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Medical Forum / Diseases and Disorders / Sinusitis / February 2006Is there such a thing as being excessively sensitive to pseudoephedrine at any (practical) dosage?
On my allergist's advice, I am experimenting with liquid pseudoephedrine, in hopes of finding a dose that I won't find overstimulating (and that won't raise my blood pressure, which has gotten high in the past few years). I tried 1/4 tsp. of liquid pseudoephedrine this morning, which should be about 3.75 mg., and yet it still seemed to make me edgy. Maybe it was the caffeine, but my caffeine intake today was comparable to what I have been using lately. It feels like the pseudoephedrine might actually be making me more wired. Is it possible it could even do so at such a low dose? I really don't like the stuff, but it can make a really big difference in clearing up sinus congestion. I'd like to find a useable dose. I've dried the pediatric dose, but when I take one 60 mg. tablet in the morning, it still significantly interferes with my sleep at night, and it tends to make me hyper during the day. (Additionally, it seems to have a cumulative effect, so that if I've been taking it for about a week, I *really* start to have trouble sleeping. I will sleep, but my sleep is extremely shallow, and I find myself spending a lot of time somewhere between being awake and being asleep, and not a pleasant in-between either.) (And yes, I do nasal irrigation regularly, which helps a lot, but has not been a cure for me, not that anyone guaranteed it would be in all cases.) >On my allergist's advice, I am experimenting with liquid >pseudoephedrine, in hopes of finding a dose that I won't find [quoted text clipped - 22 lines] >not been a cure for me, not that anyone guaranteed it would be in all >cases.) Of it will make you more wired. I would not take the stuff. Soem doctors did suggesst it to me. Yes it deso work, but it's systemic effects are too widespread. Let's admit it -it will raise your blood pressure. On 2/18/06 4:14 PM, in article 1140308092.853070.318120@g14g2000cwa.googlegroups.com, "rdrm65@gmail.com" > On my allergist's advice, I am experimenting with liquid > pseudoephedrine, in hopes of finding a dose that I won't find [quoted text clipped - 22 lines] > not been a cure for me, not that anyone guaranteed it would be in all > cases.) Many persons with your type of history seem to do well with Astelin nasal spray. Have you tired this ? Or some will use both the Astelin and the Rhinocort and find good allergy relief. I think I tried Astelin but it was one of those sprays that left a vile aftertaste in my throat for almost 12 hours. I didn't want to put up with it. Possibly the same for Rhinocort. > I think I tried Astelin but it was one of those sprays that left a vile > aftertaste in my throat for almost 12 hours. I didn't want to put up > with it. Possibly the same for Rhinocort. Astelin is not a steroid spray, but an antihistamine spray. Try Flonase aqueous pump spray. I don't think it tastes bad at all.  SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. >> I think I tried Astelin but it was one of those sprays that left a vile >> aftertaste in my throat for almost 12 hours. I didn't want to put up [quoted text clipped - 3 lines] > > Try Flonase aqueous pump spray. I don't think it tastes bad at all. I used to get that awful taste and taste alteration afterward when drinking water, but it went away after consistent use; I've been using Astelin for years with wonderful relief from it. Rhinocort AQ made my nose raw and bloody. Took weeks to heal from it after dc'ing it. Susan > x-no-archive: yes > [quoted text clipped - 12 lines] > Rhinocort AQ made my nose raw and bloody. Took weeks to heal from it > after dc'ing it. See, I had the opposite reaction. it seems that it's very idiosyncratic with these prescription nasal sprays; one person swears by one while another person hates it. It may have to do with sensitivity or mild allergy to one of the inert ingredients in the mixture. SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. On 2/20/06 11:00 AM, in article 45uhv6F8ad61U1@individual.net, "Susan" <nevermind@nomail.com> wrote: > x-no-archive: yes > [quoted text clipped - 14 lines] > > Susan The taste of Astelin is 'bad" but you can take a candy first. Considering that it is not a cortisone, is not a pill that goes to your toes as well as your nose, and avoids all the objections you expressed, I assure you getting accustomed to the taste is well worth it. They have millions of users who all seem to have adapted fine to this product. I find having a peppermint lifesaver in the mouth pretty much masks