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Medical Forum / Diseases and Disorders / Sinusitis / June 2005

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Question on histamines/effects

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Geronimo - 18 Jun 2005 20:20 GMT
WHen my sinuses get severely congested, I can only clear them by
"sucking" the secretions down, inhaling abruptly through the nose,
making that awful and embarassing snort noise.  At the same time that
the congestion gets bad, and I am clearing (or attempting to clear)
the sinuses almost constantly, my salivary glands seem to go into
overdrive, and so I have to have a cup handy, because it is far too
much to swallow it all.  I understand that the sinus irritation
releases histamines, which makes the sinuses secret mucous.  But do
histamines also stimulate the salivary glands? Perhaps the body trying
to flush out foreing irritants from the mouth as well? Also, do
histamines stimulate the nervous system, inhibiting sleep?
  What antihistamine or decongestant usually works best for people
with  a fungal sinusitis?
Don Brady - 18 Jun 2005 20:56 GMT
>   What antihistamine or decongestant usually works best for people
>with  a fungal sinusitis?

Antihistamines and decongestants may not be the best options.

Consider a nasal steroid spray - a much safer choice in my opinion.
Geronimo - 19 Jun 2005 03:24 GMT
 Are nasal steroid sprays prescription or OTC?
 I think Mayo clinic is in CHicago, it isn't financially possible to
go there. Just going to Houston would be very  difficult.

As for antihistamines drying in place any infection....well, since so
far no decongestant or antihistamine seems to relieve/dry out/clear my
sinuses, even when taken at more than recommended dosage, its not an
issue right now.

  The other angle I am trying to research is whether asthma,
allergies, and sinus problems are significantly worse in urban areas
where there is air pollution and smog. I am almost certain they are.
If I don't have a fungal infection, then it could be I am reacting to
some pollutant in the air. I would like to test for that by taking a
vacation trip to Bora Bora for a couple of months   ;-)
  But since the sinusitis is bad all day, every day, and doesn't seem
to be related to the season, or get better as the quality of the air
improves  temporarily, it kind of points to an infection.

>>   What antihistamine or decongestant usually works best for people
>>with  a fungal sinusitis?
>
>Antihistamines and decongestants may not be the best options.
>
>Consider a nasal steroid spray - a much safer choice in my opinion.
Don Brady - 19 Jun 2005 04:14 GMT
>  Are nasal steroid sprays prescription or OTC?
>  I think Mayo clinic is in CHicago, it isn't financially possible to
>go there. Just going to Houston would be very  difficult.

They are in Florida.Minnesota and Arizona.

But they are certainly npt h

>As for antihistamines drying in place any infection....well, since so
>far no decongestant or antihistamine seems to relieve/dry out/clear my
>sinuses, even when taken at more than recommended dosage, its not an
>issue right now.

No no no.  I mean antihistamines tend to  thicken and dry the mucus to the
point that it *cannot* drain.  It gets stuck right where it is, which is why
you cannot clear it.   Draining is how the sinuses clean themselves.  The point
is not that drying out the sinuses is good.  The point is that it is bad.  

Drying out and clearing are not synonyms.  They are opposites (in many cases).

The antihistamines may be *causing* part of the problem.

>   The other angle I am trying to research is whether asthma,
>allergies, and sinus problems are significantly worse in urban areas
>where there is air pollution and smog. I am almost certain they are.

Unfortunately pollution is high even in the mountains.  It gets carried across
the continent.

But yes those ailments do tend to be worse in polluted areas.

>If I don't have a fungal infection, then it could be I am reacting to
>some pollutant in the air. I would like to test for that by taking a
>vacation trip to Bora Bora for a couple of months   ;-)

A vacation trip is a good idea.

Indoor polluion is just as likely to be a major factor.

>   But since the sinusitis is bad all day, every day, and doesn't seem
>to be related to the season, or get better as the quality of the air
>improves  temporarily, it kind of points to an infection.

I would not be positive of that.  I though that for  a long tiem myself until I
finally got real improvement by improving indoor air (just increase ventilation
from outside).
Murray Grossan - 19 Jun 2005 22:41 GMT
On 6/18/05 7:31 PM, in article s5l9b1hu6r1emargvkfetec07g74e4u310@4ax.com,

>  But since the sinusitis is bad all day, every day, and doesn't seem
> to be related to the season, or get better as the quality of the air
> improves  temporarily, it kind of points to an infection.

There is a condition called vasomotor rhinitis. Not an allergy or fungal or
bacterial infection. Suggest you read up on that.  Astelin nasal spray is
indicated for this, as are other products.
Shirley Thebaglady - 20 Jun 2005 10:49 GMT
I have allergies and get sinusitis often.
This winter was a bad one fo me.
I had to use Simply Saline rinses 2x a day and  nasal spray of AYR
(otc).
This was prescribed by my MD last Fall. She will only give me a
prescription if I am imflamed or infection. Nasacort.

