I am 45 and have had sinusitis since 1998. Three operations to remove
polyps, reduce turbinates, open up airways etc.
Plenty of sinus infections along the way. Before, they would go away
with antibiotics and I was able to carry on.
Now, I am developing a lot of antibiotic resistance and the effect of
the antibiotics is much less. Now the infections are more frequent and
very violent, take much longer to clear and go down to my chest. It
gets very bad.
I am now fighting an infection of Streptococcus pneumoniae. It is
resistant to plenty of antibiotics but sensitive to Augmentin (co-
amoxiclav) and to Moxifloxacin according to the cultures.
Two months ago I also had Streptococcus pneumoniae and Augmentin
killed it very well after a week and a half on it.
Now, I have been on Augmentin for two weeks but it did not clear.
Consequently, I have started Moxifloxacin but after three days on it I
do not see it working either. I know it may seem too early to say,
but, in general, I can tell when it is going to work or not very early
on.
My main problem is always my chest. It hurts like burning or feeling
very cold inside, in the mornings I produce infected sputum. When I do
not have an infection my chest is fine and stays fine for a few days
while I develop a sinus infection.
All this boils down to not being able to drain my sinuses properly.
Whenever I am well and my sinuses are draining everything is fine. As
soon as they stop draining, a few days later I develop a sinus
infection.
I do everything, nasal douche, steroid nasules, vapour, good food, no
smoking, good habits, sports when well, etc.
My immune system is not very strong but within normality.
I just need someone to help me drain or keep my sinuses from getting
clogged.
I am in London, UK my ENTs here have given up. They say no further
surgery options are available and the only option is antibiotics.
Since I think I can afford it, I am willing to go to the US or
anywhere else in search for the best clinic/doctor for cases like
mine.
I know that it won't likely make a difference, but I am running out of
options.
Thanks,
Antonio
Steven L. - 26 Apr 2008 01:26 GMT
> I am 45 and have had sinusitis since 1998. Three operations to remove
> polyps, reduce turbinates, open up airways etc.
[quoted text clipped - 6 lines]
> very violent, take much longer to clear and go down to my chest. It
> gets very bad.
Yes, I know the story. I was the same way. :-(
> My immune system is not very strong but within normality.
>
[quoted text clipped - 10 lines]
> I know that it won't likely make a difference, but I am running out of
> options.
After 3 operations, you may need to try something different. I don't
know what else has been done for you.
You could try to see Dr. Wellington Tichenor in New York City. He's
familiar with the latest research on non-surgical treatment
methods--immunology, gamma globulin, intravenous antibiotics, etc. I'm
considering making an appointment to see him myself:
http://www.sinuses.com/
and
http://www.sinuses.com/postsurg.htm
Another place to try is the Mayo Clinic in Minnesota. They have done
the pioneering work on Allergic Fungal Sinusitis (AFS):
http://www.mayoclinic.com/
If you wish to go there, don't go there in the winter time. Minnesota
is incredibly cold and snowy in the winter.
Make sure that whichever physicians you see are familiar with the
techniques of revision surgery. You've had enough operations already
that the usual anatomical landmarks have been obliterated. That
requires a so-called "revision surgeon," who knows how to find his way
through sinuses that have already been previously operated on.
BTW, with the weak dollar these days, you ought to be able to find even
New York City quite affordable. I used to live there; so if you need
tips on housing or sightseeing, please ask. You might as well make a
vacation out of it!
The last-resort option you have is relocation to a warmer, less polluted
climate. Many folks with sinusitis, myself included, can simply no
longer stand to live in major cities like downtown Boston or London. I
had a co-worker who immigrated to America from Egypt. In Egypt, the air
is warm and dry and less polluted; here in Boston it's cold and damp and
polluted, and he's miserable here. Maybe you could try moving to the
tropics--or at least taking long vacations down there.
Good luck.

Signature
Steven L.
Email: sdlitvin@earthlinkNOSPAM.net
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errfrsdaf - 26 Apr 2008 03:15 GMT
> I am 45 and have had sinusitis since 1998. Three operations to remove
> polyps, reduce turbinates, open up airways etc.
<snip>
Been there...
> I know that it won't likely make a difference, but I am running out of
> options.
A massive, and I mean MASSIVE difference for me was nasal lavage with
pulmicort respules. I went to my ent to schedule a 3rd surgery. I
was absolutely terrible. 100% smell lose and 95-100% clogged all the
time. I just about said yes to schedule the surgery but then I asked
him about irrigation with pulmicort. He said he never heard of doing
that but was willing to let me try. He calls me his "poster boy" for
nasal polyps. So I tried it. I use an 8oz neilmed bottle with salt
only. I use up about 7oz of saline then dump in the pulmicort.
I pump each side of my sinuses full and then stand there bent over
with the top of my head facing the floor for five minutes. Then
let it drain out and go to bed. It's been several months now and
for the first time in years I can smell again and always have 80-100%
clear sinuses. I do not kid you when I say it totally changed my
life. If you are this bad you have to try it.
** Posted from http://www.teranews.com **
neil0502@yahoo.com - 28 Apr 2008 15:02 GMT
Have you considered/discussed with your ENT going on low-dose
macrolides (a class of antibiotic) for 3-6 months (or more)?
If you search this newsgroup, you'll find additional info on why
macrolides, in theory, make so much sense. Resistance doesn't /seem/
to be a problem at these low (sub-clinical) doses.
Best of luck.
Antonio - 30 Apr 2008 10:57 GMT
On 28 Apr, 15:02, neil0...@yahoo.com wrote:
> Have you considered/discussed with your ENT going on low-dose
> macrolides (a class of antibiotic) for 3-6 months (or more)?
[quoted text clipped - 4 lines]
>
> Best of luck.
Yes, I've done that.
I was on a normal to small dose of Clarithromycin for about a year.
Everything went well until I developed a big infection while on
Clarithromycin.
Later on I tried Azithromycin 500mg once a week, along with steroid
drops. It went well for a while but after a few months it stopped
working.
Needless to say that my bugs are now resistant to both antibiotics.
truehawk - 01 May 2008 03:08 GMT
> On 28 Apr, 15:02, neil0...@yahoo.com wrote:
>
[quoted text clipped - 18 lines]
>
> Needless to say that my bugs are now resistant to both antibiotics.
Phages
Bugs that kill the bugs.
Were I in your position, I would go to Tbilisi.
http://www.phagetherapycenter.com/pii/PatientServlet?command=static_home
Antonio - 01 May 2008 21:22 GMT
> > On 28 Apr, 15:02, neil0...@yahoo.com wrote:
>
[quoted text clipped - 24 lines]
>
> - Show quoted text -
Wow, that is certainly interesting.
Do you know anybody that has gone there?
Many thanks,
Antonio
truehawk - 02 May 2008 01:14 GMT
> > > On 28 Apr, 15:02, neil0...@yahoo.com wrote:
>
[quoted text clipped - 32 lines]
>
> Antonio
No I do not personally know anyone who has been there.
I talked, I think to the company CEO, who had a child cured of staph
there, and later to Christopher Smith who is their US information rep
asking when they were going to open the clinic in Mexico.
The descriptions and explanations of the bacteriology techniques used
track with those that I have found effective make me think that the
Russians are better at bacteriology because they don't use speed
cultures and are patient and more careful observers. In fact I think
Kim Lewis at U Penn is actually from Russia.
Call um and see what you think. I just went to the "about us" page and
dialed until I got a live person on the phone.