Ciclesonide? (and other new rhinitis meds)

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MS - 09 Mar 2007 21:23 GMT

Ciclesonide is a new inhaled steroid that is supposed to be very effective,
with less systemic absorption than the others. It was approved by the FDA
last year, including a nasal spray version to have the brand name "Omnaris".

Does anyone know when this will actually be on the market in the US? (I
think it is already available in Europe.)

Also, there is supposed to be a new antihistamine nasal spray to come on the
market (to add to the only current one, Astelin), using the same
antihistamine that is in the eye drops Patanol. Anyone know when that will
be available?

Also, does anyone have news on what happened /will happen to Nasacort HFA?
It is a new aerosol version (CFC-free) of Nasacort. Approved by the FDA
almost three years ago, in April 2004, but AFAIK never yet came to market.
What happened to it?

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Andries - 11 Mar 2007 19:16 GMT

Here in The Netherlands Ciclesonide is only released as Asthma medicin. It
must be inhaled. It is not a medicine for Sinusitis.

Andries

> Ciclesonide is a new inhaled steroid that is supposed to be very
> effective, with less systemic absorption than the others. It was approved
[quoted text clipped - 13 lines]
> almost three years ago, in April 2004, but AFAIK never yet came to market.
> What happened to it?

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MS - 12 Mar 2007 01:21 GMT

In the US it is supposed to become available in both forms, an asthma
inhaler and a nasal spray. You are ahead with the asthma inhaler. Perhaps
the nasal spray will come out there the same time it does here.

> Here in The Netherlands Ciclesonide is only released as Asthma medicin. It
> must be inhaled. It is not a medicine for Sinusitis.
[quoted text clipped - 18 lines]
>> FDA almost three years ago, in April 2004, but AFAIK never yet came to
>> market. What happened to it?

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BigBenBiker - 15 Mar 2007 15:37 GMT

>In the US it is supposed to become available in both forms, an asthma
>inhaler and a nasal spray. You are ahead with the asthma inhaler. Perhaps
>the nasal spray will come out there the same time it does here.

So, does it basically work as an anti-histamic?

Regards,
jbr

Ride your 2 wheels, but in order to ride them yet another day!
bbb

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MS - 17 Mar 2007 21:04 GMT

No, a steroid nasal spray (Flonase, Nasonex, Rhinocort, etc.) is not an
antihistamine.

There is one antihistamine nasal spray on the market (Astelin), and as I
wrote, there seems to be another in development, not yet available. But
that's not the ciclesonide, which is a steroid inhaler and nasal spray,
neither available yet in the US.

>>In the US it is supposed to become available in both forms, an asthma
>>inhaler and a nasal spray. You are ahead with the asthma inhaler. Perhaps
[quoted text clipped - 4 lines]
> Regards,
> jbr

No>

> Ride your 2 wheels, but in order to ride them yet another day!
> bbb

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