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Medical Forum / Diseases and Disorders / Sinusitis / February 2008

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How often do you irrigate?

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dolysods@yahoo.com - 10 Feb 2008 16:21 GMT
after getting back a sinus infection (urgent care doc only gave me a
zpak),  i was miserable enough to get a neti pot and try it out.  I
definitely feel better after using it.  I just got a neti pot kit.  It
has the salt and some neti wash stuff to put in it.  I haven't used
that yet. Some have talked about baking soda.. how much?

how often?

thanks..hoping omnicef will kick out the infection this time

Tracey
Susan - 10 Feb 2008 17:11 GMT
> after getting back a sinus infection (urgent care doc only gave me a
> zpak),  i was miserable enough to get a neti pot and try it out.  I
[quoted text clipped - 7 lines]
>
> Tracey

I used to have to irrigate daily just to keep a low level of infection,
even while on antibiotics.  During colds, I irrigated two or three times
per day, very gently.

Since taking a very high dose of vit D3 a while back, I only have
irrigated when congested by allergy, or experiencing drip, like 2 times
per week. I've not felt nor seen significant signs of infection since
using D3, nor has my sister, who experienced the same sudden drainage
from her infected sinus about an hour after taking 10,000iu of vitamin
D3 in a gel cap.  It WORKS, folks, just the way I'd read about.

Honorable mention to Elizabeth/Truehawk for the black tea irrigation
suggestion; I was congested twice from allergy (needed to clean my room
humidifier) and the tea with saline solution *really* causes a lot of
drainage and seems to dry out the nose and sinus.  I just flew to and
from FL with no sinus worsening, too.

I strongly recommend weekly high doses of D3 gel caps for a few weeks
and the tea irrigation solution.

Susan
aroberts - 10 Feb 2008 18:37 GMT
> x-no-archive: yes
>
[quoted text clipped - 31 lines]
>
> Susan

This is interesting, and it makes sense that D3 would open things up--it's a
secosteroid--related to prednisone. To be clear, are you dosing 10,000iu
once a week?

I know that the Food and Nutrition board set the UL of vit D extremely
conservatively (some would argue paranoically) low at 2000iu.

Thanks.
dolysods@yahoo.com - 10 Feb 2008 19:24 GMT
Interesting... i have some sublingual D3. Haven't had it out in a
while

> > x-no-archive: yes
>
[quoted text clipped - 41 lines]
>
> Thanks.
Susan - 10 Feb 2008 21:56 GMT
> Interesting... i have some sublingual D3. Haven't had it out in a
> while

The only recommended form of D3 I know of is the gel caps.

Susan
Michael - 11 Feb 2008 08:59 GMT
> x-no-archive: yes
>
[quoted text clipped - 5 lines]
>
> Susan

"I've not felt nor seen significant signs of infection since
using D3, nor has my sister, who experienced the same sudden drainage
from her infected sinus about an hour after taking 10,000iu of vitamin
D3 in a gel cap.  It WORKS, folks, just the way I'd read about. "

Susan:

I read your inspiring initial posts: it has not worked for me, alas.

After reading the literature & suggestions of the Vit. D Council
tried the following: 100,000 i.u. for 3 days followed by 10,000 i.u.
per day for 30 days.  All were in cap form from a supplier recommended
by the Vit. D Council.

[To explain my apparently eccentric high dosage: 2.5 mg (for vit D =
100,000 i.u.) was the single dose used in this TB trial (
http://ajrccm.atsjournals.org/cgi/content/abstract/176/2/208 ) and had
to be safe (singe dosages of  300,000 i.u., are used in Europe to
counteract deficiency); vit D daily consumption appears to be +/-
4,800 i.u. ; vit D production from sun exposure appears to  cut off at
+/- 20,000 i.u. per day.  Therefore, even following the thee day of
'super dosing' the  daily dose of 10,000 did not seem, to me, to be
risking toxicity.]

Michael
Susan - 11 Feb 2008 14:48 GMT
> Susan:
>
[quoted text clipped - 14 lines]
> 'super dosing' the  daily dose of 10,000 did not seem, to me, to be
> risking toxicity.]

Michael, vit D can both up or down regulate your immunity.  Those doses
are for deficiency.  If you don't have deficiency, they'll suppress you.
Is it possible that's what happened here?

