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Medical Forum / Diseases and Disorders / Sinusitis / February 2008

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Zoloft and sinusitis?

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marko.borovec@gmail.com - 14 Feb 2008 21:24 GMT
Hi. First I was on Zoloft for 2 years and I had hardly any side
effects. Then I stopped using Zoloft and switched to Effexor for 6
months. 3 months ago I started using Zoloft again and since then I
have developed sinusitis that I can't get rid off. Symptoms I
experience are slight fever, headache and stuffed nose. My doctor says
this is some kind of allergic reaction that lasts for 3 months. My
question is this. Could my allergy and my symptoms be causes by
Zoloft? I read somewhere that you can get rashes or similar things
from Zoloft but fever and stuffed nose? Is this possible? Can this two
be connected? Thanks.
neil0502@yahoo.com - 14 Feb 2008 22:03 GMT
On Feb 14, 1:24 pm, marko.boro...@gmail.com wrote:
> Hi. First I was on Zoloft for 2 years and I had hardly any side
> effects. Then I stopped using Zoloft and switched to Effexor for 6
[quoted text clipped - 6 lines]
> from Zoloft but fever and stuffed nose? Is this possible? Can this two
> be connected? Thanks.

Well ...

If you believe the manufacturers own prescribing information:

http://www.zoloft.com/pdf/ZoloftUSPI.pdf

Sinusitis is listed as a known side effect.

It's listed as "infrequent," where "infrequent" is defined as between
1 in 100 and 1 in 1000 patients.

I'd say ... it got you.

You could switch meds, or you could work through it, hoping it goes
away, and trying to battle the sinus issues as symptoms until it
either DOES resolve ... or you decide to switch meds ;-)

I gotta' tell you: Rx meds can be awfully scary.  Before I take
anything, I google:

[insert drug name] prescribing information filetype:pdf

The original insert is almost ALWAYS a .pdf file.  This narrows the
search.

Good luck!
truehawk - 15 Feb 2008 02:44 GMT
On Feb 14, 5:03 pm, neil0...@yahoo.com wrote:
> On Feb 14, 1:24 pm, marko.boro...@gmail.com wrote:
>
[quoted text clipped - 35 lines]
>
> Good luck!

I don't know.
Most antidepressents started life as antihistimines and share many of
the characteristics of antihistimines, dry mouth being one of the most
common side effects. Bacteria, the wee beasties produce antigens to
make the cell express mannose on the cell surface that they can attach
to, and they use other toxins which are analogs of histamines to make
the wound that they create bleed so that they can chow down.
Antihistimines tend to reduce the amount of tears, saliva, the output
of nasal goblet cells, and the inflammation caused by the bacterial
bunch.
Reducing the output of nasal fluid tears and saliva would be bad,
reducing the inflammation would reduce the bacterial food supply and
be good.  It would depend on which phenomena  is dominate.
neil0502@yahoo.com - 15 Feb 2008 03:17 GMT
> On Feb 14, 5:03 pm, neil0...@yahoo.com wrote:
>
[quoted text clipped - 45 lines]
> to, and they use other toxins which are analogs of histamines to make
> the wound that they create bleed so that they can chow down.

Elizabeth,

You gross me out.  I like you.
truehawk - 15 Feb 2008 05:36 GMT
On Feb 14, 10:17 pm, neil0...@yahoo.com wrote:

> > On Feb 14, 5:03 pm, neil0...@yahoo.com wrote:
>
[quoted text clipped - 49 lines]
>
> You gross me out.  I like you.

Neil:
Thank you.  I like you too.
I too wonder if the baby shampoo makes the nasal hair arrange itself
in attractive curls.

I also wonder if your dry eye might have something to do with chronic
antihistamine use.
I know dental carries are one of the side effects of the dry mouth
that they cause. But fluoridation and
restorative dental rinses have made that not so much of an issue as
long as one is careful.  I never thought about
the possibility of dry eye.
neil0502@yahoo.com - 15 Feb 2008 07:25 GMT
> I also wonder if your dry eye might have something to do with chronic
> antihistamine use.

