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Medical Forum / Diseases and Disorders / Sinusitis / October 2005

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Does my child still need antibiotic treatment?

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Chin Gao - 22 Oct 2005 21:23 GMT
Hi All,

Hoping for some help. As short as  can! -- my daughters (5 yrs) is
allergic to penicillen drugs. Three weeks ago, she'd had a cold that
was getting worse and so on day 7 we took her to the Pediatrician. She
saw a different one but he said sinus infection and gave her Zithromax.

Filled the RX, had it flavored with Flavorx, within hours, she was
covered with hives. Sun Pedia said no more antibiotics, she'll just
need to fight it out on her own.
Stopped the meds, Benydryl and three days later managed an appointment
with the allergist. Allergist scheduled CT scan for three days later.
They called back and said CT scan shows 5-7 mm thickening in the
Maxillary and Ethoid sinus passages. (spelling probably off!) So, a
different allergist in the office gets the reposrt and prescribes
Cleocin (liquid Clyndomyacin). She takes it for five days, new bottle
is flavored, she breaks out in 80% hives.
The regular pediatrician says she doesn't know, just do whatever the
allergist says. The allergist put her on Benydryl and Prednisone. She
is supposed to go back in next week and have an antibiotic challenge to
determine whether she's allergic to the Cleocin or the Flavorx. Either
way, the plan is to put her back on the antibiotic for a few weeks;
either with Prednisone and Benydryl or without.
Thus far, from the time she first went to see the doctor it's been 2
weeks. She has had ZERO symptoms in 12 days. So the question is this.
Does she even have a sinus infecton anymore? I mean, she has no
symptoms and it very likely could have been viral in nature in the
first place. I suppose I'd like to know what you all think about
medicating a small child for weeks when they show no signs of being
ill. I know that a CT scan is only supposed to be used diagnostically
with symptoms and not alone. Any advice would be appreciated.
Thanks
Woody Long - 23 Oct 2005 21:10 GMT
I suppose I'd like to know what you all think about
> medicating a small child for weeks when they show no signs of being
> ill.

I think it it make the child chronically ill for the rest of its life
in cases where this would not have happened without the antibiotic.

http://www.msnbc.msn.com/id/5075895/

Woody

By Tom Webb

In ever-growing numbers, something seems to be poisoning America's
kids. But what?

Rates are soaring for diagnoses of childhood asthma, autism, allergies
and attention deficit hyperactivity disorder. Scientists don't fully
understand what's happening among this generation of children - but
they're worried by a mounting toll of sick kids and the growing costs
to families, schools, taxpayers and society.

In Minnesota, autism diagnoses alone have grown twentyfold in a
generation, making a once-rare condition an unhappy fact of modern
life.

Now, the federal government hopes to unravel the mystery, by launching
the largest study of children in U.S. history. It's called the National
Children's Study, a two-decade-long effort that would track 100,000
children from the womb into adulthood, examining their genetic makeup,
environment, eating habits, home situations and health. The cost: a
massive $2.7 billion.

"It's big science. It's the same order of magnitude as the human genome
project," said Dr. Peter Scheidt, director of the study's program
office, at the National Institute of Child Health and Human
Development.

The study seeks to answer questions now raging within medical circles,
among educators and in parent groups. Are these conditions caused by
toxins? By genetics? Too much television? Bad diets? Home situations?
Possibly some combination?

It has many supporters, who cite the staggering cost both in medical
care and in the impact on families; they welcome the effort to
systematically explore why this is happening. But in Washington, the
competition for research dollars is always fierce, and even some
children's advocates are unsure the data produced will be worth the
cost.

Mary Powell, director of the Autism Society of Minnesota, would welcome
some answers. In the past 15 years, she has seen an explosion in the
number of Minnesota kids diagnosed with autism-related conditions, from
about 100 children to nearly 3,000. Some of that growth reflects better
diagnosis of autism, but she suspects something else is happening, too
- with troubling consequences.

The root cause of autism is "the nagging question forever for parents,"
Powell said, "because they're always saying, 'If there's something I
could have done.' That's a very profound question in parents' minds
because they never get rid of the feeling that, somehow, the course of
their children's life could have been different."

For Gretchen Moen of Eagan, it's asthma that has altered her family's
life.

Her athletic son, Patrick, now 18, has asthma, and she vividly
remembers the early struggles.