Also, my sister and I both get strong allergy desensitization shots and
use encasements and air cleaners in our rooms, etc.

Sorry if you got no bang for your buck, but I'd drop that dose unless
you're having serology coming back with 25(OH)D deficiency documented.

Susan
Michael - 12 Feb 2008 01:13 GMT
> x-no-archive: yes
>
[quoted text clipped - 28 lines]
>
> Susan

Thanks Susan.

I am almost certain I am deficient (have been on prednisone 10 mg.
every other day for the last year, the prior year was daily dose).
The effect of the prednisone dose on the immune system probably also
explains why nothing happened -- but I had hoped it would do something
to persuade the bacteria it was time to leave.  Will get a test on my
next MD visit.

The course I gave myself was 600,000 i.u. over 33 days; I calculated
that this would be about  the same as from the sun exposure during a
month in the Caribbean.  And though I did not get the particular
'bang' for the buck I had hoped, I do have an overall sense of 'well
being' and feel more like my 'old' pre-sinusitis self; the symptoms
have not changed but I am handling them better.

I also have two free standing HEPA air filters in the house but so far
no allergy has been discovered (skin and RAST tests) -- anti
histamines old and new rapidly just clog me solid and make the mess
worse to move, as does Singular.  That is why I am so happy to have
found out about the Tea rinse, J&J shampoo etc. After seven years of
this nonsense, like Marla a cold that never left, anything reasonably
sane, however eccentric sounding, I am prepared to give at least a try
just to get the crud moving on out.

Michael
Susan - 10 Feb 2008 21:55 GMT
> This is interesting, and it makes sense that D3 would open things up--it's a
> secosteroid--related to prednisone. To be clear, are you dosing 10,000iu

I don't think the steroid action has anything to do with this effect, I
think it's the anti microbial and immunity enhancements, actually.
Steroids suppress my adrenals terribly, and D3 did, when I took the high
dose for too long.

I was using it three times per week, and endocrinologists recommend
50,000 once per week for those who are deficient.  But 10,000 once per
week has worked for others I've shared this with.

> once a week?
>
>  I know that the Food and Nutrition board set the UL of vit D extremely
> conservatively (some would argue paranoically) low at 2000iu.

Yes, but the vitamin D council of researchers disagrees strongly.  Most
people are deficient.

Susan
Andi - 13 Feb 2008 14:02 GMT
Could anyone of you point me to a reliable online supplier? Here, vit D3
is only available in very low doses (i.e. I would have to swallow
somewhere between 10 to 25 pills in order to reach 10,000) and I haven't
seen gel caps either.

Doing very well currently (with a very strict exercise regime, sauna and
enough rest - no irrigation, no sprays, no pills) but I would like this
infection to resolve completely.

Andi

P.S.: So the dosage would be 10,000 once a week for a month?

> I was using it three times per week, and endocrinologists recommend
> 50,000 once per week for those who are deficient.  But 10,000 once per
> week has worked for others I've shared this with.
Susan - 13 Feb 2008 14:32 GMT
> Could anyone of you point me to a reliable online supplier? Here, vit D3
> is only available in very low doses (i.e. I would have to swallow
> somewhere between 10 to 25 pills in order to reach 10,000) and I haven't
> seen gel caps either.

Carlson manufactures a 2000 iu gel cap; do a google product search and
see whose price is best.

> Doing very well currently (with a very strict exercise regime, sauna and
> enough rest - no irrigation, no sprays, no pills) but I would like this
> infection to resolve completely.

Have you also tried the black tea/saline irrigation?  It really helps
get stuff out.

> Andi
>
> P.S.: So the dosage would be 10,000 once a week for a month?

If you are deficient, it's 50,000 once a week until normal on serology.

If you're using it for sinus infection without deficiency, you should
feel intense drainage about one hour after taking it, as my sister and I
both did.  I took 10,000 iu a few times per week for two weeks, but if
your results are good enough, why take more than that?  If they aren't,
try it for a couple of weeks or so.  Unless you're testing your 25(OH)D,
I wouldn't megadose long term, frankly; it's a steroid hormone, and you
don't want to suppress, which is what happened to me after taking that
dose for too long.

