Medical Forum / Diseases and Disorders / Sinusitis / July 2008
Sinus Problems...still
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LooLoo - 24 Apr 2008 01:28 GMT I am looking for any advice or moral support! Here is my background. Sinus surgery in about 2000 to remove polyps, open up, etc. Went OK. Second sinus surger in November 2007...removed more polyps, clean/open up, fix mild deviated septum. I have had a (not sure how to spell it) staphoccocus aureas positive infection since Christmas 2007. At one point, I had strep and staph infection in my sinuses. I have been on antibiotics almost non stop since December 2007. Names I can remember are amoxicillan, augmentin, zithromax, ceftin, keflex, levoquin, clindamyacin and also gentamyacin nasal rinse and a anti-fungal med injected in my nose. I have also taken seveal medrol dose packs and a kenalog injection. I may have missed a few meds in the list, not sure. I just can't kick this staph infection. Any suggestions? A friend of mine suggested I persue IV antibiotic...not sure what that means. What med would you suggest next???? My face under the eyes an cheek are throbs and hurts all the time, feels like a was hit in the face. My front teeth throb as well. The pain subsides with some treatment but starts again when the pills are done. I have had numerous sinus cultures done over the past several months. Any help is greatlly appreciated!
Steven L. - 24 Apr 2008 02:25 GMT > I am looking for any advice or moral support! Here is my background. Sinus > surgery in about 2000 to remove polyps, open up, etc. Went OK. Second sinus [quoted text clipped - 14 lines] > past several months. > Any help is greatlly appreciated! Have you had a sinus culture taken from the ducts of your sinuses?
You should have a complete immunological workup to see if your immune system is functioning properly.
You should be tested for mycoplasma infection in your sinuses.
You should be tested for HIV if you're sexually active.
Question: How did your sinus problems start in the first place? Did they start when you were an adult or a child? Was the onset sudden? Did it start after some major change to your lifestyle (relocation, etc.?)? If so, then maybe you need some lifestyle changes. Relocation helped me a lot.
 Signature Steven L. Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
LooLoo - 24 Apr 2008 02:58 GMT My immune system is on the lower end of normal. I have had issues for several years. It just seems that I cannot get rid of this specific infection for sme reason. What is mycoplasma infection? I will get another culture this week. So far, each culture was staph.....
>> I am looking for any advice or moral support! Here is my background. Sinus >> surgery in about 2000 to remove polyps, open up, etc. Went OK. Second sinus [quoted text clipped - 16 lines] >etc.?)? If so, then maybe you need some lifestyle changes. Relocation >helped me a lot. Steven L. - 24 Apr 2008 06:29 GMT > My immune system is on the lower end of normal. I have had issues for > several years. You might be a candidate for immunoglobulin therapy. Consult a qualified immunologist (NOT a glorified allergist).
> It just seems that I cannot get rid of this specific > infection for sme reason. What is mycoplasma infection? go here: http://www.sinuses.com/NTMabstract.htm or here: http://abclocal.go.com/wabc/story?section=news/local&id=6046064
> I will get another culture this week. So far, each culture was staph..... You might be a candidate for vancomycin, the "last resort" antibiotic. Consult an infectious disease specialist.
 Signature Steven L. Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
truehawk - 24 Apr 2008 07:35 GMT > > My immune system is on the lower end of normal. I have had issues for > > several years. [quoted text clipped - 17 lines] > Email: sdlit...@earthlinkNOSPAM.net > Remove the NOSPAM before replying to me. Search the list for "tannin" and read the messages you find there.
I have staph in my sinuses that has had the same sensitivity profile to antibiotics since 2001.
