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Medical Forum / Diseases and Disorders / Sinusitis / October 2004

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Nasonex

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Peter H - 09 Oct 2004 15:57 GMT
After more than 6 months of interrupted sleep and sneezing fits/allergy
attacks during the day I went to see my gp on Thursday. I figured that
he'd prescribe flonase but recommended nasonex instead. 2 puffs per
nostril, twice per day.

I started on the spray that night and felt the effect almost
immediately. My sinuses feel like they are teflon-coated. Breathing is
effortless again. I've packed away my claritin.

Last night I slept through the night for the first time in months and
didn't fill 2 or 3 kleenexes when I woke up.

My father, when  alive, was a pharmacist and warned me against these
sprays. He claimed that no one actually knew how they worked or the
possible side effects. I goggled nasonex and his contention was supported.

http://www.biospace.com/ccis/detail.cfm?ClinicalID=332

I don't know how long I'll be on this med but I'm concerned about the
side effects. I suppose I have to balance those side effects with the
obvious side effects of interrupted sleep and constant sinus/allergy
problems during the day.

I also wonder how long the med will be effective. The worst case
scenario would be to continue on this drug until the effectiveness wore
off. Then what?

Anyway, I'm looking for direction from this well-informed group. I'm
sure that many of you have been there and done that and any insight
would be appreciated.

tia

Peter H
Don Brady - 09 Oct 2004 17:28 GMT
>After more than 6 months of interrupted sleep and sneezing fits/allergy
>attacks during the day I went to see my gp on Thursday. I figured that
[quoted text clipped - 18 lines]
>obvious side effects of interrupted sleep and constant sinus/allergy
>problems during the day.

There are normally no side effects at all.  Systemic absorption is only trace
amounts.

It can be taken indefinitely long term.

It does not wear off or cause addiction.

Nasonex is one of the lowest absorbtions of any nasal steroid spray, so it ia
better choice than Flonase for you.

So nasal steroid sprays are actually a better choice than other alternatives
for many people.

>I also wonder how long the med will be effective The worst case
>scenario would be to continue on this drug until the effectiveness wore
[quoted text clipped - 7 lines]
>
>Peter H
ENTconsult - 09 Oct 2004 22:53 GMT
So nasal steroid sprays are actually a better choice than other alternatives
for many people.

yes, the medication goes to your nose and not to your toes like the systemic
stuff.
Good article in AARP on how bad Benadryl is for seniors.
Murray Grossan, M.D.
http://www.ent-consult.com
Pamdomania - 10 Oct 2004 15:17 GMT
>>After more than 6 months of interrupted sleep and sneezing fits/allergy

>>attacks during the day I went to see my gp on Thursday. I figured that

>>he'd prescribe flonase but recommended nasonex instead. 2 puffs per
>>nostril, twice per day.
>>
>>I started on the spray that night and felt the effect almost
>>immediately. My sinuses feel like they are teflon-coated. Breathing is

>>effortless again. I've packed away my claritin.
>>
[quoted text clipped - 27 lines]
>>I also wonder how long the med will be effective The worst case
>>scenario would be to continue on this drug until the effectiveness wore

>>off. Then what?
>>
[quoted text clipped - 5 lines]
>>
>>Peter H

Hello,
You mean like Amphotericin B isnot supposed to be absorbed
into the body when used as a nasal wash? So why did i get
the gout (hyperuricemia (or whatever spelling)) from it?
You need more education on this subject so you best go to here:
www.mall-net.com/mcs/afung.html
www.drmirkin.com/morehealth/G220.htm
As you can see you should stop telling people to take steroids,
because they only hide the symptoms and destroy the body. They
are a destructive, modern-day version of the old-time "Sugar
Pill". Theyhave now become Medicine's Trogon Horse . . . In
the beginning they were to be used (in conjunction with
bonified medication), just long enough to get you:
"over the hump"; now they are an abused drug by laymen as well
as the medical society. They should be taken off the market,
because of this ignorant and diabolical abuse.
+ + + + + + + + + + + + + + + + + + + +
http://www.biblebelievers.org.au/benjamin.htm
MustRead!  http://WWW.PAMINIFARM.COM
"My people are destroyed for lack of knowledge" Hosea 4:6

 
Don Brady - 10 Oct 2004 15:27 GMT
>Hello,
>You mean like Amphotericin B isnot supposed to be absorbed
[quoted text clipped - 3 lines]
>www.mall-net.com/mcs/afung.html
>www.drmirkin.com/morehealth/G220.htm

No I said nothing about Amphotericin B and I have never recommended it.