Susan
Andi - 13 Feb 2008 16:26 GMT
> Carlson manufactures a 2000 iu gel cap; do a google product search and
> see whose price is best.

Considering the additional shipping costs and the fact that I don't need
120 caps, I'm reconsidering simply getting the pills here and swallowing
10 of those. Would that make a big difference? (I assume that the only
advantage of the caps would be the added oil/fats helping to absorb the
vitamin d3?).
I'd aim at 10,000 once a week for now.

> Have you also tried the black tea/saline irrigation?  It really helps
> get stuff out.

Well I only have problems with the right frontal sinus and I'm not
really clogged up by the mucus, it's simply the polyps sometimes
swelling up that bother me. Of course there is some drainage but only
very little. I might give it a try though.
I stopped saline irrigation last year and weaned myself off the steroid
spray as it was just a waste of time.
Susan - 13 Feb 2008 18:45 GMT
> Considering the additional shipping costs and the fact that I don't need
> 120 caps, I'm reconsidering simply getting the pills here and swallowing
> 10 of those. Would that make a big difference? (I assume that the only
> advantage of the caps would be the added oil/fats helping to absorb the
> vitamin d3?).
> I'd aim at 10,000 once a week for now.

I've read that the pills aren't well absorbed, but I have no citation
for that at the moment.  But if it works you'll know.  The drainage is
sudden and dramatic.

> Well I only have problems with the right frontal sinus and I'm not
> really clogged up by the mucus, it's simply the polyps sometimes
> swelling up that bother me. Of course there is some drainage but only
> very little. I might give it a try though.
> I stopped saline irrigation last year and weaned myself off the steroid
> spray as it was just a waste of time.

Good for you, getting off the steroid; it ultimately causes more of the
problem it's meant to treat, by shutting down endogenous steroid
production and prompting more release of proinflammatory corticotropin
releasing hormone.

My right frontal is the only one that shows mucosal thickening, too, on
C-T scan.

Susan
Murray Grossan - 14 Feb 2008 03:41 GMT
On 2/13/08 6:32 AM, in article 61gdc2F1uhgk8U1@mid.individual.net, "Susan"
<nevermind@nomail.com> wrote:

> x-no-archive: yes
>
[quoted text clipped - 29 lines]
>
> Susan
High doses of Vitamin D may have toxic effect. Many years ago Vit D was
popular as a cure for Arthritis until they found it caused serious kidney
stones. I have no information on D3 but any time you use an unproven dose as
to safety there may be a risk.
There are products  recommended  in high doses but until there is evidence
of safety caution is important.
Susan - 14 Feb 2008 14:38 GMT
> High doses of Vitamin D may have toxic effect. Many years ago Vit D was
> popular as a cure for Arthritis until they found it caused serious kidney
> stones. I have no information on D3 but any time you use an unproven dose as
> to safety there may be a risk.
> There are products  recommended  in high doses but until there is evidence
> of safety caution is important.

Murray, your information is hopelessly out of date, wrt vit D toxicity,
and it has a lot to do with promoting a crisis of vitamin D deficiency
that is epidemic.

Google up the vitamin D research council; they put the levels for safe
usage much higher than I've advised, time limited, here.

Susan
Murray Grossan - 14 Feb 2008 16:01 GMT
On 2/14/08 6:38 AM, in article 61j21sF1un0sdU1@mid.individual.net, "Susan"
<nevermind@nomail.com> wrote:

> x-no-archive: yes
>
[quoted text clipped - 13 lines]
>
> Susan
You are probably correct, as I said I am not familiar with this one. But I
have lived through many episodes where overdosage has been shown to be
harmful and brand new drugs have too. I try not to be the first kid on the
block.  One time colloidal silver was hailed as the cure all. Later we found
argyrosis.
Susan - 14 Feb 2008 16:26 GMT
> You are probably correct, as I said I am not familiar with this one. But I
> have lived through many episodes where overdosage has been shown to be
> harmful and brand new drugs have too. I try not to be the first kid on the
> block.  One time colloidal silver was hailed as the cure all. Later we found
> argyrosis.

We're not talking about overdosage, we're talking about a safe, non
toxic level for a limited time of something that's apparently cured me
and my sister, for example.  I have an awful URI of a week's duration
right now, and I've only irrigated twice; I have no signs or symptoms of
sinus infection at all.

