 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Medical Forum / Diseases and Disorders / Sinusitis / August 2006Bromhexine? (mucolytic-expectorant)
It is a mucolytic-expectorant (one brand name for it-Bisolvon) I read about. Anyone reading used it, or knows something about its efficacy? AFAIK not available in the USA, more common in other countries. Anyone here know something about it? > It is a mucolytic-expectorant (one brand name for it-Bisolvon) I read about. > Anyone reading used it, or knows something about its efficacy? Are you trying to clear thick phlegm out of your airways and lower respiratory tract? (The best way to get thick mucus out of your sinuses remains moisture and irrigation) Bromhexine, along with the more common guaifenisin, are expectorants, supposed to make mucus easier to cough up from the airways. For the lower airways and lower respiratory tract, the few scientific studies that have been done on expectorants have yielded mixed results at best. Expectorants appear to be so weak that you need heavy doses which can cause side effects. It's not clear that expectorants are worth the cost and side effects. On the other hand, true mucolytics that work by chemically dissolving mucus may hold some benefit. Two enzymes that have shown promise are dornase alfa and oral N-acetyl cysteine. AFAIK, dornase alfa is only available by prescription, and it's usually prescribed for more serious illnesses like cystic fibrosis. OTOH, oral N-acetyl cysteine capsules can be purchased OTC in some health food stores or over the Internet. 600 mg 3x day minimum effective dose. http://www.medicine.uiowa.edu/FRRB/VirtualSchool/Ercal-NAC.pdf (you need Adobe Acrobat Reader) N-acetyl-cysteine works well for me and I swear by it.  SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. > On the other hand, true mucolytics that work by chemically dissolving > mucus may hold some benefit. Two enzymes that have shown promise are > dornase alfa and oral N-acetyl cysteine. Oops! I meant to say dornase alfa is an enzyme; N-acetyl cysteine (NAC) is an amino acid. SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. On 8/17/06 5:18 PM, in article pH7Fg.9136$xp2.1089@newsread1.news.pas.earthlink.net, "Steven L." <sdlitvin@earthlinkNOSPAM.net> wrote: >> It is a mucolytic-expectorant (one brand name for it-Bisolvon) I read about. >> Anyone reading used it, or knows something about its efficacy? [quoted text clipped - 25 lines] > > N-acetyl-cysteine works well for me and I swear by it. Green and black tea in large doses also thin mucus. Proteolytic enzymes such as papain and bromelain work too, esp taken via buccal pouch - dissolved in mouth between cheek and gums. Clear-ease papain and bromelane =(my company's product on which I make a PROFIT) was originally developed for scuba divers and pilots to thin the mucus so they could clear their ears. By breaking up the mucus bonds, it thins mucus. . > On 8/17/06 5:18 PM, in article > pH7Fg.9136$xp2.1089@newsread1.news.pas.earthlink.net, "Steven L." [quoted text clipped - 35 lines] > scuba divers and pilots to thin the mucus so they could clear their ears. By > breaking up the mucus bonds, it thins mucus. You're right, I forgot to mention the proteolytic enzymes. Sorry about that. I guess my main point was that expectorants (which are supposed to increase serous "thin" mucus in the airways to lubricate them and make phlegm easier to cough up) haven't lived up to their expectations. SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. >> It is a mucolytic-expectorant (one brand name for it-Bisolvon) I read >> about. Anyone reading used it, or knows something about its efficacy? [quoted text clipped - 15 lines] > mucus may hold some benefit. Two enzymes that have shown promise are > dornase alfa and oral N-acetyl cysteine. Yes, I irrigate a lot. And yes, it's the only thing I've found that really works to loosen mucus. I've taken max dose of guaifenesin for years, and doubt that it helps at all. (I recall once reading a post from you, in which you, however, said that guaifenesin helps you a lot,. Have you changed your mind about it?) I've also tried oral NAC, and doubt it helps. I have never tried bromhexine, have never seen it available, so was curious about it. Have you tried it? Why does it seem not to be available in the USA? >>> It is a mucolytic-expectorant (one brand name for it-Bisolvon) I read >>> about. Anyone reading used it, or knows something about its efficacy? [quoted text clipped - 20 lines] > you, however, said that guaifenesin helps you a lot,. Have you changed your > mind about it?) I still think guaifenisin helped me somewhat (in large doses). But unlike NAC, the scientific evidence for its efficacy is lacking. So I wouldn't recommend guaifenisin to others, based solely on my own personal experience with it. > I've also tried oral NAC, and doubt it helps. I have never tried bromhexine, > have never seen it available, so was curious about it. Have you tried it? > Why does it seem not to be available in the USA? I cannot try bromhexine since it's not available in the U.S. Why, I don't know. SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
|
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2008 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.