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Medical Forum / Diseases and Disorders / Sinusitis / July 2007amoxicillin dosage
I have some 250 mg Amoxicillin tablets. I know some people think that another antibiotic is better for sinusitis but this is what I have for now. Can anyone tell me what the dosage program would be for these? How many a day? Thank you! > I have some 250 mg Amoxicillin tablets. I know some people think that > another antibiotic is better for sinusitis but this is what I have for now. > Can anyone tell me what the dosage program would be for these? How many a > day? Where'd you get them, how many do you have, and how long could you take them? Chances are that dose won't even piss off an infection, much less kill it, but it might make it less likely to respond to somthing stringer, like Augmentin XR. Susan >> I have some 250 mg Amoxicillin tablets. I know some people think that >> another antibiotic is better for sinusitis but this is what I have for [quoted text clipped - 3 lines] > Where'd you get them, how many do you have, and how long could you take > them? ~~~~~~ I have 30 and could take them to the end.... just don't know how many a day I should take.. > Chances are that dose won't even piss off an infection, much less kill it, > but it might make it less likely to respond to somthing stringer, like > Augmentin XR > ~~~~~~ I have 30 and could take them to the end.... just don't know how > many a day I should take.. So you have a low dose of amoxicillin and only enough to take that for 10 days? That's a recipe for breeding resistant bacteria. If you think you have a sinus infection that needs treating, see someone who can prescribe something that won't leave you worse off. 250mg is half the normal adult 3X per day dose, IIRC. Susan > So you have a low dose of amoxicillin and only enough to take that for 10 > days? [quoted text clipped - 4 lines] > > 250mg is half the normal adult 3X per day dose, IIRC. ~~~~~~~~~ what if I take 500mg 3X a day, for 5 days. My problem is that I discovered last week that I was taken off my husbands ins last Nov '06. I didn't know this and thought I was covered. We just recently filed for divorce. I'm trying to reinstate it because I was never notified and never received any Cobra packet or information. Anyway, bottom line is I don't have insurance right this minute. To tell you the truth, I don't know if it's infected or not. I've been able to tell before by the greenish color, but this time, my nose is not plugged and I'm not getting any post-nasal drip, but my ears are ringing and left ear has that ticking sound, and when I hold my nose and try to blow, I can tell there's some plugged up/blocked areas by the popping in my ears. Althought the left side doesn't pop at all. Must be way back in my inner or middle ear? I get the burning eyes sometimes, and sometimes get a little pain in my ear. I've flushed my nose with a squeezer thing normally for ear wax... warm salt water... and did get some blood. It's been like this for a while and I just hate the thought of the bacteria in there, so close to my brain and eyes. I know. You're gonna tell me I need to see a doc. > > So you have a low dose of amoxicillin and only enough to take that for 10 > > days? [quoted text clipped - 22 lines] > the bacteria in there, so close to my brain and eyes. I know. You're gonna > tell me I need to see a doc. Camron: Amoxicillian is useful to fight free floating bacteria. it would keep you from getting a blood stream infection, but can not disrupt an intact biofilm. Seeing a doctor is the right thing to do, if only to check it off the list. If you have a good family physician you might find him/her more concerned and useful than an ENT. You can probably get some temporary relief by making dilute sinus wash by adding 1 oz of 3% peroxide to 8oz of warm salt water and using it all at least once a day. and using Vitiman C and pepcid or Zantac as throat lozenges, I have also had some luck with swabbing my nose with tolfanate athlete's foot cream. I know it sounds weird, but it brings down the green things at a comparatively tiny cost. You will need to prepare to spit them and it out when it slides down the back of your throat. I have had good results with Zagarese Licorice used as a lozenge at night. then sniff, sniff, blow, blow. If you can get your family doc to call in a script Biaxin is clithromycian and can be had in generic form for a reasonable cost. > Camron: > [quoted text clipped - 21 lines] > If you can get your family doc to call in a script Biaxin is > clithromycian and can be had in generic form for a reasonable cost. ~~~~~ thanks. I had heard about using peroxide but wasn't sure of the proportions... I'll try that. I ordered some of the Zagarese and I was sceptical, but when I put about 4 of them in my mouth, I can actually start to feel a bit of something starting to come down my throat but never seems to come all the way. Damn stuff is like a rubberband and seems to spring back up! Been taking Vit C chewables too, and just letting them dissolve slowly. Sounds gross, but I used to have a friend who was real good at hacking it out in the shower but I'm not too good at that. Oh well, I'll try the peroxide and continue with the other stuff. :) >> So you have a low dose of amoxicillin and only enough to take that for 10 >> days? [quoted text clipped - 6 lines] >> > ~~~~~~~~~ what if I take 500mg 3X a day, for 5 days. No, that probably won't clear the infection in time and again you'll breed a resistant infection. Especially given your history of past infections. No matter how you juggle it, this won't cover it. > My problem is that I > discovered last week that I was taken off my husbands ins last Nov '06. I > didn't know this and thought I was covered. We just recently filed for > divorce. I'm trying to reinstate it because I was never notified and never > received any Cobra packet or information. Anyway, bottom line is I don't > have insurance right this minute. I understand the problem. However, many physicians have free samples of various antibiotics in their office. If you tell a doctor that you don't have health insurance right now and you're going thru a divorce, s/he is likely to offer you some free samples of a powerful antibiotic that might tide you over past this infection. You will have to pay for the doctor's visit though.  SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. > >> So you have a low dose of amoxicillin and only enough to take that for 10 > >> days? [quoted text clipped - 30 lines] > Email: sdlit...@earthlinkNOSPAM.net > Remove the NOSPAM before replying to me. Cameron: Try the licorice and the vitamin C together while lying on the bad side. The get up and Sniff, sniff, sniff, spit. The thing that you are discribing like it is far back at you adenoids. at that location it is a lot easier to get it out the back way. Cavet; if the licorice gets it, it will feel as if that spot has been subjected to tannin and it will kind of ache for a while. Advil will help. Using he stuff i have discribed, I have been able to get rid of most of it but not all. There is always enough left to eventually come back no matter what series of treatments and prescription and non prescription drugs I have used. But I have never been given azrithromycian at all or 3 weeks of a macrolide and intraconazole with a statin or bisphosphonate. And there is something else called Mucomist I have heard refered to along with it that the hospital lab techs use on themselves. I hope you have a friendly concerned doc that will give you the right stuff. I would just agree that the usual dose of amoxicillin: which can be dosed twice a day, is about 875 mg twice a day or 500 mg three times a day. The insurance thing sounds like you need a lawyer to sort out. When I see a "self-pay" patient, I tend to code the lowest visit code possible, and give out samples. I used to work at the community health center, and they charged a slidiing scale, based on some income formula. There are all those "Minute Clinics" now in the big box stores, and they probably don't sample (they're financed through CVS/Walmart) but they don't charge much per visit.(Amoxicillin should be a $4 drug at Walmart.) Primary care doctors are very distressed about them. But, we close at 5, and waiting in in ER stinks, and there are a few good free standing urgent visits around, but some insurances charge a huge co-pay ($100) to use them. When I called Blue Cross to complain, they said it was designed to stop ER abuse. Like you time you illness, when your doctor's ofice is open banker's hours... Good luck. There is some controversy about the peroxide rinses, as peroxide is toxic to mucosa. So, if it hurts at all, I'd stop it. Personally, I weakly acidify my saline rinses, to discourage pseudomonas, with about a 1/2 tsp of white vinegar/quart. Judy > > >> So you have a low dose of amoxicillin and only enough to take that for 10 > > >> days? [quoted text clipped - 54 lines] > I hope you have a friendly concerned doc that will give you the right > stuff. > I would just agree that the usual dose of amoxicillin: which can be > dosed twice a day, is about 875 mg twice a day or 500 mg three times a [quoted text clipped - 11 lines] > they don't charge much per visit.(Amoxicillin should be a $4 drug at > Walmart.) The usual first-line antibiotic for sinusitis is Augmentin (amox + clavalanate), rather than straight amox. Augmentin is now available generically too. So is Ceftin, a comparable cephalosporin. Macrolides (Biaxin, Zithromax) have an Achilles' heel these days: Staph aureus has become resistant. So with macrolides you have to hope that your infection isn't staph. Hey Judy, I still have 14 days worth of Ketek in my drawer--it was a prescription I never used because my acute infection resolved spontaneously that time. What do you suggest I do with it? :-) SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. Steven, We just tossed the samples we had in the sample closet. That stuff is so dangerous--now it's in the landfill somewhere... They never deal with what to do with recalled or restricted drugs: but I did know people who hoarded their vioxx.... Judy Steven, I agree that augmentin and ceftin are better drugs, but the occasional person who is antibiotic naive will do okay on amoxicillin, especially if the dose is high enough. For kids, we used to dose them at 40mg/kg, but with resistance it got increased to 80mg/kg. Intermediate resistant bugs will respond to higher dose amoxicllin: hence the creation of augmentin XR (2 gm of amoxiclllin/day plus clavuinate.) Again, with the macrolides, their valiue is mostly in anti- inflammatory and preventing adhesion: not strictly antimicrobial use. I can personally attest to that usage. For MRSA, the drugs of choice are bactrim, doxcycline and clindamycin (which is can induce rapid resistance.) We're all using bactrim again, and seeing those sulfa skin reactions again... There was a study of MRSA in community ER's and even if a drug that shouldn't work--such as keflex was used, patients got better as long as their abscesses were drained. Judy > > I would just agree that the usual dose of amoxicillin: which can be > > dosed twice a day, is about 875 mg twice a day or 500 mg three times a [quoted text clipped - 29 lines] > Email: sdlit...