>As you can see you should stop telling people to take steroids,
>because they only hide the symptoms and destroy the body. They
>are a destructive, modern-day version of the old-time "Sugar
>Pill".

You're failing to distinguish between oral steroids, which do have
side-effects, and nasal steroid sprays , which normally do not.
Pamdomania - 10 Oct 2004 16:22 GMT
>>Hello,
>>You mean like Amphotericin B isnot supposed to be absorbed
[quoted text clipped - 13 lines]
>You're failing to distinguish between oral steroids, which do have
>side-effects, and nasal steroid sprays , which normally do not.

Hello,
Please pay attention this time!!!! Just because "they" say
it willnot be absorbed into the body doesnot in
anywaysahpeorform mean it is the truth, as was
the case with my Amphotericin B experience. I
only gave my case history as an example of the
bullsh!t being fed to us goy. Everything that
even if it only gets on the skin will be absorbed
into the body. Why do you think they tell you
to wear special clothing, bathe, etc. when
you spray insecticides?????!!!!!!!
+ + + + + + + + + + + + + + + + + + + +
http://www.biblebelievers.org.au/benjamin.htm
MustRead!  http://WWW.PAMINIFARM.COM
"My people are destroyed for lack of knowledge" Hosea 4:6

 
Steven D. Litvintchouk - 09 Oct 2004 18:06 GMT
> After more than 6 months of interrupted sleep and sneezing fits/allergy
> attacks during the day I went to see my gp on Thursday. I figured that
[quoted text clipped - 7 lines]
> Last night I slept through the night for the first time in months and
> didn't fill 2 or 3 kleenexes when I woke up.

That's terrific!  I only wish it worked that well for me!  :-)

> My father, when  alive, was a pharmacist and warned me against these
> sprays. He claimed that no one actually knew how they worked or the
> possible side effects. I goggled nasonex and his contention was supported.
>
> http://www.biospace.com/ccis/detail.cfm?ClinicalID=332

Gee, if Nasonex has been approved for pediatric patients as young as two
years old, I would consider that as an indication that it's pretty safe.
   My ENT said it's safe to use it, even if I get a common cold, or
even if I get a *mild* sinus infection.  Its side effect profile isn't
much worse than that of placebo:

http://www.rxlist.com/cgi/generic2/momet1_ad.htm

I've been on meds for long periods, that are a lot less safe than
Nasonex, believe me.  It's a tradeoff each patient has to make for himself.

> I also wonder how long the med will be effective. The worst case
> scenario would be to continue on this drug until the effectiveness wore
> off. Then what?

I've never heard of its effectiveness wearing off over long periods of
time.  I  have heard of inflammation getting so much worse that it can
no longer control the inflammation.  But that should be checked out by a
physician anyway.

Signature

Steven D. Litvintchouk
Email:  sdlitvin@earthlinkNOSPAM.net

Remove the NOSPAM before replying to me.

ENTconsult - 09 Oct 2004 22:51 GMT
Nasonex, Flonase and the others have been heavily used for two decades. Side
effects have been minimal, even in children.
Occasionally there is a nose bleed.  As for effect on the general body, we see
few if any.
One author wrote that all of them are the same, just use the one that is
cheaper.
If you find one that works for you, no reason not to use it.
Murray Grossan, M.D.
http://www.ent-consult.com
beamish - 10 Oct 2004 14:19 GMT
> After more than 6 months of interrupted sleep and sneezing fits/allergy
> attacks during the day I went to see my gp on Thursday. I figured that
[quoted text clipped - 30 lines]
>
> Peter H
Hello, Suggest having a I.O.P test, eye pressure test, several days after
starting nasal spray, inhaler or tablet
that is steroid base.
take care.
beamish.
Peter H - 10 Oct 2004 15:27 GMT
>>After more than 6 months of interrupted sleep and sneezing fits/allergy
>>attacks during the day I went to see my gp on Thursday. I figured that
[quoted text clipped - 36 lines]
> take care.
> beamish.

Hi Beamish: I've done a search and have found no reports of a connection
between Nasonex and glaucoma. I'm curious as to why you would recommend
an IOP Test.