"When you have a kid with a chronic illness, it affects everybody in
the family," she said. "He missed probably half of kindergarten, and
half of first grade" because he was too sick to attend school. "He was
the kind of kid who'd get a cold, and it would last him the entire
winter."

Her son's story does have a happy ending: with determination,
medication and some allowances, Patrick has become a star athlete at
St. Thomas Academy.

But his mother remembers the worry, too.

"There were many, many nights when you'd stay up all night listening to
your child breathe, just to make sure he keeps breathing."

UNEXPLAINED INCREASE

Despite much medical detective work, scientists still do not fully
understand the soaring rates for childhood asthma, allergies, attention
deficit hyperactivity disorder and several other health conditions.
Even childhood obesity, although better understood, has elements that
remain puzzling.

"They're all conditions that are pretty common in children, and are
increasing," Scheidt said, "and clearly there are multiple factors that
are contributing to these conditions - genetic predisposition,
behavior, environmental exposures, the way they're managed.... How they
contribute, and how they interact, we really don't have a very good
handle on. You need to measure them carefully, you need to study them
over time ... and you can only do it with a very large study, to
separate out the groups and subgroups."

Minnesota school districts large and small are struggling to meet the
ever-rising demand for expensive services. Chris McHugh with the St.
Croix River Education District sees a surge there in children with a
spectrum of autism disorders.

"We're certainly seeing an increase that is rather inexplicable to us,"
McHugh said. "It's probably not the big increase as in urban areas, but
it's certainly putting a strain on our resources, because these kids
need very individualized resources."

Ann Hoxie has been a school nurse in the St. Paul public schools for 20
years. Like many front-line professionals, she's seeing much more
childhood asthma. In St. Paul, it afflicts at least 8 percent of the
students. In Minneapolis, it's 12 percent.

"Last fall was a bad allergy season, and we had lots of kids having
problems with asthma, and a fair number of 911 calls, just because we
didn't have the right meds for kids. We didn't see nearly so much of
that 20 years ago," said Hoxie, the district's administrator for
student wellness. "We had a student die of asthma last year. Students
don't die at school! But we did have that happen."

Officials frequently ask themselves, what's causing all this?

"All of these things existed before, but it's the volume that we see,"
Hoxie said. "We do question it, but we're kind of busy responding. And
it's not just here in Minnesota. It's everywhere."

The children's study won't focus solely on those problems. It will
examine many aspects of child development - including family
structure, ethnicity, prenatal care and family income. The hoped-for
answers run the gamut, too, with researchers craving insights into the
causes of cerebral palsy, schizophrenia and other conditions.

Still, the urgency is being driven by unexplained spike in childhood
conditions. Dr. Duane Alexander, director of the National Institute of
Child Health and Human Development, last month told a Casey Journalism
Center seminar that if even some answers emerge, the study's cost will
be more than covered.

The study itself was authorized by Congress back in 2000, but the tough
part will be finding the money in the federal budget.

The real money crunch will come in a year, maybe two, Scheidt said,
when hundreds of millions of dollars will be needed to start
recruiting, then interviewing and tracking, 100,000 parents.

If it works as planned, the study will begin churning out some answers
in about five years. Advocates hope it will uncover both what is
harmful - and what is not. That's one reason the study is endorsed by
children's advocacy groups, as well as the American Chemistry Council,
which feels its products are sometimes unfairly blamed.

UNCERTAIN OUTCOME

Dr. Sheldon Berkowitz, medical director at Children's Hospitals and
Clinics in Minneapolis, notes that studies on this scale are unique and
don't always follow predictable lines, so he's a bit wary about the
talk of finding root causes.

"The grand scale of it is what's so overwhelming," Berkowitz said of
the study. "My guess is that, with a study like this, you're going to
have a whole lot of things falling out of this that you never really
expected ... and you may be disappointed on stuff that you hoped to
get."

Berkowitz wondered if a smaller study might be adequate, noting, "I
wonder if $2.7 billion is best spent in this way, when there's all
these immediate pressing needs for kids."

Scheidt explained that with 100,000 children, researchers will be able
to examine large subgroups to compare and contrast.

