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Medical Forum / Diseases and Disorders / Prostatitis / February 2004

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Enterococcus faecalis

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ø¤º-----IDEA MAN-----º¤ø - 11 Feb 2004 01:45 GMT
I bet a substantial number of CPPS sufferers have enterococcus faecalis in
their prostatic secretions. Huh? Am I wrong about this doctors? Anyways,
it's interesting enterococcus faecalis can cause inflammatory bowel disease
yet when it's isolated in CPPS sufferers it's normal flora.

Am J Pathol. 2002 Jun;160(6):2253-7.  Related Articles, Links

Enterococcus faecalis induces inflammatory bowel disease in interleukin-10
knockout mice.

Balish E, Warner T.

Department of Surgery, University of Wisconsin Medical School, Madison,
Wisconsin, USA. balish@musc.edu

Germ-free interleukin-10 knockout (IL-10 KO) mice developed inflammatory
bowel disease (IBD) after they were colonized with a pure culture of
Enterococcus faecalis. E. faecalis not only induced IBD (primarily in colon
and rectum) but rectal dysplasia and adenocarcinoma was also found in the
IL-10 KO mice. Conventional (complex-intestinal flora) IL-10 KO mice
developed IBD within 10 to 15 weeks of age and showed more pathology in the
cecum (typhlitis) than we observed with E. faecalis-induced IBD in
gnotobiotic IL-10 KO mice. Conversely, neither germ-free IL-10 mice nor
IL-10 KO mice colonized as adults, with a pure culture of Candida albicans,
Escherichia coli, Lactobacillus casei, L. reuteri, L. acidophilus, a
Bifidobacterium sp., Lactococcus lactis, or a Bacillus sp. developed IBD
during the 25- to 30-week study. E. faecalis is a common intestinal microbe
of man and animals that can trigger IBD, dysplasia, and carcinoma in a
genetically susceptible murine host.

PMID: 12057927 [PubMed - indexed for MEDLINE]
Cameron - 11 Feb 2004 14:34 GMT
> I bet a substantial number of CPPS sufferers have enterococcus faecalis in
> their prostatic secretions. Huh? Am I wrong about this doctors? Anyways,
[quoted text clipped - 27 lines]
>
> PMID: 12057927 [PubMed - indexed for MEDLINE]

I've also been perplexed on why some studies rule bacteria in the
prostate as "normal" or a "non pathogen."  But when found anywhere
else in the body it is ruled the source of the problem and commands an
immune response!   In fact, when the three types of bacteria were
found in my prostate secretions, I asked a pathologist that very
question.  His explained that the bacteria I called out were a problem
no matter where they would be found, without a doubt.  Of course, I
elected to move forward with aggressive abx treatment, some do not.

Gotta love these studies.  Can be very confusing for the average joe.
NatSelection - 11 Feb 2004 20:07 GMT
>I've also been perplexed on why some studies rule bacteria in the
>prostate as "normal" or a "non pathogen."  But when found anywhere
[quoted text clipped - 6 lines]
>
>Gotta love these studies.  Can be very confusing for the average joe.

This is why I don't want to get a MD. Can you imagine trying to explain a
complex disease and the treatments for it to a person like this?!
This dim-witted ex-cop does not know the first thing about science or medicine
and is absolutely impervious to reason. His idiotic statements show that he
doesn't know what commensalism is, and he lacks the brain power
to understand the studies he's read  (or tried to read).

What astounding ignorance!
Cameron - 12 Feb 2004 14:53 GMT
> >I've also been perplexed on why some studies rule bacteria in the
> >prostate as "normal" or a "non pathogen."  But when found anywhere
[quoted text clipped - 13 lines]
> doesn't know what commensalism is, and he lacks the brain power
> to understand the studies he's read  (or tried to read).

I think the rest of us are also glad you are not an MD if this is a
measurement of your patience.  We really need to get more people
posting and discussing this complex issue.  However, I'm sure the
personal attacks are keeping the averag "joe" from chiming in.  This
is unfortunate.  To date, there is no definitive or agreed upon
therapy for this problem/problems.  My message to readers is to keep
looking, try the different therapies and find one that works.  Dont
give up.

> What astounding ignorance!
salo - 12 Feb 2004 21:21 GMT
please can  anybody advice  on  what  to  take  for bladder  pain and disconfort
---IDEA MAN--- - 13 Feb 2004 03:28 GMT
"salo" < wrote...

> please can  anybody advice  on  what  to  take  for bladder  pain and disconfort

Go to a pain clinic!

After that, research and talk with other sufferers about treatments.

Get a medium sized container and fill it with water. Freeze this and place
it on your pubic bone when you have time to rest at home. Switch between
heat and ice. This should help.
niceshyguymiami - 23 Feb 2004 05:00 GMT
J. Curtis Nickel, MD says:

The significance of gram-positive cocci in patients with chronic prostatitis
has been debated for most of the 20th century. As described above,
gram-positive cocci were accepted as etiologic agents for most of the century.
However, over the last 3 decades, the consensus was that these organisms are
seldom, if ever, causative. However, it is now generally agreed that
Enterococcus faecalis may cause chronic bacterial prostatitis and related
recurrent enterococcal bacteriuria.

I
Mast Cells - 23 Feb 2004 09:10 GMT
niceshymiamiguy@aol.com wrote:
> J. Curtis Nickel, MD says:
>
[quoted text clipped - 6 lines]
>Enterococcus faecalis may cause chronic bacterial prostatitis and related
>recurrent enterococcal bacteriuria.

Paul, from where did that excerpt come?
 
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