Peter H
Don Brady - 10 Oct 2004 15:41 GMT
>Hi Beamish: I've done a search and have found no reports of a connection
>between Nasonex and glaucoma. I'm curious as to why you would recommend
>an IOP Test.

Oral steroids can raise IOP, and marginally inhaled steroids slightlly, but the
studies show that nasal steroid sprays do not, especially Nasonex, which has
the lowest systemic absorption.

But it never hurts do know your IOP's anyway.  I think everyone should, along
with their cholesterol and blood pressure levels.
beamish - 10 Oct 2004 16:45 GMT
>>Hi Beamish: I've done a search and have found no reports of a connection
>>between Nasonex and glaucoma. I'm curious as to why you would recommend
[quoted text clipped - 9 lines]
> along
> with their cholesterol and blood pressure levels.
Hello, Agree with your last paragraph.
Some question concerning second paragraph and the individual. In my case my
basic I.O.P., before health problems and use of medication, was close to the
beginning of the danger zone.
Do to a  new problem concerning sinus inflammation tried several different
nasal sprays for sinus problem, some had no useful effect some caused
increased occular pressure. Just a 2 point increase but thereby placing me
in a danger zone and the need for eye drops to lower the pressure. If my
Doctor had not ask me to have my eyes checked I very well could have had a
more serious issue concerning my sight.
When I visit a doctor I remind myself that I am an individual and may have a
different response then the average to medication. This is most important
when there are several meds. involved. So I do follow your last paragraph
everytime my meds. are changed.
Take Care.
beamish.
Don Brady - 10 Oct 2004 19:23 GMT
>Hello, Agree with your last paragraph.
>Some question concerning second paragraph and the individual. In my case my
[quoted text clipped - 4 lines]
>increased occular pressure. Just a 2 point increase but thereby placing me
>in a danger zone and the need for eye drops to lower the pressure. If my

Yes actually these danger points are just arbitrarily chosen statistically at
x% etc., but then again I suppose they have to have some number.

Sme people can have low IOP's and still get glaucoma.  Others can have high
IOP's and no glaucoma.   A field test is important.

Still, better safe than sorry.....

>Doctor had not ask me to have my eyes checked I very well could have had a
>more serious issue concerning my sight.
[quoted text clipped - 4 lines]
>Take Care.
>beamish.
ENTconsult - 11 Oct 2004 19:58 GMT
My father, when  alive, was a pharmacist and warned me against these
>>sprays. He claimed that no one actually knew how they worked or the
>>possible side effects. I goggled nasonex and his contention was supported.

It is true that years ago there was considerable question re safety over long
periods of time. At that time your father was right.
But now, two decades later and according to the 2004 Rhinology meeting the
systemic side effects are negligeable and simply have not been shown to be a
factor requireing cessation of treatment.
You can get nosebleed and thinning of nasal membranes, but that is treatable.
You don't get addiction , nervousness, and the drug goes to your nose and not
to your toes.
Of course you don't want to use it if you can avoid it , and the stuff costs
money.
Murray Grossan, M.D.
http://www.ent-consult.com
Pamdomania - 10 Oct 2004 14:51 GMT
>After more than 6 months of interrupted sleep and sneezing fits/allergy

>attacks during the day I went to see my gp on Thursday. I figured that
>he'd prescribe flonase but recommended nasonex instead. 2 puffs per
[quoted text clipped - 20 lines]
>I also wonder how long the med will be effective. The worst case
>scenario would be to continue on this drug until the effectiveness wore

>off. Then what?
>
[quoted text clipped - 5 lines]
>
>Peter H

Hello,
Get rid of the kitty-litter box and bird cages etc:
You could start with air filters and cleaners; also O-zone
bulbs are cheap for a starter until you can afford the O-zone
generator (cost about $700.00); then there is this or bust:
www.mall-net.com/mcs/afung.html
(not to mention this):
www.drmirkin.com/morehealth/G220.htm
(and this):
Remember the "Saying":
Where there is irritation;
There is blockage;
Where there is blockage;
There is swelling;
Where there is swelling;
There is infection.
+ + + + + + + + + + + + + + + + + + + +
http://www.biblebelievers.org.au/benjamin.htm
MustRead!  http://WWW.PAMINIFARM.COM
"My people are destroyed for lack of knowledge" Hosea 4:6

 
 
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