Here are 2 abstracts with actual data. Conclusion:

More evidence for an autoimmune cause in CPPS
Lack of evidence of the role of chlamydia

Andrologia. 2003 Oct;35(5):294-9.

Immunological alterations in the ejaculate of chronic prostatitis
patients: clues for autoimmunity.

John H, Maake C, Barghorn A, Zbinden R, Hauri D, Joller-Jemelka HI.

Clinic of Urology Institutes of Anatomy Clinical Pathology Medical
Microbiology Clinical Immunology, University Hospital and University
of Zurich, Zurich, Switzerland.

The aim of this prospective study was to observe immunophenotypic
patterns in the ejaculate of patients with noninflammatory chronic
pelvic pain syndrome (Cat IIIB CPPS) and to test for a possible
autoimmune aetiology. Thirty-five patients of a total of 88 patients
with chronic prostatitis Cat IIIB were consecutively selected. Monthly
ejaculate testing was carried out for IgG, IgA, IgM, IL-1alpha, sIL-2R
and IL-6. The control group for ejaculate analysis was composed of 96
normal ejaculates (according to the WHO criteria). Immunohistochemical
detection of CD3 cells (T lymphocytes) and CD20 cells (B lymphocytes)
was performed in 71 biopsy cylinders of Cat IIIB CPPS patients and in
25 prostate biopsy cylinders of subjects without symptoms or
obstruction. Intra-acinar T-lymphocytic infiltrates were dominated by
T-cytotoxic cells (P = 0.05). Ejaculate IL-6 and ejaculate IgA
increased significantly and dropped again, correlating with a release
of clinical symptoms. Inflammatory ejaculate interleukin
concentrations correlated with the immunohistochemical findings with
presence of large numbers of T cells (all P-values </= 0.01).
Immunomodulation was performed in a pilot series of three patients by
five monthly cycles of IgG (Sandoglobulin(R)), 1 g kg-1 body weight.
Immunomodulation with IgG decreased pain moderately and did not change
ejaculate interleukin and immunoglobulin concentrations. In summary,
interleukin and immunoglobulin determinations in the ejaculate
revealed an inflammatory process even in Cat IIIB CPPS. The findings
of intra-acinar T-cell rich infiltrates and the associated
inflammatory reaction may indicate a possible autoimmune component in
the aetiology of CPPS. Exact origin and role of interleukin changes in
the ejaculate of CPPS patients need to be further evaluated.
Unfortunately, pilot series with immunomodulation with IgG do not seem
to provide clear clinical benefit.

2: Andrologia. 2003 Oct;35(5):263-5.

Chlamydial and ureaplasmal infections in patients with nonbacterial
chronic prostatitis.

Badalyan RR, Fanarjyan SV, Aghajanyan IG.

Department of Urology, NIH, Yerevan, Armenia.

Our study was designed to establish the necessity of routine
evaluation of patients with inflammatory (IIIA) and noninflammatory
(IIIB) types of nonbacterial prostatitis (NBP) for chlamydial and
ureaplasmal infections. From 1999 to 2001, 165 patients with a mean
age of 35 years (range 20-54 years) were evaluated for the syndrome of
chronic prostatitis. The evaluation included scoring with Prostate
Symptom Score Index (PSSI) and NIH Chronic Prostatitis Symptom Index
(CPSI), Meares-Stamey test and culturing of post-massage urine portion
(fourth glass). In all cases, polymerase chain reaction (PCR)-testing
of the semen was performed to establish the persistence of Chlamydia
trachomatis (ChT) and Ureaplasma urealyticum (UU). Based on laboratory
findings (four glass test and post-massage urine culture), in 69 (42%)
of 165 cases, NBP was diagnosed, which includes 30 patients with type
IIIA and 39 with type IIIB of NBP. According to semen PCR tests, in 11
(36.6%) of 30 cases with IIIA type of NBP, chlamydial (six cases),
ureaplasmal (four cases) and a mixture of both (one case) infections
were described. Among 39 patients with IIIB type of NBP test was
positive in 14 cases (36%), where UU was presented in eight and ChT in
six cases. In patients with previously diagnosed inflammatory as also
noninflammatory NBP, according to four glass test, chlamydial and/or
ureaplasmal infections can be presented. Although their role in
pathogenesis of prostatitis remains speculative, however, testing for
infections is highly recommended.