Worth noting that the conclusion is not supported by the paper, since
the ability to kill in the test tube doesn't always correlate with
clinical efficacy.

Eur Urol. 2004 Nov;46(5):647-650.

In Vitro Activity of Fluoroquinolones, Azithromycin and Doxycycline
against Chlamydia Trachomatis Cultured from Men with Chronic Lower
Urinary Tract Symptoms.

Smelov V, Perekalina T, Gorelov A, Smelova N, Artemenko N, Norman L.

Medical Department, St. Petersburg State University, St. Petersburg,
Russia; City Sport Medical Center, St. Petersburg, Russia.

INTRODUCTION:: Little is known about chlamydia survival in the
presence of fluoroquinolones in patients with chronic prostatitis
syndrome (CPS). In vitro activities of four fluoroquinolones,
azithromycin and doxycycline against C. trachomatis in patients with
CPS being not treated with antibiotics earlier were investigated and
compared. MATERIAL AND METHODS:: Chlamydia survival in 304 patients
with CPS being not treated with antibiotics earlier was analysed and
compared. Infection by C. trachomatis was determined in the urethra
and expressed prostatic secretion by cell culture test. RESULTS::
Azithromycin and ofloxacin were found to be the most active
antichlamydial agent with ciprofloxacin and doxycycline being least
active. CONCLUSION:: Ofloxacin can be recommended as the primary drug
in the treatment of chlamydia-infected patients with CPS. The decision
on the prescription of other fluoroquinolones should be made
individually. The investigation of chlamydia survival in the presence
of antibiotics in patients with CPS and C. trachomatis prior to
treatment is recommended.