@earthlinkNOSPAM.net > Remove the NOSPAM before replying to me. > Steven, > We just tossed the samples we had in the sample closet. That stuff [quoted text clipped - 53 lines] > > Email: sdlit...@earthlinkNOSPAM.net > > Remove the NOSPAM before replying to me. On a non-antibotic note entirely; Try holding Dannon's DanActive Immunity in your mouth while lying on your side for about an hour or so. The l.casi immunitas fights the goo. > I would just agree that the usual dose of amoxicillin: which can be > dosed twice a day, is about 875 mg twice a day or 500 mg three times a [quoted text clipped - 82 lines] > > I hope you have a friendly concerned doc that will give you the right > > stuff. judy, i'm wondering if you can explain the vinegar/pseudomonas component re: irrigation? what is the ratio (of the irrigation solution that you use)? ellen Ellen, Pseudomonas doesn't tolerate acidic environments--but loves dark, wet spaces, which is why it is the primary organism for swimmer's ear, and one of the treatments is VoSol--essentially acetic acid (white vinegar.) I had a pseudomonas bone infection (osteomyelitis) after a surgery, and did a lot of article searching and my ENT recommended acidifying my rinses (and somewhere I found a reference to agree with that.) The usual recommendation is a pinch of baking soda whick is alkaline--recommended for many irrigation solutions. But after my infection, I wanted to rinse with a more acidic wash. I found that too much vinegar was really irritating, so I used to put a tsp in a quart of boiled water with 4 tsp of kosher salt, and recently I realized that my nose was irritated a lot, so I cut back to about a 1/2 tsp of vinegar per quart. The tap water here is acidic-- one of my kids once did a science experiement and we figured it out. I don't remember the pH. So, to discourage pseudomonas, I irrigate with acidified rinse. White vinegar is a nice cleaner for the NeilMed bottle and any tubing that might harbor water loving bacteria. So is bleach, but the vinegar is easier to tolerate if some remains in the device when you irrigate. Judy > > I would just agree that the usual dose of amoxicillin: which can be > > dosed twice a day, is about 875 mg twice a day or 500 mg three times a [quoted text clipped - 89 lines] > > ellen > Ellen, > Pseudomonas doesn't tolerate acidic environments--but loves dark, wet [quoted text clipped - 111 lines] > > > ellen Wouldn't the quantity of salt per quart be a 1/2 teaspoon for an isotonic solution? Different people find different concentrations of salt useful and comfortable. The reason that Judy mentions Kosher salt is because lots of people find the iodine in regular table salt stings. Personally I find that anything, including an isotonic salt solution is going to sting when your sinuses are really raw, and if and when you are able to get the goo mat, (biofilm, psudomemebrane, etc. etc. )to peal off, it hurts like a mother. I had an episode where I was in a hotel room in a strange city, sinuses draining yellow goo, feeling every breath like a blowtorch between the eyes. I tied threads to little finger size peices of cotten, saturated them with peroxide and packed them up in my nose where it hurt. The next morning the goo leaking down the front had stopped and the ulcer that was hurting so badly when air went by had evidently healed over night. I thought I had won, and I had, one square centimeter down, 600 sq centimeters to go. So the peroxide is not so bad, just difficult to use sometimes. Elizabeth: I prefer a hypertonic solution: kosher salt and sea salt are much larger granules than table salt, so I find that I use twice the amount. I've used the 1 tsp kosher salt/cup for years, and it doesn't sting--for me. Jud > > Ellen, > > Pseudomonas doesn't tolerate acidic environments--but loves dark, wet [quoted text clipped - 134 lines] > centimeters to go. > So the peroxide is not so bad, just difficult to use sometimes. > Elizabeth: I prefer a hypertonic solution: kosher salt and sea salt > are much larger granules than table salt, so I find that I use twice [quoted text clipped - 140 lines] > > centimeters to go. > > So the peroxide is not so bad, just difficult to use sometimes. Judy: Did you notice the artical I posted on the mode of action of Azithromycin? Being based around lactones,not anything that looks like an NSAID or a fatty acid like a steroid, I have long suspected that the macrolides were primarily signal jammers, and their anti-inflammatory effects are due to ramping down the pro-inflammatory factors of the bacteria. Amoxicillan has no such action, it is a straight metabolic poison to dividing cells, and since once bacteria have settled down in a biofilm they produce things like beta amyloid, and coagulase, to stick them the surface and protect them, and hyaluronidase, staphlokaniase, hemolysins, and protease to allow them to establish a wound and chow down on the blood flowing out of the ulcer, but they divide infrequently, and some of the cells stand by and devide don't divide at all for 3 weeks at at time. The amox does not bother them much, as shown by it's complete ineffectiveness in the Calgary trials. I think that amox may be usefull proactively to kill the bacteria while they are still free floating before the biofilm is established (that application that you get hammered for is where it actually shines), but the biofilm devise tests show that once the biofilm is established it is extremely unlikely that amox will be more than a temporary inconvenience to it. Elizabeth |
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