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Medical Forum / Diseases and Disorders / Prostatitis / November 2003

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Can a UTI cause an elevated PSA?

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jplasater@NOSPAMjuno.com - 10 Nov 2003 23:53 GMT
About a month ago I came down with a urinary tract infection.  I
initially started running fever from 101-102.   Thinking it was flu, I
let it go for several days until frequent urination started.  I then
went to a local doc who did a urinary analysis and said that I had an
infection.  He prescribed tequin(400mg per day for 10 days) .   That
cured the infection.   About 3 weeks later,  I went to my local doc
for a DRE and PSA.   The PSA came back 17.4.    

About 5 days after the PSA of 17.4, I went back to the same doctor and
he reran the PSA with a result of 14.1.   What is the significance of
that?    Does it confirm that I probably am having the effects of the
UTI and that it is slowly reducing to normal levels.  My doc has
scheduled for me to see a urologist in about a week.   Meanwhile, I am
trying to understand the significance of the high number and the drop
in 5 days.  Thanks
jplasater@NOSPAMjuno.com - 11 Nov 2003 02:31 GMT
I forgot to say that for the past 10 years that I have been having an
annual PSA and DRE, my PSA has always been about ".1".  

>About a month ago I came down with a urinary tract infection.  I
>initially started running fever from 101-102.   Thinking it was flu, I
[quoted text clipped - 11 lines]
>trying to understand the significance of the high number and the drop
>in 5 days.  Thanks
Larry Gray - 12 Nov 2003 22:43 GMT
Hello,
   According to my uro, yes. When I had a PSA of 8.5, he prescribed Cipro
for three weeks and tested it again (it went up).

Hope this helps,
Larry

> I forgot to say that for the past 10 years that I have been having an
> annual PSA and DRE, my PSA has always been about ".1".
[quoted text clipped - 14 lines]
> >trying to understand the significance of the high number and the drop
> >in 5 days.  Thanks
Andy - 13 Nov 2003 10:04 GMT
I had a UTI earlier this year. Lasted for many weeks.
I saw a urologist who did a digital rectal examination of my prostate.
I had a PSA blood test done the following day which came out at 24. Because
of the high reading the urologist  followed this up with a prostate biopsy,
about three weeks later, which proved negative. I assume the digital
examination caused the high PSA but no doubt  the UTI would have also played
a part in the high reading.

> > I forgot to say that for the past 10 years that I have been having an
> > annual PSA and DRE, my PSA has always been about ".1".
[quoted text clipped - 14 lines]
> > >trying to understand the significance of the high number and the drop
> > >in 5 days.  Thanks
Idea Man - 13 Nov 2003 14:18 GMT
"Andy"  wrote...

> of the high reading the urologist  followed this up with a prostate
BIOPSY,
> about three weeks later, which proved negative.

Hi Andy!

Hope your doing well. I'm curious about the prostate biopsy? Do you mind
posting if there was any change in your CPPS symptoms before or after the
procedure? Do you think it made your symptoms worse? How many cores did they
take out?

Thanks much.

¸¸.·*´¯`v´¯`*·.¸¸ × * × ¸¸.·*´¯`v´¯`*·.¸¸
avocet - 13 Nov 2003 17:55 GMT
> I forgot to say that for the past 10 years that I have been having an
> annual PSA and DRE, my PSA has always been about ".1".

A couple of tips regarding the PSA.

According to this Brazilian study,

http://www.mdlinx.com/UrologyLinx/thearts.cfm?artid=768956&specid=10

DRE does not raise PSA values to any significant level.  However, it seems
sensible to me to ask for the PSA blood draw before the DRE is done.

Further, make sure you do not have an ejaculation for at least 48 hrs prior
to the time of the PSA blood draw.  A recent ejaculation will cause a higher
PSA reading.

And, your course of antibiotics may not have been quite long enough to kill
off the urinary infection.  If any infection remains, that could drive up
your numbers.  Odd you should go so quickly from a very low number to a high
one.

