GERD meds that DONT inflame the prostate? (Prilosec isn't working...)

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looking4answers - 30 Nov 2003 03:36 GMT

I have had a serious bout of prostatitis after taking Prilosec...I
have heard similar stories from others about Aciphex and Prilosec.

Has anyone here had a similar experience

Can anyone recommend a PPI that does not inflame the prostate?
Protonix?
Prevacid?

Thanks,

Mark

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YO - 30 Nov 2003 04:09 GMT

I have been struggling with CP for three years and I have been taking
prilosec for seven years. This is the first time I hear about this
connection. I see my urologists monthly and he knows I am taking omeprazole,
so I wonder if this claim have any veracity. Prevacid, protonix, nexium are
in the same family of drugs as prilosec (proton pump inhibitors), I might go
back to ranitidine just to see if it makes a difference in my symptoms.

Yo

> I have had a serious bout of prostatitis after taking Prilosec...I
> have heard similar stories from others about Aciphex and Prilosec.
[quoted text clipped - 8 lines]
>
> Mark

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looking4answers - 30 Nov 2003 20:14 GMT

> I have been struggling with CP for three years and I have been taking
> prilosec for seven years. This is the first time I hear about this
[quoted text clipped - 4 lines]
>
> Yo

Well this is all really strange...I am not 100% sure about the
connection.

I had one prostate infection 4 years ago, and ever since then I have
been fine (except when I took dramamine, forgetting that
antihistamines cause inflamation for me).

I just started taking Prilosec 5 days ago, and then 3 days into it I
have a bladder/prostate infection. I have no real evidence that this
was the cause, but in Prilosec's PDR the following is listed:

Urogenital: Interstitial nephritis (some with positive rechallenge),
urinary tract infection, microscopic pyuria, urinary frequency,
elevated serum creatinine, proteinuria, hematuria, glycosuria,
testicular pain, gynecomastia

Here is a link to the PDR entry.
http://www.schoolasthmaallergy.com/2002-2003/sections/medications/PackageInsert/
03802428.HTM

I plan to ask my Dr. about this on monday.

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swantzswanson - 01 Dec 2003 01:30 GMT

a few people have posted that zantac has helped.in some people
however zantac causes impotence. you may want to try it and see

> I have been struggling with CP for three years and I have been taking
> prilosec for seven years. This is the first time I hear about this
[quoted text clipped - 17 lines]
> >
> > Mark

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looking4answers - 02 Dec 2003 23:22 GMT

> > > I have had a serious bout of prostatitis after taking Prilosec...I
> > > have heard similar stories from others about Aciphex and Prilosec.
[quoted text clipped - 8 lines]
> > >
> > > Mark

Well...Yesterday my Dr. said my prostate was normal and he didn't
detect any kidney stones, but he thought I was either passing a small
one, or had a minor prostate infection. I asked about hte Prilosec and
in typical doctor fashion he said "no way...that's really rare...here
take CIPRO XR twice a day (500mg)"

I couldn't afford to fill the CIPRO prescription yesterday, so I just
waited...and after 3 days being off Prilosec I am 50% better. Did I
just have an infection that cleared up on its own? Did the prilosec
cause the inflamation? Who knows....
I am going to call him tomorrow and see if he still wants me on the
Cipro..

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looking4answers - 10 Dec 2003 23:57 GMT

> I couldn't afford to fill the CIPRO prescription yesterday, so I just
> waited...and after 3 days being off Prilosec I am 50% better. Did I
> just have an infection that cleared up on its own? Did the prilosec
> cause the inflamation? Who knows....
> I am going to call him tomorrow and see if he still wants me on the
> Cipro..

Well it turns out it was NOT from the prilosec, but I think it was
from the pepcid?
I was takign pepcid occasionally at the same time, and stopped taking
it when I stopped the Prilosec. I then started taking zantac a few
days later...and BINGO...back again.
Could this be a reaction I have to H2 blockers?

So I stopped taking Zantac and started with the prilosec again. No
problems this time (except that prilosec doesn't work for my GERD).

I usually have this reaction to OTC anti-histamines...but I thought
that H2 blockers didn't have much systemic activity...

So either it's the H2's or a coincidence

hmm

Mark

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Anajnas - 26 Dec 2003 07:38 GMT

Why did you conclude it isnt the Prilosec? I am very curious. I have
had about 6 bouts of prostatitis in the last 5 years. Typically
doesnt last more than 4-6 weeks and responds well to Cipro. I believe
the prostate massage also helped me. However I started taking
Prevacid in July and doubled my dose in August. I got a case of
prostatitis in the end of September that hasnt responded to any
treatment. I am now taking the regular dose of Prevacid about 5 days
a week and your experience makes me wonder if I am a rare case of
reacting to Prevacid? I will completely stop taking Prevacid for the
next 4 weeks and see if that cures my problem.

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