I accidentally ran into an acupuncturist in Vancouver of
Canada.  After 2 treatments, all that 'somatic' discomfort in my head I
had been complaining in this ng
was gone!  I think i was suffering from a nerve illness that existed
side by side with my T.  Once the head discomfort was gone, the T right
away became much softer but was still there.  It has been improving
ever since....I should have gone for an acupuncture treatment when I
was in China at that time but the stupid 'controlled' studies cited
around in this ng sort of discouraged me from trying it out.

I am going to have hot spring vacation again...
Martin Smith - 20 May 2006 08:36 GMT
>During the onset of my T, I visited about 15 'modern' doctors or
>doctors who practice western medicine here in China and Hong Kong. Some
[quoted text clipped - 3 lines]
>(2)gingko biloba, and (3)hot spring bath. Each one comes from a
>different doctor.

Why did you visit 15 doctors for tinnitus?

>I also went to visit 2 Chinese herbalists.  None of them prescribed me
>gingko biloba.  I did not have enough patience to go through their herb
[quoted text clipped - 12 lines]
>
>I am going to have hot spring vacation again...
fyfpoon@gmail.com - 20 May 2006 11:28 GMT
It was because none of them was able to release me from my tormenting
illness or 'torturing chamber'.  Finally I took the initiativeness to
take hydrochloridethiazer out of my high blood pressure regimen and the
sky was finally clear!  I had suspected it was raising hell for me but
when I asked around no doctor was in agreement or at a loss to know.
One day, when I was in my ENT office, I saw a pamphlet hanging on the
wall warning people about the kinds of medication that affect ear
hearing.  One of the medicines listed as possibly causing hearing
disability is direutics.  That was why I did it.  So the old camp of
trouble was gone but another camp of trouble came after HCTZ had been
taken out.  I felt pressure on my left head side.  And it felt like a
cluster of somatic discomfort that moved from side to side in my hear.
When it was on my right side, it was bearable, but then it went to my
left side, it was very difficult to bear. The doctors in this ng and my
doctor in HK suspected it was excessive inner fluid.  And a doctor here
commented it was seizure while another disagreed.  None of the doctors
I visited knew what it was.  A neurologist commented it was a blood
vein being blocked so he prescribed me with intravenous injection of
very dangerous blood thinning solution.  It was useful for a few days
and after a few days the trouble came back again.  Life was a living
hell to me!  Then finally I talked to a doctor about my case and he
prescribed me another kind of diuretics.  This time the new kind was
OK.  It softened the T sound and alleviated the 'somatic' discomfort
but the latter was still there and was still moving from side to side
in my head.  I thought that was what life was going to be from that
moment onward until my daughter in Vancouver mentioned an acupuncturist
whom her classmates call 'magic doctor'.  This lady acupuncturist
graduated from the Imperial College of Chinese Medicine in Peking.
After two treatments, one on left and ther other one on the right, the
discomfort was 90% gone!  Now is is 99% gone!  I asked her what the
problem was.  She said that it was due to a pinched nerve in the spine,
and she ran into cases similar to that in Peking from people who sit in
front of the computer for prolonged time period with improper head
posture.  There it goes..Now, I am no longer using pillow but only a
large towel wrapped to support my neck.

'You see, if i had not been under the influence of all that controlled
studies cited around in this ng, i would have gone for acupuncture
treatment while i was in China and would have had my problem taken care
of much more early.
Martin Smith - 20 May 2006 12:01 GMT
>It was because none of them was able to release me from my tormenting
>illness or 'torturing chamber'.

But didn't any of those 15 doctors tell you there is no specific
medicinal cure for tinnitus? 15 doctors in a row were that bad?

I'm in Norway. I went to my general MD, when I got tinnitus. He and I
agreed to rule out infection, so I took some antibiotics and some
medicine to reduce swelling and inflamation. No change. He sent me to
an ENT. He examined my ears and found nothing wrong. He tested my
hearing and said I didn't have the hearing pattern of a person with
tinnitus, but (and here is the important point), he said tinnitus is
not that well understood and there is no specific cure. He said there
are lots of things to try, and he suggested some of them, but he
didn't prescribe anything.

So that was it. Why would I go to 14 more doctors to be told the same
thing? Why didn't any of the doctors you saw tell you that?