Read the previous threads with citations on this group recently wrt Vit
D3, you may find the *real* sinus cure, though it would be bad for your
business interests:

About antimicrobial effect:

http://www.sciencenews.org/articles/20061111/bob9.asp

http://www.vitamindcouncil.com/newsletter/2006-june-july.shtml

About toxicity:

http://www.vitamindcouncil.com/vitaminDToxicity.shtml

Explore the research council site for fascinating information and
clinical applications.

All the Cushing's patients I know find that Vit D3 cures chronic sinus
infection (a constant in Cushing's), muscle and bone pain.

Susan
Susan - 14 Feb 2008 16:53 GMT
Check out publications by these folks:

http://www.vitamindcouncil.com/scientists.shtml

Susan
neil0502@yahoo.com - 14 Feb 2008 17:22 GMT
> x-no-archive: yes
>
> Check out publications by these folks:
>
> http://www.vitamindcouncil.com/scientists.shtml

There seem to be a bunch of relevant studies here:

 http://www.ajcn.org/cgi/content/full/85/1/6/T1
Susan - 14 Feb 2008 18:13 GMT
>>x-no-archive: yes
>>
[quoted text clipped - 5 lines]
>
>   http://www.ajcn.org/cgi/content/full/85/1/6/T1

Thanks for that page, Neil.

I don't want to come off as suggesting that D3 is a panacea, only that
it's safe, non toxic even in much higher than typical doses, most folks
are deficient and that my own experience, my sister's and that of
numerous other folks is that it cures even very longstanding chronic
sinus infections.

Thank goodness I never had unnecessary and typically non curative
surgery before discovering this effect.

If it works, you seem to get the intense drainage (at least my sister, I
and one other person I know did) shortly after taking it, an hour after,
for my sister and I.  I had the last remnants come out all at once the
next a.m. after irrigation.

Susan
neil0502@yahoo.com - 14 Feb 2008 19:32 GMT
> x-no-archive: yes
>
[quoted text clipped - 3 lines]
>
> Susan

Ah.  I missed this page.  I'll check it out when I can.

Meanwhile, I'm sticking with my healthy (< LD50) dose of skepticism
for just now.... ;-)
neil0502@yahoo.com - 14 Feb 2008 19:30 GMT
[snip]

> Read the previous threads with citations on this group recently wrt Vit
> D3, you may find the *real* sinus cure, though it would be bad for your
> business interests:

[snip]

> http://www.vitamindcouncil.com/vitaminDToxicity.shtml
>
[quoted text clipped - 5 lines]
>
> Susan

I don't have a whole lot of information on any of this, Susan,
honestly, but ... for one with a skeptical bent as yourself (which I
admire, BTW), what do YOU know about this "Vitamin D Council??"

All I can see is that it seems to be one guy -- John Jacob Cannell MD.

Is there $$ involved?? If so, then it flows from whom and to whom??
Is this info all peer-reviewed??

You see what I mean??  I really dunno' about D3 much at all, but ....
I'm not quite certain that this website because authoritative
reference material in my book quite yet.....

Neil
Susan - 14 Feb 2008 22:39 GMT
> I don't have a whole lot of information on any of this, Susan,
> honestly, but ... for one with a skeptical bent as yourself (which I
[quoted text clipped - 8 lines]
> I'm not quite certain that this website because authoritative
> reference material in my book quite yet.....

The researchers cited are highly credible.

Susan
neil0502@yahoo.com - 14 Feb 2008 23:12 GMT
> x-no-archive: yes
>
[quoted text clipped - 13 lines]
>
> The researchers cited are highly credible.

Hm.

Perhaps not surprisingly, that doesn't necessarily help ;-)
Susan - 15 Feb 2008 02:09 GMT
> Hm.
>
> Perhaps not surprisingly, that doesn't necessarily help ;-)

I know exactly what you mean.  But I meant it literally, not because of
credentials.

