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Medical Forum / Diseases and Disorders / Sinusitis / February 2008postnasal drip and stomach upset
Did any of you ever hear of getting upset stomachs and loose stools from swallowing large amounts of infected and inflammatory post-nasal drip mucus? -Marla Comm > Did any of you ever hear of getting upset stomachs and loose stools > from swallowing large amounts of infected and inflammatory post-nasal > drip mucus? > -Marla Comm Yes, definitely. You can also get nausea and loose stools from the adrenal suppression by a lengthy infection that goes unchecked, if susceptible. Susan > Did any of you ever hear of getting upset stomachs and loose stools > from swallowing large amounts of infected and inflammatory post-nasal > drip mucus? Yep: "Symptoms of acute sinusitis are often confused with an upper respiratory infection and are often manifested as a continuation of upper respiratory symptoms. They can also include purulent or non-purulent nasal drainage (either rhinorrhea or post nasal drip), nasal blockage, the sensation of swelling in the nose or sinuses, ear symptoms, dizziness, difficulty concentrating, pain in the teeth, halitosis,pain on leaning over, fever, headache, cough, malaise, pharyngitis, etc. Gastrointestinal and even psychiatric symptoms are not unusual due to swallowing mucus." http://www.sinuses.com/md.htm  SignatureSteven L. Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. On Feb 1, 8:46 am, marlac...@hotmail.com wrote: > Did any of you ever hear of getting upset stomachs and loose stools > from swallowing large amounts of infected and inflammatory post-nasal > drip mucus? > -Marla Comm Yes, most definately! After my 1rst sinus surgery I got a horrible, nasty infection and developed an abcess. I was soooo sick. I lost 15lbs in 2 wks as I was so nauseated from the nasty drainage. I did throw up several times and also had dry heaves. Jenise > On Feb 1, 8:46 am, marlac...@hotmail.com wrote: > [quoted text clipped - 9 lines] > I did throw up several times and also had dry heaves. > Jenise Marlac, YES YES & YES! Finally someone asks this question! I was just asking this same thing to someone who works in the sinusitis field (not a Doc)and talks to patients daily to see if he had ever heard of this with all of the sinus sufferers he talks with. (Not really, was the answer but he felt that for there defiantly could be a relationship) I thought I was crazy for even thinking that there was a relationship but I have the same symptoms, just add excessive gas to your list (to the joy of my wife, who puts up with it) I'm so relieved to know that I'm not teh only one with the nausea and bowel problems. Sergei91 > Did any of you ever hear of getting upset stomachs and loose stools > from swallowing large amounts of infected and inflammatory post-nasal > drip mucus? > -Marla Comm It have eosinophilic non allergic rhinitis Rinse my sinuses twice each day with prescription drug About twice each week I use a steriod rinse to stop pollups from forming I live on Sudafed About 4 hours ignoring my sinuses will make me quite sick to my stomach and shortly after that comes the rest of the problems. Sometimes the changing weather or my schedule seems to be all it takes. The effect is absolutely real I am sorry to say. > <marlac...@hotmail.com> wrote in message > [quoted text clipped - 4 lines] > > drip mucus? > > -Marla Comm Rhinosinusitis derived Staphylococcal enterotoxin B possibly associates with pathogenesis of ulcerative colitis. Yang PC, Liu T, Wang BQ, Zhang TY, An ZY, Zheng PY, Tian DF. Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada. yangp@mcmaster.ca BACKGROUND: During clinical practice, we noticed that some patients with both ulcerative colitis (UC) and chronic rhinosinusitis (CRS) showed amelioration of UC after treatment of CRS. This study was designed to identify a possible association between CRS and UC. METHODS: Thirty-two patients with both CRS and UC received treatment with functional endoscopic sinus surgery (FESS) for CRS. Clinical symptom scores for CRS and UC, as well as serum levels of anti- Staphylococcal enterotoxin B (SEB) were evaluated at week 0 and week 12. Sinus wash fluid SEB content was measured with enzyme-linked immunosorbent assay (ELISA). The surgically removed tissues were cultured to identify growth of Staphylococcus. aureus (S. aureus). Immunohistochemistry was employed to identify anti-SEB positive cells in the colonic mucosa. Colonic biopsies were obtained and incubated with SEB. Mast cell activation in the colonic mucosa in response to incubation with SEB was observed with electron microscopy and immunoassay. RESULTS: The clinical symptom scores of CRS and UC severe scores (UCSS) were significantly reduced in the UC-CRS patients after FESS. The number of cultured S. aureus colonies from the surgically removed sinus mucosa significantly correlated with the decrease in UCSS. High levels of SEB were detected in the sinus wash fluids of the patients with UC-CRS. Histamine and tryptase release was significantly higher in the culture supernate in the patients with UC-CRS than the patients with UC-only and normal controls. Anti-SEB positive cells were located in the colonic mucosa. CONCLUSION: The pathogenesis of UC in some patients may be associated with their pre-existing CRS by a mechanism of swallowing sinusitis-derived SEB. We speculate that SEB initiates inappropriate immune reactions and inflammation in the colonic mucosa that further progresses to UC. PMID: 16144553 [PubMed - indexed for MEDLINE] > > <marlac...@hotmail.com> wrote in message > [quoted text clipped - 4 lines] > > > drip mucus? > > > -Marla Comm "Staphylococcal Enterotoxins The SEs, SEA through SEI except SEF, are produced by various coagulase- producing staphylococci. Although known for many years as the cause of SFP, they have only recently been shown to be superantigenic, and in particular SEB and SEC have been implicated in nonmenstrual TSS. All SEs thus far characterized have the immunomodulatory properties of superantigens, and several have been demonstrated to be lethal in the rabbit model of TSS. Molecular studies of the SEs have shown that superantigenicity and the capacity for causing SFP are determined by separate parts of the protein (2, 67). Several reviews of SEs are available, and other sections of this review provide background on toxin genetics and TSS pathogenesis. All toxins thus far identified share a number of important properties (10, 12, 24, 26), including (i) an ability to cause emesis and gastroenteritis in a primate model, (ii) superantigenicity, (iii) intermediate resistance to heat and pepsin digestion, and (iv) tertiary structural similarity (where known) including an intramolecular disulfide bond. " Note point (iii) intermediate resistance to ... pepsin digestion, from:- Exotoxins of Staphylococcus aureus Martin M. Dinges, Paul M. Orwin, and Patrick M. Schlievert* Department of Microbiology, University of Minnesota School of Medicine, Minneapolis, Minnesota 55455 Clin Microbiol Rev. 2000 January; 13(1): 16-34. Copyright (c) 2000, American Society for Microbiology Full text at:- http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=10627489 |
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