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Medical Forum / Diseases and Disorders / Sinusitis / May 2007

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Candida albicans Biofilms Produce Antifungal-Tolerant Persister Cells

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truehawk - 16 May 2007 05:49 GMT
http://aac.asm.org/cgi/content/full/50/11/3839?maxtoshow=&HITS=10&hits=10&RESULT
FORMAT=&fulltext=biofilms&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT


But there is a way, if Cryptococcus neoformans is typical:

http://aac.asm.org/cgi/content/full/50/6/2132?maxtoshow=&HITS=10&hits=10&RESULTF
ORMAT=&fulltext=biofilms&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT


Note that the fungi in biofilm is pretty much immune to gamma rays.
It takes a -riggin Alpha emitter to can it.

I have considered coating the biofilm with iron nanoparticals and then
activating them with an MRI.
It would cook the bugs, but control would be tricky.
Kofi - 19 May 2007 07:20 GMT
Butyrate sensitizes candida albicans to azoles and other related
antifungals [PMID 12384361].

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