> Finally I took the initiativeness to
>take hydrochloridethiazer out of my high blood pressure regimen and the
[quoted text clipped - 7 lines]
>taken out.  I felt pressure on my left head side.  And it felt like a
>cluster of somatic discomfort that moved from side to side in my hear.

Wait a minute. Are you saying your heart doctor didn't tell you about
the problems that could be caused by the medications he prescribed?
That has never happened to me either, but I always ask about side
effects when I am prescribed new medication?

>When it was on my right side, it was bearable, but then it went to my
>left side, it was very difficult to bear. The doctors in this ng and my
[quoted text clipped - 19 lines]
>posture.  There it goes..Now, I am no longer using pillow but only a
>large towel wrapped to support my neck.

The first place I looked, after the ENT told me I was pretty much on
my own, was this ng. I immediately found the advice about neck
problems being a sometime cause of tinnitus. So I went back to my MD
and asked him to prescribe an MRI to determine whether I had neck
damage. The MRI showed neck damage, so I went to a physio therapist to
get help with that. I can't say for sure whether it lowered the T, but
it did lower the neck pain.

So I started swimming again. I used to swim a lot. Swimming makes my T
disappear and swimming exercises the neck muscles a lot and it relaxes
the neck and back muscles.

>'You see, if i had not been under the influence of all that controlled
>studies cited around in this ng, i would have gone for acupuncture
>treatment while i was in China and would have had my problem taken care
>of much more early.

You were under your own control all along, and you are trying to blame
all the doctors you demanded a cure from. Nobody goes to 15 doctors
unless they believe doctors can fix everything.
fyfpoon@gmail.com - 20 May 2006 13:07 GMT
(1)No, none of these doctor told me there is no specific cure for
tinnitus.  A psychologist in a mental hospital did once tell me that
when a T gets old, it is incurable in terms of its staying there for a
long long time.  But other doctors disagreed.  I actually talked to one
patient whose T was totally cured!  So why should I believe things the
way you believe?  How you choose to believe things is a function of
your environment and experiences which differ from mine hugely.

(2)None of the doctors I went to told me about the relationship between
drug interaction and tinnitus.  These are not just the doctors
practicing western medicine in China, but some are the glamorous ones
in the Adventist Hospital in Hong Kong.

(3)I also came to this ng and discovered the concept of somatic
tinnitus.  That was why I went to check out with a chiro.  It relaxed
my spine but the discomfort in my head was still there.

(4)Then Martin exploded:"You were under your own control all along, and
you are trying to blame all the doctors you demanded a cure from.
Nobody goes to 15 doctors unless they believe doctors can fix
everything."

Martin, how do you know that?  Who are you to lecture me?  Have you
done a survey of patients 'all over the world' to have come to the
conclusion that "Nobody goes to 15 doctors unless they believe doctors
can fix everything."  You don't set up your own rules and use them to
measure against other people's ways of doing things. The world we live
in is very large and you are generalizing for the whole world in such a
way that is reminiscient of those principle-oriented/small-minded
British in Hong Kong.  The latter are not even very intellectual
people.

Bye...
Martin Smith - 20 May 2006 17:31 GMT
> (1)No, none of these doctor told me there is no specific cure for
> tinnitus.  A psychologist in a mental hospital did once tell me that
[quoted text clipped - 3 lines]
> way you believe?  How you choose to believe things is a function of
> your environment and experiences which differ from mine hugely.

But you went to 15 doctors, and they all told you something different.
If it had been me, after being told 6 or 7 different stories by
different doctors, I'm sure I would have realized there was no point in
going to more doctors.

> (2)None of the doctors I went to told me about the relationship between
> drug interaction and tinnitus.  These are not just the doctors
> practicing western medicine in China, but some are the glamorous ones
> in the Adventist Hospital in Hong Kong.

Did you ask them?

> (3)I also came to this ng and discovered the concept of somatic
> tinnitus.  That was why I went to check out with a chiro.  It relaxed
[quoted text clipped - 6 lines]
>
> Martin, how do you know that?  

You went to 15 different doctors and got 15 different stories. Nobody
made you go to the 15th doctor after getting 14 different stories from
14 different doctors. You chose to do it.

> Who are you to lecture me?  Have you
> done a survey of patients 'all over the world' to have come to the
[quoted text clipped - 7 lines]
>
> Bye...
jga.socal - 19 May 2006 17:08 GMT
>>Yes, especially pictures of happy smiling handsome faces that accompany well
written testimonials in perfect english and spelling.

