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Medical Forum / Diseases and Disorders / Tinnitus / October 2004

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TINNITUS TRIAL

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Silverette - 20 Oct 2004 13:03 GMT
I am persuing Cord Blood Stem Cell treatment for Tinnitus.
> If you are interested in becoming part of this study group, or simply
> monitoring my progress please contact me at +27 83 764 6629 or email me
> at anthony@creativelab.co.za ( please use "Tinnitus Trial" as your
subject )*TERMS&CONDITIONS*
ENTconsult - 20 Oct 2004 16:32 GMT
Is the writer serious or is this a joke?

would you like a short or a long list of diseases that are transmitted by human
blood?
Murray Grossan, M.D.
http://www.ent-consult.com
Elly Byrne - 20 Oct 2004 21:34 GMT
http://www.creativelab.co.za/
is a very attractive picture.
But I hate these fancy splash pages.
Then it has a peekaboo menu where you just have to guess what the
various icons mean.
It is a webdesign place. I wouldn't use him.

Where he comes into stem cell research I have no idea.

Tinnitus is a pain in the neck
Elly's Tinnitus Resources
http://eebee.net/

>Is the writer serious or is this a joke?
>
>would you like a short or a long list of diseases that are transmitted by human
>blood?
>Murray Grossan, M.D.
>http://www.ent-consult.com
Silverette - 21 Oct 2004 11:13 GMT
Thanx for my warm welcome!

Thank you for your input but I would not talk about webdesign if I were
you :) Creativelab may be a bit misleading regarding stem cell research,
Creativelab is my freelance website and has got nothing to do with a
medical lab or the company I'm dealing with, sorry my apologies.
I have cochlea damage from playing drums for 7 years, and yes I believe
that stem cell treatment might do the trick or not. Like anything its
trial and error.

Regarding the ENT reply, No its not a joke. I would like to know what your
thinking is behind stem cell treatment? because ENT's and me well.... maybe
just the ENT's in South Africa. We do not have support of any kind in SA so
its pretty much a case of do it yourself. When you ask them Questions they
say they can't really help. So please restore my faith in ENT.

The company that treats people is an USA/UK based company that has been
treating patients all over the world including South Africa for the last 2
years with positive results and no side effects. The first stem cell bank
in Africa is also opening in Cape Town soon.
drfrank21 - 21 Oct 2004 17:17 GMT
> Thanx for my warm welcome!
>
[quoted text clipped - 8 lines]
> years with positive results and no side effects. The first stem cell bank
> in Africa is also opening in Cape Town soon.

I'm also confused about your post- cord blood/stem cells are used
primarily
in treating cancer (leukemia's) and I know of no application of this
for tinnitus.

Below was taken from a website- I see no tinnitus treatment (to me it
wouldnt make any sense that stem cells could be a treatment for
tinnitus
unless it was too somehow "regrow" hair cells- even then it would be a
reach).

frank

Diseases Treated with Stem Cells

Acute Leukemias
Acute Biphenotypic Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Undifferentiated Leukemia

Chronic Leukemias
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)

Myelodysplastic Syndromes
Amyloidosis
Chronic Myelomonocytic Leukemia (CMML)
Refractory Anemia (RA)
Refractory Anemia with Excess Blasts (RAEB)
Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
Refractory Anemia with Ringed Sideroblasts (RARS)

Stem Cell Disorders
Aplastic Anemia (Severe)
Congenital Cytopenia
Dyskeratosis Congenita
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)

Myeloproliferative Disorders
Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Essential Thrombocythemia
Polycythemia Vera

Lymphoproliferative Disorders
Hodgkin's Disease
Non-Hodgkin's Lymphoma
Prolymphocytic Leukemia

Phagocyte Disorders
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis

Liposomal Storage Diseases
Adrenoleukodystrophy
Gaucher's Disease
Hunter's Syndrome (MPS-II)
Hurler's Syndrome (MPS-IH)
Krabbe Disease
Maroteaux-Lamy Syndrome (MPS-VI)
Metachromatic Leukodystrophy
Morquio Syndrome (MPS-IV)
Mucolipidosis II (I-cell Disease)
Mucopolysaccharidoses (MPS)
Niemann-Pick Disease
Sanfilippo Syndrome (MPS-III)
Scheie Syndrome (MPS-IS)
Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
Wolman Disease

Histiocytic Disorders
Familial Erythrophagocytic Lymphohistiocytosis
Hemophagocytosis
Histiocytosis-X
Langerhans' Cell Histiocytosis

Inherited Erythrocyte Abnormalities
Beta Thalassemia Major
Blackfan-Diamond Anemia
Pure Red Cell Aplasia
Sickle Cell Disease

Congenital (Inherited) Immune System Disorders
Absence of T & B Cells SCID
Absence of T Cells, Normal B Cell SCID
Ataxia-Telangiectasia
Bare Lymphocyte Syndrome
Common Variable Immunodeficiency
DiGeorge Syndrome
Kostmann Syndrome
Leukocyte Adhesion Deficiency
Omenn's Syndrome
Severe Combined Immunodeficiency (SCID)
SCID with Adenosine Deaminase Deficiency
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