If researchers want to know why 8-year-old middle-class Hispanic boys
have high rates of asthma, scientists can examine a lifetime of health
and child-development data for such a group - and a parallel group of
8-year-old middle-class Hispanic boys who don't have asthma. Why did
one group get it, and the other did not? What's different?

"Because we have such a large study, we will be able to obtain and find
a control group that is comparable," Scheidt said. "It is the size of
the study that will enable us to do that. And that will allow us to
draw conclusions."

If the study pins down some hard-to-define problems, that may be
useful, too. Thomas Dickhudt, superintendent of the Chisago Lakes
school district, knows that more kids are being diagnosed with autism
and Attention Deficit Hyperactivity Disorder, but he wonders: Are there
more sick kids, or just changes in how kids are diagnosed?

"That's the part I'm having trouble with," he said.

Dickhudt, however, clearly sees more problems with asthma and allergies
among his students. His 3,500-student Chisago Lakes district is
spending $2 million to improve air quality in five of its buildings,
upgrading air circulation, ventilation, carpets, and dehumidifiers.

"It's a very high expense for our district," Dickhudt said. With dust,
mold and air quality issues, "There does seem to be a greater
sensitivity among people."

The U.S. Department of Education tracks soaring rates of
attention-deficit and hyperactivity disorder. A decade ago, 83,000 U.S.
students were counted in a broad category that included the syndrome.
Last year, that had increased nearly fivefold.

"We estimate that at least one student in every classroom had
(attention deficit disorder) or (attention deficit hyperactivity
disorder)," said Jim Bradshaw, an Education Department spokesman.

Moen is active in the Minnesota Asthma Coalition, where each year she
sees more and more kids with asthma - reflecting better diagnosis,
she says, but perhaps something more.

She would welcome answers to fears that bedevil a million parents.

"Are we doing something to our children, so to speak, that has caused
this? I think that's what everybody wants to know."

The U.S. Department of Education tracks soaring rates of
attention-deficit and hyperactivity disorder.

A decade ago, 83,000 U.S. students were counted in a broad category
that included the syndrome. Last year, that had increased nearly
fivefold. Rates are soaring for diagnoses of childhood asthma, autism
and allergies as well.
Steven L. - 25 Oct 2005 02:20 GMT
> Hi All,
>
[quoted text clipped - 27 lines]
> ill. I know that a CT scan is only supposed to be used diagnostically
> with symptoms and not alone. Any advice would be appreciated.

My ENT has told me that he has some sinusitis patients who are allergic
to all antibiotics.  For them, surgery, topical nasal steroid sprays and
nasal irrigation are the best options.

If none of your physicians has yet prescribed nasal irrigation and
topical nasal steroid sprays for your daughter, you should talk about it
with them.  Combined with allergy treatment, that may bring her sinus
problems under long-term control.  If not, then surgery is always an
option too.

Good luck.

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Boron Elgar - 25 Oct 2005 15:41 GMT
>My ENT has told me that he has some sinusitis patients who are allergic
>to all antibiotics.  For them, surgery, topical nasal steroid sprays and
>nasal irrigation are the best options.

Being allergic to "all antibiotics," would be quite rare, as there are
so many distinct and different classes of them. Additionally, the
danger of such a situation is evident. Surgery is not to be undertaken
as lightly as a course of antibiotics.

And to have multiple patients with the same unusual allergy is, in
itself, an oddity.  Perhaps you misunderstood your ENT.

Boron
Steven L. - 25 Oct 2005 22:46 GMT
>>My ENT has told me that he has some sinusitis patients who are allergic
>>to all antibiotics.  For them, surgery, topical nasal steroid sprays and
>>nasal irrigation are the best options.
>
> Being allergic to "all antibiotics," would be quite rare, as there are
> so many distinct and different classes of them.

The 6 most commonly prescribed classes of antibiotics for sinusitis are:
 Penicillins, cephalosporins, macrolides, sulfas, quinolones, and
clindamycin.  And you can certainly be allergic to all six.

> Additionally, the
> danger of such a situation is evident. Surgery is not to be undertaken
> as lightly as a course of antibiotics.
>
> And to have multiple patients with the same unusual allergy is, in
> itself, an oddity.  Perhaps you misunderstood your ENT.

No, I asked him several times.  He said that there are no antibiotics at
all they can take, making surgery life-threatening for them.  It is
rare.  But my ENT's medical group has had many thousands of patients,
and seen many unusual things.