Assuming your comment is serious...

I dont know why you are so cynical of testimonials from real people.
Perhaps your training has taught you to disregard what the patient
says?  Shall doctors put muzzles on their patients and just read the
numbers from the tests to arrive at the diagnoses?  Perhaps you should
become familiar with some of the social sciences too. For instance,
there are techniques poll and survey professionals employ to screen out
biased responses.  In small surveys bias can be a problem.  When the
response set becomes large the bias effect becomes negligible.

Where should I be more concerned about bias?
A) Survey results from people with afflictions who have tried
alternatives and who generally have no reason to mislead?
B) Recommendations by medical professionals who are often financially
engaged with drug companies offering FDA approved solutions?

Hint: Its fairly easy to spot disingenuousness when reading through
survey responses.

A more direct resolution to your concerns may be to simply disqualify
survey responses from anyone who cracks a smile (picture required)
and/or where the response has no english grammatical, spelling, or
syntax errors. IE: Exclude happy, educated people.
:-)
drfrank21@gmail.com - 19 May 2006 21:33 GMT
> >>Yes, especially pictures of happy smiling handsome faces that accompany well
> written testimonials in perfect english and spelling.
[quoted text clipped - 24 lines]
> syntax errors. IE: Exclude happy, educated people.
> :-)

The problem with many companies touting "testimonials" is that
it is unknown just how honest and accurate these testimonials
really are. Most times it is impossible to check the veracity
of these testimonials so these can range from being outright
ficticious to just being paid endorsements. So one has no idea
if these are actually "real" people or just plants.And even if the
testimonials were legitimate, one doesn't know if those that
are listed were outweighed by the hundreds or thousands
of customers who were disatisfied (obviously the company would
keep this hidden).

These companies  usually do not hire independent researchers to
scientifically poll those who have tried or used whatever product.

There was a magazine publication that recently showed the picture
of the very same woman (but different names) in three different
ads (one in a diet pill breakthrough, another for a sleep aid and I
forget the third ad). So it looks like the companies used a stock
photo and just changed the first name and voila, instant
testimonials.

A few yrs back I was getting estimates for a new fence and this one
company was very impressive with two full pages of references and
testimonials.I was curious and checked 6-7 "testimonials" around
my side of town. Every single one showed a made-up address
and the one that had a valid address had NO fence at all. Needless
to say, I didn't use that company but if one didn't actually check
like I did one would have assumed that this was one great fencing
contractor.

I'd bet you anything that if you tried to get actual names and phone
numbers of testimonials from say, any alternative health medication,
whether diet aids or tinnitus herbs, from these ads you get nowhere.

frank
jga.socal - 20 May 2006 18:46 GMT
drfrank wrote:
"The problem with many companies touting "testimonials" is that it is
unknown just how honest and accurate these testimonials really are."

Totally agree. I'm referring to unbiased testimonials, not company
sponsored.
drfrank21@gmail.com - 21 May 2006 00:53 GMT
> drfrank wrote:
> "The problem with many companies touting "testimonials" is that it is
> unknown just how honest and accurate these testimonials really are."
>
> Totally agree. I'm referring to unbiased testimonials, not company
> sponsored.

And part of the problem is that it can difficult to tell the
difference between the "unbiased" testimonials and those
that are not legitimate and that's why the scientific
studies may be more worthwhile.

frank
jga.socal - 20 May 2006 19:45 GMT
A word about this topic.
I posted the Kombucha topic because Kombucha tea, aka K-Tea has come up
in this ng several times over the years as a treatment for T.  I
thought I'd help out by posting a summary of studies done on K-Tea as
published in PubMed. Whether PubMed is a good source of sientific
studies may be another topic but I know it is a widely used resource
for medical professionals in this country. The purpose of the K-Tea
post was just a FYI. Reading thru PubMed technical abstracts is not a
fun thing to do. Hopefully a summary of the abstracts was helpful to
those considering the value of taking K-Tea for their T.
Jim
jga.socal - 20 May 2006 19:59 GMT
Oh crap!  The link I provided may not work for you.
1. Go to NCBI: http://www.ncbi.nlm.nih.gov/
2. Near top: Search 'All Databases' for 'Kombucha'. Click [Go]
3. Resulting page, top left, should say 26 results for PubMed.  Click
it.
4. If the resulting page says 'No items found', uncheck the [X] Limits
box and search again.
Thanx

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