It works pretty well.
Serrapeptase is the enzyme made by Serra bacteria in the gut of
silkworms to slices up amyloid proteins. Silk is an amyloid protein,
which means that iodine turns it black just as it does starch or
'amyla".
The curli and pili of pilliated bacteria are formed of amyloid protein
and those bacteria make soluible amyloid oglimeres and then catalyse
amyloid bungees that hold the bacteria to each other out of solution.

Taking doses equivilent to that given to rabbits in the Japanese
experiments did greatly reduce the viscosity of the goo, but it made
my trusty feet hurt badly in the arches and side of my heels.  Don't
know it that is bacause it was sliceing up Amyloid P that the body
makes and uses in ligimants, or because their was some bug there that
gave off toxin while dying.  If the latter, it could be different for
different people.
Lower doses are supposed to help arthritis, so it is a mystery.