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Medical Forum / Diseases and Disorders / Sinusitis / January 2008Bactrim... Reactions?
Last December I developed a rather severe sinusitis flair-up. ...I went to the Dr., and he prescribed the usual 3 weeks of levaquin. It didn't work all that great, this time, and two days after my prescription ran out, I developed a severe sore throat, and my sinustis came back about 3 times worse. ...I went to the Dr. and he prescribed 2 weeks of (bactrim) Sulfatrim 400-80mg -- 2 tablets, twice a day. I have never had any noticeable reactions to any antibiotics before, but a few days ago, while I was brushing my teeth -- and didn't have my shirt on, I noticed a pile of little red marks on my arms and shoulders. On close examination, it looks almost like I had been clearing out some spruce trees, without my shirt on. ...It's like a rash, but up close it looks almost like a broken vessel... Like what you see on old people's noses. There is no pain or itching. I cut my prescription in half last night, and before taking another pill, I'm going to visit the pharmacist. Has anyone got any ideas what this is? ...And has it happened to anyone else? Incidentally, the pills do make you light sensitive, but it isn't exactly sun bathing weather right now, up in Canada here. ..Jon On Jan 18, 8:07 am, Johnny1...@webtv.net wrote: > Last December I developed a rather severe sinusitis flair-up. ...I went > to the Dr., and he prescribed the usual 3 weeks of levaquin. It didn't [quoted text clipped - 19 lines] > isn't exactly sun bathing weather right now, up in Canada here. > ..Jon Ummm. Hate to go here, but ... you asked. Maybe seven/eight years ago, I was using Restasis (ophthalmic cyclosporine) to treat dry eye. Restasis is an immunosuppressant. The theory is that much dry eye is an inflammatory condition. During that time, I -- of course -- got a wicked sinus infection. I was given Bactrim, a drug I had taken numerous times before, without incident. Maybe five days into it, I experienced a "fixed drug eruption." My weenie exploded. Blisters, papules, pustules, zonules, ampules, joules, and every other "-ules" word you could think of. It was NOT my finest hour/week. I'm very careful to mention a Bactrim allergy these days. Turns out that Bactrim IS a common reaction drug, including Stevens- Johnson Syndrome, and that Ye Olde Weenie IS a common reaction site. Who knew? When asked about drug allergies, no intake nurse is ever content with "fixed drug eruption," so ... when pressed ... I offer that my "weenie exploded." The room gets very quiet, very quickly. And I just grin like a cheshire cat. >My weenie exploded. Blisters, papules, > pustules, zonules, ampules, joules, and every > other "-ules" word you could think of. Good Lord !! 'Scuse me, while I whip this out..... Well... Everything is still OK down there, thank God. I have never had any reaction to taking to any antibotics before, but I talked to the Pharmacist (an hour ago), and she said she wanted to check out my weenie ... Ahh... Just kidding (I should be so lucky) ;-) ..But, she did say to mention this reaction to the Dr., and to carry on with my prescription (4 more days), providing it didn't get any worse. ..Jon. On Jan 18, 12:04 pm, Johnny1...@webtv.net wrote: > neil0...@yahoo.com wrote: > [quoted text clipped - 3 lines] > > Good Lord !! 'Scuse me, while I whip this out..... TYVM for the _Blazing Saddles_ reference. What a great flick that was..... ;-) Glad the Unit's still good..... I used to prescribe a lot of bactrim at one time, cheap, on forumulary, and saw tons of rashes and reactions in both adults and children. Personally, I got a nasty rash on it after using it several times: big, fixed welts on my abdomen. The fixed drug reaction that Neil had,I've seen it with a patient whom I put on doxycyline, He didn't explode, but it was purple... Recently, because of MRSA, we've gone back to using bactrim, and Ive gone back to seeing drug reactions. A recent patient with MRSA came back with a total body red red rash, high fever, hugh nodes. I've seen Stevens-Johnson reaction with it-- the bull's eye rash that can become a systemic issue and involve mucosa. So, I'd be very suspicious of bactrim, and I'd have the doctor check it before continuing the course. The recent patient with the total body rash and fever was really sick... Judy On Jan 18, 3:04 pm, Johnny1...@webtv.net wrote: > neil0...