I stayed way away from antihistamines for as long as I can recall,
resorting to decongestants on occasion.

Only ever dabbled in the anti-depressants over the years, too.  I
found that having ... just a touch of depression ... made me a little
dark, complex, edgy, and mysterious.

It worked out well in the dating arena ;-)

> I know dental carries are one of the side effects of the dry mouth
> that they cause. But fluoridation and
> restorative dental rinses have made that not so much of an issue as
> long as one is careful.

Too true.  Sjogren's people have to worry about this.

> I never thought about
> the possibility of dry eye.

It's /absolutely/ an aggravating factor AND a side effect that LOTS of
severe DES (Drye Eye Syndrome) folk have to be aware of.  Sadly, like
lots of things in our world, I've known quite a few people for whom
the extra severity was worth it for the extra "coping bandwidth" they
derived.

Mayo had me on two diff tricyclics for the neuropathic pain, but ...
though BOTH have all the usual adverse effects listed ... I didn't
have any particular problem with either.  I gave them up (I usually
say "for Lent," but ... I think it just WAS Lent, so ... it wouldn't
be so cute!).

It SEEMS like my ocular surface disorder was bought and paid for by
the 6.5+ years of cycloplegics, particularly because they were all
preserved with that lovely and fragrant quaternary ammonium ...
Benzalkonium Chloride.  Allegedly, the "signature" found under the
confocal microscopy was a match.
marko.borovec@gmail.com - 15 Feb 2008 16:12 GMT
I will switch my medication. From Zoloft to Effexor. I will do this
with doctors approval. I will inform you how it goes with my
sinusitis.
Murray Grossan - 15 Feb 2008 04:52 GMT
On 2/14/08 2:03 PM, in article
3eb93ffb-8c3d-4278-846c-00646efe5872@i7g2000prf.googlegroups.com,

> On Feb 14, 1:24 pm, marko.boro...@gmail.com wrote:
>> Hi. First I was on Zoloft for 2 years and I had hardly any side
[quoted text clipped - 34 lines]
>
> Good luck!
The sad thing about the PDR and the package insert is they list every
complication they can think of or that the lawyers can think of. The doctor
sees the same list for every drug. It is only when you go to meetings and
speak to other doctors that you find out what the real genuine side effects
are.
I have prescribed Chlortimeton for 35+ years at least 5x a day. I have never
heard of or seen most of the side effects they list, but the important side
effects are burried in that long many page list. Again, the important side
effects of the newer drugs are burried in that same 101 list.
truehawk - 15 Feb 2008 06:01 GMT
> On 2/14/08 2:03 PM, in article
> 3eb93ffb-8c3d-4278-846c-00646efe5...@i7g2000prf.googlegroups.com,
[quoted text clipped - 48 lines]
> effects are burried in that long many page list. Again, the important side
> effects of the newer drugs are burried in that same 101 list.

Doc:
I have taken a truck load of antihistimines and was grateful for them
when I did.
But I developed intense, blinding headaches.
After years and years an internist in Lancaster Ca told me
to stop the Drixoral and use some Americane ointment on a swab up
under the bridge of my nose,
put me on Bactrium, and low and behold the headaches stopped.
Steven L. - 15 Feb 2008 21:47 GMT
> Hi. First I was on Zoloft for 2 years and I had hardly any side
> effects. Then I stopped using Zoloft and switched to Effexor for 6
[quoted text clipped - 6 lines]
> from Zoloft but fever and stuffed nose? Is this possible? Can this two
> be connected?

Many antidepressants and antipsychotics have a drying effect, which can
thicken mucus secretions and promote sinusitis.

Generally, it seems to correlate with the drugs that cause drowsiness as
a side effect.  If you're on an antidepressant like Paxil that makes you
drowsy, it probably is drying out your mucous membranes too.

Signature

Steven L.
Email:  sdlitvin@earthlinkNOSPAM.net
Remove the NOSPAM before replying to me.


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