I'm getting there myself.  So far, I'm allergic to penicillins,
cephalosporins, and clindamycin.  The macrolides and sulfas no longer
work on my infections.  So for my sinus infections, the quinolones are
my last chance.  When I had surgery, my surgeon had trouble finding an
IV antibiotic to give me.  He finally found IV Cipro.

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Preesi - 25 Oct 2005 23:03 GMT
>>> My ENT has told me that he has some sinusitis patients who are
>>> allergic to all antibiotics.  For them, surgery, topical nasal
[quoted text clipped - 24 lines]
> my last chance.  When I had surgery, my surgeon had trouble finding an
> IV antibiotic to give me.  He finally found IV Cipro.

You had surgery too, right Steven?
See, thats why I didnt have it, what was the point if you still get
sick.

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Steven L. - 26 Oct 2005 00:02 GMT
>>>>My ENT has told me that he has some sinusitis patients who are
>>>>allergic to all antibiotics.  For them, surgery, topical nasal
[quoted text clipped - 26 lines]
>
> You had surgery too, right Steven?

Twice so far.
It hasn't cured me but it has greatly relieved my symptoms.  I was
literally gagging and choking on my own secretions before.

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Boron Elgar - 26 Oct 2005 00:41 GMT
>>>My ENT has told me that he has some sinusitis patients who are allergic
>>>to all antibiotics.  For them, surgery, topical nasal steroid sprays and
[quoted text clipped - 6 lines]
>  Penicillins, cephalosporins, macrolides, sulfas, quinolones, and
>clindamycin.  And you can certainly be allergic to all six.

If you wish to know more about them, look here:

http://tinyurl.com/alfvk

or here:

http://www.tufts.edu/med/apua/Miscellaneous/common_antibiotics.html

Would you care to offer a citation as to the incidence of allergy to
"all antibiotics" so as to disprove my claim that it is rare?

>> Additionally, the
>> danger of such a situation is evident. Surgery is not to be undertaken
[quoted text clipped - 13 lines]
>my last chance.  When I had surgery, my surgeon had trouble finding an
>IV antibiotic to give me.  He finally found IV Cipro.

You are anecdotal.  It does not matter what works with you and what
you are allergic to. You made two sweeping claims. Provide citations
to back them up.

Boron
Susan - 26 Oct 2005 01:29 GMT
> You are anecdotal.  It does not matter what works with you and what
> you are allergic to. You made two sweeping claims. Provide citations
> to back them up.
>
> Boron

This is alt.support, not sci.med.

Cut a little slack for the anecdotal, yes?

Susan
Boron Elgar - 26 Oct 2005 01:42 GMT
>x-no-archive: yes
>
[quoted text clipped - 9 lines]
>
>Susan

Bullshit is bullshit, no matter what group it is on.  

Boron
Susan - 26 Oct 2005 01:47 GMT
> Bullshit is bullshit, no matter what group it is on.  
>
> Boron

Well, fortunately for us, you're not our moderator.

But thank you for playing!

Susan
Boron Elgar - 26 Oct 2005 02:12 GMT
>x-no-archive: yes
>
[quoted text clipped - 7 lines]
>
>Susan

Those who defend foolishness and inaccuracies in a med related support
group are counterproductive. If you do not know your a.s from your
elbow. find someone who can identify them for you.

Boron
Susan - 26 Oct 2005 02:22 GMT
> Those who defend foolishness and inaccuracies in a med related support
> group are counterproductive. If you do not know your a.s from your
> elbow. find someone who can identify them for you.
>
> Boron

I'm quite sure I've forgotten more medical information than you'll ever
know.

Sorry that someone pissed in your Post Toasties today.  Do you have
problems with your sinuses that you'd like to discuss, or are you a full
time Flame Thrower?

Susan
Steven L. - 26 Oct 2005 04:07 GMT
> Those who defend foolishness and inaccuracies in a med related support
> group are counterproductive. If you do not know your a.s from your
> elbow. find someone who can identify them for you.

With all due respect,
I believe I "know my a.s from my elbow" when it comes to chronic sinusitis.

Would you like to compare your knowledge against mine?

This is the last chance you will get.
In 48 hours you're going to be consigned to my killfile, from which
there is no escape.

