Yes.  I've been irrigating with the Grossan Irrigator for about
2 years now.  My wife irrigates with the Grossan tip connected
to a Water Pic ( don't know the model off top of my head ).  I
had to finagle the irrigator tip to fit/work on her model of water
pic -- it works fine the way I've done it.  You can get Water Pics
that will accept the tip with no fanagling.

I've not used Alkahol; I've heard of it.  I've used
BreathEase -- it works nicely.  But I mostly use my own homemade
saline solution ( 1 tsp kosher salt / 1/2 tsp baking soda in 16 oz
of distilled water ).  Its works perfectly.   Use the BreathEase to
"fix" the cilia and then regular saline to maintain the sinuses ...

I tried Alkalol (that's how you spell it) for a while.  But my nose was
sensitive to it, even at a low dilution, so I stopped it.

If you can tolerate it, it works well.

-- Steven L.