Other Inherited Disorders
Cartilage-Hair Hypoplasia
Ceroid Lipofuscinosis
Congenital Erythropoietic Porphyria
Glanzmann Thrombasthenia
Lesch-Nyhan Syndrome
Osteopetrosis
Tay Sachs Disease

Inherited Platelet Abnormalities
Amegakaryocytosis / Congenital Thrombocytopenia

Plasma Cell Disorders
Multiple Myeloma
Plasma Cell Leukemia
Waldenstrom's Macroglobulinemia

Other Malignancies
Brain Tumors
Ewing Sarcoma
Neuroblastoma
Ovarian Cancer
Renal Cell Carcinoma
Small-Cell Lung Cancer
Testicular Cancer

Autoimmune Diseases
Evan Syndrome
Multiple Sclerosis (Experimental)
Rheumatoid Arthritis (Experimental)
Systemic Lupus Erythematosus (Experimental)

Emerging Clinical Stem Cell Applications

Alzheimer's Disease

Parkinson's Disease

Stroke
Doctors are focusing on the ability of the stem cell to differentiate
into nerve cells. The approach to treatment would be to regenerate new
and healthy nerve cells (tissue) to reduce, alleviate, or eliminate
the symptoms or effects of diseases like Alzheimer's and Parkinson's
and repair damage caused by stroke.

Sanchez-Ramos, J., Song, S., Kamath, S., et al. Expression of neural
markers in human umbilical cord blood. Experimental Neurology.
2001;171:109-115.
Chen, J., Sanberg, P., Li, Y., et al. Intravenous administration of
human umbilical cord blood reduces behavioral deficits after stroke in
rats. Stroke. 2001;32:2682-2688.

Diabetes
Success using stem cells to regenerate pancreas function and insulin
production. May help insulin dependent patients become free of
adjunctive therapy (such as insulin injections).

Domenick, M., Ildstad, S. Impact of bone marrow transplantation on
type I diabetes. World Journal of Surgery. 2001;25:474-480.
Heart Disease
Success regenerating heart tissue and blood vessels for treatment of
heart disease or traumatic injury to the heart.

Assmus, B., Schachinger, V., Teupe, C., et al. Transplantation of
progenitor cells and regeneration enhancement in acute myocardial
infarction (TOPCARE-AMI). Circulation. 2002;106:3009-3017.
Liver Disease
Stem cells differentiated into liver cells in mice. Future
applications may include repairing liver damage caused by cirrhosis,
viral infection, trauma, chemotherapy, or radiation therapy.

Wang X., Ge S., McNamara G., et al. Albumin-expressing hepatocyte-like
cells develop in the livers of immune-deficient mice that received
transplants of highly purified human hematopoietic stem cells. Blood.
2003;101(10):4201-4208.
Lupus
Following stem cell transplantation patients with severe lupus have
been able to regenerate blood cells that are completely free of the
disease.

Brunner, M., Greinix, H., Redlich, K., et al. Autologous blood stem
cell transplantation in refractory systemic lupus erythematosus with
severe pulmonary impairment. Arthritis & Rheumatism.
2002;46(6):1580-1584.
Multiple Sclerosis
Stem cell transplantation has stopped and even reversed disease
progression for some patients with multiple sclerosis.

Kozak, T. Hematopoietic stem cell transplantation in the treatment of
autoimmune diseases. The Middle European Journal of Medicine.
2002;114(1-2; 7-13)
Muscular Dystrophy
Stem cells have been proven to fuse into skeletal muscle cells in
patients with muscular dystrophy. Transplantation may help slow or
stop the progression of muscle wasting.

Gussoni, E., Bennett, R., Muskiewicz, K., et al. Long term persistence
of donor nuclei in a duchenne muscular dystrophy patient receiving
bone marrow transplantation, The Journal of Clinical Investigation,
2002;110(6):807-814.
Spinal Cord Injury
In animal studies cord blood stem cells are beneficial in helping to
reverse paralysis caused by spinal cord injury. Cord blood-derived
stem cells were shown to migrate to and participate in the healing of
neurological defects caused by traumatic assault.

Saporta, S., Kim, J., Willing, A., et al. Human umbilical cord blood
stem cells infusion in spinal cord injury: engraftment and beneficial
influence on behavior. Journal of Hematotherapy & Stem Cell Research.
2003; 12:271-278.
Elly Byrne - 21 Oct 2004 21:53 GMT
Hi Anthony,

Thanks for the reply. I simply went by your email address to see what
you were all about.

Cochlea damage is not aproven fact after drum playing. It is assumed.
Many people have had their hearing return after treatment in Sweden.
http://www.yts.se/english/index.htm

Regards, Elly.

>Thanx for my warm welcome!
>
[quoted text clipped - 16 lines]
>years with positive results and no side effects. The first stem cell bank
>in Africa is also opening in Cape Town soon.

Tinnitus is a pain in the neck
Elly's Tinnitus Resources
http://eebee.net/
 
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