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Steven L. - 26 Oct 2005 04:06 GMT
>>>>My ENT has told me that he has some sinusitis patients who are allergic
>>>>to all antibiotics.  For them, surgery, topical nasal steroid sprays and
[quoted text clipped - 17 lines]
> Would you care to offer a citation as to the incidence of allergy to
> "all antibiotics" so as to disprove my claim that it is rare?

I said it was rare.

I'll be happy to email you the name, address, and telephone number of my
ENT.  Would that satisfy you?

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sedum41 - 26 Oct 2005 15:45 GMT
I would think the ENT doctor would treat based on symptoms not CAT scan
results. If she doesn't have thick, green mucous or fever she probably
doesn't have an infection. Thickened sinus membranes without the mucous
are a result of allergies.

As other posters have suggested you should consult an allergist and get
your daughter skin tested for allergies. At the same time, the allergy DR
can check her for antibiotic allergies too using blood tests especially as
she already shows reactions to penicillian antibiotics. Once you find out
the results of the allergy tests, there are many medicines and allergy
shot treatments that can greatly relieve the symptoms. Also there are many
non medical things you can do to reduce allergies by changing the
environment of your child's bedroom. Such things include removing heavy
curtains, stuffed animals, getting dust-mite proof covers for
pillows/mattresses, removing wall to wall carpeting and installing
hardwood or non rug floor covering (tile/linoleum), decluttering the room,
frequent washing pillows and bedding in hot water to kill dust mites, etc.
You allergist should have suggestions once she is tested.

May be you could consult a major medical center near you and see if there
is an ENT doctor that specializes in treating children. I would be very,
very cautious about anyone suggesting surgery - I believe I read that a
child's sinus passageways aren't fully developed until the teen years.
Steven L. - 26 Oct 2005 16:44 GMT
> I would think the ENT doctor would treat based on symptoms not CAT scan
> results. If she doesn't have thick, green mucous or fever she probably
[quoted text clipped - 14 lines]
> frequent washing pillows and bedding in hot water to kill dust mites, etc.
> You allergist should have suggestions once she is tested.

And parents should give up smoking.  Not just for themselves, but for
their kids.
My mom was a chain smoker, even when she was around me as a toddler.
And looking back on it, I'm pretty sure the second-hand smoke
exacerbated my asthma and croup attacks.

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sedum41 - 26 Oct 2005 18:03 GMT
Yes, definitely agree second hand smoke exposure is a major problem for a
child's development of ear infections, sinus and asthma. My parents smoked
in the 1960's like every other adult. I guess I was lucky they quit when I
was 3 years old when one of them got a bad case of pneumonia! Now on the
other hand, my husband grew up in a home where both parents smoked (and
still do) and he has no sinus or allergy problems.
Chin Gao - 26 Oct 2005 21:41 GMT
Thanks for the advice. The allergist office wants to set up an
antibiotic challenge but they said she has to be hive free for two
weeks before they can do it. The nurse said they would give her a small
amount of the Cleocin and monitor, then more and so on until she has
acheived a full dosage without reaction.
What I really don't understand, and I suppose I need to do some
research, is the point of an antibiotic challenge. If she takes the
Cleocin with no Flavorx and has no reaction, then the assumption is
that she can take Cleocin with no adverse effect. But I thought that
the more someone is exposed to an allergen the more likely their
chances of reacting in the future. Just confused as to whether we're
setting her up for a future fall no matter what.
But, so far as the sinus infection is concerned, she has no issues at
all right now. And, as she's finally getting the Prednisone out of her
system, is beginning to act more like herself.
BTW, someone had suggested a Steroidal Nasal Spray. Thanks. I talked to
the office about that and the nurse said that would certainly be a
better option next time. Also, we're going to pull her off daily doses
of Dytan and try a more mucosal thinning one.
All comments are greatly appreciated. I've had virtually no experience
with sinus problems but I'm learning!
Steven L. - 26 Oct 2005 21:53 GMT
> Thanks for the advice. The allergist office wants to set up an
> antibiotic challenge but they said she has to be hive free for two
[quoted text clipped - 8 lines]
> chances of reacting in the future. Just confused as to whether we're
> setting her up for a future fall no matter what.

I don't understand the urgency of the Cleocin challenge at this time.
Did you ask the allergist office why it has to be done in the next few
weeks?

