According to http://www.sinofresh.com/content/clinicaloverview.aspx

 
Clinical Overview

What is SinoFresh?

SinoFresh is a topical antiseptic nasal spray effective against the molds and
bacteria that are most commonly associated with "Rhinosinusitis."  The need for
an effective topical antimicrobial in nasal and sinus disease is well
documented because, despite extended courses of systemic therapy, the spectrum
of persistent bacteria and fungi in the nose and sinus is extensive.  It is the
persistent extra mucosal colonization that allows these organisms to function
as "living antigens," triggering lgG, lgE, and neutrophil medicated
inflammatory reactions.  No other agent attacks the cause of the inflammatory
response except for the dilutional effect of saline irrigation.  SinoFresh has
been shown to kill these organisms, essentially on contact.  SinoFresh, 1-3
sprays twice daily, is used as a daily antiseptic nasal hygiene regiment in
patients with chronic nasal and sinus symptoms and in patients who simply
desire a refreshing cleansing of the accessible nasal and sinus mucosa.

What is CPC?

The active ingredient in SinoFresh is a surface active cationic antiseptic,
Cetylpyridinium Chloride (CPC), with antimicrobial activity against bacteria,
fungi, and viruses.  CPC has been used in oral rinse products for over fifty
years and it`s safety has been documented extensively.  It has been formulated
into topical nasal spray, along with moisturizers and mint aromatics, to be
used as a nasal hygiene product.  In Intranasal safety studies to date, and
national chain store distribution, there have been no significant adverse side
effects reported.  SinoFresh can also be used in conjunction with other
traditional medications without adverse reactions.  The total monthly dose of
CPC in SinoFresh is less than typical daily dose of an oral rinse product
containing CPC.  Its surface active properties and proven safety profile in
mucosal applications makes it an ideal agent for intranasal topical use.  The
intact SinoFresh product containing .05% CPC was tested in vitro against a
spectrum of bacteria and fungal organisms known to be present in rhinosinusitis
and was found to be both bactericidal and fungicidal, essentially on contact.
Swabs of the middle meatus taken before and after twice daily SinoFresh use has
show clearance of pathogens in as little as 4 days in initial studies.  A
visible reduction in nasal mucosal swelling accompanied this antimicorbial
response.

Organisms Killed by SinoFresh in vitro:*

      Bacteria

Haemophilus Influenzae
Moraxella Cattarrhalis
Streptotoccus Pyogenes
Staphlococcus Aureus
MRSA Species
Psudomonas Aeruginosa
Escherichia Coli
     Fungal Species-inhaled molds

Candida Albicans
Aspergillus Niger
Cladosporium Herbarum
Alternaria Alternata
Pennicillium Finiculosum
Fusarium Solani
Strachyboytris Chartarum
Who My Benefit From SinoFresh Use?

Patients with Chronic non-allergic nasal and sinus symptoms
Mold-allergic and sensitive patients
Fetid breath or nasal odor
Snoring
Travelers
People in close contact with the public
Patients with Chronic recurrent rhinosinusitis unresponsive to systemic
therapy**
*    USP Quantitative mini-kill time test - Nelson Laboratories, Salt Lake City

**  These patients may benefit from twice daily antiseptic cleansing of the
nose and sinuses.  Not intended as a treatment or proven preventive therapy of
any medical condition.

Active Ingredients:
Cetylpyridinium chloride 0.5%

Inactive Ingredients:
Benzalkonium chloride, dibasic sodium phosphate, eucalyptus oil,
monobasic sodium phosphate, peppermint oil, polysorbate 80, propylene
glycol, purified water, sodium chloride, sorbitol solution, spearmint
oil and wintergreen oil.