Hubbys MD prescribes nasal Med. Rhinacort daily 2x a day.
No saline rinses at all.

shirley
Murray Grossan - 24 Jun 2005 04:50 GMT
On 6/20/05 2:49 AM, in article
3604-42B69117-866@storefull-3137.bay.webtv.net, "Shirley Thebaglady"
<thebagladyshirleyann@webtv.net> wrote:

> nasal spray of AYR
I believe that has a preservative Benzalkonium which may irritate the nose.
augustwestern - 19 Jun 2005 03:16 GMT
> WHen my sinuses get severely congested, I can only clear them by
> "sucking" the secretions down, inhaling abruptly through the nose,
[quoted text clipped - 9 lines]
>    What antihistamine or decongestant usually works best for people
> with  a fungal sinusitis?

Have you tried regular saline irrigation for at least 60 days? This might
help clean out much of that phlegm. I agree with Don that you need to try a
steroid spray like Flonase or Nasonex and see if you can get by with less
antihistamines.   AW
Geronimo - 21 Jun 2005 20:52 GMT
  That could be a large part of my problem...I just haven't stuck
with anything long enough to see any good results. I had started
taking Claritin again because my dentist was telling me that she had
the same problem with sinus congestion & PND, and Claritin finally
worked for her. I tried Clarinex  for several weeks in 2000,  and
although it gives some people immediate relief, it had no more effect
on my congestion than taking a sugar pill!  She had to take CLaritin
for *6 months* before she got over the congestion, and it was a full
two months before she saw an improvement.
   I will try switching to Nasonex. The allergist back in 2000 had me
try Nasonex,and two or three other nasal sprays... but they  did
nothing....but then again maybe I was too quick to give up on it?
 I have been taking a saline nasal spray called Ocean  the past few
days, it seems to sooth a little bit and help drain sinuses. ALso, I
have found  that sucking on ALtoids peppermint has a soothing effect
on the sinuses, its very strong.
      Also, I need to know what the exact recipe is for the hydrogen
peroxide/ kosher salt/ baking soda nasal irrigation....and try that
also. Please send a link for that info.   Thanks, Jim

>> WHen my sinuses get severely congested, I can only clear them by
>> "sucking" the secretions down, inhaling abruptly through the nose,
[quoted text clipped - 14 lines]
>steroid spray like Flonase or Nasonex and see if you can get by with less
>antihistamines.   AW
CanDo - 22 Jun 2005 12:48 GMT
The link for the sinus flooding with peroxide, baking soda and kosher salt
is:

http://home.bellsouth.net/p/PWP-upsidedown

>    That could be a large part of my problem...I just haven't stuck
> with anything long enough to see any good results. I had started
[quoted text clipped - 34 lines]
> >steroid spray like Flonase or Nasonex and see if you can get by with less
> >antihistamines.   AW
augustwestern - 23 Jun 2005 01:10 GMT
>    That could be a large part of my problem...I just haven't stuck
> with anything long enough to see any good results. I had started
[quoted text clipped - 15 lines]
> peroxide/ kosher salt/ baking soda nasal irrigation....and try that
> also. Please send a link for that info.   Thanks, Jim

> >Have you tried regular saline irrigation for at least 60 days? This might
> >help clean out much of that phlegm. I agree with Don that you need to try a
> >steroid spray like Flonase or Nasonex and see if you can get by with less
> >antihistamines.   AW

I don't have fungal sinusitis. I do have chronic (sometimes acute) sinusitis
along with severe allergies. It took me many months of experimenting with
various allergy medicines and also beginning allergy shots again (for the
3rd time) plus doing saline irrigation twice daily every day to get my
sinusitis under some degree of control.

I use a Hydropulse for sinus irrigation.
http://www.hydromedonline.com/

My personal saline mix is: What ended up working best for me was using no
iodine sea salt that was
clearly marked as being pure with no anti-caking agents or any other
additives. Look for pure baking soda with no added ingredients and then I
use distilled water. I use 6 teaspoons salt and 2 tsp. baking soda per
gallon of water. This premixed gallon of saline lasts me for 4-5 days or
about 8-10 full irrigations. Distilled water runs about .58 a gallon if you
look
around. Your mileage and salt/soda % may vary from mine.

I needed something I could use to wash out my sinuses every day, so I don't
do the hydrogen peroxide recipe. It took about 2 weeks of  twice daily
irrigation to start really washing all the gunk out. It took about 2 months
daily irrigation until I could say I was free of sinus infection.

I also use Flonase for a steroid spray 2X daily and Astelin for an
antihistamine 2 X daily.

best,   AW
augustwestern - 23 Jun 2005 19:40 GMT
> >        Also, I need to know what the exact recipe is for the hydrogen
> > peroxide/ kosher salt/ baking soda nasal irrigation....and try that
[quoted text clipped - 28 lines]
>
> best,   AW

My account above neglects to mention that before my sinusitis improved I had
seen my internist many times, an ENT who was also certified in treating
allergy, an infectious disease specialist who did a CT scan of my sinuses
and I saw the top sinusitis Dr at a large teaching hospital. All the Drs
except the teaching specialist said I needed sinus surgery to correct
various defects in my nose and sinuses but the teaching Dr said daily
irrigation with the Hydropulse was what would help me stay more free from
chronic sinus infections.     AW
 
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