Your child has already been thru hell, it sounds like, and maybe she
could use a nice vacation.  :-)

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Chin Gao - 26 Oct 2005 22:09 GMT
More than anything I would like to have an entire week of normalacy.
We've been going through something with her since October 2 but it
feels like months!
They said that we need to test her as soon as possible because we need
to know what she can and cannot take. My husband thinks we should just
leave her alone for a while and let her just get back on a normal
(non-sick/non-hive) schedule.
Of course, the office is porbably none too pleased with me right now. I
don't think they liked it when I said that I didn;t feel there was a
need for antibiotics at this time. They all seem to be basing the
diagnosis on the CT alone and I had understood that a CT scan is to be
used in 'conjuction' with symptoms. Additionally, can't a CT scan show
mucosal thickening for weeks after sinusitus is resolved?
So, yes, I think she, and the whole family, could really use a break
right now!
Boron Elgar - 26 Oct 2005 22:10 GMT
>Thanks for the advice. The allergist office wants to set up an
>antibiotic challenge but they said she has to be hive free for two
[quoted text clipped - 17 lines]
>All comments are greatly appreciated. I've had virtually no experience
>with sinus problems but I'm learning!

Though the site linked below is Australian, and some specific brand
names name differ,  it will give you some background on antibiotic
allergy and challenge testing.

http://www.allergy.org.au/aer/infobulletins/hp_antibiotics.htm

Basically, the problem is that patient reported allergy to antibiotics
is overestimated. Direct observation of an allergic reaction to an
antibiotic by a physician  is more accurate, but is still not
fool-proof. Since it is important for the physician to be able to
treat with the most effective antibiotic, a challenge test can more
accurately determine if an allergy is actually present.

The following links may provide more background.
http://pediatrics.aappublications.org/cgi/content/full/104/2/S1/367

http://www.aaaai.org/professionals/resources/rgce/guidelines.asp?group=Drug+Allergy

The  above link says:

"Guideline:
Patients with a history of penicillin allergy who have a significant
probability of requiring future antibiotic therapy.

Rationale:
The vast majority of patients with a history of penicillin allergy can
safely use penicillins if an allergy evaluation, often including a
penicillin skin test, is performed. 1

History alone is inadequate to rule out IgE mediated allergy to
penicillin. 2

Penicillin skin testing in advance of need does not cause significant
re-sensitization. 3-6

Patients who are shown not to be allergic to penicillin may be able to
use more appropriate and potentially less toxic and/or expensive
antibiotics. "

Boron
Chin Gao - 26 Oct 2005 23:30 GMT
Thank you. These are good starting points.

The allergist did see her shortly after taking the Cleocin when she was
about 80% covered with hives. I'm still not convinced it was the
medication, but lean more towards the Flavorx as the culprit.

I would love to find out that there are antibiotics that she can safely
take. My fear is her having a negavtie reaction in the office and then
later being given the medication and having a severe reaction as a
result of too many exposures.

Thanks again
Boron Elgar - 27 Oct 2005 00:04 GMT
>Thank you. These are good starting points.
>
[quoted text clipped - 8 lines]
>
>Thanks again

A negative on the challenge would indicate that she is not allergic to
the particular antibiotic and no harm to her if she takes the med. If
it is positive, there should not be a significant increase in
sensitivity, but you will have a confirmation that she is allergic to
that particular antibiotic and that it should not be prescribed for
her.

It is also important to understand if she is allergic to the Flavorx
or similar, That is more likely for the allergist to determine.

Hives can be odd reactions, sometimes brought on by a virus...not
necessarily "caused" by the virus, but the virus can sensitive the
immune system into reacting to some trigger.  Sometimes the cause of
hives is never found out. They can be intermittent or chronic.

Boron
Chin Gao - 27 Oct 2005 00:18 GMT
Okay. I thought that it might be dangerous even if she has no reaction.
My understanding was that the more she was exposed to something the
more likely a reaction would be later.

She does have hives from odd things though. A fireant bite looks as if
she's been burned. Sometimes, just playing outside will cause her face
to be covered and sometimes, they just appear for a few days with no
apparent cause.

It's very odd for me. I personally have an IGE anti-IGA auto-antibody
disorder. I haven't had a day in three years without hives. But
according to my immunologist and allergist, it's a non-communicable
condition so it would be completely unrelated to her problem.