Besides, with my richly detailed anecdotal n of 3 or 4, what else do you
need?   ;-D

Susan
neil0502@yahoo.com - 15 Feb 2008 03:18 GMT
> x-no-archive: yes
>
[quoted text clipped - 8 lines]
> Besides, with my richly detailed anecdotal n of 3 or 4, what else do you
> need?   ;-D

Alright .... NOW I'm sold ;-)
Murray Grossan - 15 Feb 2008 04:41 GMT
On 2/14/08 11:30 AM, in article
4048e846-56e2-4783-88ff-cb08ed4af154@e6g2000prf.googlegroups.com,

> [snip]
>
[quoted text clipped - 28 lines]
>
> Neil
Again, don't get me wrong, I haven't investigated this as I am seldom the
first kid on the block.

But I have been there before. You should see the glowing insistent reports
on Laetril, cures EVERYTHING and the doctors are suppressing it because it
will hurt their business. Even polititions got involved pushing that one.

Take a look at Ear Stop.  A couple of drops and voila no more tinnitus! Look
at the glowing happy testimonials. See the happy, handsome faces.  And the
doctors suppress it so they can make money on the pain of others.

Want 101 other "cures" ?
Susan - 15 Feb 2008 15:35 GMT
> Again, don't get me wrong, I haven't investigated this as I am seldom the
> first kid on the block.
[quoted text clipped - 8 lines]
>
> Want 101 other "cures" ?

This is ironic, given the title of your book.

Somebody's irony meter is broken.

Vitamin D deficiency can be easily tested by checking 25(OH)D levels,
which must be above 32 at a minimum.  My level was normal, but taking a
very high dose of D short term has proven to be my sinus cure.

It's completely safe and easy to tell if it's worked or not.

Susan
Steven L. - 14 Feb 2008 16:11 GMT
> x-no-archive: yes
>
[quoted text clipped - 13 lines]
> Google up the vitamin D research council; they put the levels for safe
> usage much higher than I've advised, time limited, here.

According to the Mayo Clinic website:
The daily "upper limit" for vitamin D is 25 micrograms (1,000 IU) for
infants up to 12 months of age and 50 micrograms (2,000 IU) for
children, adults, pregnant, and lactating women due to toxicities that
can occur when taken in higher doses.

The "Vitamin D Council" is a group of ordinary folks who got themselves
a website.  Its leader is a political activist who has worked on a
variety of other trendy causes before glomming onto Vitamin D.  It is
not a recognized authority on nutrition.

Signature

Steven L.
Email:  sdlitvin@earthlinkNOSPAM.net
Remove the NOSPAM before replying to me.

Susan - 14 Feb 2008 16:51 GMT
> According to the Mayo Clinic website:
> The daily "upper limit" for vitamin D is 25 micrograms (1,000 IU) for
> infants up to 12 months of age and 50 micrograms (2,000 IU) for
> children, adults, pregnant, and lactating women due to toxicities that
> can occur when taken in higher doses.

That's old, outdated and not supported by the research, like most of the
Mayo health information on their web site.

> The "Vitamin D Council" is a group of ordinary folks who got themselves
> a website.  Its leader is a political activist who has worked on a
> variety of other trendy causes before glomming onto Vitamin D.  It is
> not a recognized authority on nutrition.

There are an awful lot of academic researchers at odds with your
statements. For good reason.

Most folks are deficient.  Endocrinologists treat deficiencies with
50,000 iu weekly til levels are over 32, preferably closer to 100 or the
middle of the range from 32-100.

After weeks of megadosing 10,000 iu Vit D3 and then stopping weeks ago,
my 2/1/08 level was 62.

And I haven't a hint of sinusitis or infection despite having had a
wicked URI all week and not irrigating daily.

For someone who routinely recommends invasive and often damaging surgery
for anyone with an infection, you sure are anti safe intervention.

Susan
Steven L. - 15 Feb 2008 13:53 GMT
>> According to the Mayo Clinic website:
>> The daily "upper limit" for vitamin D is 25 micrograms (1,000 IU) for
[quoted text clipped - 19 lines]
> After weeks of megadosing 10,000 iu Vit D3 and then stopping weeks ago,
> my 2/1/08 level was 62.

The scientific community has NEVER accepted the notion of megadose
vitamin therapy as curative for disease.  Never.  There are only a very
few exceptions to that rule, such as high-dose niacin for
cholesterol--but even that is known to risk serious side effects.  The
human body is designed to use a certain amount of nutrients.  Go way
beyond that and those nutrients are either excreted or build up causing
serious side effects.