any taste of the astelin that might drip into the mouth when spraying it into the nose. I decided to give it another try. I picked some up yesterday, used it last night, and didn't even get the bad aftertaste. However, I woke up this morning with heart palpitations and a racing heart. Yes, I do get this occasionally, but I think it's always been in connection to something I am taking. I have been trying a very low dose of pseudoephedrine (7.5 mg.) for a few days now, and I find it hard to believe that amount is causing the trouble. I did not consume more caffeine than usual yesterday. On the face of it, Astelin looks like the culprit. I am going to stop using pseudophedrine altogether for several days, continue the Astelin, and see if the problem persists. Is there anything wrong with using Astelin every day? I haven't tried it yet that often yet. I have been fortunate to work out of my home for the last 5 years. But I have to now go try to work in an office enviornment again, and I dont know if I can survive it. The purfume, smoke smells , etc. make my nasal passageways shut quickly, also triggers migraines. I believe this was the result of excessive surface cauterization. Astelin helps me with keeping my reactions to perfumes and the like at bay. Which is a godsend for me. But I dont know if it will help me in prolonged exposure. As avoidance has been my main sussessful treatment. Also, I have kept swelling at bay at times by putting an ointment I picked up with Capaiscin in it. (it was actually for arthrhitis) I put a small amount of the side of my nose (outside!) and it penetrates and takes the swelling down in my nasal passageways. Weird, I know.....but I'll try anything. >Is there anything wrong with using Astelin every day? Probably not - see http://www.mayoclinic.com/health/allergy-medications/AA00037 but see what others here have to say... >I haven't tried it yet that often yet. I have been fortunate to work >out of my home for the last 5 years. But I have to now go try to work >in an office enviornment again, and I dont know if I can survive it. >The purfume, smoke smells , etc. make my nasal passageways shut >quickly, also triggers migraines. I believe this was the result of >excessive surface cauterization. Maybe but I haver the same reaction and had it even before I had surgery. Best plan another work switch when you can - it does not have to be right now.... > Astelin helps me with keeping my >reactions to perfumes and the like at bay. Which is a godsend for me. [quoted text clipped - 6 lines] >takes the swelling down in my nasal passageways. Weird, I know.....but >I'll try anything. > On my allergist's advice, I am experimenting with liquid > pseudoephedrine, in hopes of finding a dose that I won't find [quoted text clipped - 7 lines] > actually be making me more wired. Is it possible it could even do so > at such a low dose? Yep. Many people are sensitive to it, as you can find out via Google. I'm highly sensitive to it. I can't tolerate even the children's dose. It's a stimulant and it makes me VERY wired. You're definitely making matters worse by taking it concurrently with coffee, which is also a stimulant. Try taking it without drinking any coffee. Or switch to decaf for the present. You may find that you're mildly hooked on caffeine, so that when you give up caffeinated coffee, the pseudoephedrine boost may actually ease your caffeine withdrawal and all will be good. You certainly don't need a morning coffee to get you started if you're on pseudoephedrine. :-) > I've dried the pediatric dose, but when I take one 60 mg. tablet in the > morning, it still significantly interferes with my sleep at night, and > it tends to make me hyper during the day. (Additionally, it seems to > have a cumulative effect, so that if I've been taking it for about a > week, I *really* start to have trouble sleeping. Yep, it can have a cumulative effect too. SignatureSteven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me. > > On my allergist's advice, I am experimenting with liquid > > pseudoephedrine, in hopes of finding a dose that I won't find [quoted text clipped - 30 lines] > > Yep, it can have a cumulative effect too. I must be strange, because every time I take Sudafed I get very sleepy--not wired. I do get a funky disembodied, fuzzy-headed feeling about 4--6 hours after taking the stuff. But, if I'm having sinus problems, it does help a lot.--r3 > I must be strange, because every time I take Sudafed I get very > sleepy--not wired. That used to happen to me, too. I've been told this can be a sign of low adrenal function, but I've never researched it. Susan
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