Sometimes lately, I feel like I'm never going to find any answers.
We're hesitating on a trip out of the country next Spring. My husband
is afraid that she'll become sick and the doctors there (SE Asia) will
have no idea how to deal with her.

Glenda
Steven L. - 27 Oct 2005 03:04 GMT
> Okay. I thought that it might be dangerous even if she has no reaction.
> My understanding was that the more she was exposed to something the
[quoted text clipped - 9 lines]
> according to my immunologist and allergist, it's a non-communicable
> condition so it would be completely unrelated to her problem.

By "non-communicable" do you mean "non-inheritable"?
Because a number of autoimmune disorders do seem to run in families:

http://tinyurl.com/awced

> Sometimes lately, I feel like I'm never going to find any answers.
> We're hesitating on a trip out of the country next Spring. My husband
> is afraid that she'll become sick and the doctors there (SE Asia) will
> have no idea how to deal with her.

Ah.  If you're traveling to foreign countries, it's worth getting things
under control first.  It would be worth knowing what antibiotics your
daughter can safely take before you leave the country.  Just in case.
Still, I would imagine that the Cleocin challenge could be postponed a
while and still leave plenty of time at the other end for your trip.

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Chin Gao - 27 Oct 2005 03:43 GMT
Hi Steven,

Yes, I suppose I mean that I can;t infect anyone or pass it along. Mine
started a few years back when my immune system was compromised due to
an allergic reaction. I have chronic urticaria, angiodema and delayed
pressure urticaria. I know my way around Prednisone and Benydryl among
a slew of other allergy meds! No one else in my family has ever had any
issues at all like mine and it's a bit "freakish" sometimes.

I think you all are right though; the antibiotic challenge needs to be
done but I think I'll hold off and just get her back on a normal
shedule for a while. She may very well need it -- especially if she has
a reaction,

Glenda
Boron Elgar - 27 Oct 2005 14:27 GMT
>Okay. I thought that it might be dangerous even if she has no reaction.
>My understanding was that the more she was exposed to something the
[quoted text clipped - 4 lines]
>to be covered and sometimes, they just appear for a few days with no
>apparent cause.

Once the immune system is aroused, allergen and/or triggers can more
easily get it to overreact.

I had hives daily for over 10 years without anyone being able to find
out what caused them. Ultimately I wound up with 2 autoimmune
disorders. Likely no direct connection, but all are symptomatic of an
immune system in fighting mode.

>It's very odd for me. I personally have an IGE anti-IGA auto-antibody
>disorder. I haven't had a day in three years without hives. But
>according to my immunologist and allergist, it's a non-communicable
>condition so it would be completely unrelated to her problem.

Auto immune "over" reactions can run in families. The predisposition
can be genetic.

>Sometimes lately, I feel like I'm never going to find any answers.
>We're hesitating on a trip out of the country next Spring. My husband
>is afraid that she'll become sick and the doctors there (SE Asia) will
>have no idea how to deal with her.
>
>Glenda

Consulting with her pediatrician and an allergist, and assuming she is
stable at the time of the trip, you can probably take certain meds
with you to tide you over. It will all be up to the MDs, though,
whether that is safe. You can also try ahead of time to find an
allergist and pediatrician in the area in which you will be traveling.
Universities are often good connections and your medical staff here
may be able to help you make some.

Boron
sedum41 - 26 Oct 2005 16:26 GMT
In my last post I meant to say:

Thickened sinus membranes without the mucous discharge can be a result of
allergies or inflammation.
Don Brady - 27 Oct 2005 00:54 GMT
>Hi All,
>
[quoted text clipped - 27 lines]
>ill. I know that a CT scan is only supposed to be used diagnostically
>with symptoms and not alone. Any advice would be appreciated.

A CT scan can tell a lot.   That is a lot of thickening.  Is there a lot of
dust or mold in the house?   I would not argue with the CT scan as such.

But you have a right to stop the medications and tests and challenges and
treatments and see what happens for a while, if you want, especially since she
seems ok now.

Just tell the doctors that that is what you would like to try.  I think that
you will find that they will accept that if you take the responsibility for the
decision, since the child is symptom free at the moment.

You would need to taper off the prednisone if she is still taking that.  You
cannot just stop that cold.   So you would need tapering  instructions if you
want to taper that off.  