I'm all for informed adult consumers using whatever they want to use on
their bodies.  Regardless of whether it's scientifically accepted or not.

But megadose vitamin therapy is NOT an accepted medical practice.  At
least not by mainstream medicine.  You ought to ask your endocrinologist
what double-blind controlled studies support the treatment that he has
prescribed for you.

The NIH office of Dietary Supplements agrees with the Mayo Clinic
recommendations.  There is a tight upper limit on how much Vitamin D may
be safely consumed, and you went way above that limit.  I'm glad you
personally suffered no ill effects.

http://ods.od.nih.gov/factsheets/vitamind.asp

BTW, while megadose vitamin therapy is considered "fringe medical
science," surgery remains the treatment of choice for chronic sinusitis.
 At least two different controlled follow-up studies have demonstrated
the lasting value of surgery.

Signature

Steven L.
Email:  sdlitvin@earthlinkNOSPAM.net
Remove the NOSPAM before replying to me.

blades49456 - 15 Feb 2008 15:01 GMT
Read the recent article on Vitamin D deficiency in the Scientific American.

Blades
Murray Grossan - 16 Feb 2008 03:52 GMT
On 2/15/08 5:53 AM, in article 13rb6bjsgpk572d@corp.supernews.com, "Steven
L." <sdlitvin@earthlink.net> wrote:

>>> According to the Mayo Clinic website:
>>> The daily "upper limit" for vitamin D is 25 micrograms (1,000 IU) for
[quoted text clipped - 47 lines]
>   At least two different controlled follow-up studies have demonstrated
> the lasting value of surgery.

For example doses of Pydridoxine over 100 mg twice a day is definitely
toxic. Yet I have seen that dose recommended!
Steven L. - 16 Feb 2008 14:25 GMT
> On 2/15/08 5:53 AM, in article 13rb6bjsgpk572d@corp.supernews.com, "Steven
> L." <sdlitvin@earthlink.net> wrote:
[quoted text clipped - 51 lines]
> For example doses of Pydridoxine over 100 mg twice a day is definitely
> toxic. Yet I have seen that dose recommended!

I once tried large doses of beta carotene.  My feet and hands ended up
looking like I had dipped them in yellow dye.  Fortunately, that effect
disappears when the intake of beta carotene stops.

Signature

Steven L.
Email:  sdlitvin@earthlinkNOSPAM.net
Remove the NOSPAM before replying to me.

Susan - 16 Feb 2008 14:47 GMT
> I once tried large doses of beta carotene.  My feet and hands ended up
> looking like I had dipped them in yellow dye.  Fortunately, that effect
> disappears when the intake of beta carotene stops.

That's not toxic, though, just silly looking.  It's common in babies fed
a lot of pureed carrots as a first food, too.

Susan
Susan - 16 Feb 2008 14:03 GMT
> The scientific community has NEVER accepted the notion of megadose
> vitamin therapy as curative for disease.  Never.

So what?  They have lousy record of getting things right, hence low fat
diets that lead to epidemics of diabetes, heart disease and kidney
failure, HRT for women that caused, didn't prevent the conditions they
claimed for decades, the acceptance of SIDS as heritable that led to
undetected homicides, and approval of lots of therapies and drugs that
treat surrogate end points while causing loss of quality of life and
even deaths.

> But megadose vitamin therapy is NOT an accepted medical practice.  At
> least not by mainstream medicine.  You ought to ask your endocrinologist
> what double-blind controlled studies support the treatment that he has
> prescribed for you.

You're completely wrong.  Megadosing of vitamin D up to 50,000 iu per
day is well accepted by endocrinology researchers, including my own,
chief of dept. and former NIH fellow endocrinologist.

> The NIH office of Dietary Supplements agrees with the Mayo Clinic
> recommendations.  There is a tight upper limit on how much Vitamin D may
[quoted text clipped - 7 lines]
>  At least two different controlled follow-up studies have demonstrated
> the lasting value of surgery.

You're still awfully ill for someone who's getting lasting benefits from
surgery.  So is Judy, who had access to the putative "best" in academic
medical settings.

High dose vitamin D is not toxic, it's not invasive, and if it doesn't
work, you at least won't have anatomical damage and a big surgical bill.

Susan

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