Jim
jplasater@NOSPAMjuno.com - 14 Nov 2003 00:24 GMT
I went to the urologist today.  After another DRE and review of my
situation he said that he was almost certain that the high PSA came
from the UTI.  He didn't even take another PSA.  He gave me two
antiobiotic prescriptions.  I take the first one during the last week
of Nov.  The second one comes during the last week of Dec.  Then I go
back to him at the end of Jan for another PSA.   He said that, if he
did a biopsy now he is almost certain that he would find inflamed
tissue non malignant.  He said that since I had a PSA of less than 1
for almost 10 years prior, prostate cancer would not advance so as to
produce a 17 in one year.  Only the UTI would do that.   Does that
make sense to you?  

>About a month ago I came down with a urinary tract infection.  I
>initially started running fever from 101-102.   Thinking it was flu, I
[quoted text clipped - 11 lines]
>trying to understand the significance of the high number and the drop
>in 5 days.  Thanks
Robert - 14 Nov 2003 03:45 GMT
> I went to the urologist today.  After another DRE and review of my
> situation he said that he was almost certain that the high PSA came
[quoted text clipped - 7 lines]
> produce a 17 in one year.  Only the UTI would do that.   Does that
> make sense to you?

No, he is an idiot.  Only an idiot would order a PSA during a UTI attack AND
THEN say it is invalid because of the UTI.  WTF.
He should have waited until the UTI is resolved BEFORE doing a PSA.  Now you
are worried about a high result test that he shouldn't have done and he
refuses to act on it.
Does that make sense to you??????

> >About a month ago I came down with a urinary tract infection.  I
> >initially started running fever from 101-102.   Thinking it was flu, I
[quoted text clipped - 11 lines]
> >trying to understand the significance of the high number and the drop
> >in 5 days.  Thanks
avocet - 14 Nov 2003 18:32 GMT
> No, he is an idiot.  Only an idiot would order a PSA during a UTI attack AND
> THEN say it is invalid because of the UTI.  WTF.
> He should have waited until the UTI is resolved BEFORE doing a PSA.  Now you
> are worried about a high result test that he shouldn't have done and he
> refuses to act on it.
> Does that make sense to you??????

_______

One of the keys to PSA reading is to establish a base of "normals" from
which to compare as one ages.  jplasater has a good base history.

I agree with what Robert is saying.  However, in doctor training the strong
message is given to students to test for PSA (our only, albeit flawed,
monitor) whenever there is a prostate problem.  What is sometimes left out
in the training is that the inflamed prostate, or urethra in jplasater's
case, will give a "false high" outcome to the blood draw.  Seasoned
urologists do not freak at one, sudden, bad reading.  They know that when
the patient overcomes the infection things should drop back gradually to
"normal."  Still, it does not make a whole lot of sense to do a PSA on
someone with a great history during the time he is symptomatic of UTI.  But
this happens.  Been there.

Jim
Robert - 14 Nov 2003 21:58 GMT
> _______
>
[quoted text clipped - 13 lines]
>
> Jim

Look at what the doc told him, "since I had a PSA of less than 1
for almost 10 years prior, prostate cancer would not advance so as to
produce a 17 in one year.  Only the UTI would do that.  ".
So if he had gotten  say a 6 PSA instead of a 17 would he have done a biopsy
because it would be more consistent with cancer?
He gave a bullshit answer.  It should not have been done period.
The logic is that cancer patients don't get UTI's is also bullshit which is
why he wants to repeat the PSA after the UTI resolves.
jplasater@NOSPAMjuno.com - 14 Nov 2003 22:33 GMT
Thanks for the responses.   Actually, this is the scenario.  I knew I
was due my annual PSA and scheduled to have it done.  Then before the
apt. to have it done, I contracted the infection.  Initially, I
thought the fever was the flu but, after I started having to urinate
every 5 minutes I knew something was up.  That is when I went to a
emergency room  doc who diagnosed the UTI and gave me a round of
antiobiotics.   About 3 weeks after the UTI was over, I scheduled the
annual PSA test.  Heck, I did not know the UTI would drive the PSA out
of sight and I did not tell the family doc who did the test.  When the
results came in as 17, I started doing some investigation.  Then I
called the family doc who did the PSA and told him I had had a UTI.
He referred me to the urologist who put 2 and 2 together and realized
that my high PSA was the result of the UTI.   Sorry about the
confusion

>I went to the urologist today.  After another DRE and review of my
>situation he said that he was almost certain that the high PSA came
[quoted text clipped - 23 lines]
>>trying to understand the significance of the high number and the drop
>>in 5 days.  Thanks
 
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