According to it's MICs it should have been wiped out LONG ago as the antibiotics that I have been given wipe out the lab culture. The worst part of it, since i got rid of enough of it to be able to breath at night, has been the extreame heartburn that it causes if I don't treat it with prilosec or pepsid. Staph is sufficient by itself to persist once it establishes a biofilm, and it is NEVER there alone. Chronic sinusitis is a disease caused by bacteria that get a foothold any time that you have had the flu and have accumulated in your air filter over a life time. It was also suggested that I might be immune deficient, but my immune system is just dandy. It only needs a spot where a virus has killed the cilia to move on in. Staph also produces an enzyme that allows it to spread the walls of blood cells to make them weep blood and coagulese that converts fibernectin to fibrin so ti can make it's biofilm, that clear insoluible springy mucus, at practically no metabolic cost and it destroys trans membrane conductance factor, so it upsets the osmotic balance of epitihieal cells in a way that leads to less fluid to wash away the mucus. tea and Mupricin,and canada balsam washes are somewhat effective in reducing it's footprint. Also the Soviet government has refined and used Lysic phages (viruses) that kill staph for the last 50 years if you can get over there. There was one lady that went over because she had had multiple surgeries and was told that she had stomach cancer and only 6 months to live, she also had arthritis, DM, and a whole list of other symptoms . When here sinus infection was treated, all her other symptoms cleared up too. I called her and she said that she had had to go over twice to Georgia twice, but was now disease free. Her treatment cost 15,000 which included airfare, 2-3 week stays in Tbilize, and her treatments. The hospital is evidently falling down around their ears, but the people and the technologies are still there. http://www.phagetherapycenter.com/pii/PatientServlet?command=static_home&secnavp os=-1&language=0 The knock on phage therapy is that the proper doubleblind placebo controlled trials have not been done. The soviets gave it to people on one side of the street, and everyone on both sides of the street got well. Recently experiments in this country have used phages adhered to plastic beads so they can't get away and cure people that have not paid for it, so we might see them in this country before too long.
Fred - 25 Apr 2008 02:24 GMT > I am looking for any advice or moral support! �Here is my background. �Sinus > surgery in about 2000 to remove polyps, open up, etc. �Went OK. �Second sinus [quoted text clipped - 14 lines] > past several months. > Any help is greatlly appreciated! How are you sleeping? Any sleep apnea. If you don't sleep well, you immune system is depressed because during your sleep, cortisone is produced. Cortisone is the hormone that enables your body to heal. Maybe that and an increased amount of nasal washes to get some of the infection out.
LooLoo - 25 Apr 2008 02:55 GMT No sleep apnea that I know of. I looked at my last culture report. The staph infection is resistent to penicillin and erythromycin. I had another cuture today so we will see what that is. As I type, my face is throbbing! Maybe I should just quite all antibiotics and just sit it out????
>> I am looking for any advice or moral support! �Here is my background. �Sinus >> surgery in about 2000 to remove polyps, open up, etc. �Went OK. �Second sinus [quoted text clipped - 7 lines] >Maybe that and an increased amount of nasal washes to get some of the >infection out. truehawk - 25 Apr 2008 04:35 GMT > No sleep apnea that I know of. I looked at my last culture report. The > staph infection is resistent to penicillin and erythromycin. I had another [quoted text clipped - 15 lines] > -- > Message posted via MedKB.comhttp://www.medkb.com/Uwe/Forums.aspx/sinusitis/200804/1 I know that you feel terrible. This stufff manufactures toxins that stun and kill immune cells and I think the CNS effects of those toxins are grogginess, aphasia and depression. You, your consciousness and your intelligence are part of your immune system the mindful part.. You could quit all antibiotics, or you could do some research and resolve to kill it before it strangles the joy of life out of you. There are combinations of antibiotics and antifungals that work, specificly a macrolide such as biaxin to cover the staph, combined with sporanox to cover the fungi, and bactrium to cover the actinomycetes all at once and together and for a minimum of a month, along with tannin washes to wash our the fibrin mucus. But Hey, Your nose, your life, your choice.
LooLoo - 19 Jul 2008 02:08 GMT I am still having the same problems...however I now have psuedonoma some kind of infection? any thoughts?
>> No sleep apnea that I know of. I looked at my last culture report. The >> staph infection is resistent to penicillin and erythromycin. I had another [quoted text clipped - 14 lines] >along with tannin washes to wash our the fibrin mucus. >But Hey, Your nose, your life, your choice.
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