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Medical Forum / Diseases and Disorders / Prostatitis / May 2005Fluoroquinolone induced tendonitis - what to do about it
I have had fluoroquinolone induced tendonitis on two occasions. The first time was no big deal - just quit taking the fluoroquinolone and the problem resolved. The 2nd time - even though I had already stopped the pain got progressively worse. It became excruciating if I tried to move the affected limb, and there was no position in which I could get comfortable. NSAIDS did not seem to help. An out of control imflammatory cascade. I decided I had no choice but to go for the big gun - prednisone. I started with 30 mg., b.i.d, then tapered to 20 and 15 over the next two days. Needed to stay at the 15 mg dose for a few days. Am now down to 10 mg. on day 7 - am feeling decent, some soreness, but much better. My advice to anyone with severe fluoroquinolone induced tendonitis - do a prednisone burst and taper without delay. Delay means accumulating inflammatory damage, IMHO. I suffered from this as well. I offer the following advise: 1 - Quinolones can be dangerous and useful - so see a doctor. 2 - Quinolone indiced tendonopathy is a known problem. 3 - In can be mitigated (not cured) by using a high quality magnsium supplement (about 400% of the usrda) daily but not within 6 hours of taking a quinolone (i.e. if you take levaquin once a day - take the magnesium 12 hours before/after it). 4 - It takes about a week for the magnesium to start the healing process in the tendon. I did a lot of research on this - what it is - is that the quinolone creates a "magnesium/calcium" like deficiancy in the tendons. See this article...... http://aac.asm.org/cgi/content/abstract/39/9/2013?ijkey=88e542d126588266b4a79bcb 86552e132b58a077&keytype2=tf_ipsecsha > I have had fluoroquinolone induced tendonitis on two occasions. The > first time was no big deal - just quit taking the fluoroquinolone and [quoted text clipped - 12 lines] > a prednisone burst and taper without delay. Delay means accumulating > inflammatory damage, IMHO. |
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