@yahoo.com wrote: > [quoted text clipped - 12 lines] > with my prescription (4 more days), providing it didn't get any worse. > ..Jon. >So, I'd be very suspicious of bactrim, and I'd > have the doctor check it before continuing the > course. > > The recent patient with the total body rash > and fever was really sick... Well, it did seem to work quite well at getting my sinusitis under control... Nevertheless, having a purple penis eater lurking about is not my idea of a cure... I'm seeing my Dr. on Monday, so I think I'll have him cross this particular drug off the list... ...But damn.. It is cheap. Only cost me 16 bucks for 56 tablets. Thanks for the information... Jon > Last December I developed a rather severe sinusitis flair-up. ...I went > to the Dr., and he prescribed the usual 3 weeks of levaquin. It didn't [quoted text clipped - 16 lines] > > Has anyone got any ideas what this is? Sounds like an allergic reaction to me. Does it look like this? http://en.wikipedia.org/wiki/Image:Erythema_multiforme.jpg Or does it look like this? http://tinyurl.com/39j2qo  SignatureSteven L. Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. sdlitvin@earthlink.net (Steven L.) wrote: >Sounds like an allergic reaction to me. > [quoted text clipped - 6 lines] > >http://tinyurl.com/39j2qo It's closer to the 2nd. picture, but not even a tenth as severe as that poor guy has it. I don't have raised welts, but rather a multitude of little red dots, like I was working around a thorn bush, or something. ..Jon >> Sounds like an allergic reaction to me. >> [quoted text clipped - 11 lines] > little red dots, like I was working around a thorn bush, or something. > ..Jon Well, that 2nd picture is a picture of an allergic drug reaction. So it looks very much like that is what you have. Take some Benadryl (diphenhydramine), and it should help knock down that reaction. SignatureSteven L. Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. It's always best if the prescribing person can actually see the rash: what you're describing sound like petechia: little bruises. (Not a classic drug eruption.) Drug rashes can take a number of different forms: hives, morbiliform rashes--start as red dots and become a wide spread rash that is both flat and raised, Stevens-Johnson, erythema multiforma. So, when in doubt, with a rash, it's best to have someone actually look at it. What's tough is that viruses can cause rashes too--more often in kids. So, no diagnosis over the internet. Time to have someone take a peak, in my opinion. Although drug reaction makes a lot of sense. Yeah, bactrim is cheap, and works, but that sulfa tends to be a bad actor when it comes to skin eruptions. Judy > Johnny1...@webtv.net wrote: > >> Sounds like an allergic reaction to me. [quoted text clipped - 23 lines] > Email: sdlit...@earthlinkNOSPAM.net > Remove the NOSPAM before replying to me. The second picture is a classic morbiliform drug rash. (Sorry I hadn't looked yet.) FYI Judy > It's always best if the prescribing person can actually see the rash: > what you're describing sound like petechia: little bruises. (Not a [quoted text clipped - 39 lines] > > Email: sdlit...@earthlinkNOSPAM.net > > Remove the NOSPAM before replying to me. > It's always best if the prescribing person can actually see the rash: > what you're describing sound like petechia: little bruises. (Not a [quoted text clipped - 4 lines] > So, when in doubt, with a rash, it's best to have someone actually > look at it. I tried that once for a maculopapular rash I got from Ceftin, but the physician didn't know as much about rashes as either you or I do. He actually thought they were insect bites! SignatureSteven L. Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. Sad but true. After years of ceftin, I started to developed isolated hives on it. My allergist made a homemade serum and skin tested me-- negative--and has been willing to give it an oral challenge, but I never did it. I heard a great lecture on drug reactions from a woman from Mass General, about 5-6 years ago. She was amazing, and knew so much. My daughter gets bronchospasm from motrin/aspirin--and the nurses at Harvard Pilgrim told us not to worry, while the allergist told her to avoid it, and this woman--I want to say Marianna something--was the first person to explain the pathogenesis--a build up of leukotrienes, and how the COX-2 inhibitors could be used safely. Until it was yanked off the market, she used vioxx. Also, if you take singulair, you can block the reaction. She gave a great discussion about the multiple pathways for drug reactions/eruptions. There used to be a great group based from Partners, who gave this intense allergy seminar, but--I'm not making this up--the esteemed leader was convicted of killing his wife in a park outside of Boston, and that was the end of the lectures. Weird. Judy > > It's always best if the prescribing person can actually see the rash: > > what you're describing sound like petechia: little bruises. (Not a [quoted text clipped - 13 lines] > Email: sdlit...@earthlinkNOSPAM.net > Remove the NOSPAM before replying to me. |
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