Nasomex???

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MZB - 25 Oct 2006 00:01 GMT

I've had this damn sinus infection since 9/1

Doc gave me nasonex. Said it would help if it is allergy-related.

Any dangers in taking this spray, twice a day??

Mel

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Susan - 25 Oct 2006 01:28 GMT

> I've had this damn sinus infection since 9/1
>
> Doc gave me nasonex. Said it would help if it is allergy-related.
>
> Any dangers in taking this spray, twice a day??

Not if you do it for no more than two or three weeks before stopping it
for a week or two.

Inhaled steroids cause adrenal suppression, and you end up with a
problem worse than you started with, along with immune suppression in a
part of your body that's trying to fight an infection.

Susan

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rick@spamgmail.com - 25 Oct 2006 02:41 GMT

>x-no-archive: yes
>
[quoted text clipped - 12 lines]
>
>Susan

On the advice of doctors, I use Nasonex 2 sprays, once a day. I
honestly can't tell you whether it helps or harms. I guess I could
stop for a couple of weeks to find out, then I figure I should stop
with Astelin as well.

Susan, if they are bad for you, why are they prescribed so readily?
Could it be that they are not good for you, but that they help a large
% of people? That's really not a rhetorical question. I don't know
the answer, just asking.

Rick

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Susan - 25 Oct 2006 14:06 GMT

> Susan, if they are bad for you, why are they prescribed so readily?

Ignorance and neglect on the part of the docs rx'ing them. They rely too
heavily on false assurances from pharaceutical reps instead of reading
the available research on each drug they prescribe.

> Could it be that they are not good for you, but that they help a large
> % of people? That's really not a rhetorical question. I don't know
> the answer, just asking.

I've no doubt that they can be a useful tool for short term management
of an acute condition, with proper instructions and vacations without
use of steroids.

Susan

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ilaboo - 26 Oct 2006 13:44 GMT

studies have shown that there is a very minumal absorbsion of nasonex

if is a very good treatment as it cuts down on naasal inflammation of the
lining of the nose--swelling of the mlining can lead to closing off of the
normal drainage of a sinuse leading to infection--very similar to closing
off your urinary bladder

not to belabor susan but i doubt she ahs ever prescribed any medication to
any patient nor ahve been held resposible for her advice--please do not
consioder this a flame--same problem for people whio advocate garlic or
cucumber juice for breast cancer or aids

> x-no-archive: yes
>
[quoted text clipped - 13 lines]
>
> Susan

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Susan - 26 Oct 2006 13:55 GMT

> studies have shown that there is a very minumal absorbsion of nasonex

Which causes adrenal suppression.

> if is a very good treatment as it cuts down on naasal inflammation of the
> lining of the nose--swelling of the mlining can lead to closing off of the
> normal drainage of a sinuse leading to infection--very similar to closing
> off your urinary bladder

It's a good short term treatment that causes more harm than good if used
long term.

> not to belabor susan but i doubt she ahs ever prescribed any medication to
> any patient nor ahve been held resposible for her advice--please do not
> consioder this a flame--same problem for people whio advocate garlic or
> cucumber juice for breast cancer or aids

Or idjits who recommend sinus surgery to folks who have had two courses
of antibiotics?

For the record, very few folks here have reported benefits from even
multiple sinus surgeries. That's because the root cause of their/our
chronic inflammation and infection isn't addressed by surgery, too often.

I don't recommend treatments here, but I notice that you do.

Susan

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Steven L. - 25 Oct 2006 03:32 GMT

> x-no-archive: yes
>
[quoted text clipped - 8 lines]
>
> Inhaled steroids cause adrenal suppression,

Intranasal steroids aren't "inhaled," but topically applied to the mucosa.

There is no hard evidence that Nasonex, properly used, causes adrenal
suppression in most adults. The manufacturer warns that this might
happen if either a) the recommended dose is regularly exceeded or b) the
patient is unusually sensitive to it. But even for that, all we have
are a handful of anecdotal case reports, AFAIK.

There is a greater likelihood of adrenal suppression when steroids are
inhaled; e.g., by asthma patients who inhale steroid inhalers down into
their lungs.

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Susan - 25 Oct 2006 14:09 GMT

> Intranasal steroids aren't "inhaled," but topically applied to the mucosa.

True, though one is taught to sniff them in.

> There is no hard evidence that Nasonex, properly used, causes adrenal
> suppression in most adults.

I posted citations demonstrating that all topical steroids do this, even
the ones alleged not to, I think budesonide was one of these.

The manufacturer warns that this might

> happen if either a) the recommended dose is regularly exceeded or b) the
> patient is unusually sensitive to it. But even for that, all we have
> are a handful of anecdotal case reports, AFAIK.

Not so. Have you looked on Medline to back your assertions? I posted
citations supporting mine in this group a few months back. In fact,
these nasal sprays are associated with growth inhibition in children.

> There is a greater likelihood of adrenal suppression when steroids are
> inhaled; e.g., by asthma patients who inhale steroid inhalers down into
> their lungs.

Yes, and higher rates of deaths in those folks, too. The fact that
nasal steroids are less dangerous doesn't make them completely safe.

Susan

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