You can always get second opinions too or switch to another doctor.

You certainly do need to identify the cause of the thickening but if symptoms
are ok now for 12 days then I think you could postpone further testing for a
while to see how things go.....
Chin Gao - 27 Oct 2005 03:36 GMT
Right; it is a significant amount of thickening. It's not that I think
the CT scan is wrong exactly. It's just that what I'm reading says that
the CT scan has to be used with symptoms. Also, her sinusitis could
also have been viral in nature and therefore needs no antibiotics.

I will talk to the doctor when he gets back from vacation since the
substitute wouldn't look at her because she still had hives. It just
seems really hard to get a straight answer lately...Of course, maybe
there just aren't any easy ones.

She's just finished the last dose of Prednisone Monday and today only
had a few hives. Other than a headache tonight, all seems to be moving
forward. I just keep reading and searching symptoms and complications.
One of my big fears is that we're wrong and she has some sort of deep
seated sinus infection that will rebound any day now.

Thanks very much, I'll just keep monitoring...
Steven L. - 27 Oct 2005 16:33 GMT
> Right; it is a significant amount of thickening. It's not that I think
> the CT scan is wrong exactly. It's just that what I'm reading says that
> the CT scan has to be used with symptoms. Also, her sinusitis could
> also have been viral in nature and therefore needs no antibiotics.

Actually, with all forms of acute sinusitis, studies show that about 40%
of cases will clear spontaneously eventually.  Especially with
irrigation, steroid nasal sprays and aggressive treatment of causes like
allergies.

> I will talk to the doctor when he gets back from vacation since the
> substitute wouldn't look at her because she still had hives. It just
[quoted text clipped - 6 lines]
> One of my big fears is that we're wrong and she has some sort of deep
> seated sinus infection that will rebound any day now.

If the sinus ducts are open, and all she has is thickening of the
linings, a steroid nasal spray could keep that under long-term control.
 So I still think that this medication (along with aggressive treatment
of causes like allergies, air pollution, etc.), could turn out to be her
best bet right now.

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Chin Gao - 27 Oct 2005 17:05 GMT
Her sinus ducts are open, just the thickening seems to be the main
issue. I've washed everything in her room and we're trying to keep dust
to a minimum.
Right now, we're looking into air filter systems. The ionizer ones
scare me a little. What I'd like to find is a HEPA type with a filter
that I can clean and not replace every 2 weeks.
Preesi - 27 Oct 2005 18:11 GMT
>> Right; it is a significant amount of thickening. It's not that I
>> think the CT scan is wrong exactly. It's just that what I'm reading
[quoted text clipped - 6 lines]
> irrigation, steroid nasal sprays and aggressive treatment of causes
> like allergies.

Steven?
Has that ever happened to you?

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iJah - 30 Oct 2005 20:46 GMT
>Hi All,
>
>Hoping for some help. As short as  can! -- my daughters (5 yrs) is
>allergic to penicillen drugs. Three weeks ago, she'd had a cold that
>was getting worse and so on day 7 we took her to the Pediatrician. She
>saw a different one but he said sinus infection and gave her Zithromax.

<snip>

> I suppose I'd like to know what you all think about
>medicating a small child for weeks when they show no signs of being
>ill. I know that a CT scan is only supposed to be used diagnostically
>with symptoms and not alone. Any advice would be appreciated.
>Thanks

Chin Gao,

All I can tell you, from my personal experience, is that taking
medications - *especially antibiotics* - when they are not really
needed is a huge mistake.

Maybe you already know, but antibiotics not only kill 'bad bacteria',
but they are also extremely effective at killing off all the 'friendly
bacteria' in the digestive system. Just a few courses of antibiotics
in the past have left me (and others I've known) with quite nasty
consequences. My digestive system just became completely dysfunctional
and I developed a very nasty systemic 'yeast' infection which had a
terrible impact on my overall health and really did a lot of damage to
my immune system as well.

Basically, what you need to be very aware of is that antibiotics
destroy 'friendly bacteria' in the digestive system and make sure that
your daughter eats plenty of yogurt and/or takes supplements with
acidophilus and other 'friendly bacteria' to keep her digestive system
functioning normally.

Doctors rarely tell you anything about this potentially severe
consequence of using antibiotics.

Good luck with your daughters problem

iJah

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