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Medical Forum / Diseases and Disorders / Sinusitis / September 2004

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MCC - anyone know what that abbreviation means?

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iJah - 22 Sep 2004 15:38 GMT
Still digging for a definition of the abbreviation MCC. There is a
reference to 'MCC disorder'. I'm guessing it has to do with cilia, but
can't figure it out exactly.

Here's the context I have been reading about it in on Dr. Grossans
site (which most of the links seem to be broken on now - I'm doing all
my reading from Google's cached pages)...

**********
Pathologic effects of dust exposure may include *MCC disorder*, and
disturbance of regional immunity and the acid-base balance of tissues.
These are reported by to be in direct proportion to the length of
exposure to excessive dirt and dust.

The Kuwait oil fires released polyelie aromatic hydrocarbons and
nickel and vanadium into the atmosphere. Results of this contamination
are now being studied with indications of effects on MCC. and an
increase in respiratory infections.

Formalin vapor and solutions below 0.25 % will inhibit MCC and cause
symptoms. Chromium and chromates are known to be ciliotoxic and
harmful to workers in mining and industry. In addition, certain areas
of Saudi Arabia have chromium in the sand with an associated high
incidence of sinus disease and chest disease. Workers in plating and
sanding industries should wear protective inhalers and use pulsating
saline irrigation to remove these chemicals and help restore the nasal
ciliary action.

Smoking does not give consistent results, even in the laboratory. One
interesting phenomenon is the patient who has swollen nasal membranes
after he stops smoking. Some patients return to smoking to overcome
the congestion and blockage. What may be the mechanism here is that
the smoke acted as an irritant to the cilia, inducing movement. With
the cessation of smoking, the stimulus is reduced and the cilia stop,
leading to the feeling of obstruction.. In these patients I find
decreased MCC and they respond to measures to restore normal MCC.
ENTconsult - 25 Sep 2004 04:03 GMT
MCC usually means mucociliary clearance. refers to movement of the nasal cilia,
moving the mucus blanket. It can be measured with saccharin as per my web site.

Murray Grossan, M.D.
http://www.ent-consult.com
 
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